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The map label for this gene is xerC [H]

Identifier: 119896887

GI number: 119896887

Start: 625290

End: 626201

Strand: Direct

Name: xerC [H]

Synonym: azo0596

Alternate gene names: 119896887

Gene position: 625290-626201 (Clockwise)

Preceding gene: 119896886

Following gene: 119896888

Centisome position: 14.29

GC content: 71.49

Gene sequence:

>912_bases
ATGAGCGTGCCCCGCGAGGCGCCCCTCGCGCCGCTTACCGACGAGTGCGAGGCGTATCTCGCCTATCTCGGCGACCAGCG
CCGCGCCGCGCCGCTGACGCTCGAAAACTACCGGCGTGACCTGCACCGCCTCGAACGCCTGGGTGACGGCCGCGCACTGA
TGACGCTGGGCGCGGCCGACATCCGCCGCTTCGTCGCGCGCCTGCACGGCGAGGGGCTGTCGGGCCGTTCGATCGCGCGC
GTATTGTCGTGCTGGCGCGGCCTTTACCGCTGGCTGCTGAGGCGGCGGCTGATCCCGGCGAATCCCGTCGACGGGATCCG
GGCACCGAAATCGCCGCGGCTGCTGCCGCGCGCGCTGTCGCCGGACCAGGCGCAGGCACTGCTCGATCCGCCCGCGGAGG
CCGCGCTGGAAGTGCGCGACCTCGCGATGTTCGAACTCTTCTATTCCTCGGGCCTGCGGCTCTCGGAACTGGCGGGGCTC
GACGTTGGCGGCGGGCTGGACCCGGCCGAAGGCATGGTCACGGTGCTCGGCAAGCGCGGAAAGACGCGCAGCGTGCCGGT
CGGCGCGCACGCCTGGGCGGCGTTGAAGGCATGGGACACCGTCCGTGCCGCAATCGCCCCGGCGGCAGAGCCGGCGCTGT
TCGTCACCCGCTCCGGCCGCCGCATGAGCCCGTCGGCGATCCGCGACCGCCTCGCCCGGCGCGCGCGCTCGGTGGGACTC
GGCGTGCACGTCCATCCGCACATGTTGCGTCACAGCTTCGCCAGCCATCTTCTGCAATCCAGCGGCGACCTGCGCGCAGT
GCAGGAGCTGCTCGGGCACAGCAGCATCCGCAGCACCCAGGTGTATACCCACCTCGATTTTCAGCATCTGGCGCGAATCT
ACGACGCCGCTCATCCGCGCGCCCGCAAGTAG

Upstream 100 bases:

>100_bases
CTGCTGCGCGAACTGGCGTGACCGTGGCCAGTGCGCACCCACCGGTGCCGCCGGATGCGGGCGGCCGTGCCGCGGCGGCC
GGCACAGGGCAGCGGCTGGA

Downstream 100 bases:

>100_bases
GGCGGGGCGTTGCGTCCCTGCACCCCACTTTGGGTATCGAGATGTGTGGGCCTGGACTAGGCTTCGGATATCCTCGTTGC
AAATAAAACAACAGTCGCAA

Product: site-specific recombinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 303; Mature: 302

Protein sequence:

>303_residues
MSVPREAPLAPLTDECEAYLAYLGDQRRAAPLTLENYRRDLHRLERLGDGRALMTLGAADIRRFVARLHGEGLSGRSIAR
VLSCWRGLYRWLLRRRLIPANPVDGIRAPKSPRLLPRALSPDQAQALLDPPAEAALEVRDLAMFELFYSSGLRLSELAGL
DVGGGLDPAEGMVTVLGKRGKTRSVPVGAHAWAALKAWDTVRAAIAPAAEPALFVTRSGRRMSPSAIRDRLARRARSVGL
GVHVHPHMLRHSFASHLLQSSGDLRAVQELLGHSSIRSTQVYTHLDFQHLARIYDAAHPRARK

Sequences:

