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The map label for this gene is htpG [H]

Identifier: 119897716

GI number: 119897716

Start: 1555626

End: 1557557

Strand: Direct

Name: htpG [H]

Synonym: azo1425

Alternate gene names: 119897716

Gene position: 1555626-1557557 (Clockwise)

Preceding gene: 119897715

Following gene: 119897718

Centisome position: 35.55

GC content: 63.41

Gene sequence:

>1932_bases
ATGTCCGAAGCGCAAGCCGCAGCCCAGACCCTCAATTTCCAGGCCGAGGTGAAGCAACTGCTTCACCTGATGATCCACTC
GCTCTATTCCAACCGCGAGATCTTCCTGCGCGAACTGGTCTCGAACGCGTCGGACGCCTGCGACAAGCTGCGTTTCGAAG
CGCTCGACAACGCCGCGCTGTTCGAAGGCGAGGGTGACCTCAAGATCCGCATCGCCTTCGACAAGGACGCCAAGACGATC
ACCATCGCCGACAACGGCATCGGCATGAGCCGCGACGAGGCGATCTCCCACCTCGGCACCATCGCCAAGTCGGGCACCAA
GGAATTCTTCGGCAAGCTCACCGGCGACCAGAAGAAGGACGCCAACCTCATCGGCCAGTTCGGCGTCGGCTTCTACTCCG
CCTTCCTGGTGGCCGACCGCGTTACCGTGCTGACCCGCCGCGCCGGCCTGCCGGCCTCGGCGGGGGTGAAGTGGCAGTGT
TCGATGGCGGGCGACGAAGCCGGCGCCTACACCGTGGAGGACATCGACAAGCCCGGCCGCGGCACCGAAATCACGCTGCA
CCTGCGCGATGGCCAGGAAGACCTGCTGTCGTCGTGGAAGCTGAAGAGCCTGGTGCGCAAGTACTCGGACCACATCGTCC
AGCCCATCGTGATGAAGAAGGAGGAGTGGAACGAGGAGAAGAACGAGCAGGTCGTCACCGACGAGGACGAGACGGTGAAC
CAGGCCAACGCGCTGTGGACCCGCTCGAAGAACGACATCTCGGAAGACGAGTACAAGGCTTTCTACAAGCACGTCGGCCA
CGACTACGACGAGCCGCTGGCCTGGACCCATTCGCGCGTCGAAGGCCGCCACGAATACACCAACCTGCTCTATGTGCCGG
CGCACGCGCCCTTCGACCTGTGGGACCGCAACGCCAAGCACGGCATCAAGCTGTACGTGAAGCGCGTCTTCATCATGGAC
GACGCCGAGAAGCTGATGCCCACCTACCTGCGCTTCGTACGCGGGGTGGTCGATTCCGCCGACCTGCCGCTCAACGTGTC
GCGCGAGATCCTGCAGGAATCCAAGGACATCGACACCATCCGCGCCGGCTGCACGAAGAAGGTGCTCGGCCTGCTGGAAG
ACCTCGCCACCAGCGACGAGGCGGGCGACAAGGAGAAGTACGCCACCTTCTGGAAGGAATTCGGCAAGGTGCTGAAGGAA
GGTGTGGGCGAGGACTTCGCCAACAAGGAGAAGATCGCCGGCCTGCTGCGCTTCGCCTCCACCAAGGCGGACACGCCGGA
CGAGATCGTGTCGCTCAAGGACTACATCGAGCGCATGAAGGAAGGCCAGGACAAGATCTACTTCGTCACCGCCGAAACCT
TCAATGCCGCCAAGAACAGCCCGCACCTCGAGGTCTTCCGCAAGAAGGGCATCGAAGTGCTGCTGCTGTCGGACCGCGTC
GATGAATGGGTGATCGGCAACCTCACCGAGTTCGACGGCAAGCCGCTGGTGTCCGTCGCCAAGGGCGGGCTGGATCTGGG
CGCGCTGGAAGACGAAGCCGAGAAGAAGGAAGCCGAGAAGGCCGCCGACGACTACAAGGACCTGCTGGAGAAGATGAAGG
CCAGCCTCGGCGAGCGCGTGAAGGACGTCAAGGTGACGCTGCGCCTGACCGATTCGCCGGCCTGCCTGGTCGCCGACGAG
CACGACATGGGCATGAACCTGGCGCGCATCCTGAAGGCGGCCGGCCAGAGCGCGCCGGTGTCCAAGCCCATTCTCGAGAT
CAATCCCAACCACCCGGCAGTGCTGCGGCTGAAGTACGAGGAAAAGAGCTTCGACGACTGGGCCGCGGTGCTGTTCGACC
AGGCGCTGCTGGCCGAAGGCGGCACGCTGGACGACCCGGCCACCTTTGTGAAGCGCATCAACCAGCTGATGATGGCGATG
AGCGGCAACTGA

Upstream 100 bases:

>100_bases
ATATCCGCTACGTTTGACCCGGCGCGGCGGCGGGGCTTGAAATCGGCGCGGGCATCCCCACATGGGTGGGCGTCGATTTC
AAAAACACGGAGCCGCATCC

Downstream 100 bases:

>100_bases
GCCGTCGCGTCGTCCGCAGTGCAGAACCGCCCTTCGGGGCGGTTCTGCTTTGTGAAGCGTGCGCGTCGCTCAGCGCGGCT
CGGTGGGTCCGGGCTCCGGC

Product: heat shock protein 90

Products: NA

Alternate protein names: Heat shock protein htpG; High temperature protein G [H]

Number of amino acids: Translated: 643; Mature: 642

Protein sequence:

>643_residues
MSEAQAAAQTLNFQAEVKQLLHLMIHSLYSNREIFLRELVSNASDACDKLRFEALDNAALFEGEGDLKIRIAFDKDAKTI
TIADNGIGMSRDEAISHLGTIAKSGTKEFFGKLTGDQKKDANLIGQFGVGFYSAFLVADRVTVLTRRAGLPASAGVKWQC
SMAGDEAGAYTVEDIDKPGRGTEITLHLRDGQEDLLSSWKLKSLVRKYSDHIVQPIVMKKEEWNEEKNEQVVTDEDETVN
QANALWTRSKNDISEDEYKAFYKHVGHDYDEPLAWTHSRVEGRHEYTNLLYVPAHAPFDLWDRNAKHGIKLYVKRVFIMD
DAEKLMPTYLRFVRGVVDSADLPLNVSREILQESKDIDTIRAGCTKKVLGLLEDLATSDEAGDKEKYATFWKEFGKVLKE
GVGEDFANKEKIAGLLRFASTKADTPDEIVSLKDYIERMKEGQDKIYFVTAETFNAAKNSPHLEVFRKKGIEVLLLSDRV
DEWVIGNLTEFDGKPLVSVAKGGLDLGALEDEAEKKEAEKAADDYKDLLEKMKASLGERVKDVKVTLRLTDSPACLVADE
HDMGMNLARILKAAGQSAPVSKPILEINPNHPAVLRLKYEEKSFDDWAAVLFDQALLAEGGTLDDPATFVKRINQLMMAM
SGN

Sequences:

>Translated_643_residues
MSEAQAAAQTLNFQAEVKQLLHLMIHSLYSNREIFLRELVSNASDACDKLRFEALDNAALFEGEGDLKIRIAFDKDAKTI
TIADNGIGMSRDEAISHLGTIAKSGTKEFFGKLTGDQKKDANLIGQFGVGFYSAFLVADRVTVLTRRAGLPASAGVKWQC
SMAGDEAGAYTVEDIDKPGRGTEITLHLRDGQEDLLSSWKLKSLVRKYSDHIVQPIVMKKEEWNEEKNEQVVTDEDETVN
QANALWTRSKNDISEDEYKAFYKHVGHDYDEPLAWTHSRVEGRHEYTNLLYVPAHAPFDLWDRNAKHGIKLYVKRVFIMD
DAEKLMPTYLRFVRGVVDSADLPLNVSREILQESKDIDTIRAGCTKKVLGLLEDLATSDEAGDKEKYATFWKEFGKVLKE
GVGEDFANKEKIAGLLRFASTKADTPDEIVSLKDYIERMKEGQDKIYFVTAETFNAAKNSPHLEVFRKKGIEVLLLSDRV
DEWVIGNLTEFDGKPLVSVAKGGLDLGALEDEAEKKEAEKAADDYKDLLEKMKASLGERVKDVKVTLRLTDSPACLVADE
HDMGMNLARILKAAGQSAPVSKPILEINPNHPAVLRLKYEEKSFDDWAAVLFDQALLAEGGTLDDPATFVKRINQLMMAM
SGN
>Mature_642_residues
SEAQAAAQTLNFQAEVKQLLHLMIHSLYSNREIFLRELVSNASDACDKLRFEALDNAALFEGEGDLKIRIAFDKDAKTIT
IADNGIGMSRDEAISHLGTIAKSGTKEFFGKLTGDQKKDANLIGQFGVGFYSAFLVADRVTVLTRRAGLPASAGVKWQCS
MAGDEAGAYTVEDIDKPGRGTEITLHLRDGQEDLLSSWKLKSLVRKYSDHIVQPIVMKKEEWNEEKNEQVVTDEDETVNQ
ANALWTRSKNDISEDEYKAFYKHVGHDYDEPLAWTHSRVEGRHEYTNLLYVPAHAPFDLWDRNAKHGIKLYVKRVFIMDD
AEKLMPTYLRFVRGVVDSADLPLNVSREILQESKDIDTIRAGCTKKVLGLLEDLATSDEAGDKEKYATFWKEFGKVLKEG
VGEDFANKEKIAGLLRFASTKADTPDEIVSLKDYIERMKEGQDKIYFVTAETFNAAKNSPHLEVFRKKGIEVLLLSDRVD
EWVIGNLTEFDGKPLVSVAKGGLDLGALEDEAEKKEAEKAADDYKDLLEKMKASLGERVKDVKVTLRLTDSPACLVADEH
DMGMNLARILKAAGQSAPVSKPILEINPNHPAVLRLKYEEKSFDDWAAVLFDQALLAEGGTLDDPATFVKRINQLMMAMS
GN

Specific function: Molecular chaperone. Has ATPase activity [H]

COG id: COG0326

COG function: function code O; Molecular chaperone, HSP90 family

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the heat shock protein 90 family [H]

Homologues:

Organism=Homo sapiens, GI20149594, Length=689, Percent_Identity=40.2031930333817, Blast_Score=449, Evalue=1e-126,
Organism=Homo sapiens, GI4507677, Length=704, Percent_Identity=38.7784090909091, Blast_Score=431, Evalue=1e-120,
Organism=Homo sapiens, GI155722983, Length=654, Percent_Identity=35.3211009174312, Blast_Score=363, Evalue=1e-100,
Organism=Homo sapiens, GI154146191, Length=414, Percent_Identity=43.2367149758454, Blast_Score=305, Evalue=9e-83,
Organism=Homo sapiens, GI153792590, Length=416, Percent_Identity=43.0288461538462, Blast_Score=303, Evalue=4e-82,
Organism=Escherichia coli, GI1786679, Length=635, Percent_Identity=58.740157480315, Blast_Score=766, Evalue=0.0,
Organism=Caenorhabditis elegans, GI17559162, Length=677, Percent_Identity=40.9158050221566, Blast_Score=471, Evalue=1e-133,
Organism=Caenorhabditis elegans, GI17542208, Length=690, Percent_Identity=37.3913043478261, Blast_Score=399, Evalue=1e-111,
Organism=Caenorhabditis elegans, GI115535205, Length=664, Percent_Identity=34.6385542168675, Blast_Score=336, Evalue=2e-92,
Organism=Caenorhabditis elegans, GI115535167, Length=437, Percent_Identity=36.3844393592677, Blast_Score=254, Evalue=7e-68,
Organism=Saccharomyces cerevisiae, GI6325016, Length=690, Percent_Identity=39.4202898550725, Blast_Score=462, Evalue=1e-131,
Organism=Saccharomyces cerevisiae, GI6323840, Length=686, Percent_Identity=39.6501457725948, Blast_Score=462, Evalue=1e-130,
Organism=Drosophila melanogaster, GI17647529, Length=691, Percent_Identity=40.520984081042, Blast_Score=477, Evalue=1e-135,
Organism=Drosophila melanogaster, GI21357739, Length=705, Percent_Identity=38.2978723404255, Blast_Score=408, Evalue=1e-114,
Organism=Drosophila melanogaster, GI24586016, Length=656, Percent_Identity=33.8414634146341, Blast_Score=350, Evalue=2e-96,

Paralogues:

None

Copy number: 640 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 2419 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR019805
- InterPro:   IPR001404
- InterPro:   IPR020575
- InterPro:   IPR020568 [H]

Pfam domain/function: PF02518 HATPase_c; PF00183 HSP90 [H]

EC number: NA

Molecular weight: Translated: 71853; Mature: 71722

Theoretical pI: Translated: 4.95; Mature: 4.95

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEAQAAAQTLNFQAEVKQLLHLMIHSLYSNREIFLRELVSNASDACDKLRFEALDNAAL
CCHHHHHHHHHCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEE
FEGEGDLKIRIAFDKDAKTITIADNGIGMSRDEAISHLGTIAKSGTKEFFGKLTGDQKKD
EECCCCEEEEEEECCCCCEEEEECCCCCCCHHHHHHHHHHHHHCCHHHHHHHCCCCCCCC
ANLIGQFGVGFYSAFLVADRVTVLTRRAGLPASAGVKWQCSMAGDEAGAYTVEDIDKPGR
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCCCCEEHHHCCCCCC
GTEITLHLRDGQEDLLSSWKLKSLVRKYSDHIVQPIVMKKEEWNEEKNEQVVTDEDETVN
CCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHCCCCCCCCCCCCCHHHHH
QANALWTRSKNDISEDEYKAFYKHVGHDYDEPLAWTHSRVEGRHEYTNLLYVPAHAPFDL
HHHHHHCCCCCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHCCCCCCCCEEEECCCCCHHH
WDRNAKHGIKLYVKRVFIMDDAEKLMPTYLRFVRGVVDSADLPLNVSREILQESKDIDTI
HCCCCCCCHHHHHHHHHEECCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCHHHH
RAGCTKKVLGLLEDLATSDEAGDKEKYATFWKEFGKVLKEGVGEDFANKEKIAGLLRFAS
HHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHH
TKADTPDEIVSLKDYIERMKEGQDKIYFVTAETFNAAKNSPHLEVFRKKGIEVLLLSDRV
CCCCCHHHHHHHHHHHHHHHCCCCEEEEEEECCHHCCCCCCHHHHHHHCCCEEEEECCCC
DEWVIGNLTEFDGKPLVSVAKGGLDLGALEDEAEKKEAEKAADDYKDLLEKMKASLGERV
CHHHCCCCHHCCCCCHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KDVKVTLRLTDSPACLVADEHDMGMNLARILKAAGQSAPVSKPILEINPNHPAVLRLKYE
EEEEEEEEEECCCEEEEECCCCCCCHHHHHHHHCCCCCCCCCCEEEECCCCCEEEEEEEC
EKSFDDWAAVLFDQALLAEGGTLDDPATFVKRINQLMMAMSGN
CCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SEAQAAAQTLNFQAEVKQLLHLMIHSLYSNREIFLRELVSNASDACDKLRFEALDNAAL
CHHHHHHHHHCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEE
FEGEGDLKIRIAFDKDAKTITIADNGIGMSRDEAISHLGTIAKSGTKEFFGKLTGDQKKD
EECCCCEEEEEEECCCCCEEEEECCCCCCCHHHHHHHHHHHHHCCHHHHHHHCCCCCCCC
ANLIGQFGVGFYSAFLVADRVTVLTRRAGLPASAGVKWQCSMAGDEAGAYTVEDIDKPGR
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCCCCEEHHHCCCCCC
GTEITLHLRDGQEDLLSSWKLKSLVRKYSDHIVQPIVMKKEEWNEEKNEQVVTDEDETVN
CCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHCCCCCCCCCCCCCHHHHH
QANALWTRSKNDISEDEYKAFYKHVGHDYDEPLAWTHSRVEGRHEYTNLLYVPAHAPFDL
HHHHHHCCCCCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHCCCCCCCCEEEECCCCCHHH
WDRNAKHGIKLYVKRVFIMDDAEKLMPTYLRFVRGVVDSADLPLNVSREILQESKDIDTI
HCCCCCCCHHHHHHHHHEECCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCHHHH
RAGCTKKVLGLLEDLATSDEAGDKEKYATFWKEFGKVLKEGVGEDFANKEKIAGLLRFAS
HHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHH
TKADTPDEIVSLKDYIERMKEGQDKIYFVTAETFNAAKNSPHLEVFRKKGIEVLLLSDRV
CCCCCHHHHHHHHHHHHHHHCCCCEEEEEEECCHHCCCCCCHHHHHHHCCCEEEEECCCC
DEWVIGNLTEFDGKPLVSVAKGGLDLGALEDEAEKKEAEKAADDYKDLLEKMKASLGERV
CHHHCCCCHHCCCCCHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KDVKVTLRLTDSPACLVADEHDMGMNLARILKAAGQSAPVSKPILEINPNHPAVLRLKYE
EEEEEEEEEECCCEEEEECCCCCCCHHHHHHHHCCCCCCCCCCEEEECCCCCEEEEEEEC
EKSFDDWAAVLFDQALLAEGGTLDDPATFVKRINQLMMAMSGN
CCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA