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The map label for this gene is ubiE [H]

Identifier: 119897001

GI number: 119897001

Start: 758634

End: 759479

Strand: Reverse

Name: ubiE [H]

Synonym: azo0710

Alternate gene names: 119897001

Gene position: 759479-758634 (Counterclockwise)

Preceding gene: 119897002

Following gene: 119897000

Centisome position: 17.36

GC content: 76.0

Gene sequence:

>846_bases
ATGACCCAGGACGCCCCCTTCGACCCGCGGCGCTTCAAGGCGCAGGAACGCGCCGGCTTCAACCGCATCGCAGCGCGCTA
CGCCGGCGGTGCGCCACTGCGTGCAGCGCTTGCCGAGGCCGTGCTGAACGCCGCCCGGCTCGAACCCGGCCTGCGCGTGC
TCGACCTCGCCAGCGGCCCCGGCCTGCTCGCCCTCCCCGCCGCCACGCAGGTCGCGCCTCACGGCTGGGTACTTGCCACC
GACATTGCCGAAACCATGCTGGCCGAAGCGGCGCGGCGCAGCGACGACACCGCGCCGCTGCTGTTCGCCGCCGCCGACGC
GGAACACCTGTGCGTGCCGGACGCGTCGATCGACCGCGTGCTCGCCGGCCTCGCGCTGTTCCTGTTCCCCGACCCGGCAC
GCGCGCTGGCGGAGGTCGGGCGCGTGCTCGCCCCCGGCGGGCGGGTCGTGCTGTCGGTGTGGGGGCCGCGCGCCGAGGTG
CCGCTGCTGCACCGCGCGCAAGATGCCATCGCCACCGCGCTGGGGCCGCCGCGGGTGGCGCGCCCCTCGGTGTTCCGGCT
CGGCGAAGCCGGCGCGCTCGCGCAGTTGCTCGACGCCGCCGGCTTCACCGATATCCGGGTCGAACCCTGCTCCTTCAGCT
GCCCGTTCGACGATGCCGACGCCTACTGGCAGGCTTTTCTCGACCTCGCCGGCGGCGTGGCCGAGGCCATGGCGCAGGTG
CCCGAATCCCGCCTCGCCGCCGTGCGCGCTGCGGTGGCCGACGCGATCGCTCCGCACCGGCTGCCCGCCGGCGGCTACCG
GCTGCCCGCCACCGCGCTGGTCGCAGTGGCGCGCCGGCCCGACTGA

Upstream 100 bases:

>100_bases
CGGCGACCACGGCTTTTCGCGCTGGAACGACTACCTCGACGACGTCATCGCCTTTGCCGGGCCGGTCTGAACCCGTCCCG
CCCCGTCAACCGGAGCCCGC

Downstream 100 bases:

>100_bases
CGGCCCCCCGGCAAGGGCCGCGAATCCAGTAAACTGTGCGGCTTGCTCATTCCCTGGCGGTAGTCGATGTTCGTGCTGTT
CGAAGAGGACGGGGCCTTCA

Product: putative methyltransferase

Products: S-Adenosyl-L-Homocysteine; @OCTA02.txt*2- Polyprenyl-3-Methyl-6-Methoxy-1,4-Benzoquinol!; Menaquinol. [C]

Alternate protein names: NA

Number of amino acids: Translated: 281; Mature: 280

Protein sequence:

>281_residues
MTQDAPFDPRRFKAQERAGFNRIAARYAGGAPLRAALAEAVLNAARLEPGLRVLDLASGPGLLALPAATQVAPHGWVLAT
DIAETMLAEAARRSDDTAPLLFAAADAEHLCVPDASIDRVLAGLALFLFPDPARALAEVGRVLAPGGRVVLSVWGPRAEV
PLLHRAQDAIATALGPPRVARPSVFRLGEAGALAQLLDAAGFTDIRVEPCSFSCPFDDADAYWQAFLDLAGGVAEAMAQV
PESRLAAVRAAVADAIAPHRLPAGGYRLPATALVAVARRPD

Sequences:

>Translated_281_residues
MTQDAPFDPRRFKAQERAGFNRIAARYAGGAPLRAALAEAVLNAARLEPGLRVLDLASGPGLLALPAATQVAPHGWVLAT
DIAETMLAEAARRSDDTAPLLFAAADAEHLCVPDASIDRVLAGLALFLFPDPARALAEVGRVLAPGGRVVLSVWGPRAEV
PLLHRAQDAIATALGPPRVARPSVFRLGEAGALAQLLDAAGFTDIRVEPCSFSCPFDDADAYWQAFLDLAGGVAEAMAQV
PESRLAAVRAAVADAIAPHRLPAGGYRLPATALVAVARRPD
>Mature_280_residues
TQDAPFDPRRFKAQERAGFNRIAARYAGGAPLRAALAEAVLNAARLEPGLRVLDLASGPGLLALPAATQVAPHGWVLATD
IAETMLAEAARRSDDTAPLLFAAADAEHLCVPDASIDRVLAGLALFLFPDPARALAEVGRVLAPGGRVVLSVWGPRAEVP
LLHRAQDAIATALGPPRVARPSVFRLGEAGALAQLLDAAGFTDIRVEPCSFSCPFDDADAYWQAFLDLAGGVAEAMAQVP
ESRLAAVRAAVADAIAPHRLPAGGYRLPATALVAVARRPD

Specific function: Methyltransferase required for the conversion of dimethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) [H]

COG id: COG0500

COG function: function code QR; SAM-dependent methyltransferases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. UbiE family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004033 [H]

Pfam domain/function: PF01209 Ubie_methyltran [H]

EC number: 2.1.1.- [C]

Molecular weight: Translated: 29306; Mature: 29175

Theoretical pI: Translated: 5.72; Mature: 5.72

Prosite motif: PS00041 HTH_ARAC_FAMILY_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQDAPFDPRRFKAQERAGFNRIAARYAGGAPLRAALAEAVLNAARLEPGLRVLDLASGP
CCCCCCCCHHHHHHHHHCCHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCEEEEECCCC
GLLALPAATQVAPHGWVLATDIAETMLAEAARRSDDTAPLLFAAADAEHLCVPDASIDRV
CEEEECCHHHCCCCCCEEHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCEECCCHHHHHH
LAGLALFLFPDPARALAEVGRVLAPGGRVVLSVWGPRAEVPLLHRAQDAIATALGPPRVA
HHHHHHHHCCCHHHHHHHHHHHCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHCCCCCCC
RPSVFRLGEAGALAQLLDAAGFTDIRVEPCSFSCPFDDADAYWQAFLDLAGGVAEAMAQV
CCCHHHCCCCHHHHHHHHHCCCCCEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHC
PESRLAAVRAAVADAIAPHRLPAGGYRLPATALVAVARRPD
CHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHCCCC
>Mature Secondary Structure 
TQDAPFDPRRFKAQERAGFNRIAARYAGGAPLRAALAEAVLNAARLEPGLRVLDLASGP
CCCCCCCHHHHHHHHHCCHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCEEEEECCCC
GLLALPAATQVAPHGWVLATDIAETMLAEAARRSDDTAPLLFAAADAEHLCVPDASIDRV
CEEEECCHHHCCCCCCEEHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCEECCCHHHHHH
LAGLALFLFPDPARALAEVGRVLAPGGRVVLSVWGPRAEVPLLHRAQDAIATALGPPRVA
HHHHHHHHCCCHHHHHHHHHHHCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHCCCCCCC
RPSVFRLGEAGALAQLLDAAGFTDIRVEPCSFSCPFDDADAYWQAFLDLAGGVAEAMAQV
CCCHHHCCCCHHHHHHHHHCCCCCEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHC
PESRLAAVRAAVADAIAPHRLPAGGYRLPATALVAVARRPD
CHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: S-Adenosyl-L-Methionine; 2-Polyprenyl-6- Methoxy-1,4-Benzoquinol; Demethylmenaquinol [C]

Specific reaction: S-Adenosyl-L-Methionine + @OCTA02.txt*2-Polyprenyl-6- Methoxy-1,4-Benzoquinol! = S-Adenosyl-L-Homocysteine + 2- Polyprenyl-3-Methyl-6-Methoxy -1,4-Benzoquinol S-Adenosyl-L-Methionine + Demethylmenaquinol = S-Adenosyl-L-Homocysteine + Menaquinol. [C]

General reaction: Transferring one-carbon groups; Methyltransferases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA