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The map label for this gene is aggA [H]

Identifier: 119896945

GI number: 119896945

Start: 684035

End: 685477

Strand: Direct

Name: aggA [H]

Synonym: azo0654

Alternate gene names: 119896945

Gene position: 684035-685477 (Clockwise)

Preceding gene: 119896942

Following gene: 119896946

Centisome position: 15.63

GC content: 69.58

Gene sequence:

>1443_bases
ATGAAGAAGGTTCGCACCCTGGTTTGCCTTGCCGTCCTGTCGACACTGCAGGTGGCGCCCGCGATCGCGGCGACGCCGGA
ACCCCTGCGCGACGCGGTGCGCAAGGCCGTGGTGTCCAACCCCGAAGTCCAGGCGCGCTGGCATGCGTTCCAGGGCGCGA
CGGCGGACCAGGATGCGGCGCGCGGCGGCTACTACCCGCAGGTGGACCTGAACGCCGCGATCGGCCGCGAGCGGATCGAC
CGTCCGACCACCGGCACCAATGACTACACGCACCGCGGCGCCACCCTGTCGCTCACCCAAATGGTGTACGACGGCTTCTT
CACCCAAAGTGAAGTCGCGCGGATGGGCTACGCGAAGCTCGCGCGCTACTACGAACTGATCGAGACCTCTGAAAGCGCCG
CGCTGGAAGTGGTTCGCGCCTATGGCGATGTCCTGCGCTACCGTGAGCTGGTGCGCCTCGCCAAGGCCAACTACGTCGAG
CACAAGCTGATTTCCGACCAGATCGCGCAGCGCGCCGGCGCCGGCGTCGGCCGCCGCGTCGACCAGGAACAGGCCAGCGG
CCGTCTGGCGCTCGCCGAATCCAACCTGCTGACCGAAGTCTCCAACCTGCACGACGTCACCGCGCGCTATCAGCGCCTGG
TGGGCGACACCCCGCCGGAAGCGCTGCCCGACCTCGGCGAAACCCTGACCGCGATGCCGCTGCCGGCCAACCCGCGCGAT
GCGCTGCGCGAAGCCTTCAACACCAGCCCGGCGATCAACGCCGCGGTCGAGAACGTGCGCGCCGGCCAGGCCCTGGTGGA
AAGCCGTCGCTCGGCCTACCACCCGCGCGTCGAACTGCAGGCCTACAAGTCGATCGACCGCAACCTCGACGGCGTCGATG
GCCGCTCCAGCGACAGCGTGGTGCAGCTCGTCTTCAACTACAACCTGTTCCGCGGCGGCGCCGACCAGGCCCGCCTGCGC
TCGGCGGCCGAGTCGCTCAACCAGTCCAAGGACCTGCGCGAGAAGGCCTGCCGCGACCTGCGCCAGACGCTGGCGATCGC
CTATAACGACACCCAGCGCCTGACCGAGCAGCTGCGCTACCTCGACCAGCACCAGCTGTCGATCGAGAAGGCGCGCGAGG
CCTACCGCCGCCAGTTCGACATCGGCCAGCGGACCCTGCTCGACCTGCTCGACACCGAGAACGAGTACTTCCAGGCCCGC
CGCGCCTACGCCAACGCGCGCTACGACCAGGTGATCGCGCAGGCGCGCACGCTGAACGGGCTGGGCAAGCTGATGAGCGC
GCTGGAAGTGGCGCGCGAGGACCTGCCGGCCGCGAAGGACATCGGCCAGGACCGCGCCGGCATCGACCCCGAAACCATGT
GCCCGCCGGAGGCGCCGTCGCCGCTGCAGGTCGACAAGGCCCAACTGCTGTCCGACGCGATGCGCGACGCCGGCCGCCGC
TGA

Upstream 100 bases:

>100_bases
TGCCATTACATGCTGTAACGATCCGATATCATGCGCCGCTACCCATGCTGGGGCGGTAACCAACGGCTCCGGCTTTCGTC
TTATTCCGTTTGGAGAGGTC

Downstream 100 bases:

>100_bases
GCGTCCGTTCGTCCGCGCCCGGCCGTTGAAGGGCAGGGCGCGACGCACCCGGGGCGGATGCCGCGGTTTGCTGCTCTAGA
ATGGAGCGCCATCCCGCCGC

Product: putative outer membrane efflux protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 480; Mature: 480

Protein sequence:

>480_residues
MKKVRTLVCLAVLSTLQVAPAIAATPEPLRDAVRKAVVSNPEVQARWHAFQGATADQDAARGGYYPQVDLNAAIGRERID
RPTTGTNDYTHRGATLSLTQMVYDGFFTQSEVARMGYAKLARYYELIETSESAALEVVRAYGDVLRYRELVRLAKANYVE
HKLISDQIAQRAGAGVGRRVDQEQASGRLALAESNLLTEVSNLHDVTARYQRLVGDTPPEALPDLGETLTAMPLPANPRD
ALREAFNTSPAINAAVENVRAGQALVESRRSAYHPRVELQAYKSIDRNLDGVDGRSSDSVVQLVFNYNLFRGGADQARLR
SAAESLNQSKDLREKACRDLRQTLAIAYNDTQRLTEQLRYLDQHQLSIEKAREAYRRQFDIGQRTLLDLLDTENEYFQAR
RAYANARYDQVIAQARTLNGLGKLMSALEVAREDLPAAKDIGQDRAGIDPETMCPPEAPSPLQVDKAQLLSDAMRDAGRR

Sequences:

>Translated_480_residues
MKKVRTLVCLAVLSTLQVAPAIAATPEPLRDAVRKAVVSNPEVQARWHAFQGATADQDAARGGYYPQVDLNAAIGRERID
RPTTGTNDYTHRGATLSLTQMVYDGFFTQSEVARMGYAKLARYYELIETSESAALEVVRAYGDVLRYRELVRLAKANYVE
HKLISDQIAQRAGAGVGRRVDQEQASGRLALAESNLLTEVSNLHDVTARYQRLVGDTPPEALPDLGETLTAMPLPANPRD
ALREAFNTSPAINAAVENVRAGQALVESRRSAYHPRVELQAYKSIDRNLDGVDGRSSDSVVQLVFNYNLFRGGADQARLR
SAAESLNQSKDLREKACRDLRQTLAIAYNDTQRLTEQLRYLDQHQLSIEKAREAYRRQFDIGQRTLLDLLDTENEYFQAR
RAYANARYDQVIAQARTLNGLGKLMSALEVAREDLPAAKDIGQDRAGIDPETMCPPEAPSPLQVDKAQLLSDAMRDAGRR
>Mature_480_residues
MKKVRTLVCLAVLSTLQVAPAIAATPEPLRDAVRKAVVSNPEVQARWHAFQGATADQDAARGGYYPQVDLNAAIGRERID
RPTTGTNDYTHRGATLSLTQMVYDGFFTQSEVARMGYAKLARYYELIETSESAALEVVRAYGDVLRYRELVRLAKANYVE
HKLISDQIAQRAGAGVGRRVDQEQASGRLALAESNLLTEVSNLHDVTARYQRLVGDTPPEALPDLGETLTAMPLPANPRD
ALREAFNTSPAINAAVENVRAGQALVESRRSAYHPRVELQAYKSIDRNLDGVDGRSSDSVVQLVFNYNLFRGGADQARLR
SAAESLNQSKDLREKACRDLRQTLAIAYNDTQRLTEQLRYLDQHQLSIEKAREAYRRQFDIGQRTLLDLLDTENEYFQAR
RAYANARYDQVIAQARTLNGLGKLMSALEVAREDLPAAKDIGQDRAGIDPETMCPPEAPSPLQVDKAQLLSDAMRDAGRR

Specific function: Involved in the efflux of toxic and relatively hydrophobic compounds. Influences survival inside the host [H]

COG id: COG1538

COG function: function code MU; Outer membrane protein

Gene ontology:

Cell location: Cell outer membrane (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family [H]

Homologues:

Organism=Escherichia coli, GI87082199, Length=472, Percent_Identity=23.3050847457627, Blast_Score=77, Evalue=3e-15,

Paralogues:

None

Copy number: 120 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 240 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003423
- InterPro:   IPR010130 [H]

Pfam domain/function: PF02321 OEP [H]

EC number: NA

Molecular weight: Translated: 53303; Mature: 53303

Theoretical pI: Translated: 7.13; Mature: 7.13

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKVRTLVCLAVLSTLQVAPAIAATPEPLRDAVRKAVVSNPEVQARWHAFQGATADQDAA
CCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCHHH
RGGYYPQVDLNAAIGRERIDRPTTGTNDYTHRGATLSLTQMVYDGFFTQSEVARMGYAKL
CCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHH
ARYYELIETSESAALEVVRAYGDVLRYRELVRLAKANYVEHKLISDQIAQRAGAGVGRRV
HHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
DQEQASGRLALAESNLLTEVSNLHDVTARYQRLVGDTPPEALPDLGETLTAMPLPANPRD
CHHHHCCCEEEEHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCHHH
ALREAFNTSPAINAAVENVRAGQALVESRRSAYHPRVELQAYKSIDRNLDGVDGRSSDSV
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCCHHH
VQLVFNYNLFRGGADQARLRSAAESLNQSKDLREKACRDLRQTLAIAYNDTQRLTEQLRY
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHH
LDQHQLSIEKAREAYRRQFDIGQRTLLDLLDTENEYFQARRAYANARYDQVIAQARTLNG
HHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
LGKLMSALEVAREDLPAAKDIGQDRAGIDPETMCPPEAPSPLQVDKAQLLSDAMRDAGRR
HHHHHHHHHHHHHHCCCHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MKKVRTLVCLAVLSTLQVAPAIAATPEPLRDAVRKAVVSNPEVQARWHAFQGATADQDAA
CCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCHHH
RGGYYPQVDLNAAIGRERIDRPTTGTNDYTHRGATLSLTQMVYDGFFTQSEVARMGYAKL
CCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHH
ARYYELIETSESAALEVVRAYGDVLRYRELVRLAKANYVEHKLISDQIAQRAGAGVGRRV
HHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
DQEQASGRLALAESNLLTEVSNLHDVTARYQRLVGDTPPEALPDLGETLTAMPLPANPRD
CHHHHCCCEEEEHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCHHH
ALREAFNTSPAINAAVENVRAGQALVESRRSAYHPRVELQAYKSIDRNLDGVDGRSSDSV
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCCHHH
VQLVFNYNLFRGGADQARLRSAAESLNQSKDLREKACRDLRQTLAIAYNDTQRLTEQLRY
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHH
LDQHQLSIEKAREAYRRQFDIGQRTLLDLLDTENEYFQARRAYANARYDQVIAQARTLNG
HHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
LGKLMSALEVAREDLPAAKDIGQDRAGIDPETMCPPEAPSPLQVDKAQLLSDAMRDAGRR
HHHHHHHHHHHHHHCCCHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12271122 [H]