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The map label for this gene is gmhA

Identifier: 119897161

GI number: 119897161

Start: 931665

End: 932258

Strand: Reverse

Name: gmhA

Synonym: azo0870

Alternate gene names: 119897161

Gene position: 932258-931665 (Counterclockwise)

Preceding gene: 119897162

Following gene: 119897160

Centisome position: 21.3

GC content: 65.49

Gene sequence:

>594_bases
ATGGACCTGATCGACCGCATTTCCCGCCAGTTCGAAGACAGCGCGCAGACGAAGCTCGCCGCCGTCGAGTGGATGGCGGC
ACCGATCGCCCAGGCGGTGGAAATGATGACCGCCAGCCTGATGAACAACGGCAAGATCCTCGCGTGCGGCAATGGCGGAT
CGGCAGCCGACGCGCAGCACTTCGCCGCGGAACTGCTCAACCGCTTCGAGATGGAGCGCCCGCCGCTCGCCGCCGTGGCG
CTGACCACCGACACCTCCACGCTGACCTCGATCGCCAACGACTACGACTTCGTCCAGGTCTTCTCCAAGCAGGTCCGCGC
GCTCGGCCAGCCGGGCGATGTCCTGCTGGCGATTTCCACCAGCGGCAATTCGCCCAACGTCATCGACGCCATCCAGGCCG
CCCATGAGCGCGAAATGCACGTGGTCGCGCTCACCGGCAAGGGTGGCGGCCGCATCGGCGAGATGCTGAGCCCGACCGAC
GTTCATCTCTGCGTGCCGGCAGACCGTACCGCCCGCATCCAGGAGGTTCACCTGCTGACCCTGCACTGCCTGTGCGACGG
AATCGACTGCCTCTTACTAGGAGTGGAAGAATGA

Upstream 100 bases:

>100_bases
CTTGAGTAAGAAGGTGCAACCACCCCGAGCCGACCCTGAGAGCACTCACGCCGCCATGCTAGACTGCAGCCCCTCCCAGA
GCATCGCTTCAGCACGACGA

Downstream 100 bases:

>100_bases
AGACGACGAGCCGAGCCCGGGCGGCTTCCGGCGCCCGCCGCTATCTCCTCGCGGGCCTGATCGCCGCCGCCCTGCCTGCG
CTGCAGGGCTGCTTCCCCGT

Product: phosphoheptose isomerase

Products: NA

Alternate protein names: Sedoheptulose 7-phosphate isomerase

Number of amino acids: Translated: 197; Mature: 197

Protein sequence:

>197_residues
MDLIDRISRQFEDSAQTKLAAVEWMAAPIAQAVEMMTASLMNNGKILACGNGGSAADAQHFAAELLNRFEMERPPLAAVA
LTTDTSTLTSIANDYDFVQVFSKQVRALGQPGDVLLAISTSGNSPNVIDAIQAAHEREMHVVALTGKGGGRIGEMLSPTD
VHLCVPADRTARIQEVHLLTLHCLCDGIDCLLLGVEE

Sequences:

>Translated_197_residues
MDLIDRISRQFEDSAQTKLAAVEWMAAPIAQAVEMMTASLMNNGKILACGNGGSAADAQHFAAELLNRFEMERPPLAAVA
LTTDTSTLTSIANDYDFVQVFSKQVRALGQPGDVLLAISTSGNSPNVIDAIQAAHEREMHVVALTGKGGGRIGEMLSPTD
VHLCVPADRTARIQEVHLLTLHCLCDGIDCLLLGVEE
>Mature_197_residues
MDLIDRISRQFEDSAQTKLAAVEWMAAPIAQAVEMMTASLMNNGKILACGNGGSAADAQHFAAELLNRFEMERPPLAAVA
LTTDTSTLTSIANDYDFVQVFSKQVRALGQPGDVLLAISTSGNSPNVIDAIQAAHEREMHVVALTGKGGGRIGEMLSPTD
VHLCVPADRTARIQEVHLLTLHCLCDGIDCLLLGVEE

Specific function: Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate

COG id: COG0279

COG function: function code G; Phosphoheptose isomerase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 SIS domain

Homologues:

Organism=Escherichia coli, GI1789539, Length=189, Percent_Identity=53.968253968254, Blast_Score=206, Evalue=1e-54,
Organism=Escherichia coli, GI1786416, Length=157, Percent_Identity=47.1337579617834, Blast_Score=140, Evalue=5e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): GMHA_AZOSB (A1K3T2)

Other databases:

- EMBL:   AM406670
- RefSeq:   YP_932374.1
- ProteinModelPortal:   A1K3T2
- SMR:   A1K3T2
- STRING:   A1K3T2
- GeneID:   4606617
- GenomeReviews:   AM406670_GR
- KEGG:   azo:azo0870
- eggNOG:   COG0279
- HOGENOM:   HBG671955
- OMA:   HDREMIV
- PhylomeDB:   A1K3T2
- ProtClustDB:   PRK13936
- BioCyc:   ASP62928:AZO0870-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00067
- InterPro:   IPR020620
- InterPro:   IPR001347

Pfam domain/function: PF01380 SIS

EC number: =5.3.1.28

Molecular weight: Translated: 21027; Mature: 21027

Theoretical pI: Translated: 4.51; Mature: 4.51

Prosite motif: PS51464 SIS

Important sites: BINDING 64-64 BINDING 124-124 BINDING 174-174

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
6.6 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
6.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDLIDRISRQFEDSAQTKLAAVEWMAAPIAQAVEMMTASLMNNGKILACGNGGSAADAQH
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCHHHH
FAAELLNRFEMERPPLAAVALTTDTSTLTSIANDYDFVQVFSKQVRALGQPGDVLLAIST
HHHHHHHHHCCCCCCEEEEEEECCHHHHHHHHCCHHHHHHHHHHHHHCCCCCCEEEEEEC
SGNSPNVIDAIQAAHEREMHVVALTGKGGGRIGEMLSPTDVHLCVPADRTARIQEVHLLT
CCCCCCHHHHHHHHHCCCEEEEEEECCCCCCCCCCCCCCCEEEEECCCCCCHHHHHHHHH
LHCLCDGIDCLLLGVEE
HHHHHCCCEEEEEEECC
>Mature Secondary Structure
MDLIDRISRQFEDSAQTKLAAVEWMAAPIAQAVEMMTASLMNNGKILACGNGGSAADAQH
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCHHHH
FAAELLNRFEMERPPLAAVALTTDTSTLTSIANDYDFVQVFSKQVRALGQPGDVLLAIST
HHHHHHHHHCCCCCCEEEEEEECCHHHHHHHHCCHHHHHHHHHHHHHCCCCCCEEEEEEC
SGNSPNVIDAIQAAHEREMHVVALTGKGGGRIGEMLSPTDVHLCVPADRTARIQEVHLLT
CCCCCCHHHHHHHHHCCCEEEEEEECCCCCCCCCCCCCCCEEEEECCCCCCHHHHHHHHH
LHCLCDGIDCLLLGVEE
HHHHHCCCEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA