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The map label for this gene is mltF [H]

Identifier: 119897619

GI number: 119897619

Start: 1445591

End: 1446979

Strand: Direct

Name: mltF [H]

Synonym: azo1328

Alternate gene names: 119897619

Gene position: 1445591-1446979 (Clockwise)

Preceding gene: 119897617

Following gene: 119897628

Centisome position: 33.03

GC content: 69.83

Gene sequence:

>1389_bases
TTGCGCCTCTTCTTCTGCCTGTTCTTCGCATTATTGCTGTCCGCCTGCGGTCGCGAGGCGCCGACGCGCATTGCCGACTT
CCGGACGCTGGGCGAACTGCGGGTGGCGACGCGGCTGGACGCGATTTCCTACCGCGAGGAGGGGGACGGCGCCACCTCCG
GGTTCGAACACGACCTGCTCGTGCAATTGGGCCAGGCGCTGGAGGTGCCGGTCCGCTTCGTGGTGTATCCGGACAGCGTG
CGTGCGCTGGACGCGGTGATCAAGGGTGAGGCGCATCTTGCCGCGGCGGGGTTGGCGCGCAACGACCGCCTGCCGCTGGC
GTGGTCCGCGCCCTTGCGCGAGGTGGATTTCGTGCTGGCGGGGCGCAGCGACGGGGGCGATATCGGGCGCGAGGCGGACC
TTGCCGGCCGCACGGTGACGGTGCGGCGCGGCTCGCTGGCGGCAGAGGCGTTGGAGCAGATCCGGCGCCGCGTGCCGAGC
TTGCGCGTGAACTATGCGCAGCGCGCGGAGGACTCGGCGATGCTGGAGCAACTCGCGGCGGGTCAGGCCGATCTGGTGGC
CACCGACCGGGTGCATTACGCGCTGGCGGCGCAGATCCATCCCGAACTGAACATCGCTTACGACCTGCCGGTTAAATCCC
ATGTGGCGTGGGCGCTGCCGCGCGAGCAGGGCGGCGCGCTGGGCAAGGCGGTGGCGGAGTTCCTGGATGGCGCGCAGGGC
AATGGGTTGATCGCGCGTAGCGCGGACCGCTACTTCGGCTATGTGCGCCGCCTGACCGACGTCGATATCGAAACCTTCCT
CGGCCGCATCCGCGAACGGCTGCCGCAGTTCCGCCCGCATTTCCACGAAGCGCAGGCCCGCACCGGCATCGACTGGCGCT
ACCTGGCGGCGCTGTCGTACCAGGAGTCGCACTGGGACCCGCTGGCGACCTCGCGTACCGGCGTGCGCGGCATCATGATG
CTGACCGCCGATACCGCGGATCGGCTGGGGGTGGCGGACAGGCTGGACCCGCGCCAGAGCATTCTCGGCGGCGCGCGCTA
CCTCTCGATGATCCGCGAGCAGTTGCCGGACGAGATCGAGGAGCCGGACCGCTCGTGGATGGCGACCGCGGCCTACAACC
TGGGCATGGGCCACATGAACGGCGCGCGCGCCATCGCGCGTACGCTGGGCAAGGACGATGCGTCGTGGTGGGAGATGAAG
TCGGTGCTGCCGCTGCTGTCGCGCCAGGACTACGCCGCGCGGCTGAAGGCCGGCCCGGCGCGCGGCGGCGAGGCGGTGAT
CATGACCGAGAACATCCGCAACTATCACGACATCCTGATGCGCATCGAAGCGCCGTTCGACCCGCGCAAGGCGGTGCCCA
AGCTGCGCCTGACCGCGGGCGACCTCTAG

Upstream 100 bases:

>100_bases
GGTTGACGGGGCCGGGCGGCACGGAAATCGGCGCAGGATTTGCCGGAAATCGGCGGGCTGAAGCAGAATCTGCGTCCCCG
AGACTGCCCGAGCCTGCGTT

Downstream 100 bases:

>100_bases
CGCCCGGCGCGGGCAGCGTCGCGCTGCTCAAGCCGGCGGCTGGCGCGTGACAGCGCGAAGCAGCCGGTCCAGTAGATCGC
GCCGATGAAGACATAGCCTT

Product: hypothetical protein

Products: NA

Alternate protein names: Murein lyase F [H]

Number of amino acids: Translated: 462; Mature: 462

Protein sequence:

>462_residues
MRLFFCLFFALLLSACGREAPTRIADFRTLGELRVATRLDAISYREEGDGATSGFEHDLLVQLGQALEVPVRFVVYPDSV
RALDAVIKGEAHLAAAGLARNDRLPLAWSAPLREVDFVLAGRSDGGDIGREADLAGRTVTVRRGSLAAEALEQIRRRVPS
LRVNYAQRAEDSAMLEQLAAGQADLVATDRVHYALAAQIHPELNIAYDLPVKSHVAWALPREQGGALGKAVAEFLDGAQG
NGLIARSADRYFGYVRRLTDVDIETFLGRIRERLPQFRPHFHEAQARTGIDWRYLAALSYQESHWDPLATSRTGVRGIMM
LTADTADRLGVADRLDPRQSILGGARYLSMIREQLPDEIEEPDRSWMATAAYNLGMGHMNGARAIARTLGKDDASWWEMK
SVLPLLSRQDYAARLKAGPARGGEAVIMTENIRNYHDILMRIEAPFDPRKAVPKLRLTAGDL

Sequences:

>Translated_462_residues
MRLFFCLFFALLLSACGREAPTRIADFRTLGELRVATRLDAISYREEGDGATSGFEHDLLVQLGQALEVPVRFVVYPDSV
RALDAVIKGEAHLAAAGLARNDRLPLAWSAPLREVDFVLAGRSDGGDIGREADLAGRTVTVRRGSLAAEALEQIRRRVPS
LRVNYAQRAEDSAMLEQLAAGQADLVATDRVHYALAAQIHPELNIAYDLPVKSHVAWALPREQGGALGKAVAEFLDGAQG
NGLIARSADRYFGYVRRLTDVDIETFLGRIRERLPQFRPHFHEAQARTGIDWRYLAALSYQESHWDPLATSRTGVRGIMM
LTADTADRLGVADRLDPRQSILGGARYLSMIREQLPDEIEEPDRSWMATAAYNLGMGHMNGARAIARTLGKDDASWWEMK
SVLPLLSRQDYAARLKAGPARGGEAVIMTENIRNYHDILMRIEAPFDPRKAVPKLRLTAGDL
>Mature_462_residues
MRLFFCLFFALLLSACGREAPTRIADFRTLGELRVATRLDAISYREEGDGATSGFEHDLLVQLGQALEVPVRFVVYPDSV
RALDAVIKGEAHLAAAGLARNDRLPLAWSAPLREVDFVLAGRSDGGDIGREADLAGRTVTVRRGSLAAEALEQIRRRVPS
LRVNYAQRAEDSAMLEQLAAGQADLVATDRVHYALAAQIHPELNIAYDLPVKSHVAWALPREQGGALGKAVAEFLDGAQG
NGLIARSADRYFGYVRRLTDVDIETFLGRIRERLPQFRPHFHEAQARTGIDWRYLAALSYQESHWDPLATSRTGVRGIMM
LTADTADRLGVADRLDPRQSILGGARYLSMIREQLPDEIEEPDRSWMATAAYNLGMGHMNGARAIARTLGKDDASWWEMK
SVLPLLSRQDYAARLKAGPARGGEAVIMTENIRNYHDILMRIEAPFDPRKAVPKLRLTAGDL

Specific function: Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the

COG id: COG4623

COG function: function code M; Predicted soluble lytic transglycosylase fused to an ABC-type amino acid-binding protein

Gene ontology:

Cell location: Cell outer membrane; Peripheral membrane protein. Note=Attached to the inner leaflet of the outer membrane [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the transglycosylase slt family [H]

Homologues:

Organism=Escherichia coli, GI171474010, Length=427, Percent_Identity=36.5339578454333, Blast_Score=242, Evalue=4e-65,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008258
- InterPro:   IPR001638 [H]

Pfam domain/function: PF00497 SBP_bac_3; PF01464 SLT [H]

EC number: NA

Molecular weight: Translated: 51134; Mature: 51134

Theoretical pI: Translated: 7.08; Mature: 7.08

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS00922 TRANSGLYCOSYLASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLFFCLFFALLLSACGREAPTRIADFRTLGELRVATRLDAISYREEGDGATSGFEHDLL
CHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHH
VQLGQALEVPVRFVVYPDSVRALDAVIKGEAHLAAAGLARNDRLPLAWSAPLREVDFVLA
HHHHHHHCCCEEEEEECCHHHHHHHHHCCCCHHHHHCCCCCCCCCEEECCCHHHEEEEEE
GRSDGGDIGREADLAGRTVTVRRGSLAAEALEQIRRRVPSLRVNYAQRAEDSAMLEQLAA
CCCCCCCCCCCCCCCCCEEEEECCCHHHHHHHHHHHHCCCCEECHHHHCHHHHHHHHHHC
GQADLVATDRVHYALAAQIHPELNIAYDLPVKSHVAWALPREQGGALGKAVAEFLDGAQG
CCCCEEEECHHHEEEEEEECCCEEEEEECCCHHHHEEECCHHCCCHHHHHHHHHHCCCCC
NGLIARSADRYFGYVRRLTDVDIETFLGRIRERLPQFRPHFHEAQARTGIDWRYLAALSY
CCEEEECHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCHHHHHHCCCCCCHHHEEECC
QESHWDPLATSRTGVRGIMMLTADTADRLGVADRLDPRQSILGGARYLSMIREQLPDEIE
CCCCCCCCCCCCCCCCEEEEEEECCHHHCCCHHCCCHHHHHHHHHHHHHHHHHHCCHHHC
EPDRSWMATAAYNLGMGHMNGARAIARTLGKDDASWWEMKSVLPLLSRQDYAARLKAGPA
CCCHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCHHHHHCCCCC
RGGEAVIMTENIRNYHDILMRIEAPFDPRKAVPKLRLTAGDL
CCCCEEEEECCCCCHHHHHEEECCCCCHHHCCCCEEECCCCC
>Mature Secondary Structure
MRLFFCLFFALLLSACGREAPTRIADFRTLGELRVATRLDAISYREEGDGATSGFEHDLL
CHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHH
VQLGQALEVPVRFVVYPDSVRALDAVIKGEAHLAAAGLARNDRLPLAWSAPLREVDFVLA
HHHHHHHCCCEEEEEECCHHHHHHHHHCCCCHHHHHCCCCCCCCCEEECCCHHHEEEEEE
GRSDGGDIGREADLAGRTVTVRRGSLAAEALEQIRRRVPSLRVNYAQRAEDSAMLEQLAA
CCCCCCCCCCCCCCCCCEEEEECCCHHHHHHHHHHHHCCCCEECHHHHCHHHHHHHHHHC
GQADLVATDRVHYALAAQIHPELNIAYDLPVKSHVAWALPREQGGALGKAVAEFLDGAQG
CCCCEEEECHHHEEEEEEECCCEEEEEECCCHHHHEEECCHHCCCHHHHHHHHHHCCCCC
NGLIARSADRYFGYVRRLTDVDIETFLGRIRERLPQFRPHFHEAQARTGIDWRYLAALSY
CCEEEECHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCHHHHHHCCCCCCHHHEEECC
QESHWDPLATSRTGVRGIMMLTADTADRLGVADRLDPRQSILGGARYLSMIREQLPDEIE
CCCCCCCCCCCCCCCCEEEEEEECCHHHCCCHHCCCHHHHHHHHHHHHHHHHHHCCHHHC
EPDRSWMATAAYNLGMGHMNGARAIARTLGKDDASWWEMKSVLPLLSRQDYAARLKAGPA
CCCHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCHHHHHCCCCC
RGGEAVIMTENIRNYHDILMRIEAPFDPRKAVPKLRLTAGDL
CCCCEEEEECCCCCHHHHHEEECCCCCHHHCCCCEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA