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The map label for this gene is mtgA

Identifier: 119896997

GI number: 119896997

Start: 754167

End: 754862

Strand: Reverse

Name: mtgA

Synonym: azo0706

Alternate gene names: 119896997

Gene position: 754862-754167 (Counterclockwise)

Preceding gene: 119896998

Following gene: 119896996

Centisome position: 17.25

GC content: 69.54

Gene sequence:

>696_bases
ATGAAGACGCTGTGGCGCTGGCTCGGCCGCGCCCTGCTCGCCGCCTTCGCGCTGTTGCTGCTCTGGCAGGTCTGGCTGTT
CGCGCAGGTGGCGTGGTGGCGCACGCACAATCCGGACAGCACCAGCTTCATGCGCCTGCGGCTCGATGCGCTGCAGGAGA
AGAAGCCGGACGCGCGCCTGCGCCACACCTGGGTGCCCTACGAGCAGATCTCCATCCACCTCAAGCGCGCCGTGGTCGCG
GCCGAGGACGACGGCTTCGTCGACCATGAGGGCTTCGACTGGGACGGCATCCAGCGCGCGCTGGAGAAGAACGAACGCAA
GGGCCGCCCGGTGTCCGGCGGCTCCACGATCAGCCAGCAGCTTGCCAAGAACCTCTTCCTGTCGCCCTCGCGCAGCTACT
TCCGCAAGGCGCAGGAGGCGGTGATCACCGTGATGATCGAGCAGCTGTGGAGCAAGCGCCGCATCCTCGAGGTGTATCTG
AACGTGGTCGAATGGGGCAACGGCATCTTCGGCGCCGAAGCCGCCGCGCGGCGCTATTACGGCCTGCCGGCCAGCCGCCT
CGGCCCTGCCGAAGCAGCGCGGCTGGCGGTGATGCTGCCCAACCCGCGCAAGTACGAGCGCAGCTTCGGGCCGCGCCTCG
CCGCCCACGCCGACCGCATCCGCGGCCGCATGGCCTGGGCCGAAGTCCCGCCCTGA

Upstream 100 bases:

>100_bases
TGCTGGTCGAGCAGGCCGCCGAGAGCTTCCTGCTGTGGCGCGGCGTGCGCCCCGACACCGCCCCGGTGCTGGCCGATCTG
CGCGCCCGTCTCGCCGCCGC

Downstream 100 bases:

>100_bases
TCGGCGCGTCGTGAGCGCGCGCGCGGTCGCTGCTCCGCCGGCGGGCGCCGCGTGGCGGCAAATCCGCCACAGCGGGCCGA
GCGGGGTCGCGCCGCGGCGC

Product: monofunctional biosynthetic peptidoglycan transglycosylase

Products: NA

Alternate protein names: Monofunctional TGase

Number of amino acids: Translated: 231; Mature: 231

Protein sequence:

>231_residues
MKTLWRWLGRALLAAFALLLLWQVWLFAQVAWWRTHNPDSTSFMRLRLDALQEKKPDARLRHTWVPYEQISIHLKRAVVA
AEDDGFVDHEGFDWDGIQRALEKNERKGRPVSGGSTISQQLAKNLFLSPSRSYFRKAQEAVITVMIEQLWSKRRILEVYL
NVVEWGNGIFGAEAAARRYYGLPASRLGPAEAARLAVMLPNPRKYERSFGPRLAAHADRIRGRMAWAEVPP

Sequences:

>Translated_231_residues
MKTLWRWLGRALLAAFALLLLWQVWLFAQVAWWRTHNPDSTSFMRLRLDALQEKKPDARLRHTWVPYEQISIHLKRAVVA
AEDDGFVDHEGFDWDGIQRALEKNERKGRPVSGGSTISQQLAKNLFLSPSRSYFRKAQEAVITVMIEQLWSKRRILEVYL
NVVEWGNGIFGAEAAARRYYGLPASRLGPAEAARLAVMLPNPRKYERSFGPRLAAHADRIRGRMAWAEVPP
>Mature_231_residues
MKTLWRWLGRALLAAFALLLLWQVWLFAQVAWWRTHNPDSTSFMRLRLDALQEKKPDARLRHTWVPYEQISIHLKRAVVA
AEDDGFVDHEGFDWDGIQRALEKNERKGRPVSGGSTISQQLAKNLFLSPSRSYFRKAQEAVITVMIEQLWSKRRILEVYL
NVVEWGNGIFGAEAAARRYYGLPASRLGPAEAARLAVMLPNPRKYERSFGPRLAAHADRIRGRMAWAEVPP

Specific function: Cell wall formation

COG id: COG0744

COG function: function code M; Membrane carboxypeptidase (penicillin-binding protein)

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein (Potential)

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 51 family

Homologues:

Organism=Escherichia coli, GI1789601, Length=163, Percent_Identity=50.3067484662577, Blast_Score=154, Evalue=4e-39,
Organism=Escherichia coli, GI87082258, Length=203, Percent_Identity=33.4975369458128, Blast_Score=103, Evalue=1e-23,
Organism=Escherichia coli, GI1786343, Length=155, Percent_Identity=39.3548387096774, Blast_Score=96, Evalue=2e-21,
Organism=Escherichia coli, GI1788867, Length=162, Percent_Identity=32.0987654320988, Blast_Score=62, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MTGA_AZOSB (A1K3B8)

Other databases:

- EMBL:   AM406670
- RefSeq:   YP_932210.1
- ProteinModelPortal:   A1K3B8
- SMR:   A1K3B8
- STRING:   A1K3B8
- GeneID:   4609216
- GenomeReviews:   AM406670_GR
- KEGG:   azo:azo0706
- eggNOG:   COG0744
- HOGENOM:   HBG685698
- OMA:   RISIHLK
- PhylomeDB:   A1K3B8
- ProtClustDB:   PRK00056
- BioCyc:   ASP62928:AZO0706-MONOMER
- HAMAP:   MF_00766
- InterPro:   IPR001264
- InterPro:   IPR011812
- TIGRFAMs:   TIGR02070

Pfam domain/function: PF00912 Transgly

EC number: 2.4.2.- [C]

Molecular weight: Translated: 26605; Mature: 26605

Theoretical pI: Translated: 10.86; Mature: 10.86

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x19ec5858)-;

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTLWRWLGRALLAAFALLLLWQVWLFAQVAWWRTHNPDSTSFMRLRLDALQEKKPDARL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCHH
RHTWVPYEQISIHLKRAVVAAEDDGFVDHEGFDWDGIQRALEKNERKGRPVSGGSTISQQ
HHCCCCHHHHHHHHHHHHEEECCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCHHHHHH
LAKNLFLSPSRSYFRKAQEAVITVMIEQLWSKRRILEVYLNVVEWGNGIFGAEAAARRYY
HHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHC
GLPASRLGPAEAARLAVMLPNPRKYERSFGPRLAAHADRIRGRMAWAEVPP
CCCHHHCCHHHHHEEEEECCCCHHHHHHCCCHHHHHHHHHHHHHCCCCCCH
>Mature Secondary Structure
MKTLWRWLGRALLAAFALLLLWQVWLFAQVAWWRTHNPDSTSFMRLRLDALQEKKPDARL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCHH
RHTWVPYEQISIHLKRAVVAAEDDGFVDHEGFDWDGIQRALEKNERKGRPVSGGSTISQQ
HHCCCCHHHHHHHHHHHHEEECCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCHHHHHH
LAKNLFLSPSRSYFRKAQEAVITVMIEQLWSKRRILEVYLNVVEWGNGIFGAEAAARRYY
HHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHC
GLPASRLGPAEAARLAVMLPNPRKYERSFGPRLAAHADRIRGRMAWAEVPP
CCCHHHCCHHHHHEEEEECCCCHHHHHHCCCHHHHHHHHHHHHHCCCCCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA