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The map label for this gene is kdsC [H]

Identifier: 119897084

GI number: 119897084

Start: 850359

End: 850880

Strand: Reverse

Name: kdsC [H]

Synonym: azo0793

Alternate gene names: 119897084

Gene position: 850880-850359 (Counterclockwise)

Preceding gene: 119897085

Following gene: 119897083

Centisome position: 19.44

GC content: 67.43

Gene sequence:

>522_bases
ATGGCCCAGCCGGAATCCGCCGCAAAAATCCGCCTGATGGGGTTCGATGTCGACGGTGTCCTCACCGACGGCAGCCTGTA
CTTCACCCCCAACGGCGAAGAGATCAAGGTCTTTTCCAGCCTCGACGGACACGGCATCAAGATGCTGCAGCAGGCCGGCA
TCGAGGTTGCGATCATCAGCGGGCGCAGCTCCAGGGCGCTCGCACTGCGCGCAGCCAACCTGGGCATCGGCGAACTGCAC
ATGGGCGTCGAAGACAAACGCGCCTGTCTGGACGACCTTCTCGCGCGCCGCGGCATCGCGCGGGCGGAAGCCGGCTACAT
GGGCGACGACGTGGTCGATCTTCCCATCCTGCGCGCCTGCGGCTTTTCCGCCACGCCGGCCGACGGCCATCCGTTCGTCC
GCGAACACGTCGATTTCGTTGCCAGCCGCGACGGCGGCCGCGGCGCCGTGCGCGAGGTGTGCGACTTCCTGCTGGCGAGC
CGCGGCGTGCTCGACGCAATGCACGCCGCCTACCTCGACTGA

Upstream 100 bases:

>100_bases
TGGAACGCCAGCGCATCAGCCAGTTGCTGGTGCTCGATGCCGCGGGCAAGCTGGCCGGCGCACTCACCACCCACGACCTG
ATGCTCGCGAAGGTAATCTG

Downstream 100 bases:

>100_bases
GCGCCGACGATGCAGGCCGCCTACCGGCTCTATCCCGTGATTGCCCTCGCCCTGCTGGCGGGCGCCTCCGTATGGCTGGA
GCGGGTGTCCCGTAACGACA

Product: phosphatase

Products: NA

Alternate protein names: KDO 8-P phosphatase [H]

Number of amino acids: Translated: 173; Mature: 172

Protein sequence:

>173_residues
MAQPESAAKIRLMGFDVDGVLTDGSLYFTPNGEEIKVFSSLDGHGIKMLQQAGIEVAIISGRSSRALALRAANLGIGELH
MGVEDKRACLDDLLARRGIARAEAGYMGDDVVDLPILRACGFSATPADGHPFVREHVDFVASRDGGRGAVREVCDFLLAS
RGVLDAMHAAYLD

Sequences:

>Translated_173_residues
MAQPESAAKIRLMGFDVDGVLTDGSLYFTPNGEEIKVFSSLDGHGIKMLQQAGIEVAIISGRSSRALALRAANLGIGELH
MGVEDKRACLDDLLARRGIARAEAGYMGDDVVDLPILRACGFSATPADGHPFVREHVDFVASRDGGRGAVREVCDFLLAS
RGVLDAMHAAYLD
>Mature_172_residues
AQPESAAKIRLMGFDVDGVLTDGSLYFTPNGEEIKVFSSLDGHGIKMLQQAGIEVAIISGRSSRALALRAANLGIGELHM
GVEDKRACLDDLLARRGIARAEAGYMGDDVVDLPILRACGFSATPADGHPFVREHVDFVASRDGGRGAVREVCDFLLASR
GVLDAMHAAYLD

Specific function: Catalyzes the hydrolysis of KDO 8-P to KDO and inorganic phosphate [H]

COG id: COG1778

COG function: function code R; Low specificity phosphatase (HAD superfamily)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the kdsC family [H]

Homologues:

Organism=Homo sapiens, GI8923900, Length=153, Percent_Identity=32.0261437908497, Blast_Score=92, Evalue=3e-19,
Organism=Escherichia coli, GI2367202, Length=160, Percent_Identity=46.25, Blast_Score=146, Evalue=1e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023214
- InterPro:   IPR013200
- InterPro:   IPR006549
- InterPro:   IPR010023 [H]

Pfam domain/function: PF08282 Hydrolase_3 [H]

EC number: =3.1.3.45 [H]

Molecular weight: Translated: 18415; Mature: 18284

Theoretical pI: Translated: 5.01; Mature: 5.01

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAQPESAAKIRLMGFDVDGVLTDGSLYFTPNGEEIKVFSSLDGHGIKMLQQAGIEVAIIS
CCCCCCCCEEEEEEECCCCEEECCEEEECCCCCEEEEEECCCCCHHHHHHHCCCEEEEEE
GRSSRALALRAANLGIGELHMGVEDKRACLDDLLARRGIARAEAGYMGDDVVDLPILRAC
CCCCCEEEEEECCCCCCCEECCCCHHHHHHHHHHHHCCCCHHCCCCCCCCCHHHHHHHHC
GFSATPADGHPFVREHVDFVASRDGGRGAVREVCDFLLASRGVLDAMHAAYLD
CCCCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHCC
>Mature Secondary Structure 
AQPESAAKIRLMGFDVDGVLTDGSLYFTPNGEEIKVFSSLDGHGIKMLQQAGIEVAIIS
CCCCCCCEEEEEEECCCCEEECCEEEECCCCCEEEEEECCCCCHHHHHHHCCCEEEEEE
GRSSRALALRAANLGIGELHMGVEDKRACLDDLLARRGIARAEAGYMGDDVVDLPILRAC
CCCCCEEEEEECCCCCCCEECCCCHHHHHHHHHHHHCCCCHHCCCCCCCCCHHHHHHHHC
GFSATPADGHPFVREHVDFVASRDGGRGAVREVCDFLLASRGVLDAMHAAYLD
CCCCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]