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The map label for this gene is FtsY [H]

Identifier: 119897057

GI number: 119897057

Start: 818232

End: 819365

Strand: Direct

Name: FtsY [H]

Synonym: azo0766

Alternate gene names: 119897057

Gene position: 818232-819365 (Clockwise)

Preceding gene: 119897051

Following gene: 119897058

Centisome position: 18.7

GC content: 69.49

Gene sequence:

>1134_bases
ATGTTTGGTTTCTTCAAGAAGTCCGGCAAGCCCGAACCTGCCGGGCGCGATCCGCAGCCCGCGTCGCCGTCTGCGGAGCA
GGCCCCGGCGATCGCTGCCGACGCGCCCGTCGCTGCTCCCGCGCCGATTTCGCCCGTCCCGGCCCAGCCCGTCACTGCGC
CCGCCGAGCCGGCGGCCGCGCCCAAGCTTTCCTGGGGCGAACGCCTCAAGGCCGGCCTGGCGCGCACGCGCCAGCAGCTC
GGCGGGGGGCTGGCCAACCTGTTCGGGCGCCGCAAGATCGACGAGGATCTGCTCGAAGAGCTGGAAACGACCCTGTTGAT
GGCGGACTGCGGTGTCGACGCCACCCAGTATCTGCTCGATGAACTGCGGCTGCGCTGGAAGCGCGACCGGCTGGAAACCG
CCGACCAGTTGCAGGCGGCGCTGGCCGATGCGCTGCACAAGATCATCGCGCCGCTGGAGCAGCCGCTGGACGTGTCCGGT
CACAAGCCCTACATCATCATGATCGCGGGGGTGAACGGCTCGGGCAAGACGACCTCGATCGGCAAACTTGCCAAGTATTT
CCAGGCCCAGGGCAAGAGCGTGCTGCTGGCGGCCGGCGATACCTTCCGCGCCGCCGCGCGCGAGCAGCTGATGACCTGGG
GCGAGCGCAACAACGTCACCGTGATCGCTCAGGACGGCGGCGATGCGGCCGCGGTGATCTTCGATGCGATCAATGCTGCC
CGTGCGCGCGGCATCGACATCGTGCTCGCCGACACCGCGGGCCGGCTGCCCACGCAACTGCACCTGATGGAGGAAATCGC
CAAGGTGCGGCGCGTGATCGCCAAGGCGGATGCCAGCGGCCCGCACGAGGTCGTGCTGGTGCTGGACGCCAACATCGGCC
AGAACGCGCTGGCACAGGTCAAGGCCTTCGATGCCGCGATCGGCGTCACCGGCCTGGTCGTCACCAAGCTCGACGGCACC
GCGAAAGGCGGGGTCGTCGCGGCGATCGCGCGCCAGTGCCCCAAGCCGCTGCGCTTCATTGGCGTGGGCGAGGGCATCGA
CGACCTGCAGCCGTTCAAGGCCCGCGAGTTCATCGATGCCTTGTTCGAGCCGGCCCCCGCGGGGGCGACCAAGCGCGGCG
ACGCCTCGGCATGA

Upstream 100 bases:

>100_bases
CGTGCCTCGCCGGCACCTGGCATCCGGTCGTGGCGGCCGCGTTGCAGCGTGCTGCAAGCCGGGCTGCCGTGTACGAACGC
CCCCTCTGACCCGAGCGCCC

Downstream 100 bases:

>100_bases
TCGCGTTCGAGCAGGTGGCCAAGCGCTACGCCGGCGGCTACACCGCGCTGGCGGGGGTCAGTTTCGAGATCGCGCGTGGC
GAACTGGTGGTGTTGTCGGG

Product: signal recognition particle-docing protein FtsY

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 377; Mature: 377

Protein sequence:

