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The map label for this gene is algR [H]

Identifier: 119897282

GI number: 119897282

Start: 1063863

End: 1064624

Strand: Direct

Name: algR [H]

Synonym: azo0991

Alternate gene names: 119897282

Gene position: 1063863-1064624 (Clockwise)

Preceding gene: 119897281

Following gene: 119897284

Centisome position: 24.31

GC content: 69.16

Gene sequence:

>762_bases
ATGAACGATACCTTGCGGGTTCTCATCGTCGATGACGAAACACCGGCGCGCACGCGCCTGCGCGATCTTCTGGGCGATAT
CGGCGCAACCTGCCCGAACGTGGTCGTCGGCATGGCGGCCAACGGCGTCGAGGCACTGCGTCTGATCGAGCAGGCGGGCG
GCGCCGACGTGGTGTTGTGCGACATCCGCATGCCGGTGATGGACGGCGTGGAACTGGCGCGCCATCTGGGGCGCATGACC
GAGCCGCCCGCGGTGATCTTCACCACCGCGTACGACCAGTACGCCGTGCAGGCTTTCGAACTGGCCGCGGTTGATTACCT
GCTCAAGCCGGTACGGGCTGAGCGCCTGGCGGCCGCGCTCGCCAAGGTGCGCCAGCGCCGCGTACCCACCGACCAGGCCC
TGGCGGCACTGGCGCCCGGCGAACGCCGCCATTTCAGCGTCAACGAGCGCGGCCGCATCCTGCTGCTGCCGGTGGTCGAC
GTGCGCTACCTGAAGGCCGAGCTGAAGTACGTCACGGCCCGCACGATAGAGCGCGAGTTCGTGCTCGACGAGGCGCTGAC
GCAGATCGAGCACGAATTCGGCGAACGCTTCCTGCGCATCCACCGCAATTGCCTCGTGGCGCGCGCCGCTGTTGCGGGGG
TGGAGCGCGCGGGCGAGCAGGACGGCGAGGCGCATTGGGAAATCCTGCTCACCGGCGTTCCCGAGCGCCTGCCGGTGAGC
CGCCGGCAGTGGCCGGCGGTCAAGCAGGCGCTCGGCCTGTAG

Upstream 100 bases:

>100_bases
GGCTGATGCTGTTTTTCGATCTGGAGGCGGGGCTGGACATCGACAGCGACGACGTGCGCTATCGGGTGCGGATCCGTCTG
CCTTACCGTCATGGTGCTAC

Downstream 100 bases:

>100_bases
CGCGTCTCGCCACTACCGGCGCGGGGGCCTCAGCCGCTGTTGCGCAGGCCGGCGGCGATGCCGTTGATGGAGATGTGGAT
GCCGTTGCGGATGCGGGCAT

Product: alginate biosynthesis regulatory protein AlgR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 253; Mature: 253

Protein sequence:

>253_residues
MNDTLRVLIVDDETPARTRLRDLLGDIGATCPNVVVGMAANGVEALRLIEQAGGADVVLCDIRMPVMDGVELARHLGRMT
EPPAVIFTTAYDQYAVQAFELAAVDYLLKPVRAERLAAALAKVRQRRVPTDQALAALAPGERRHFSVNERGRILLLPVVD
VRYLKAELKYVTARTIEREFVLDEALTQIEHEFGERFLRIHRNCLVARAAVAGVERAGEQDGEAHWEILLTGVPERLPVS
RRQWPAVKQALGL

Sequences:

>Translated_253_residues
MNDTLRVLIVDDETPARTRLRDLLGDIGATCPNVVVGMAANGVEALRLIEQAGGADVVLCDIRMPVMDGVELARHLGRMT
EPPAVIFTTAYDQYAVQAFELAAVDYLLKPVRAERLAAALAKVRQRRVPTDQALAALAPGERRHFSVNERGRILLLPVVD
VRYLKAELKYVTARTIEREFVLDEALTQIEHEFGERFLRIHRNCLVARAAVAGVERAGEQDGEAHWEILLTGVPERLPVS
RRQWPAVKQALGL
>Mature_253_residues
MNDTLRVLIVDDETPARTRLRDLLGDIGATCPNVVVGMAANGVEALRLIEQAGGADVVLCDIRMPVMDGVELARHLGRMT
EPPAVIFTTAYDQYAVQAFELAAVDYLLKPVRAERLAAALAKVRQRRVPTDQALAALAPGERRHFSVNERGRILLLPVVD
VRYLKAELKYVTARTIEREFVLDEALTQIEHEFGERFLRIHRNCLVARAAVAGVERAGEQDGEAHWEILLTGVPERLPVS
RRQWPAVKQALGL

Specific function: Positive regulator of the algD gene, which codes for a GDP-mannose dehydrogenase, a key step enzyme in the alginate biosynthesis pathway [H]

COG id: COG3279

COG function: function code KT; Response regulator of the LytR/AlgR family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI87082052, Length=259, Percent_Identity=35.5212355212355, Blast_Score=111, Evalue=5e-26,
Organism=Escherichia coli, GI1788724, Length=252, Percent_Identity=26.984126984127, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI1790437, Length=124, Percent_Identity=35.4838709677419, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR007492
- InterPro:   IPR001789 [H]

Pfam domain/function: PF04397 LytTR; PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 28099; Mature: 28099

Theoretical pI: Translated: 6.68; Mature: 6.68

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS50930 HTH_LYTTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNDTLRVLIVDDETPARTRLRDLLGDIGATCPNVVVGMAANGVEALRLIEQAGGADVVLC
CCCCEEEEEEECCCCHHHHHHHHHHHHCCCCCHHHHHHCCCHHHHHHHHHHCCCCCEEEE
DIRMPVMDGVELARHLGRMTEPPAVIFTTAYDQYAVQAFELAAVDYLLKPVRAERLAAAL
ECCCCHHHHHHHHHHHCCCCCCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AKVRQRRVPTDQALAALAPGERRHFSVNERGRILLLPVVDVRYLKAELKYVTARTIEREF
HHHHHHCCCHHHHHHHCCCCCCCEECCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHH
VLDEALTQIEHEFGERFLRIHRNCLVARAAVAGVERAGEQDGEAHWEILLTGVPERLPVS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEECCCCCCCCC
RRQWPAVKQALGL
CCCCHHHHHHHCC
>Mature Secondary Structure
MNDTLRVLIVDDETPARTRLRDLLGDIGATCPNVVVGMAANGVEALRLIEQAGGADVVLC
CCCCEEEEEEECCCCHHHHHHHHHHHHCCCCCHHHHHHCCCHHHHHHHHHHCCCCCEEEE
DIRMPVMDGVELARHLGRMTEPPAVIFTTAYDQYAVQAFELAAVDYLLKPVRAERLAAAL
ECCCCHHHHHHHHHHHCCCCCCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AKVRQRRVPTDQALAALAPGERRHFSVNERGRILLLPVVDVRYLKAELKYVTARTIEREF
HHHHHHCCCHHHHHHHCCCCCCCEECCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHH
VLDEALTQIEHEFGERFLRIHRNCLVARAAVAGVERAGEQDGEAHWEILLTGVPERLPVS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEECCCCCCCCC
RRQWPAVKQALGL
CCCCHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2493441; 10984043; 2544550; 8159168 [H]