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The map label for this gene is hlyB [H]

Identifier: 119897748

GI number: 119897748

Start: 1589532

End: 1591208

Strand: Direct

Name: hlyB [H]

Synonym: azo1457

Alternate gene names: 119897748

Gene position: 1589532-1591208 (Clockwise)

Preceding gene: 119897747

Following gene: 119897749

Centisome position: 36.32

GC content: 68.34

Gene sequence:

>1677_bases
ATGGGTTTGGCTTTGATTGCGGTGGTGGCGGGCGTCGCGTCTGCCGTGGGCGGCACGGCCGCGGTTGCGGTGGGCGGCGG
ACTGACGCCGCTCGCGGCGGCGGGGCAGGTGCTGGTGGGCGTGATCGTGGCGGCGGTGACCTGGGGCCTGCTGCGGGCGC
AGGTGGGTAGCGGTCTGGCGGCTTTTGCCGAGACCTTGCGCCAGATGCACCGCGACGGCGACCTGTCGCGACGCGCAAAG
GTGGGCGCCGGGCCGGTGGCGCCGTGCGCTGACACCTTCAATCTACTGATCGAGAGCTTCCAGGGCATCGTCGGCAAGGT
GATCTACGACGCCCAGCGCGTCGCCTCCACGGCCGACGTGCTGTCGCGCCATGCGCGCAGCGTTGCCGACGGCTCCAGCG
CGCAGCGCGACGCCTCCGAGCAGATGGTGCGCGCGATCGAGGAAATGACCGCCGGCGTGAATGCGGTCGCCGATCATGCG
ACGCTGACCGCGCACAACGCGCAGGAAGCGCGCGAACTCTCCCGCGAGGGCACCCGCATCGTGTCCGACGCCTCCAAGGA
GATCGAGCGCATCGCGCGCTCGGTCGAGCAGTCGGCCCAGGTGATCGCCGCGCTGGGCGAGCGTTCGGAAGCGATCAGCG
GCATCGTCAAGGTGATCCGCGAGATCGCCGACCAGACCAACCTGCTGGCGCTCAATGCGGCGATCGAGGCCGCGCGCGCG
GGCGAGCAGGGCCGCGGCTTCGCGGTGGTGGCGGACGAGGTGCGCAAGCTGGCCGAGCGGACCTCCGCGGCGACCAGCGA
GATCGGCACGATGATCAATGCGATCCAGGACGAGACCCGCACGGCGATTTCGTCGATCCGCGAAGGCAGCAACCAGGCCC
ACGCCGGCGCGCAACTCGCGCAGCAGGCGGCCGGTTCGCTCGAACGTATCAACCAGGGTGCGCAGCAGACGATGGAGCGC
ATCGACGAGATCGCGGTGGCGATCGCGCAGCAGAGCCGCGAGGCGGACAGCGTCGTCGGCCATGTGCGCCACATCATGGA
CATGGTAGAGCGCAACTCCACCGGCGCCGCCGATACGCTGCAGGAAGCGCAGTCGCTGGAGAGCCTGGCGGCCAACCTGC
ACGAGATCAGCAAGGTCTTCCGCCTCGGCTCGGAGGGCGAGCAGGCGATGCAGGTGCACAAGCGCATGCCGGAGATCGTC
CAGCAGGCCGCGCGCGAGGTCGGCAAGCTGCTGGAAGACGCGATCGCGGCGGGTCAGCTGACCGAGGAGGCCGCGTTCGA
CTCCAATTACCAGCCGATTCCCAACACCCGGCCGCAGAAGTTCAATACGCGCTTCGACAGCCTCACCGACAAGGTCTTCC
CGCGTGTGCAGGAAGCCGTGCTCGACCGCAACGCCGAGGCGGTGTATGCGATCGGCTGCGACCGCAAGGGCTATGTGCCG
ACGCACAACAAGCGCTTTTCGCAGCCGCTCACCGGCGACTACGACAAGGACTTCGTCGGCAACCGCAGCAAGCGCGTCTT
CGACGACCCGGTGGGCAAACAGTGCGGCGCGCACGAACTGGAGTTCCTGATCCAGACCTATCGCCGCGACACCGGTGAAA
TCATGCACGACATCTCCGCCCCGGTTTACGTGAAGGGCCGCCACTGGGGCGGTTTCCGTATCGGCTACAAGGCATAG

Upstream 100 bases:

>100_bases
GCGTCGCCGATAGAATCCGGCACGGAGACGGATTGCCGCCCGGCAGTCCGGGAGAAGCGATAAAAACGCGGCGACGACCG
CGAGACCGGGGGAAGTAGAC

Downstream 100 bases:

>100_bases
ACGGCCGCCGAACGGGGCAGGGCGAGGCGCCGTCAAAATCCGGCACGGTGCCGCGCCGCGAGGCATGGTTGATGCGAGAA
TGCGGAGCCGCTCCGGTCCT

Product: methyl accepting chemotaxis protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 558; Mature: 557

Protein sequence:

>558_residues
MGLALIAVVAGVASAVGGTAAVAVGGGLTPLAAAGQVLVGVIVAAVTWGLLRAQVGSGLAAFAETLRQMHRDGDLSRRAK
VGAGPVAPCADTFNLLIESFQGIVGKVIYDAQRVASTADVLSRHARSVADGSSAQRDASEQMVRAIEEMTAGVNAVADHA
TLTAHNAQEARELSREGTRIVSDASKEIERIARSVEQSAQVIAALGERSEAISGIVKVIREIADQTNLLALNAAIEAARA
GEQGRGFAVVADEVRKLAERTSAATSEIGTMINAIQDETRTAISSIREGSNQAHAGAQLAQQAAGSLERINQGAQQTMER
IDEIAVAIAQQSREADSVVGHVRHIMDMVERNSTGAADTLQEAQSLESLAANLHEISKVFRLGSEGEQAMQVHKRMPEIV
QQAAREVGKLLEDAIAAGQLTEEAAFDSNYQPIPNTRPQKFNTRFDSLTDKVFPRVQEAVLDRNAEAVYAIGCDRKGYVP
THNKRFSQPLTGDYDKDFVGNRSKRVFDDPVGKQCGAHELEFLIQTYRRDTGEIMHDISAPVYVKGRHWGGFRIGYKA

Sequences:

>Translated_558_residues
MGLALIAVVAGVASAVGGTAAVAVGGGLTPLAAAGQVLVGVIVAAVTWGLLRAQVGSGLAAFAETLRQMHRDGDLSRRAK
VGAGPVAPCADTFNLLIESFQGIVGKVIYDAQRVASTADVLSRHARSVADGSSAQRDASEQMVRAIEEMTAGVNAVADHA
TLTAHNAQEARELSREGTRIVSDASKEIERIARSVEQSAQVIAALGERSEAISGIVKVIREIADQTNLLALNAAIEAARA
GEQGRGFAVVADEVRKLAERTSAATSEIGTMINAIQDETRTAISSIREGSNQAHAGAQLAQQAAGSLERINQGAQQTMER
IDEIAVAIAQQSREADSVVGHVRHIMDMVERNSTGAADTLQEAQSLESLAANLHEISKVFRLGSEGEQAMQVHKRMPEIV
QQAAREVGKLLEDAIAAGQLTEEAAFDSNYQPIPNTRPQKFNTRFDSLTDKVFPRVQEAVLDRNAEAVYAIGCDRKGYVP
THNKRFSQPLTGDYDKDFVGNRSKRVFDDPVGKQCGAHELEFLIQTYRRDTGEIMHDISAPVYVKGRHWGGFRIGYKA
>Mature_557_residues
GLALIAVVAGVASAVGGTAAVAVGGGLTPLAAAGQVLVGVIVAAVTWGLLRAQVGSGLAAFAETLRQMHRDGDLSRRAKV
GAGPVAPCADTFNLLIESFQGIVGKVIYDAQRVASTADVLSRHARSVADGSSAQRDASEQMVRAIEEMTAGVNAVADHAT
LTAHNAQEARELSREGTRIVSDASKEIERIARSVEQSAQVIAALGERSEAISGIVKVIREIADQTNLLALNAAIEAARAG
EQGRGFAVVADEVRKLAERTSAATSEIGTMINAIQDETRTAISSIREGSNQAHAGAQLAQQAAGSLERINQGAQQTMERI
DEIAVAIAQQSREADSVVGHVRHIMDMVERNSTGAADTLQEAQSLESLAANLHEISKVFRLGSEGEQAMQVHKRMPEIVQ
QAAREVGKLLEDAIAAGQLTEEAAFDSNYQPIPNTRPQKFNTRFDSLTDKVFPRVQEAVLDRNAEAVYAIGCDRKGYVPT
HNKRFSQPLTGDYDKDFVGNRSKRVFDDPVGKQCGAHELEFLIQTYRRDTGEIMHDISAPVYVKGRHWGGFRIGYKA

Specific function: May form a pore through which the hemolysin can be exported [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell outer membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI2367378, Length=367, Percent_Identity=28.3378746594005, Blast_Score=103, Evalue=3e-23,
Organism=Escherichia coli, GI1787690, Length=352, Percent_Identity=30.9659090909091, Blast_Score=102, Evalue=5e-23,
Organism=Escherichia coli, GI1788195, Length=244, Percent_Identity=33.1967213114754, Blast_Score=98, Evalue=1e-21,
Organism=Escherichia coli, GI1789453, Length=279, Percent_Identity=29.7491039426523, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI1788194, Length=319, Percent_Identity=31.3479623824451, Blast_Score=91, Evalue=3e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660
- InterPro:   IPR000727 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 59603; Mature: 59472

Theoretical pI: Translated: 6.08; Mature: 6.08

Prosite motif: PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGLALIAVVAGVASAVGGTAAVAVGGGLTPLAAAGQVLVGVIVAAVTWGLLRAQVGSGLA
CHHHHHHHHHHHHHHHCCHHHEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHH
AFAETLRQMHRDGDLSRRAKVGAGPVAPCADTFNLLIESFQGIVGKVIYDAQRVASTADV
HHHHHHHHHHCCCCHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LSRHARSVADGSSAQRDASEQMVRAIEEMTAGVNAVADHATLTAHNAQEARELSREGTRI
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCHHH
VSDASKEIERIARSVEQSAQVIAALGERSEAISGIVKVIREIADQTNLLALNAAIEAARA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEHHHHHHHHHHC
GEQGRGFAVVADEVRKLAERTSAATSEIGTMINAIQDETRTAISSIREGSNQAHAGAQLA
CCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
QQAAGSLERINQGAQQTMERIDEIAVAIAQQSREADSVVGHVRHIMDMVERNSTGAADTL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHH
QEAQSLESLAANLHEISKVFRLGSEGEQAMQVHKRMPEIVQQAAREVGKLLEDAIAAGQL
HHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TEEAAFDSNYQPIPNTRPQKFNTRFDSLTDKVFPRVQEAVLDRNAEAVYAIGCDRKGYVP
HHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCC
THNKRFSQPLTGDYDKDFVGNRSKRVFDDPVGKQCGAHELEFLIQTYRRDTGEIMHDISA
CCCCCCCCCCCCCCCCHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCC
PVYVKGRHWGGFRIGYKA
CEEEECCCCCCEECCCCC
>Mature Secondary Structure 
GLALIAVVAGVASAVGGTAAVAVGGGLTPLAAAGQVLVGVIVAAVTWGLLRAQVGSGLA
HHHHHHHHHHHHHHHCCHHHEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHH
AFAETLRQMHRDGDLSRRAKVGAGPVAPCADTFNLLIESFQGIVGKVIYDAQRVASTADV
HHHHHHHHHHCCCCHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LSRHARSVADGSSAQRDASEQMVRAIEEMTAGVNAVADHATLTAHNAQEARELSREGTRI
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCHHH
VSDASKEIERIARSVEQSAQVIAALGERSEAISGIVKVIREIADQTNLLALNAAIEAARA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEHHHHHHHHHHC
GEQGRGFAVVADEVRKLAERTSAATSEIGTMINAIQDETRTAISSIREGSNQAHAGAQLA
CCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
QQAAGSLERINQGAQQTMERIDEIAVAIAQQSREADSVVGHVRHIMDMVERNSTGAADTL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHH
QEAQSLESLAANLHEISKVFRLGSEGEQAMQVHKRMPEIVQQAAREVGKLLEDAIAAGQL
HHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TEEAAFDSNYQPIPNTRPQKFNTRFDSLTDKVFPRVQEAVLDRNAEAVYAIGCDRKGYVP
HHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCC
THNKRFSQPLTGDYDKDFVGNRSKRVFDDPVGKQCGAHELEFLIQTYRRDTGEIMHDISA
CCCCCCCCCCCCCCCCHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCC
PVYVKGRHWGGFRIGYKA
CEEEECCCCCCEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2162464; 10952301 [H]