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The map label for this gene is amtD [C]

Identifier: 119896750

GI number: 119896750

Start: 490448

End: 491650

Strand: Direct

Name: amtD [C]

Synonym: azo0459

Alternate gene names: 119896750

Gene position: 490448-491650 (Clockwise)

Preceding gene: 119896749

Following gene: 119896752

Centisome position: 11.21

GC content: 68.66

Gene sequence:

>1203_bases
ATGGAACTCCATCACCCGGACAACGACGTCCTCTTCATTCTGCTGGGCGCCATCATGGTGCTCGCGATGCACGCCGGCTT
CGCCTTTCTGGAGCTTGGCACGGTACGCAAGAAGAACCAGGTCAACGCGCTGGTCAAGATCCTCAGCGACTTCTCGGTCT
CCGCGCTGGCCTATTTCTTCATCGGTTACGGCGTCGCCTACGGCATCCACTTCTTCTCCGGTGCCGAGGTGCTGCTCGAA
CGCAGCGGCTTCGAGCTGACCCGCTTCTTCTTCCTGCTGACCTTCGCCGCCGCGATTCCCGCCATCATCTCGGGCGGCAT
CGCCGAGCGCGCGCGCTTCGGCCCGCAGCTGATCGCCACCTTCGTGCTGGTCGGGCTGGTCTATCCCTTCTTCGAGGGCA
TCGCCTGGAACCAGCACTTCGGCTTCCAGGCCTGGCTGAAGGACAGCTTCGGCGCCGAATTCCACGACTTCGCCGGCTCG
GTGGTGGTGCACGCGGTGGGCGGCTGGATCGCGCTGCCGGCGGTGCTGCTGCTCGGCGCGCGCCGCGGCCGCTACCACAG
CAACGGCGCCATCGCCGCGCACCCGCCGTCGTCGATTCCCTTCCTCGCGCTGGGCGCGTGGATCCTCATCATCGGCTGGT
TCGGCTTCAACGTGATGAGCGCGCAGACGCTGGAGAAGATCAGCGGGCTGGTGGCGATCAACTCGCTGATGGCGATGGTG
GGCGGCACGCTGGCCGCGCTCGCGCTCGGCCGCAACGACCCCGGCTTCGCGCACAACGGTCCGCTCGCCGGCCTGGTCGC
GGTCTGCGCCGGCTCCGACGTGATGCACCCGCTTGGTGCGCTCGCGGTCGGCGCGGTCGCGGGGGCGCTGTTCGTGCAGA
TGTTCACGCTGACGCAGAACCGCTGGAAGATCGACGACGTGCTCGGCGTGTGGCCGCTGCACGGCCTGTGCGGGGCCTGG
GGCGGCATCGCCGCGGGCATCTTCGGCAGCACCGCGCTGGGTGGCGCGGGCGGGGTGGCCTTCCTGCCCCAGCTTGCCGG
CACCGTGCTCGGCGTGGCGATCGCCGCGGGCGGCGGCTTTGCGGTGTATGGCGCGCTCAAGCTGCTGGTCGGCCTGCGCC
TCGATCCGGAAGCGGAGTTCGAAGGCGCCGACCTGTCGATCCACAAGATTTCGGCCACCGCGGAACGCGAAACCGCGTGG
TAG

Upstream 100 bases:

>100_bases
CACTTATTCCGTTGGCGTTCGTTGCAAAGCCAACAAAATCAAGCCCTCGGGGTTGGCGTGATGCTTGCTTTTGGTGCGTC
GGCTTGATTCAGGAACCAAA

Downstream 100 bases:

>100_bases
GGCGTCCGGCGGCGGTCAGCGCCGCCGGATGAAGTCCGCGCCCACCTCCAGGGTGCCATCGCGCGTGAGCCGCGCAAGGG
CGCGGTACAGCGCCTCGTGG

Product: ammonia permease

Products: NH3 [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 400; Mature: 400

Protein sequence:

>400_residues
MELHHPDNDVLFILLGAIMVLAMHAGFAFLELGTVRKKNQVNALVKILSDFSVSALAYFFIGYGVAYGIHFFSGAEVLLE
RSGFELTRFFFLLTFAAAIPAIISGGIAERARFGPQLIATFVLVGLVYPFFEGIAWNQHFGFQAWLKDSFGAEFHDFAGS
VVVHAVGGWIALPAVLLLGARRGRYHSNGAIAAHPPSSIPFLALGAWILIIGWFGFNVMSAQTLEKISGLVAINSLMAMV
GGTLAALALGRNDPGFAHNGPLAGLVAVCAGSDVMHPLGALAVGAVAGALFVQMFTLTQNRWKIDDVLGVWPLHGLCGAW
GGIAAGIFGSTALGGAGGVAFLPQLAGTVLGVAIAAGGGFAVYGALKLLVGLRLDPEAEFEGADLSIHKISATAERETAW

Sequences:

>Translated_400_residues
MELHHPDNDVLFILLGAIMVLAMHAGFAFLELGTVRKKNQVNALVKILSDFSVSALAYFFIGYGVAYGIHFFSGAEVLLE
RSGFELTRFFFLLTFAAAIPAIISGGIAERARFGPQLIATFVLVGLVYPFFEGIAWNQHFGFQAWLKDSFGAEFHDFAGS
VVVHAVGGWIALPAVLLLGARRGRYHSNGAIAAHPPSSIPFLALGAWILIIGWFGFNVMSAQTLEKISGLVAINSLMAMV
GGTLAALALGRNDPGFAHNGPLAGLVAVCAGSDVMHPLGALAVGAVAGALFVQMFTLTQNRWKIDDVLGVWPLHGLCGAW
GGIAAGIFGSTALGGAGGVAFLPQLAGTVLGVAIAAGGGFAVYGALKLLVGLRLDPEAEFEGADLSIHKISATAERETAW
>Mature_400_residues
MELHHPDNDVLFILLGAIMVLAMHAGFAFLELGTVRKKNQVNALVKILSDFSVSALAYFFIGYGVAYGIHFFSGAEVLLE
RSGFELTRFFFLLTFAAAIPAIISGGIAERARFGPQLIATFVLVGLVYPFFEGIAWNQHFGFQAWLKDSFGAEFHDFAGS
VVVHAVGGWIALPAVLLLGARRGRYHSNGAIAAHPPSSIPFLALGAWILIIGWFGFNVMSAQTLEKISGLVAINSLMAMV
GGTLAALALGRNDPGFAHNGPLAGLVAVCAGSDVMHPLGALAVGAVAGALFVQMFTLTQNRWKIDDVLGVWPLHGLCGAW
GGIAAGIFGSTALGGAGGVAFLPQLAGTVLGVAIAAGGGFAVYGALKLLVGLRLDPEAEFEGADLSIHKISATAERETAW

Specific function: Involved In The Uptake Of Ammonia (Probable). [C]

COG id: COG0004

COG function: function code P; Ammonia permease

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ammonium transporter (TC 2.A.49) family [H]

Homologues:

Organism=Escherichia coli, GI1786656, Length=406, Percent_Identity=31.5270935960591, Blast_Score=126, Evalue=2e-30,
Organism=Caenorhabditis elegans, GI17550182, Length=439, Percent_Identity=30.5239179954442, Blast_Score=142, Evalue=2e-34,
Organism=Caenorhabditis elegans, GI17550180, Length=426, Percent_Identity=28.6384976525822, Blast_Score=140, Evalue=1e-33,
Organism=Caenorhabditis elegans, GI32564042, Length=432, Percent_Identity=28.0092592592593, Blast_Score=140, Evalue=1e-33,
Organism=Caenorhabditis elegans, GI133931100, Length=430, Percent_Identity=28.1395348837209, Blast_Score=117, Evalue=7e-27,
Organism=Saccharomyces cerevisiae, GI6324187, Length=348, Percent_Identity=27.5862068965517, Blast_Score=76, Evalue=1e-14,
Organism=Saccharomyces cerevisiae, GI6321559, Length=416, Percent_Identity=25.2403846153846, Blast_Score=74, Evalue=3e-14,
Organism=Saccharomyces cerevisiae, GI6325396, Length=362, Percent_Identity=25.6906077348066, Blast_Score=71, Evalue=3e-13,
Organism=Drosophila melanogaster, GI161078314, Length=416, Percent_Identity=29.5673076923077, Blast_Score=124, Evalue=2e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001905
- InterPro:   IPR018047 [H]

Pfam domain/function: PF00909 Ammonium_transp [H]

EC number: NA

Molecular weight: Translated: 41890; Mature: 41890

Theoretical pI: Translated: 6.71; Mature: 6.71

Prosite motif: PS01219 AMMONIUM_TRANSP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHCCCCCCCCCCCCCCEEEEEEECCCHHCCCC
>Mature Secondary Structure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HHHHHHHHHHCCCCCCCCCCCCCCEEEEEEECCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NH3 [Periplasm] [C]

Specific reaction: NH3 [Periplasm] = NH3 [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]