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The map label for this gene is 119897892

Identifier: 119897892

GI number: 119897892

Start: 1755933

End: 1756850

Strand: Reverse

Name: 119897892

Synonym: azo1601

Alternate gene names: NA

Gene position: 1756850-1755933 (Counterclockwise)

Preceding gene: 119897893

Following gene: 119897891

Centisome position: 40.15

GC content: 70.04

Gene sequence:

>918_bases
GTGAAGCTGTACTACGCCGACCATTTCGTCCTGCCGCTGCCGCCGGGCCACCGCTTCCCGATGGAAAAGTACAGCCGGCT
GCGGGCGCGGCTCGTCGCAAGCGGCGTGTTTGGCGACGGCGACCTGCGTGAGCCCGCGGCCGCCACCGACGCCGAACTCG
CCCGCGCCCACGATCCGGCCTATGTGGCACGCGTGGCGCAAGGCGAACTCGCGGCGGACGAGATCCGCCGGATCGGCTTT
CCGTGGTCGGAAGCCATGGTCGAACGCTCGCGCCGCTCCGCCGGCGCGACGCTTGCCGCCTGCCGCAGCGCGCTCGACGA
AGGCTGCGGGATCAATCTGGCGGGTGGCACCCACCACGCCCATCGCGATTTCGGCTCCGGCTTCTGCGTGTTCAACGACG
CCGCGGTGGCCGCACTGGCGATGCGTGCCGAAGGCCGGGTGCAACGCGTCGCGGTTGTCGATTGCGACGTGCATCAGGGC
GACGGCACCGCCGCCATCCTCGCCGGCGTACCCGAGGTATTCACCTGCAGCCTGCACGGCGCCAAGAATTTTCCGTTCCG
CAAGGCGCGCAGCGATCTCGACGTCGAACTCCCCGACGACACGGGCGACGAGCCTTACCTGGCGGCGCTCGACAACGCGC
TCGAGCGCGTGTTCAGCGAGTTCCGCCCGCAACTGCTGATCTACCTCGCGGGGGCGGACCCCTACGCCGGCGACCGCCTT
GGCCGACTTGCGCTGAGCAAACAGGGCCTGGCGGAACGCGACCGGCGCGTCCTTGCACGCTGCCACGCCAGCGGCCTGCC
CATCGCCATTGCGATGGCCGGCGGGTACGCCAGCGAGATCGACGATACGGTGGACATCCACTACCGCACCGTCCTCACCG
CCGCAGGCCTTTTCCACCGCCCAGCCGGCGTGCGATGA

Upstream 100 bases:

>100_bases
GAGGGCGAACTCGCCGCGGTGTATGGCGACAGCGAAGCCGTGCTGGCGCCGCTGATCGAGTGACGCGGCCGGCACGCCGG
CCGCCCTCGGGGCTGCATTC

Downstream 100 bases:

>100_bases
GCGCAGGCTCGCCATCAGGTTGGACGCTTTACGGCGTGGACTTCACGTCGGCACCGCGCGCACGCAAGCCGATCGTGATT
GCGCGCGGACACGCCACCGG

Product: histone deacetylase family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 305; Mature: 305

Protein sequence:

>305_residues
MKLYYADHFVLPLPPGHRFPMEKYSRLRARLVASGVFGDGDLREPAAATDAELARAHDPAYVARVAQGELAADEIRRIGF
PWSEAMVERSRRSAGATLAACRSALDEGCGINLAGGTHHAHRDFGSGFCVFNDAAVAALAMRAEGRVQRVAVVDCDVHQG
DGTAAILAGVPEVFTCSLHGAKNFPFRKARSDLDVELPDDTGDEPYLAALDNALERVFSEFRPQLLIYLAGADPYAGDRL
GRLALSKQGLAERDRRVLARCHASGLPIAIAMAGGYASEIDDTVDIHYRTVLTAAGLFHRPAGVR

Sequences:

>Translated_305_residues
MKLYYADHFVLPLPPGHRFPMEKYSRLRARLVASGVFGDGDLREPAAATDAELARAHDPAYVARVAQGELAADEIRRIGF
PWSEAMVERSRRSAGATLAACRSALDEGCGINLAGGTHHAHRDFGSGFCVFNDAAVAALAMRAEGRVQRVAVVDCDVHQG
DGTAAILAGVPEVFTCSLHGAKNFPFRKARSDLDVELPDDTGDEPYLAALDNALERVFSEFRPQLLIYLAGADPYAGDRL
GRLALSKQGLAERDRRVLARCHASGLPIAIAMAGGYASEIDDTVDIHYRTVLTAAGLFHRPAGVR
>Mature_305_residues
MKLYYADHFVLPLPPGHRFPMEKYSRLRARLVASGVFGDGDLREPAAATDAELARAHDPAYVARVAQGELAADEIRRIGF
PWSEAMVERSRRSAGATLAACRSALDEGCGINLAGGTHHAHRDFGSGFCVFNDAAVAALAMRAEGRVQRVAVVDCDVHQG
DGTAAILAGVPEVFTCSLHGAKNFPFRKARSDLDVELPDDTGDEPYLAALDNALERVFSEFRPQLLIYLAGADPYAGDRL
GRLALSKQGLAERDRRVLARCHASGLPIAIAMAGGYASEIDDTVDIHYRTVLTAAGLFHRPAGVR

Specific function: Putative deacetylase [H]

COG id: COG0123

COG function: function code BQ; Deacetylases, including yeast histone deacetylase and acetoin utilization protein

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the histone deacetylase family [H]

Homologues:

Organism=Homo sapiens, GI217272877, Length=274, Percent_Identity=28.4671532846715, Blast_Score=113, Evalue=2e-25,
Organism=Homo sapiens, GI209862883, Length=286, Percent_Identity=28.3216783216783, Blast_Score=112, Evalue=5e-25,
Organism=Homo sapiens, GI8923769, Length=257, Percent_Identity=28.4046692607004, Blast_Score=100, Evalue=1e-21,
Organism=Homo sapiens, GI13128860, Length=299, Percent_Identity=26.4214046822742, Blast_Score=92, Evalue=5e-19,
Organism=Homo sapiens, GI13128864, Length=281, Percent_Identity=32.0284697508897, Blast_Score=89, Evalue=7e-18,
Organism=Homo sapiens, GI13128862, Length=286, Percent_Identity=25.5244755244755, Blast_Score=87, Evalue=3e-17,
Organism=Homo sapiens, GI293336691, Length=276, Percent_Identity=27.1739130434783, Blast_Score=85, Evalue=7e-17,
Organism=Homo sapiens, GI20070354, Length=272, Percent_Identity=27.9411764705882, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI262073092, Length=148, Percent_Identity=31.7567567567568, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI262073088, Length=171, Percent_Identity=29.8245614035088, Blast_Score=74, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI193207430, Length=279, Percent_Identity=30.4659498207885, Blast_Score=119, Evalue=2e-27,
Organism=Caenorhabditis elegans, GI17508561, Length=288, Percent_Identity=27.7777777777778, Blast_Score=95, Evalue=4e-20,
Organism=Caenorhabditis elegans, GI17561978, Length=275, Percent_Identity=26.5454545454545, Blast_Score=84, Evalue=9e-17,
Organism=Caenorhabditis elegans, GI17534739, Length=178, Percent_Identity=30.8988764044944, Blast_Score=83, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17537347, Length=251, Percent_Identity=27.8884462151394, Blast_Score=76, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI193209491, Length=217, Percent_Identity=29.4930875576037, Blast_Score=71, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI17540334, Length=208, Percent_Identity=26.9230769230769, Blast_Score=67, Evalue=8e-12,
Organism=Caenorhabditis elegans, GI17540332, Length=208, Percent_Identity=26.9230769230769, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI193206283, Length=208, Percent_Identity=26.9230769230769, Blast_Score=67, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6321244, Length=288, Percent_Identity=27.0833333333333, Blast_Score=95, Evalue=2e-20,
Organism=Saccharomyces cerevisiae, GI6323999, Length=289, Percent_Identity=25.2595155709343, Blast_Score=91, Evalue=2e-19,
Organism=Saccharomyces cerevisiae, GI6325325, Length=193, Percent_Identity=29.0155440414508, Blast_Score=68, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24649807, Length=284, Percent_Identity=32.7464788732394, Blast_Score=130, Evalue=1e-30,
Organism=Drosophila melanogaster, GI24657891, Length=300, Percent_Identity=27, Blast_Score=90, Evalue=2e-18,
Organism=Drosophila melanogaster, GI24644244, Length=289, Percent_Identity=23.1833910034602, Blast_Score=83, Evalue=3e-16,
Organism=Drosophila melanogaster, GI281360899, Length=286, Percent_Identity=29.7202797202797, Blast_Score=83, Evalue=3e-16,
Organism=Drosophila melanogaster, GI24642146, Length=287, Percent_Identity=30.6620209059233, Blast_Score=82, Evalue=3e-16,
Organism=Drosophila melanogaster, GI24642142, Length=287, Percent_Identity=30.6620209059233, Blast_Score=82, Evalue=3e-16,
Organism=Drosophila melanogaster, GI24642144, Length=287, Percent_Identity=30.6620209059233, Blast_Score=82, Evalue=4e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000286 [H]

Pfam domain/function: PF00850 Hist_deacetyl [H]

EC number: NA

Molecular weight: Translated: 32837; Mature: 32837

Theoretical pI: Translated: 6.58; Mature: 6.58

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLYYADHFVLPLPPGHRFPMEKYSRLRARLVASGVFGDGDLREPAAATDAELARAHDPA
CEEEEECEEEEECCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHCCHH
YVARVAQGELAADEIRRIGFPWSEAMVERSRRSAGATLAACRSALDEGCGINLAGGTHHA
HHHHHHCCCCCHHHHHHCCCCHHHHHHHHHHHHCCHHHHHHHHHHHCCCCEEECCCCCHH
HRDFGSGFCVFNDAAVAALAMRAEGRVQRVAVVDCDVHQGDGTAAILAGVPEVFTCSLHG
HHHCCCCEEEECHHHHHHHHHHCCCCEEEEEEEEEEEECCCCCEEEEECCCCCEEEEECC
AKNFPFRKARSDLDVELPDDTGDEPYLAALDNALERVFSEFRPQLLIYLAGADPYAGDRL
CCCCCHHHHCCCCCEECCCCCCCCCHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCHHH
GRLALSKQGLAERDRRVLARCHASGLPIAIAMAGGYASEIDDTVDIHYRTVLTAAGLFHR
HHHHHHHCCHHHHHHHHHHHHCCCCCCEEEEECCCCHHHCCCCHHHHHHHHHHHHHHHCC
PAGVR
CCCCC
>Mature Secondary Structure
MKLYYADHFVLPLPPGHRFPMEKYSRLRARLVASGVFGDGDLREPAAATDAELARAHDPA
CEEEEECEEEEECCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHCCHH
YVARVAQGELAADEIRRIGFPWSEAMVERSRRSAGATLAACRSALDEGCGINLAGGTHHA
HHHHHHCCCCCHHHHHHCCCCHHHHHHHHHHHHCCHHHHHHHHHHHCCCCEEECCCCCHH
HRDFGSGFCVFNDAAVAALAMRAEGRVQRVAVVDCDVHQGDGTAAILAGVPEVFTCSLHG
HHHCCCCEEEECHHHHHHHHHHCCCCEEEEEEEEEEEECCCCCEEEEECCCCCEEEEECC
AKNFPFRKARSDLDVELPDDTGDEPYLAALDNALERVFSEFRPQLLIYLAGADPYAGDRL
CCCCCHHHHCCCCCEECCCCCCCCCHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCHHH
GRLALSKQGLAERDRRVLARCHASGLPIAIAMAGGYASEIDDTVDIHYRTVLTAAGLFHR
HHHHHHHCCHHHHHHHHHHHHCCCCCCEEEEECCCCHHHCCCCHHHHHHHHHHHHHHHCC
PAGVR
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7678591 [H]