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The map label for this gene is cyaA [H]

Identifier: 119896919

GI number: 119896919

Start: 655581

End: 657689

Strand: Direct

Name: cyaA [H]

Synonym: azo0628

Alternate gene names: 119896919

Gene position: 655581-657689 (Clockwise)

Preceding gene: 119896916

Following gene: 119896922

Centisome position: 14.98

GC content: 71.55

Gene sequence:

>2109_bases
ATGCGGCGTTTTCTCTTCCTCCTCGTCCTCGCGCTGTCCGTTGCCGCCGCTGCCGCCGCGCACTTGCTCCAGCCGGGCAT
GGCGAAGACCCTGCGATATGCCGTTTTCGACCAGTACCAGCGCTGGTTTCCGCGCCCGCCGTCGGCCGTCCCGGATGTGG
TGGTGGTCGATATCGACGACGAGAGCCTTTCCCGGCTGGGGCAGTGGCCCTGGCCGCGGACCCGCTTTGCCGTGCTGCAG
CGCCGGCTGGCGGAGGCAGGCGCGGTGGCGGTCGGGTACGACATCCTGTTCGCCGAGCGCGATCGCAGTTCCCCTGCGGT
GCTGGCACGTGATCTGGCGCTGCCCGGGGCGCTGGCGCGGGAGCTTGACGCCCTGCCGGACCACGACGAGGTCTTTGCCG
CCAGCCTTGGGGCGCCGCCCGCAGTGCTCGGTTTCGCCGTCGACCGCGAGAACGGTGGCGGCACGACCGGCGTGAAGTGG
CCGTTCCGCATCGTGACGCGGGGCGTCGACGCGCTGCCGGTGACGGCGGAGGCCCACGCGGCGGTGATGCCCTTGCCCGG
GTTGGCCGCCGCCGCGGCAGGGCTGGGCAGCATCAGCTTCGCCGCCGACGGCGATGGCGTGGTGCGCCGCGTACCCATGA
TGATGCGGCTGGCCGACGGGTGGGTGCCGGCGCTCGATGCCGAATTGCTGCGGCTTGCGGGCGGCGGGCACAACCTCGTG
CTGGAAGGCGAGGGCGGACAGCTTGCGGCGCTGCGGGTGGGCGCGCGGCGCCTGCCCGTCACGTCGGCCGGGGAAGCGTG
GCTCCACTACGCTGCGGCGCCCGAGCAGCCGTTCCTGCCAGCGTGGCGGGTGCTGTCGGCCGATGCGCCGCTCGCCTCGC
TGCAGGGGCGGATCGTGCTGGTGGGCAGCTCCGCCAAGGGCTTGCTGGATTTGCGTTTCAGTCCCTTGGGCGAGGTCGTG
CCCGGGATCGAAATCCATGCCCAGGCCTTGCGCCAGGCACTGGCGGGGCGCTTTCCGGTGCGGCCCCAATGGGCGGAAGC
GTTCGAGCTGCTGATGCTGCTTGCCGGCAGCCTTGGTGGCGTACTGGTGGCGCTGCGCCTGGCTGCGCTGCCGGCCGCGC
TGCTCGCCGGCGGCGCGGCGCTTGCGATGCTCGGGGCGGGCGCAGCGGCGTTCGCCGGCGGGCGGCTTCTGCTCGATCCC
GCGCTGCCGGTGTTGGCCACCCTCGTTGCGTCGGTCATGGCCGGCCTGGTGCGTTACCGGCACCAGGAGAGCCGCCAGCG
CTGGCTGCGTCAGGCCTTCGCGCGGTATCTGTCGCCCAATCTGGTGGACTACCTGGTGCGTCATCCGCAAGCCTTGAAGC
TGGGCGGCGAGCGCTGCGTGTGCAGTTTCGTATTCACCGATCTTGCCGGCTACACCCGCCTGATCGAGAGCCTGGCGCCG
GAACGCGCGGTGGGGCTGTTGAACGACTATCTCGAGGGCATGGTCGCCATCGCCTTCCGCCACCAGGGCACGCTCGACCG
CATCGTCGGCGACGCGGTGGCGGTGCTGTTCTCGGCGCCGCTGGCGCAGCCCGACCACGCCCGCCGCGCGCTCGCCTGCG
CCCTCGAGATGCACGCCTTCAGCGAGCGATATGCCGAAGGAGTGCGTGCGCAGGGCATCGCCTTCGGCCATACCCGCATC
GGCGTGCACAGCGGCGAGGTGATCGTCGGCAACTTCGGCGGGCAGACGATGTTCGACTACCGCGCGCTCGGCGACCCGGT
GAATACCGCGGCGCGGCTGGAGTCCGCCAACAAGTGGCTGGGTACGCGGATCTGCATCTCGGCGGCGGTGCGTGAGGCCT
GTCCGGACGTGGCGGCGCGTGCCGTGGGCACGGTGCGGTTGCAGGGCAAGAACAGTGCGCTGGCGGTGTTCGAACCACTG
CCGGGCGCCGGTCAGCCGGACTCCGCCTACGATGTCGCGTTCGATCTGCTCGACCGGGCACCGGATGCCGCACAGGCGGC
CTTCGCGCGCCTTGCGGCCGAACGGCCGGCAGACGGCCTGGTAGCGTTTCACCTGCAGCGCTTGCGGGCGGGCCACCGCG
GCACGCTGATCGAGATGGGCTACAAGTAG

Upstream 100 bases:

>100_bases
GATGATAATGGAGCCGGCAATCCGTTGCGCGCGGCGGCGCGTACCGCACGCCCTCCGTTAAGATCGCGGAATATTCCCCG
GGGCCTCAGGGCCGGTGTTG

Downstream 100 bases:

>100_bases
CCGGTCGTGGCGCGCAGGGACCGGCGCGGGGAGGCTCAGCGCACGGTGACTTCGACCCGGCGGTTGCGGGCTTCGTCGGT
GTTGTCCGCGGTTGGAACCA

Product: putative adenylate/guanylate cyclase

Products: NA

Alternate protein names: ATP pyrophosphate-lyase 1; Adenylyl cyclase 1; AC 1 [H]

Number of amino acids: Translated: 702; Mature: 702

Protein sequence:

>702_residues
MRRFLFLLVLALSVAAAAAAHLLQPGMAKTLRYAVFDQYQRWFPRPPSAVPDVVVVDIDDESLSRLGQWPWPRTRFAVLQ
RRLAEAGAVAVGYDILFAERDRSSPAVLARDLALPGALARELDALPDHDEVFAASLGAPPAVLGFAVDRENGGGTTGVKW
PFRIVTRGVDALPVTAEAHAAVMPLPGLAAAAAGLGSISFAADGDGVVRRVPMMMRLADGWVPALDAELLRLAGGGHNLV
LEGEGGQLAALRVGARRLPVTSAGEAWLHYAAAPEQPFLPAWRVLSADAPLASLQGRIVLVGSSAKGLLDLRFSPLGEVV
PGIEIHAQALRQALAGRFPVRPQWAEAFELLMLLAGSLGGVLVALRLAALPAALLAGGAALAMLGAGAAAFAGGRLLLDP
ALPVLATLVASVMAGLVRYRHQESRQRWLRQAFARYLSPNLVDYLVRHPQALKLGGERCVCSFVFTDLAGYTRLIESLAP
ERAVGLLNDYLEGMVAIAFRHQGTLDRIVGDAVAVLFSAPLAQPDHARRALACALEMHAFSERYAEGVRAQGIAFGHTRI
GVHSGEVIVGNFGGQTMFDYRALGDPVNTAARLESANKWLGTRICISAAVREACPDVAARAVGTVRLQGKNSALAVFEPL
PGAGQPDSAYDVAFDLLDRAPDAAQAAFARLAAERPADGLVAFHLQRLRAGHRGTLIEMGYK

Sequences:

>Translated_702_residues
MRRFLFLLVLALSVAAAAAAHLLQPGMAKTLRYAVFDQYQRWFPRPPSAVPDVVVVDIDDESLSRLGQWPWPRTRFAVLQ
RRLAEAGAVAVGYDILFAERDRSSPAVLARDLALPGALARELDALPDHDEVFAASLGAPPAVLGFAVDRENGGGTTGVKW
PFRIVTRGVDALPVTAEAHAAVMPLPGLAAAAAGLGSISFAADGDGVVRRVPMMMRLADGWVPALDAELLRLAGGGHNLV
LEGEGGQLAALRVGARRLPVTSAGEAWLHYAAAPEQPFLPAWRVLSADAPLASLQGRIVLVGSSAKGLLDLRFSPLGEVV
PGIEIHAQALRQALAGRFPVRPQWAEAFELLMLLAGSLGGVLVALRLAALPAALLAGGAALAMLGAGAAAFAGGRLLLDP
ALPVLATLVASVMAGLVRYRHQESRQRWLRQAFARYLSPNLVDYLVRHPQALKLGGERCVCSFVFTDLAGYTRLIESLAP
ERAVGLLNDYLEGMVAIAFRHQGTLDRIVGDAVAVLFSAPLAQPDHARRALACALEMHAFSERYAEGVRAQGIAFGHTRI
GVHSGEVIVGNFGGQTMFDYRALGDPVNTAARLESANKWLGTRICISAAVREACPDVAARAVGTVRLQGKNSALAVFEPL
PGAGQPDSAYDVAFDLLDRAPDAAQAAFARLAAERPADGLVAFHLQRLRAGHRGTLIEMGYK
>Mature_702_residues
MRRFLFLLVLALSVAAAAAAHLLQPGMAKTLRYAVFDQYQRWFPRPPSAVPDVVVVDIDDESLSRLGQWPWPRTRFAVLQ
RRLAEAGAVAVGYDILFAERDRSSPAVLARDLALPGALARELDALPDHDEVFAASLGAPPAVLGFAVDRENGGGTTGVKW
PFRIVTRGVDALPVTAEAHAAVMPLPGLAAAAAGLGSISFAADGDGVVRRVPMMMRLADGWVPALDAELLRLAGGGHNLV
LEGEGGQLAALRVGARRLPVTSAGEAWLHYAAAPEQPFLPAWRVLSADAPLASLQGRIVLVGSSAKGLLDLRFSPLGEVV
PGIEIHAQALRQALAGRFPVRPQWAEAFELLMLLAGSLGGVLVALRLAALPAALLAGGAALAMLGAGAAAFAGGRLLLDP
ALPVLATLVASVMAGLVRYRHQESRQRWLRQAFARYLSPNLVDYLVRHPQALKLGGERCVCSFVFTDLAGYTRLIESLAP
ERAVGLLNDYLEGMVAIAFRHQGTLDRIVGDAVAVLFSAPLAQPDHARRALACALEMHAFSERYAEGVRAQGIAFGHTRI
GVHSGEVIVGNFGGQTMFDYRALGDPVNTAARLESANKWLGTRICISAAVREACPDVAARAVGTVRLQGKNSALAVFEPL
PGAGQPDSAYDVAFDLLDRAPDAAQAAFARLAAERPADGLVAFHLQRLRAGHRGTLIEMGYK

Specific function: Unknown

COG id: COG4252

COG function: function code T; Predicted transmembrane sensor domain

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 guanylate cyclase domain [H]

Homologues:

Organism=Caenorhabditis elegans, GI71989805, Length=226, Percent_Identity=27.4336283185841, Blast_Score=68, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI71989822, Length=226, Percent_Identity=27.4336283185841, Blast_Score=67, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17508769, Length=188, Percent_Identity=28.7234042553192, Blast_Score=66, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054 [H]

Pfam domain/function: PF00211 Guanylate_cyc [H]

EC number: =4.6.1.1 [H]

Molecular weight: Translated: 74408; Mature: 74408

Theoretical pI: Translated: 8.47; Mature: 8.47

Prosite motif: PS50125 GUANYLATE_CYCLASES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRRFLFLLVLALSVAAAAAAHLLQPGMAKTLRYAVFDQYQRWFPRPPSAVPDVVVVDIDD
CHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCH
ESLSRLGQWPWPRTRFAVLQRRLAEAGAVAVGYDILFAERDRSSPAVLARDLALPGALAR
HHHHHCCCCCCCHHHHHHHHHHHHHCCCEEEEEEEEEEECCCCCHHHHHHHHCCCHHHHH
ELDALPDHDEVFAASLGAPPAVLGFAVDRENGGGTTGVKWPFRIVTRGVDALPVTAEAHA
HHHCCCCCHHHHHHHCCCCHHHEEEEEECCCCCCCCCCCCHHHHHHCCCCCCCCCCCCCE
AVMPLPGLAAAAAGLGSISFAADGDGVVRRVPMMMRLADGWVPALDAELLRLAGGGHNLV
EECCCCCHHHHHHCCCCEEECCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCEEE
LEGEGGQLAALRVGARRLPVTSAGEAWLHYAAAPEQPFLPAWRVLSADAPLASLQGRIVL
EECCCCEEEEEEECCCCCCCCCCCHHHEEECCCCCCCCCHHHHHHCCCCCHHHHCCCEEE
VGSSAKGLLDLRFSPLGEVVPGIEIHAQALRQALAGRFPVRPQWAEAFELLMLLAGSLGG
EECCCCCEEEECCCCHHHHCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCHHH
VLVALRLAALPAALLAGGAALAMLGAGAAAFAGGRLLLDPALPVLATLVASVMAGLVRYR
HHHHHHHHHHHHHHHHCHHHHHHHHCCHHHHCCCEEEECCHHHHHHHHHHHHHHHHHHHH
HQESRQRWLRQAFARYLSPNLVDYLVRHPQALKLGGERCVCSFVFTDLAGYTRLIESLAP
HHHHHHHHHHHHHHHHHCCHHHHHHHCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCC
ERAVGLLNDYLEGMVAIAFRHQGTLDRIVGDAVAVLFSAPLAQPDHARRALACALEMHAF
HHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHH
SERYAEGVRAQGIAFGHTRIGVHSGEVIVGNFGGQTMFDYRALGDPVNTAARLESANKWL
HHHHHCCCHHCCEEECCEEEEEECCCEEEECCCCCCEEHHHHCCCCHHHHHHHHHHHHHH
GTRICISAAVREACPDVAARAVGTVRLQGKNSALAVFEPLPGAGQPDSAYDVAFDLLDRA
HHHHHHHHHHHHHCHHHHHHHHEEEEEECCCCEEEEEECCCCCCCCCCHHHHHHHHHHCC
PDAAQAAFARLAAERPADGLVAFHLQRLRAGHRGTLIEMGYK
CCHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCEEECCCC
>Mature Secondary Structure
MRRFLFLLVLALSVAAAAAAHLLQPGMAKTLRYAVFDQYQRWFPRPPSAVPDVVVVDIDD
CHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCH
ESLSRLGQWPWPRTRFAVLQRRLAEAGAVAVGYDILFAERDRSSPAVLARDLALPGALAR
HHHHHCCCCCCCHHHHHHHHHHHHHCCCEEEEEEEEEEECCCCCHHHHHHHHCCCHHHHH
ELDALPDHDEVFAASLGAPPAVLGFAVDRENGGGTTGVKWPFRIVTRGVDALPVTAEAHA
HHHCCCCCHHHHHHHCCCCHHHEEEEEECCCCCCCCCCCCHHHHHHCCCCCCCCCCCCCE
AVMPLPGLAAAAAGLGSISFAADGDGVVRRVPMMMRLADGWVPALDAELLRLAGGGHNLV
EECCCCCHHHHHHCCCCEEECCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCEEE
LEGEGGQLAALRVGARRLPVTSAGEAWLHYAAAPEQPFLPAWRVLSADAPLASLQGRIVL
EECCCCEEEEEEECCCCCCCCCCCHHHEEECCCCCCCCCHHHHHHCCCCCHHHHCCCEEE
VGSSAKGLLDLRFSPLGEVVPGIEIHAQALRQALAGRFPVRPQWAEAFELLMLLAGSLGG
EECCCCCEEEECCCCHHHHCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCHHH
VLVALRLAALPAALLAGGAALAMLGAGAAAFAGGRLLLDPALPVLATLVASVMAGLVRYR
HHHHHHHHHHHHHHHHCHHHHHHHHCCHHHHCCCEEEECCHHHHHHHHHHHHHHHHHHHH
HQESRQRWLRQAFARYLSPNLVDYLVRHPQALKLGGERCVCSFVFTDLAGYTRLIESLAP
HHHHHHHHHHHHHHHHHCCHHHHHHHCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCC
ERAVGLLNDYLEGMVAIAFRHQGTLDRIVGDAVAVLFSAPLAQPDHARRALACALEMHAF
HHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHH
SERYAEGVRAQGIAFGHTRIGVHSGEVIVGNFGGQTMFDYRALGDPVNTAARLESANKWL
HHHHHCCCHHCCEEECCEEEEEECCCEEEECCCCCCEEHHHHCCCCHHHHHHHHHHHHHH
GTRICISAAVREACPDVAARAVGTVRLQGKNSALAVFEPLPGAGQPDSAYDVAFDLLDRA
HHHHHHHHHHHHHCHHHHHHHHEEEEEECCCCEEEEEECCCCCCCCCCHHHHHHHHHHCC
PDAAQAAFARLAAERPADGLVAFHLQRLRAGHRGTLIEMGYK
CCHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9523018; 8418825 [H]