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The map label for this gene is ycfH [H]

Identifier: 119897889

GI number: 119897889

Start: 1753650

End: 1754420

Strand: Direct

Name: ycfH [H]

Synonym: azo1598

Alternate gene names: 119897889

Gene position: 1753650-1754420 (Clockwise)

Preceding gene: 119897888

Following gene: 119897890

Centisome position: 40.07

GC content: 67.44

Gene sequence:

>771_bases
ATGTACGTCGATTCCCACTGTCATCTCGATTTTCCTGACCTGATCGCGCGCGAGGACGAAGTGCTCGCCGCCATGGCGGC
CAACGACGTGCGCCACGCGCTGTGCGTCAGCGTCAAGCTCGAGGATTTTCCGCGTGTTCTCGGCGTGGCCGAACGCCATC
CCGGCCTGTGGGCTTCGGTGGGCGTGCATCCGGACAACGCCGACTGCGAAGAGCCCGATGTCGCGCGGCTGACCGCACTG
GCGGCGCATCCGCGGGTGGTTGCCATTGGCGAGACCGGGCTGGATTACTACTGGCACAAGGACGCGCCGGAATGGCAGCG
GGCGCGCTTTCGCACCCACATCCGCGCCGCGCGCGCCTGTGGCAAGCCGCTGATCGTCCACACCCGTAACGCCGCCGCCG
ACACCCTGCGGCTGATGAACGAGGAAGATGCCGGCGCCGCCGGCGGTGTCATGCACTGTTTCACCGAAACCCGCGAGGTG
GCTGAGGCCGCGCTGGACCTCGGCTTCTACATCTCCTTTTCCGGCATCGTCACCTTCCGCAATGCGGCCGCGCTCAAGGA
GGTCGCCACCCTGGTGCCGCTCGACCGTCTGCTGATCGAGACCGATTCGCCCTATCTGGCGCCGGTGCCGCACCGCGGCC
ACACCAACGAGCCGGCCTGGGTGGTGCATGTGGCGGAGGAGATCGCCCGCCTGCGCGGCGAGCCGCTCAGCCGTATCGCG
GAAGCCACCACCGACAACTTCTTCCGTCTGTTCAGCCATGCGCACCCCTGA

Upstream 100 bases:

>100_bases
AAGGCCCTGCGTCACCGCATCGAGCAGATCCTCGCCGGCCATCTCGGCTCCAATCGCCCCACCCACACGCTCTGACCCGC
GCCCGGCGCGCTGCTCCACG

Downstream 100 bases:

>100_bases
TTCCGCACGCCGTTTCATCCTCGTCGCCGCGCTCGGCGCCTGTTTGTGCTGGGGCCCGGCACGCGCCGGCAGCTACGATG
ACGCCCTGAGTTCCGCGCGC

Product: putative deoxyribonuclease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 256; Mature: 256

Protein sequence:

>256_residues
MYVDSHCHLDFPDLIAREDEVLAAMAANDVRHALCVSVKLEDFPRVLGVAERHPGLWASVGVHPDNADCEEPDVARLTAL
AAHPRVVAIGETGLDYYWHKDAPEWQRARFRTHIRAARACGKPLIVHTRNAAADTLRLMNEEDAGAAGGVMHCFTETREV
AEAALDLGFYISFSGIVTFRNAAALKEVATLVPLDRLLIETDSPYLAPVPHRGHTNEPAWVVHVAEEIARLRGEPLSRIA
EATTDNFFRLFSHAHP

Sequences:

>Translated_256_residues
MYVDSHCHLDFPDLIAREDEVLAAMAANDVRHALCVSVKLEDFPRVLGVAERHPGLWASVGVHPDNADCEEPDVARLTAL
AAHPRVVAIGETGLDYYWHKDAPEWQRARFRTHIRAARACGKPLIVHTRNAAADTLRLMNEEDAGAAGGVMHCFTETREV
AEAALDLGFYISFSGIVTFRNAAALKEVATLVPLDRLLIETDSPYLAPVPHRGHTNEPAWVVHVAEEIARLRGEPLSRIA
EATTDNFFRLFSHAHP
>Mature_256_residues
MYVDSHCHLDFPDLIAREDEVLAAMAANDVRHALCVSVKLEDFPRVLGVAERHPGLWASVGVHPDNADCEEPDVARLTAL
AAHPRVVAIGETGLDYYWHKDAPEWQRARFRTHIRAARACGKPLIVHTRNAAADTLRLMNEEDAGAAGGVMHCFTETREV
AEAALDLGFYISFSGIVTFRNAAALKEVATLVPLDRLLIETDSPYLAPVPHRGHTNEPAWVVHVAEEIARLRGEPLSRIA
EATTDNFFRLFSHAHP

Specific function: Unknown

COG id: COG0084

COG function: function code L; Mg-dependent DNase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tatD DNase family [H]

Homologues:

Organism=Homo sapiens, GI225903424, Length=273, Percent_Identity=30.03663003663, Blast_Score=104, Evalue=1e-22,
Organism=Homo sapiens, GI110349730, Length=263, Percent_Identity=30.4182509505703, Blast_Score=98, Evalue=9e-21,
Organism=Homo sapiens, GI14042943, Length=272, Percent_Identity=27.9411764705882, Blast_Score=96, Evalue=2e-20,
Organism=Homo sapiens, GI110349734, Length=263, Percent_Identity=28.8973384030418, Blast_Score=96, Evalue=3e-20,
Organism=Homo sapiens, GI226061853, Length=269, Percent_Identity=30.1115241635688, Blast_Score=95, Evalue=5e-20,
Organism=Homo sapiens, GI225903439, Length=242, Percent_Identity=28.9256198347107, Blast_Score=93, Evalue=2e-19,
Organism=Homo sapiens, GI226061614, Length=252, Percent_Identity=29.7619047619048, Blast_Score=89, Evalue=4e-18,
Organism=Homo sapiens, GI226061595, Length=226, Percent_Identity=29.646017699115, Blast_Score=76, Evalue=3e-14,
Organism=Escherichia coli, GI1787342, Length=252, Percent_Identity=52.7777777777778, Blast_Score=242, Evalue=1e-65,
Organism=Escherichia coli, GI48994985, Length=242, Percent_Identity=34.7107438016529, Blast_Score=126, Evalue=1e-30,
Organism=Escherichia coli, GI87082439, Length=257, Percent_Identity=31.5175097276265, Blast_Score=124, Evalue=5e-30,
Organism=Caenorhabditis elegans, GI17559024, Length=232, Percent_Identity=27.5862068965517, Blast_Score=99, Evalue=3e-21,
Organism=Caenorhabditis elegans, GI71980746, Length=261, Percent_Identity=26.8199233716475, Blast_Score=94, Evalue=6e-20,
Organism=Caenorhabditis elegans, GI17565396, Length=298, Percent_Identity=25.8389261744966, Blast_Score=75, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17543026, Length=301, Percent_Identity=25.2491694352159, Blast_Score=73, Evalue=1e-13,
Organism=Drosophila melanogaster, GI221330018, Length=254, Percent_Identity=32.2834645669291, Blast_Score=92, Evalue=2e-19,
Organism=Drosophila melanogaster, GI24586117, Length=254, Percent_Identity=32.2834645669291, Blast_Score=92, Evalue=3e-19,
Organism=Drosophila melanogaster, GI24648690, Length=227, Percent_Identity=29.9559471365639, Blast_Score=81, Evalue=5e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015992
- InterPro:   IPR001130
- InterPro:   IPR018228
- InterPro:   IPR012278
- InterPro:   IPR015991 [H]

Pfam domain/function: PF01026 TatD_DNase [H]

EC number: 3.1.21.-

Molecular weight: Translated: 28303; Mature: 28303

Theoretical pI: Translated: 5.97; Mature: 5.97

Prosite motif: PS01137 TATD_1 ; PS01091 TATD_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYVDSHCHLDFPDLIAREDEVLAAMAANDVRHALCVSVKLEDFPRVLGVAERHPGLWASV
CCCCCCCCCCCHHHHHCCHHHHHHHHHHHHHEEHEEEEEHHHHHHHHHHHHCCCCCEEEE
GVHPDNADCEEPDVARLTALAAHPRVVAIGETGLDYYWHKDAPEWQRARFRTHIRAARAC
CCCCCCCCCCCCCHHHHHHHHCCCEEEEECCCCCCEEECCCCCHHHHHHHHHHHHHHHHC
GKPLIVHTRNAAADTLRLMNEEDAGAAGGVMHCFTETREVAEAALDLGFYISFSGIVTFR
CCCEEEEECCCHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHEEEEEEEEEEH
NAAALKEVATLVPLDRLLIETDSPYLAPVPHRGHTNEPAWVVHVAEEIARLRGEPLSRIA
HHHHHHHHHHHHHHHHHEEECCCCCCCCCCCCCCCCCCEEEEHHHHHHHHHCCCHHHHHH
EATTDNFFRLFSHAHP
HHHHHHHHHHHHCCCC
>Mature Secondary Structure
MYVDSHCHLDFPDLIAREDEVLAAMAANDVRHALCVSVKLEDFPRVLGVAERHPGLWASV
CCCCCCCCCCCHHHHHCCHHHHHHHHHHHHHEEHEEEEEHHHHHHHHHHHHCCCCCEEEE
GVHPDNADCEEPDVARLTALAAHPRVVAIGETGLDYYWHKDAPEWQRARFRTHIRAARAC
CCCCCCCCCCCCCHHHHHHHHCCCEEEEECCCCCCEEECCCCCHHHHHHHHHHHHHHHHC
GKPLIVHTRNAAADTLRLMNEEDAGAAGGVMHCFTETREVAEAALDLGFYISFSGIVTFR
CCCEEEEECCCHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHEEEEEEEEEEH
NAAALKEVATLVPLDRLLIETDSPYLAPVPHRGHTNEPAWVVHVAEEIARLRGEPLSRIA
HHHHHHHHHHHHHHHHHEEECCCCCCCCCCCCCCCCCCEEEEHHHHHHHHHCCCHHHHHH
EATTDNFFRLFSHAHP
HHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]