>Translated_303_residues
MSVPREAPLAPLTDECEAYLAYLGDQRRAAPLTLENYRRDLHRLERLGDGRALMTLGAADIRRFVARLHGEGLSGRSIAR
VLSCWRGLYRWLLRRRLIPANPVDGIRAPKSPRLLPRALSPDQAQALLDPPAEAALEVRDLAMFELFYSSGLRLSELAGL
DVGGGLDPAEGMVTVLGKRGKTRSVPVGAHAWAALKAWDTVRAAIAPAAEPALFVTRSGRRMSPSAIRDRLARRARSVGL
GVHVHPHMLRHSFASHLLQSSGDLRAVQELLGHSSIRSTQVYTHLDFQHLARIYDAAHPRARK
>Mature_302_residues
SVPREAPLAPLTDECEAYLAYLGDQRRAAPLTLENYRRDLHRLERLGDGRALMTLGAADIRRFVARLHGEGLSGRSIARV
LSCWRGLYRWLLRRRLIPANPVDGIRAPKSPRLLPRALSPDQAQALLDPPAEAALEVRDLAMFELFYSSGLRLSELAGLD
VGGGLDPAEGMVTVLGKRGKTRSVPVGAHAWAALKAWDTVRAAIAPAAEPALFVTRSGRRMSPSAIRDRLARRARSVGLG
VHVHPHMLRHSFASHLLQSSGDLRAVQELLGHSSIRSTQVYTHLDFQHLARIYDAAHPRARK

Specific function: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The xerC-xerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell div

COG id: COG4973

COG function: function code L; Site-specific recombinase XerC

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'phage' integrase family. XerC subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790244, Length=298, Percent_Identity=44.2953020134228, Blast_Score=248, Evalue=5e-67,
Organism=Escherichia coli, GI1789261, Length=293, Percent_Identity=36.8600682593857, Blast_Score=150, Evalue=1e-37,
Organism=Escherichia coli, GI1790767, Length=184, Percent_Identity=27.7173913043478, Blast_Score=75, Evalue=7e-15,
Organism=Escherichia coli, GI1790768, Length=173, Percent_Identity=32.3699421965318, Blast_Score=75, Evalue=7e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011010
- InterPro:   IPR013762
- InterPro:   IPR002104
- InterPro:   IPR010998
- InterPro:   IPR023109
- InterPro:   IPR004107
- InterPro:   IPR011931 [H]

Pfam domain/function: PF02899 Phage_integr_N; PF00589 Phage_integrase [H]

EC number: NA

Molecular weight: Translated: 33412; Mature: 33281

Theoretical pI: Translated: 11.33; Mature: 11.33

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVPREAPLAPLTDECEAYLAYLGDQRRAAPLTLENYRRDLHRLERLGDGRALMTLGAAD
CCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCCCCEEHHCHHH
IRRFVARLHGEGLSGRSIARVLSCWRGLYRWLLRRRLIPANPVDGIRAPKSPRLLPRALS
HHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCC
PDQAQALLDPPAEAALEVRDLAMFELFYSSGLRLSELAGLDVGGGLDPAEGMVTVLGKRG
CHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCCCCCCCHHHHHHHHHCCCC
KTRSVPVGAHAWAALKAWDTVRAAIAPAAEPALFVTRSGRRMSPSAIRDRLARRARSVGL
CCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHCC
GVHVHPHMLRHSFASHLLQSSGDLRAVQELLGHSSIRSTQVYTHLDFQHLARIYDAAHPR
CCEECHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCHHHEECCHHHHHHHHHHCCCC
ARK
CCC
>Mature Secondary Structure 
SVPREAPLAPLTDECEAYLAYLGDQRRAAPLTLENYRRDLHRLERLGDGRALMTLGAAD
CCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCCCCEEHHCHHH
IRRFVARLHGEGLSGRSIARVLSCWRGLYRWLLRRRLIPANPVDGIRAPKSPRLLPRALS
HHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCC
PDQAQALLDPPAEAALEVRDLAMFELFYSSGLRLSELAGLDVGGGLDPAEGMVTVLGKRG
CHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCCCCCCCHHHHHHHHHCCCC
KTRSVPVGAHAWAALKAWDTVRAAIAPAAEPALFVTRSGRRMSPSAIRDRLARRARSVGL
CCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHCC
GVHVHPHMLRHSFASHLLQSSGDLRAVQELLGHSSIRSTQVYTHLDFQHLARIYDAAHPR
CCEECHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCHHHEECCHHHHHHHHHHCCCC
ARK
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA