Click here to switch to the map view.

The map label for this gene is ykoW [H]

Identifier: 119896717

GI number: 119896717

Start: 450142

End: 452085

Strand: Reverse

Name: ykoW [H]

Synonym: azo0426

Alternate gene names: 119896717

Gene position: 452085-450142 (Counterclockwise)

Preceding gene: 119896718

Following gene: 119896712

Centisome position: 10.33

GC content: 70.58

Gene sequence:

>1944_bases
ATGAGTTTTCCGCCGCGCCAGCCCCTGATCGGCCGCGACGCCAGCCCCGCCGCGCGTGGTTTCCTCGTAACGATCGCCGT
CGTCGTGCTGGTGGTCAGTATCGAATGGGCCGCGTGGCGCCAGTACCGCGCCTTCGAGCAGCGCCAGGCCACTGCTGAAT
TCGCCCGCATCGCGGACCAGGCCACGCTGTCGCTGATGCAGCAGACCGCGCATTACCGCAACGCCCTCCTCGCCTTGCGC
GCCACCTGGCTCGCATCGGAGCGTTTCGACCCGGACGAATTCGCCCGCTACGTGCGCGCCCTGTCGGCCCCGCAGAGCCT
GCCCGGCCTGCGCGCCTTCGCCTTCAACCGTGCGGTGGAGGAGCGCGACCGGGCCGCCTACGTGCAACGCATCCGGCGCG
AATACAGCGCCCACGACCCGATCTACAACCGCTTCGACATCTACCCGGACGGCATTCGCGAGCGCTACCACGTGGTCGAG
ATGATCCAGCCGCCGAGCGGCAACCAGCGGTCGCTGGGCTACGACCTCGGCACCAGCGACGTGCGCCGGGTCACTGTGGA
GCACGCGCTGCAGCACGGCTTCGCCGCCACGCCGCCGATCCAGCTGCAGCAGGCGCCGGGCGTGCTCGCGATCCTGATCC
TGGCGCCCTTGCGCAATGTCGCCGACACCACCGCCAGCGCCGCCGACACCCGCGACACGGTCGCGGCCTCCTTCCTGGTC
AACGAGATGGTCAACGCGGCGATCTCGCCGAGCCTGCGCAAGCAGTTCCATCTGCGGATCACCGACCTTGGCGCAACCGA
GGCGGCCATCGACACTGCGACACCGCTGTACGCAGACAACACGCCGCCCGGCGTCGACAGCGACCCACGCACCGTCACGC
GCGAGGAGAGTTTCGGCGGCCGGCGCTGGCAACTGCGTTTCCAGCCCACCGAACCGGCGGCGCGCCCGCTGGCGGATACG
GTGCTGTTCGGGCTGCTGGCCGCGGGTGCGCTGCTCGCGGGCCTGGTCAGCCACCTGGCCATGCAGCATGCGCGCCGGGT
GGTCCGCCATCAGGCCCTGGTGCGACTGGGTTCGGACTGCATCCTCGAACTCGACGCCGGCGGCCGGGTGCGCGAAGCCG
ACAACGCCGCGCAACGCATCACCGGACTTCCGCCGCGGGAATGGGAAGGTGAGCCGCTGTGGCGCAAGGTGGCCGAAGAA
GACGCGCTCGATGTCGAGCGCGCCGTGCGCCAGTGCATCGAACGCCGCGAACCGGTGGTGATCGAGTGCCGCGTCCCGGA
CGACAGCGGTGGTCCGCCGCGCTGGATCTCGATGCGGCTCGGCAACCACCTCGACCACCCCTACCTTGGCTGTCTGTTCG
CGCAGATCTCCAACATCGATGCGCGCAAGGAGGTCGAGGCGGAGGTGGCACGGCTGGCGTTCTACGACCCGCTGACCGGA
CTGCCCAATCGCCGCCTGCTCGAAGCGCGCGCCGAACTCACCCTCGCCGCCGCACGCCGTCACAACGGCCACGCGGCGGT
GATGGTGCTCGACCTCGACGGCTTCAAGGAAATCAACGACAGCGCCGGTCATGCCGTGGGAGATGAAGTGCTCGCCCAGC
TCGCCACCCGCCTGCGCCATGTCGTGCGCGACAGCGACACCGTCGCCCGGCTGGGCGGCGACGAGTTCGTGATCCTGCTC
GGCGAGCCGGCGGGCGAAGCCGAAGTCCGCACCGCGGCGGTACGCATCTCGCACGCGCTGACCGTGCCGCTCACGGCGGC
CGGCCACAACTGGCTGGTCACCGCCAGCGTCGGCATCGCGCTGCACCCCGATCACGGCGACAACTTCGCCGACCTGCTCG
GCGCGGCCGACACCGCGATGTACCGCAGCAAGCGCACCGGGCGCGGACTGACGACGGTGGCGAGCGGCCGCAGCGCCGGG
GCGACGCCGCGCAGCACGTATTGA

Upstream 100 bases:

>100_bases
CGGACGGTCATTGCGGAAGAAGGTCCGCCGCGCCATGGGCGCGCACGGCGGTCACCAAGCGAAGCGCCGGCCGCGGCGCC
GGCAAAGGGAGCGAACAAGA

Downstream 100 bases:

>100_bases
GAACTACAGCGCCAACGCCAGTGCCAGCGGCAGGAACAGCACCGCGGCGAGGTTGCCGATGAGCACCATGGACGCCACTT
TCTCGGGCTCCTGGCGGTAG

Product: GGDEF/PAS-domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 647; Mature: 646

Protein sequence:

>647_residues
MSFPPRQPLIGRDASPAARGFLVTIAVVVLVVSIEWAAWRQYRAFEQRQATAEFARIADQATLSLMQQTAHYRNALLALR
ATWLASERFDPDEFARYVRALSAPQSLPGLRAFAFNRAVEERDRAAYVQRIRREYSAHDPIYNRFDIYPDGIRERYHVVE
MIQPPSGNQRSLGYDLGTSDVRRVTVEHALQHGFAATPPIQLQQAPGVLAILILAPLRNVADTTASAADTRDTVAASFLV
NEMVNAAISPSLRKQFHLRITDLGATEAAIDTATPLYADNTPPGVDSDPRTVTREESFGGRRWQLRFQPTEPAARPLADT
VLFGLLAAGALLAGLVSHLAMQHARRVVRHQALVRLGSDCILELDAGGRVREADNAAQRITGLPPREWEGEPLWRKVAEE
DALDVERAVRQCIERREPVVIECRVPDDSGGPPRWISMRLGNHLDHPYLGCLFAQISNIDARKEVEAEVARLAFYDPLTG
LPNRRLLEARAELTLAAARRHNGHAAVMVLDLDGFKEINDSAGHAVGDEVLAQLATRLRHVVRDSDTVARLGGDEFVILL
GEPAGEAEVRTAAVRISHALTVPLTAAGHNWLVTASVGIALHPDHGDNFADLLGAADTAMYRSKRTGRGLTTVASGRSAG
ATPRSTY

Sequences:

>Translated_647_residues
MSFPPRQPLIGRDASPAARGFLVTIAVVVLVVSIEWAAWRQYRAFEQRQATAEFARIADQATLSLMQQTAHYRNALLALR
ATWLASERFDPDEFARYVRALSAPQSLPGLRAFAFNRAVEERDRAAYVQRIRREYSAHDPIYNRFDIYPDGIRERYHVVE
MIQPPSGNQRSLGYDLGTSDVRRVTVEHALQHGFAATPPIQLQQAPGVLAILILAPLRNVADTTASAADTRDTVAASFLV
NEMVNAAISPSLRKQFHLRITDLGATEAAIDTATPLYADNTPPGVDSDPRTVTREESFGGRRWQLRFQPTEPAARPLADT
VLFGLLAAGALLAGLVSHLAMQHARRVVRHQALVRLGSDCILELDAGGRVREADNAAQRITGLPPREWEGEPLWRKVAEE
DALDVERAVRQCIERREPVVIECRVPDDSGGPPRWISMRLGNHLDHPYLGCLFAQISNIDARKEVEAEVARLAFYDPLTG
LPNRRLLEARAELTLAAARRHNGHAAVMVLDLDGFKEINDSAGHAVGDEVLAQLATRLRHVVRDSDTVARLGGDEFVILL
GEPAGEAEVRTAAVRISHALTVPLTAAGHNWLVTASVGIALHPDHGDNFADLLGAADTAMYRSKRTGRGLTTVASGRSAG
ATPRSTY
>Mature_646_residues
SFPPRQPLIGRDASPAARGFLVTIAVVVLVVSIEWAAWRQYRAFEQRQATAEFARIADQATLSLMQQTAHYRNALLALRA
TWLASERFDPDEFARYVRALSAPQSLPGLRAFAFNRAVEERDRAAYVQRIRREYSAHDPIYNRFDIYPDGIRERYHVVEM
IQPPSGNQRSLGYDLGTSDVRRVTVEHALQHGFAATPPIQLQQAPGVLAILILAPLRNVADTTASAADTRDTVAASFLVN
EMVNAAISPSLRKQFHLRITDLGATEAAIDTATPLYADNTPPGVDSDPRTVTREESFGGRRWQLRFQPTEPAARPLADTV
LFGLLAAGALLAGLVSHLAMQHARRVVRHQALVRLGSDCILELDAGGRVREADNAAQRITGLPPREWEGEPLWRKVAEED
ALDVERAVRQCIERREPVVIECRVPDDSGGPPRWISMRLGNHLDHPYLGCLFAQISNIDARKEVEAEVARLAFYDPLTGL
PNRRLLEARAELTLAAARRHNGHAAVMVLDLDGFKEINDSAGHAVGDEVLAQLATRLRHVVRDSDTVARLGGDEFVILLG
EPAGEAEVRTAAVRISHALTVPLTAAGHNWLVTASVGIALHPDHGDNFADLLGAADTAMYRSKRTGRGLTTVASGRSAGA
TPRSTY

Specific function: Probable signaling protein whose physiological role is not yet known [H]

COG id: COG2199

COG function: function code T; FOG: GGDEF domain

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1788381, Length=302, Percent_Identity=30.4635761589404, Blast_Score=105, Evalue=1e-23,
Organism=Escherichia coli, GI145693134, Length=201, Percent_Identity=37.3134328358209, Blast_Score=103, Evalue=5e-23,
Organism=Escherichia coli, GI1786584, Length=187, Percent_Identity=35.8288770053476, Blast_Score=102, Evalue=5e-23,
Organism=Escherichia coli, GI1787541, Length=278, Percent_Identity=29.8561151079137, Blast_Score=102, Evalue=6e-23,
Organism=Escherichia coli, GI1787816, Length=159, Percent_Identity=42.1383647798742, Blast_Score=93, Evalue=7e-20,
Organism=Escherichia coli, GI1787802, Length=223, Percent_Identity=31.390134529148, Blast_Score=88, Evalue=2e-18,
Organism=Escherichia coli, GI1788956, Length=160, Percent_Identity=35.625, Blast_Score=87, Evalue=4e-18,
Organism=Escherichia coli, GI87081881, Length=183, Percent_Identity=33.879781420765, Blast_Score=85, Evalue=2e-17,
Organism=Escherichia coli, GI1787262, Length=162, Percent_Identity=33.3333333333333, Blast_Score=81, Evalue=2e-16,
Organism=Escherichia coli, GI87081977, Length=184, Percent_Identity=34.7826086956522, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI87082007, Length=159, Percent_Identity=33.3333333333333, Blast_Score=77, Evalue=3e-15,
Organism=Escherichia coli, GI87081974, Length=93, Percent_Identity=37.6344086021505, Blast_Score=70, Evalue=4e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR001633
- InterPro:   IPR005330
- InterPro:   IPR000014 [H]

Pfam domain/function: PF00563 EAL; PF00990 GGDEF; PF03707 MHYT [H]

EC number: NA

Molecular weight: Translated: 71008; Mature: 70877

Theoretical pI: Translated: 7.06; Mature: 7.06

Prosite motif: PS50839 CHASE ; PS50112 PAS ; PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSFPPRQPLIGRDASPAARGFLVTIAVVVLVVSIEWAAWRQYRAFEQRQATAEFARIADQ
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ATLSLMQQTAHYRNALLALRATWLASERFDPDEFARYVRALSAPQSLPGLRAFAFNRAVE
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHH
ERDRAAYVQRIRREYSAHDPIYNRFDIYPDGIRERYHVVEMIQPPSGNQRSLGYDLGTSD
HHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHEECCCCCCCCCCCCCCCCHH
VRRVTVEHALQHGFAATPPIQLQQAPGVLAILILAPLRNVADTTASAADTRDTVAASFLV
HHHHHHHHHHHCCCCCCCCCCEECCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHH
NEMVNAAISPSLRKQFHLRITDLGATEAAIDTATPLYADNTPPGVDSDPRTVTREESFGG
HHHHHHHCCHHHHHEEEEEEEECCCCHHHHHCCCCCCCCCCCCCCCCCCCCEECCCCCCC
RRWQLRFQPTEPAARPLADTVLFGLLAAGALLAGLVSHLAMQHARRVVRHQALVRLGSDC
CEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCE
ILELDAGGRVREADNAAQRITGLPPREWEGEPLWRKVAEEDALDVERAVRQCIERREPVV
EEEECCCCCCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEE
IECRVPDDSGGPPRWISMRLGNHLDHPYLGCLFAQISNIDARKEVEAEVARLAFYDPLTG
EEEECCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCC
LPNRRLLEARAELTLAAARRHNGHAAVMVLDLDGFKEINDSAGHAVGDEVLAQLATRLRH
CCCHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCHHHCCCCCCHHHHHHHHHHHHHHHH
VVRDSDTVARLGGDEFVILLGEPAGEAEVRTAAVRISHALTVPLTAAGHNWLVTASVGIA
HHCCCCHHHHCCCCEEEEEECCCCCCHHHHHHHHHHHHEEEEEEEECCCCEEEEEEEEEE
LHPDHGDNFADLLGAADTAMYRSKRTGRGLTTVASGRSAGATPRSTY
ECCCCCCCHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCCCCCCCC
>Mature Secondary Structure 
SFPPRQPLIGRDASPAARGFLVTIAVVVLVVSIEWAAWRQYRAFEQRQATAEFARIADQ
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ATLSLMQQTAHYRNALLALRATWLASERFDPDEFARYVRALSAPQSLPGLRAFAFNRAVE
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHH
ERDRAAYVQRIRREYSAHDPIYNRFDIYPDGIRERYHVVEMIQPPSGNQRSLGYDLGTSD
HHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHEECCCCCCCCCCCCCCCCHH
VRRVTVEHALQHGFAATPPIQLQQAPGVLAILILAPLRNVADTTASAADTRDTVAASFLV
HHHHHHHHHHHCCCCCCCCCCEECCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHH
NEMVNAAISPSLRKQFHLRITDLGATEAAIDTATPLYADNTPPGVDSDPRTVTREESFGG
HHHHHHHCCHHHHHEEEEEEEECCCCHHHHHCCCCCCCCCCCCCCCCCCCCEECCCCCCC
RRWQLRFQPTEPAARPLADTVLFGLLAAGALLAGLVSHLAMQHARRVVRHQALVRLGSDC
CEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCE
ILELDAGGRVREADNAAQRITGLPPREWEGEPLWRKVAEEDALDVERAVRQCIERREPVV
EEEECCCCCCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEE
IECRVPDDSGGPPRWISMRLGNHLDHPYLGCLFAQISNIDARKEVEAEVARLAFYDPLTG
EEEECCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCC
LPNRRLLEARAELTLAAARRHNGHAAVMVLDLDGFKEINDSAGHAVGDEVLAQLATRLRH
CCCHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCHHHCCCCCCHHHHHHHHHHHHHHHH
VVRDSDTVARLGGDEFVILLGEPAGEAEVRTAAVRISHALTVPLTAAGHNWLVTASVGIA
HHCCCCHHHHCCCCEEEEEECCCCCCHHHHHHHHHHHHEEEEEEEECCCCEEEEEEEEEE
LHPDHGDNFADLLGAADTAMYRSKRTGRGLTTVASGRSAGATPRSTY
ECCCCCCCHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377; 11728710 [H]