>377_residues
MFGFFKKSGKPEPAGRDPQPASPSAEQAPAIAADAPVAAPAPISPVPAQPVTAPAEPAAAPKLSWGERLKAGLARTRQQL
GGGLANLFGRRKIDEDLLEELETTLLMADCGVDATQYLLDELRLRWKRDRLETADQLQAALADALHKIIAPLEQPLDVSG
HKPYIIMIAGVNGSGKTTSIGKLAKYFQAQGKSVLLAAGDTFRAAAREQLMTWGERNNVTVIAQDGGDAAAVIFDAINAA
RARGIDIVLADTAGRLPTQLHLMEEIAKVRRVIAKADASGPHEVVLVLDANIGQNALAQVKAFDAAIGVTGLVVTKLDGT
AKGGVVAAIARQCPKPLRFIGVGEGIDDLQPFKAREFIDALFEPAPAGATKRGDASA

Sequences:

>Translated_377_residues
MFGFFKKSGKPEPAGRDPQPASPSAEQAPAIAADAPVAAPAPISPVPAQPVTAPAEPAAAPKLSWGERLKAGLARTRQQL
GGGLANLFGRRKIDEDLLEELETTLLMADCGVDATQYLLDELRLRWKRDRLETADQLQAALADALHKIIAPLEQPLDVSG
HKPYIIMIAGVNGSGKTTSIGKLAKYFQAQGKSVLLAAGDTFRAAAREQLMTWGERNNVTVIAQDGGDAAAVIFDAINAA
RARGIDIVLADTAGRLPTQLHLMEEIAKVRRVIAKADASGPHEVVLVLDANIGQNALAQVKAFDAAIGVTGLVVTKLDGT
AKGGVVAAIARQCPKPLRFIGVGEGIDDLQPFKAREFIDALFEPAPAGATKRGDASA
>Mature_377_residues
MFGFFKKSGKPEPAGRDPQPASPSAEQAPAIAADAPVAAPAPISPVPAQPVTAPAEPAAAPKLSWGERLKAGLARTRQQL
GGGLANLFGRRKIDEDLLEELETTLLMADCGVDATQYLLDELRLRWKRDRLETADQLQAALADALHKIIAPLEQPLDVSG
HKPYIIMIAGVNGSGKTTSIGKLAKYFQAQGKSVLLAAGDTFRAAAREQLMTWGERNNVTVIAQDGGDAAAVIFDAINAA
RARGIDIVLADTAGRLPTQLHLMEEIAKVRRVIAKADASGPHEVVLVLDANIGQNALAQVKAFDAAIGVTGLVVTKLDGT
AKGGVVAAIARQCPKPLRFIGVGEGIDDLQPFKAREFIDALFEPAPAGATKRGDASA

Specific function: Functional homolog of SRP receptor. Probably involved in the reception and insertion of a subset of proteins at the cytoplasmic membrane [H]

COG id: COG0552

COG function: function code U; Signal recognition particle GTPase

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GTP-binding SRP family [H]

Homologues:

Organism=Homo sapiens, GI4507215, Length=271, Percent_Identity=33.5793357933579, Blast_Score=139, Evalue=5e-33,
Organism=Homo sapiens, GI226371618, Length=233, Percent_Identity=35.1931330472103, Blast_Score=134, Evalue=2e-31,
Organism=Homo sapiens, GI295424842, Length=331, Percent_Identity=28.7009063444109, Blast_Score=112, Evalue=5e-25,
Organism=Homo sapiens, GI23308697, Length=331, Percent_Identity=28.7009063444109, Blast_Score=112, Evalue=6e-25,
Organism=Homo sapiens, GI89061728, Length=128, Percent_Identity=39.0625, Blast_Score=91, Evalue=1e-18,
Organism=Escherichia coli, GI1789874, Length=316, Percent_Identity=53.7974683544304, Blast_Score=325, Evalue=3e-90,
Organism=Escherichia coli, GI1788963, Length=286, Percent_Identity=33.9160839160839, Blast_Score=141, Evalue=7e-35,
Organism=Caenorhabditis elegans, GI17539958, Length=271, Percent_Identity=29.8892988929889, Blast_Score=130, Evalue=1e-30,
Organism=Caenorhabditis elegans, GI193206261, Length=323, Percent_Identity=28.1733746130031, Blast_Score=103, Evalue=1e-22,
Organism=Saccharomyces cerevisiae, GI6325345, Length=278, Percent_Identity=32.7338129496403, Blast_Score=133, Evalue=5e-32,
Organism=Saccharomyces cerevisiae, GI6320498, Length=231, Percent_Identity=28.1385281385281, Blast_Score=86, Evalue=1e-17,
Organism=Drosophila melanogaster, GI17647949, Length=281, Percent_Identity=32.0284697508897, Blast_Score=140, Evalue=2e-33,
Organism=Drosophila melanogaster, GI24641198, Length=263, Percent_Identity=29.277566539924, Blast_Score=103, Evalue=1e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004390
- InterPro:   IPR003593
- InterPro:   IPR000897
- InterPro:   IPR013822 [H]

Pfam domain/function: PF00448 SRP54; PF02881 SRP54_N [H]

EC number: NA

Molecular weight: Translated: 39570; Mature: 39570

Theoretical pI: Translated: 6.96; Mature: 6.96

Prosite motif: PS00300 SRP54

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFGFFKKSGKPEPAGRDPQPASPSAEQAPAIAADAPVAAPAPISPVPAQPVTAPAEPAAA
CCCCCCCCCCCCCCCCCCCCCCCCHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
PKLSWGERLKAGLARTRQQLGGGLANLFGRRKIDEDLLEELETTLLMADCGVDATQYLLD
CCCCHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCHHHHHHH
ELRLRWKRDRLETADQLQAALADALHKIIAPLEQPLDVSGHKPYIIMIAGVNGSGKTTSI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEECCCCCCCCHH
GKLAKYFQAQGKSVLLAAGDTFRAAAREQLMTWGERNNVTVIAQDGGDAAAVIFDAINAA
HHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHCCCCCCEEEEEECCCCCHHHHHHHHHHH
RARGIDIVLADTAGRLPTQLHLMEEIAKVRRVIAKADASGPHEVVLVLDANIGQNALAQV
HHCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCHHHHHHH
KAFDAAIGVTGLVVTKLDGTAKGGVVAAIARQCPKPLRFIGVGEGIDDLQPFKAREFIDA
HHHHHHHCCCEEEEEECCCCCCCCHHHHHHHHCCCCEEEEECCCCCCCCCCHHHHHHHHH
LFEPAPAGATKRGDASA
HHCCCCCCCCCCCCCCC
>Mature Secondary Structure
MFGFFKKSGKPEPAGRDPQPASPSAEQAPAIAADAPVAAPAPISPVPAQPVTAPAEPAAA
CCCCCCCCCCCCCCCCCCCCCCCCHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
PKLSWGERLKAGLARTRQQLGGGLANLFGRRKIDEDLLEELETTLLMADCGVDATQYLLD
CCCCHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCHHHHHHH
ELRLRWKRDRLETADQLQAALADALHKIIAPLEQPLDVSGHKPYIIMIAGVNGSGKTTSI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEECCCCCCCCHH
GKLAKYFQAQGKSVLLAAGDTFRAAAREQLMTWGERNNVTVIAQDGGDAAAVIFDAINAA
HHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHCCCCCCEEEEEECCCCCHHHHHHHHHHH
RARGIDIVLADTAGRLPTQLHLMEEIAKVRRVIAKADASGPHEVVLVLDANIGQNALAQV
HHCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCHHHHHHH
KAFDAAIGVTGLVVTKLDGTAKGGVVAAIARQCPKPLRFIGVGEGIDDLQPFKAREFIDA
HHHHHHHCCCEEEEEECCCCCCCCHHHHHHHHCCCCEEEEECCCCCCCCCCHHHHHHHHH
LFEPAPAGATKRGDASA
HHCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 10761919 [H]