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The map label for this gene is trxB1 [H]

Identifier: 119896743

GI number: 119896743

Start: 482675

End: 483571

Strand: Reverse

Name: trxB1 [H]

Synonym: azo0452

Alternate gene names: 119896743

Gene position: 483571-482675 (Counterclockwise)

Preceding gene: 119896744

Following gene: 119896742

Centisome position: 11.05

GC content: 73.58

Gene sequence:

>897_bases
ATGTCGCAGGATTTCGATGCGCTGGTGATAGGCGGCGGCCCCGCCGGGCTGACCGGGGCGCTCTACCTCGCGCGCTTCCG
CCGCCGGGTGCGGCTGGTGGATGACGGTTGCAGCCGCGCCACCCGCATCCCGCGCTCGCACAACATGCCCGGCTACCCGG
ACGGCGTGCGCGGCGGCGAGCTGGTGGCGGCGATCCGGCTGCAGGCCACGCGCTACGGGGTCGATTTCGCCAGCGGCCGC
GTCACCGCCCTCGAACGCGAGGGCACACGTTTTTCCGCGCGCCTTGCCGACGGCAGCACCACGCACGCTCGTGCGGTGCT
GCTCGCCACCGGCGTCACCGACGTCGAGCCGCCGATGCCCTATCTGGCGGAGGCGGTGCGCAGCGGCGCGCTGCGCTACT
GCCCGGTGTGCGACGGCTACGAGGTCTCCGGCCAGACCGTCGGCGTGCTCGCCGATGGCGACGCCGGCGCGCGCGAGGCA
CTCTACCTGCGCGGCTTCACCGCCCGGCTGCACGTCTTCCCGCTGTCCGACACGGTTGAAATCTCGGCGCGCGAGCGCCA
GCGCCTGCGCGACGCCGACATCATGCTGGCGGAGCACGCGGTGGCCAGCCTGCGGCTCGCCGACGGCGGCGTCGTGGTGC
GCCACGGCGACTACGAAACCCGCTGCGACTCGGTGTACAGCGCGCTCGGCACCCGCATCCAGGCCGACCTCGCGCCCGAT
GCCGAGCGCGACGAGCAGGGCTATCTGCTGACCGACCGCCATCACATGACCAGCATCGGGGGCCTCTACGCCGCGGGTGA
CGTGGTGCAGGGCCTCAACCAGATCAGCGTCGCCACCGGCGGCGCCGCGATCGCGGCGGCTGCCATCCATCGCGCGCTGG
GGCCCGCCTGGGCCTGA

Upstream 100 bases:

>100_bases
CGCCGAAGCGGCGACCTGAGCGTGCGAAACCGGCGCCGCGCGGCGGAGCTTTTGCCGGCACGCGCGGTCGCACCCTGGGA
GGACTACCCGGGAGAGGGCG

Downstream 100 bases:

>100_bases
AAAGCCCTTACCGCCGCGCACCCGGCGGCTATAGTGCCGGCTTCCCGTCCGGAGTCCGCCGATGAAGCCGCTAGCCGCCC
TGTTCGCCGCCGTCCTCTGC

Product: putative thioredoxin-disulfide reductase

Products: NA

Alternate protein names: TR; TRXR [H]

Number of amino acids: Translated: 298; Mature: 297

Protein sequence:

>298_residues
MSQDFDALVIGGGPAGLTGALYLARFRRRVRLVDDGCSRATRIPRSHNMPGYPDGVRGGELVAAIRLQATRYGVDFASGR
VTALEREGTRFSARLADGSTTHARAVLLATGVTDVEPPMPYLAEAVRSGALRYCPVCDGYEVSGQTVGVLADGDAGAREA
LYLRGFTARLHVFPLSDTVEISARERQRLRDADIMLAEHAVASLRLADGGVVVRHGDYETRCDSVYSALGTRIQADLAPD
AERDEQGYLLTDRHHMTSIGGLYAAGDVVQGLNQISVATGGAAIAAAAIHRALGPAWA

Sequences:

>Translated_298_residues
MSQDFDALVIGGGPAGLTGALYLARFRRRVRLVDDGCSRATRIPRSHNMPGYPDGVRGGELVAAIRLQATRYGVDFASGR
VTALEREGTRFSARLADGSTTHARAVLLATGVTDVEPPMPYLAEAVRSGALRYCPVCDGYEVSGQTVGVLADGDAGAREA
LYLRGFTARLHVFPLSDTVEISARERQRLRDADIMLAEHAVASLRLADGGVVVRHGDYETRCDSVYSALGTRIQADLAPD
AERDEQGYLLTDRHHMTSIGGLYAAGDVVQGLNQISVATGGAAIAAAAIHRALGPAWA
>Mature_297_residues
SQDFDALVIGGGPAGLTGALYLARFRRRVRLVDDGCSRATRIPRSHNMPGYPDGVRGGELVAAIRLQATRYGVDFASGRV
TALEREGTRFSARLADGSTTHARAVLLATGVTDVEPPMPYLAEAVRSGALRYCPVCDGYEVSGQTVGVLADGDAGAREAL
YLRGFTARLHVFPLSDTVEISARERQRLRDADIMLAEHAVASLRLADGGVVVRHGDYETRCDSVYSALGTRIQADLAPDA
ERDEQGYLLTDRHHMTSIGGLYAAGDVVQGLNQISVATGGAAIAAAAIHRALGPAWA

Specific function: Unknown

COG id: COG0492

COG function: function code O; Thioredoxin reductase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family [H]

Homologues:

Organism=Escherichia coli, GI1787114, Length=302, Percent_Identity=24.1721854304636, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI87081763, Length=248, Percent_Identity=26.2096774193548, Blast_Score=66, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6320560, Length=302, Percent_Identity=25.4966887417219, Blast_Score=86, Evalue=1e-17,
Organism=Saccharomyces cerevisiae, GI6321898, Length=302, Percent_Identity=24.1721854304636, Blast_Score=85, Evalue=2e-17,

Paralogues:

None

Copy number: 808 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013027
- InterPro:   IPR008255
- InterPro:   IPR001327
- InterPro:   IPR000103
- InterPro:   IPR005982 [H]

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2 [H]

EC number: =1.8.1.9 [H]

Molecular weight: Translated: 31633; Mature: 31502

Theoretical pI: Translated: 6.72; Mature: 6.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQDFDALVIGGGPAGLTGALYLARFRRRVRLVDDGCSRATRIPRSHNMPGYPDGVRGGE
CCCCCCEEEECCCCCCHHHHHHHHHHHHHHEECCCCCHHHHCCCCCCCCCCCCCCCCCCC
LVAAIRLQATRYGVDFASGRVTALEREGTRFSARLADGSTTHARAVLLATGVTDVEPPMP
EEEEEEEEHHHCCCEECCCCEEEEECCCCEEEEEECCCCCCHHEEEEEEECCCCCCCCHH
YLAEAVRSGALRYCPVCDGYEVSGQTVGVLADGDAGAREALYLRGFTARLHVFPLSDTVE
HHHHHHHCCCEEECCCCCCEEECCCEEEEEECCCCCCCCEEEEEEEEEEEEEEECCCCEE
ISARERQRLRDADIMLAEHAVASLRLADGGVVVRHGDYETRCDSVYSALGTRIQADLAPD
ECHHHHHHHHHHHHHHHHHHHHEEEEECCCEEEECCCCHHHHHHHHHHHCCEEEECCCCC
AERDEQGYLLTDRHHMTSIGGLYAAGDVVQGLNQISVATGGAAIAAAAIHRALGPAWA
CCCCCCCCEEECCCHHHHHCCHHHHHHHHHHHHHEEEECCCHHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
SQDFDALVIGGGPAGLTGALYLARFRRRVRLVDDGCSRATRIPRSHNMPGYPDGVRGGE
CCCCCEEEECCCCCCHHHHHHHHHHHHHHEECCCCCHHHHCCCCCCCCCCCCCCCCCCC
LVAAIRLQATRYGVDFASGRVTALEREGTRFSARLADGSTTHARAVLLATGVTDVEPPMP
EEEEEEEEHHHCCCEECCCCEEEEECCCCEEEEEECCCCCCHHEEEEEEECCCCCCCCHH
YLAEAVRSGALRYCPVCDGYEVSGQTVGVLADGDAGAREALYLRGFTARLHVFPLSDTVE
HHHHHHHCCCEEECCCCCCEEECCCEEEEEECCCCCCCCEEEEEEEEEEEEEEECCCCEE
ISARERQRLRDADIMLAEHAVASLRLADGGVVVRHGDYETRCDSVYSALGTRIQADLAPD
ECHHHHHHHHHHHHHHHHHHHHEEEEECCCEEEECCCCHHHHHHHHHHHCCEEEECCCCC
AERDEQGYLLTDRHHMTSIGGLYAAGDVVQGLNQISVATGGAAIAAAAIHRALGPAWA
CCCCCCCCEEECCCHHHHHCCHHHHHHHHHHHHHEEEECCCHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]