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The map label for this gene is engA

Identifier: 119897222

GI number: 119897222

Start: 997232

End: 998560

Strand: Direct

Name: engA

Synonym: azo0931

Alternate gene names: 119897222

Gene position: 997232-998560 (Clockwise)

Preceding gene: 119897221

Following gene: 119897223

Centisome position: 22.79

GC content: 67.04

Gene sequence:

>1329_bases
GTGAAACCAACGATCGTCCTCGTCGGTCGGCCCAATGTCGGCAAATCGACCCTCTTCAACCGGCTCACCAAGACGCGCGA
CGCGCTCGTTGCCGACCAGCCGGGCCTGACGCGCGATCGCCATTACGGTGTCGGCCGCGTTGGCGACCGTGATTACCTCG
TGGTGGATACCGCCGGTTTCGACCCCGTGGCCAAGGACGGGATCATGCACGAGATGGCGCGGCAGGCCGAACAGGCCATC
GCCGAGGCTGATGTGCTGCTGTTCCTGGTGGATGGCCGCGCGGGGCGTACCCCGCACGACGACCAGATCGCCGCGCACCT
GCGCCGCGCCGGCCGCCCCGTGGTGGTCGTGGTGAACAAGGCGGAAGGGCTGGACCGCGCGACCGTCGCGGCGGATTTCC
ATGCGCTTGGCCTGGGTGCGCCGCTGGCGGTGTCCGCCGCCCACGGCGACGGCGTCAAGGCGCTCGTCGAACTCGTGCTT
GCGCCGTTCCCGGCTGACGACGAGGTCGAAGCCGCCGAAGATGCCGGTCCGCGCGTCGCCATCGTCGGCCGCCCGAATGT
GGGCAAGTCCACCCTGGTGAACACCCTATTGGGCGAAGAGCGTGTGATCGCCTTCGACATGCCCGGTACCACCCGCGATG
CGATCGCGATTCCCTTCGAGCGCGGCGGCAAGCAGTACACGCTGATCGACACCGCCGGTCTGCGGCGCCGCGGCAAGGTG
TTCGAGGCCGTCGAGAAATTCTCGGTGATCAAGACCCTGCAGGCGATCCAGGAAGCCAATGTCGTGGTGCTGGTCCTCGA
CGCGGCTCAGGACATCTCGGACCAGGACGCGCATATCGCAGGCTTCGTGCTCGATACCGGGCGCGCGCTGGTGGTCGCGA
TCAACAAGTGGGATGCGGTCGATGACTATCGCCGCGCGCGTCTCAAGGAGGATATGGCGCGCAAGCTCGCGTTCCTGTCC
TTCGCACGCTTCCATCAGATTTCGGCCCTGCGCGCGGAGGGCATCGCCGCGCTGTTGAAGTCGGTGGACGGGGCTTACGC
GGCCGCGATGTCCAACCTCTCGACACCGCGCCTCACGCGCACCATGCAAGCCGCGGTCGCCAAGCAGGCCCCACCCCGCC
ATGGCAGCGCCCGGCCCAAACTCCGCTACGCTCACCAGGGCGGCATGAACCCGCCCGTCATCGTGATCCACGGCAACGCG
CTCGATCACATTCCCAACTCCTACGTCCGCTTCCTCGAGCGGACCTTCATGGAGGCCTTCAAGTTGCAGGGGACGCCCTT
GCGGATCCAGTTCCGGACCGCGCACAATCCCTATGCGACAAAGGCGTGA

Upstream 100 bases:

>100_bases
CATCGTCGCCGATCTGCGCGGCTATGGACGCGGCTTCGTCGTCCAGACCCGGTCGGGCGACGTAGTGGCCTATGAAGTGC
GTTAAGGCGGATACACCGAA

Downstream 100 bases:

>100_bases
TTGTCGAGGAATATTTCCACACCAGGGATGATTGATGCATTGTCATTGTGGCGGTGCAGCATGAAATCCTATACATTCAT
AAAAACACAACTATAGAGGT

Product: GTP-binding protein EngA

Products: NA

Alternate protein names: GTP-binding protein EngA

Number of amino acids: Translated: 442; Mature: 442

Protein sequence:

>442_residues
MKPTIVLVGRPNVGKSTLFNRLTKTRDALVADQPGLTRDRHYGVGRVGDRDYLVVDTAGFDPVAKDGIMHEMARQAEQAI
AEADVLLFLVDGRAGRTPHDDQIAAHLRRAGRPVVVVVNKAEGLDRATVAADFHALGLGAPLAVSAAHGDGVKALVELVL
APFPADDEVEAAEDAGPRVAIVGRPNVGKSTLVNTLLGEERVIAFDMPGTTRDAIAIPFERGGKQYTLIDTAGLRRRGKV
FEAVEKFSVIKTLQAIQEANVVVLVLDAAQDISDQDAHIAGFVLDTGRALVVAINKWDAVDDYRRARLKEDMARKLAFLS
FARFHQISALRAEGIAALLKSVDGAYAAAMSNLSTPRLTRTMQAAVAKQAPPRHGSARPKLRYAHQGGMNPPVIVIHGNA
LDHIPNSYVRFLERTFMEAFKLQGTPLRIQFRTAHNPYATKA

Sequences:

>Translated_442_residues
MKPTIVLVGRPNVGKSTLFNRLTKTRDALVADQPGLTRDRHYGVGRVGDRDYLVVDTAGFDPVAKDGIMHEMARQAEQAI
AEADVLLFLVDGRAGRTPHDDQIAAHLRRAGRPVVVVVNKAEGLDRATVAADFHALGLGAPLAVSAAHGDGVKALVELVL
APFPADDEVEAAEDAGPRVAIVGRPNVGKSTLVNTLLGEERVIAFDMPGTTRDAIAIPFERGGKQYTLIDTAGLRRRGKV
FEAVEKFSVIKTLQAIQEANVVVLVLDAAQDISDQDAHIAGFVLDTGRALVVAINKWDAVDDYRRARLKEDMARKLAFLS
FARFHQISALRAEGIAALLKSVDGAYAAAMSNLSTPRLTRTMQAAVAKQAPPRHGSARPKLRYAHQGGMNPPVIVIHGNA
LDHIPNSYVRFLERTFMEAFKLQGTPLRIQFRTAHNPYATKA
>Mature_442_residues
MKPTIVLVGRPNVGKSTLFNRLTKTRDALVADQPGLTRDRHYGVGRVGDRDYLVVDTAGFDPVAKDGIMHEMARQAEQAI
AEADVLLFLVDGRAGRTPHDDQIAAHLRRAGRPVVVVVNKAEGLDRATVAADFHALGLGAPLAVSAAHGDGVKALVELVL
APFPADDEVEAAEDAGPRVAIVGRPNVGKSTLVNTLLGEERVIAFDMPGTTRDAIAIPFERGGKQYTLIDTAGLRRRGKV
FEAVEKFSVIKTLQAIQEANVVVLVLDAAQDISDQDAHIAGFVLDTGRALVVAINKWDAVDDYRRARLKEDMARKLAFLS
FARFHQISALRAEGIAALLKSVDGAYAAAMSNLSTPRLTRTMQAAVAKQAPPRHGSARPKLRYAHQGGMNPPVIVIHGNA
LDHIPNSYVRFLERTFMEAFKLQGTPLRIQFRTAHNPYATKA

Specific function: GTPase that plays an essential role in the late steps of ribosome biogenesis

COG id: COG1160

COG function: function code R; Predicted GTPases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 KH-like domain

Homologues:

Organism=Homo sapiens, GI193082991, Length=197, Percent_Identity=28.9340101522843, Blast_Score=66, Evalue=6e-11,
Organism=Homo sapiens, GI193082988, Length=197, Percent_Identity=28.9340101522843, Blast_Score=66, Evalue=7e-11,
Organism=Escherichia coli, GI87082120, Length=468, Percent_Identity=50.8547008547009, Blast_Score=467, Evalue=1e-133,
Organism=Escherichia coli, GI1788919, Length=120, Percent_Identity=34.1666666666667, Blast_Score=73, Evalue=4e-14,
Organism=Escherichia coli, GI2367268, Length=92, Percent_Identity=40.2173913043478, Blast_Score=67, Evalue=3e-12,
Organism=Saccharomyces cerevisiae, GI6323665, Length=185, Percent_Identity=30.8108108108108, Blast_Score=76, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DER_AZOSB (A1K3Z3)

Other databases:

- EMBL:   AM406670
- RefSeq:   YP_932435.1
- ProteinModelPortal:   A1K3Z3
- SMR:   A1K3Z3
- STRING:   A1K3Z3
- GeneID:   4606635
- GenomeReviews:   AM406670_GR
- KEGG:   azo:azo0931
- eggNOG:   COG1160
- HOGENOM:   HBG592135
- OMA:   TRDRTYQ
- PhylomeDB:   A1K3Z3
- ProtClustDB:   PRK00093
- BioCyc:   ASP62928:AZO0931-MONOMER
- GO:   GO:0005622
- HAMAP:   MF_00195
- InterPro:   IPR003593
- InterPro:   IPR016484
- InterPro:   IPR006073
- InterPro:   IPR015946
- InterPro:   IPR002917
- InterPro:   IPR005225
- Gene3D:   G3DSA:3.30.300.20
- PIRSF:   PIRSF006485
- PRINTS:   PR00326
- SMART:   SM00382
- TIGRFAMs:   TIGR03594
- TIGRFAMs:   TIGR00231

Pfam domain/function: PF01926 MMR_HSR1

EC number: NA

Molecular weight: Translated: 47835; Mature: 47835

Theoretical pI: Translated: 9.98; Mature: 9.98

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKPTIVLVGRPNVGKSTLFNRLTKTRDALVADQPGLTRDRHYGVGRVGDRDYLVVDTAGF
CCCEEEEEECCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCEEEEECCCC
DPVAKDGIMHEMARQAEQAIAEADVLLFLVDGRAGRTPHDDQIAAHLRRAGRPVVVVVNK
CCHHHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCCCCCHHHHHHHHHHCCCCEEEEEEC
AEGLDRATVAADFHALGLGAPLAVSAAHGDGVKALVELVLAPFPADDEVEAAEDAGPRVA
CCCCCHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHCCCCCCCCCCHHHCCCCEEE
IVGRPNVGKSTLVNTLLGEERVIAFDMPGTTRDAIAIPFERGGKQYTLIDTAGLRRRGKV
EEECCCCCHHHHHHHHCCCCEEEEEECCCCCCCEEEEECCCCCCEEEEEECCCCCHHHHH
FEAVEKFSVIKTLQAIQEANVVVLVLDAAQDISDQDAHIAGFVLDTGRALVVAINKWDAV
HHHHHHHHHHHHHHHHHHCCEEEEEEECCCCCCCCCCEEEEEEEECCCEEEEEEECCCCH
DDYRRARLKEDMARKLAFLSFARFHQISALRAEGIAALLKSVDGAYAAAMSNLSTPRLTR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCHHHH
TMQAAVAKQAPPRHGSARPKLRYAHQGGMNPPVIVIHGNALDHIPNSYVRFLERTFMEAF
HHHHHHHHCCCCCCCCCCCCEEEHHCCCCCCCEEEEECCHHHHCCHHHHHHHHHHHHHHH
KLQGTPLRIQFRTAHNPYATKA
HCCCCCEEEEEEECCCCCCCCC
>Mature Secondary Structure
MKPTIVLVGRPNVGKSTLFNRLTKTRDALVADQPGLTRDRHYGVGRVGDRDYLVVDTAGF
CCCEEEEEECCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCEEEEECCCC
DPVAKDGIMHEMARQAEQAIAEADVLLFLVDGRAGRTPHDDQIAAHLRRAGRPVVVVVNK
CCHHHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCCCCCHHHHHHHHHHCCCCEEEEEEC
AEGLDRATVAADFHALGLGAPLAVSAAHGDGVKALVELVLAPFPADDEVEAAEDAGPRVA
CCCCCHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHCCCCCCCCCCHHHCCCCEEE
IVGRPNVGKSTLVNTLLGEERVIAFDMPGTTRDAIAIPFERGGKQYTLIDTAGLRRRGKV
EEECCCCCHHHHHHHHCCCCEEEEEECCCCCCCEEEEECCCCCCEEEEEECCCCCHHHHH
FEAVEKFSVIKTLQAIQEANVVVLVLDAAQDISDQDAHIAGFVLDTGRALVVAINKWDAV
HHHHHHHHHHHHHHHHHHCCEEEEEEECCCCCCCCCCEEEEEEEECCCEEEEEEECCCCH
DDYRRARLKEDMARKLAFLSFARFHQISALRAEGIAALLKSVDGAYAAAMSNLSTPRLTR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCHHHH
TMQAAVAKQAPPRHGSARPKLRYAHQGGMNPPVIVIHGNALDHIPNSYVRFLERTFMEAF
HHHHHHHHCCCCCCCCCCCCEEEHHCCCCCCCEEEEECCHHHHCCHHHHHHHHHHHHHHH
KLQGTPLRIQFRTAHNPYATKA
HCCCCCEEEEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA