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The map label for this gene is csdB [H]

Identifier: 119896660

GI number: 119896660

Start: 391503

End: 393335

Strand: Direct

Name: csdB [H]

Synonym: azo0369

Alternate gene names: 119896660

Gene position: 391503-393335 (Clockwise)

Preceding gene: 119896659

Following gene: 119896661

Centisome position: 8.95

GC content: 70.49

Gene sequence:

>1833_bases
ATGACTATCCCGACACCTACAAGTAAGGGCGCCGAGGGTCTGTCCGGCGCGCCGCTGCCGGATCTGCCCGACGAGGCCAC
GCTCGGCGCGCTCGCCTCGGCGTTCTTTCGCGCGCTGCCCGGTGCCGCGCTGCCGCCGGCCGACCCCGTGCGGGCGCAGG
TGGCCTCGGCGCCCGAGCTGAGCCTTGCGCAGGGCGGCTCGCGGCTGGCGCCGGCCCCGGTGGCGTCCGATCCGGTCGAC
CCGGTTGGCGGCGCGGGGGCCTTCGTTGTGCCGCAAGCCTATGCTGCCGCGCTGCCGCAGGTTGCGCCGCCGCAGGTGCC
GGCCGGTGTGGCCGAGGGGCTGCCGCTGGCGGTGCCGGGTTCGCCGTATTACTTCATCGGCGAGGCGAGCCCGTATCTGC
AGTCCGGCGCGGCCCCCGCGTTGCCGGAAAACCGCGTCGTGGCGCGCAGCTTCGGGCTGCCGGGCGAGGGCGAGCTGAAG
GCGCTGCTGGCGGAGATTGCCGCCGGACGGCCCTTGGCGGATGCGCCGGCGGCGGACCCGGGCGGCCGCTTCTACTTCAT
CGACGCGGCGAAGGTGCCGGCAGCGGAGCCGGGCGCGCGGGCGCCGTTCGACGTCAATGCGGTGCGGCGCGACTTTCCCA
TCCTGCAGGAGCGGGTGAACGGCAAGCCGCTGGTGTGGTTCGACAACGCCGCGACCACCCACAAGCCGCAGGCGGTGATC
GACCGGCTGGCCCACTTCTACGCCCACGAAAACTCCAATATCCACCGTGGCGCGCACGAACTGGCGGCGCGCGCCACCGA
CGCCTACGAGGCGGCGCGGCAGAAGGTGCAGCGCTTCCTTGGCGCGGGTTCGGCGGACGAGATCATCTTCGTGCGCGGCG
CCACCGAGGCGATCAACCTGGTGGCGAAGACCTGGGGCGTGCAGAACATCGGCGAGGGCGACGAAATCGTGGTGTCGCTG
CTCGAACACCACGCCAACATCGTGCCGTGGCAGCAGCTTGCAGCCCAGGTCGGCGCCAAGATTCGAGTGATTCCGGTAGA
CGACAATGGCCAGCTGAAGCTCGACGAGTTGCAGAAGCTGCTCAATCCGCGCACCCGGCTGGTGTCGGTGACGCAGGTGT
CGAACGCGCTCGGCACCGTGACGCCGATCAAGCAGGTCATCGACATGGCCCATGCTGCCGGCGCCAGGGTGCTGGTAGAC
GGGGCGCAATCGGTGTCGCACATGCGGGTGAACGTGCAGGCGCTGGATGCGGACTTCTTCGTGTTCTCGGGCCACAAGAT
CTTCGGCCCGACCGGCATCGGCGTGGTGTACGGCAAGGCCGCGCTGCTGGAGCAGATGCCCCCTTGGCAGGGCGGCGGCA
ACATGATCGCGGACGTCACCTTCGAGCGCACGCTGTTCCAGCCCGCGCCCAACAAGTTCGAGGCCGGCACCGGCAACATC
GCCGACGCGGTCGGATTGGGGGCGGCGCTGGACTACGTGGAGCGCATCGGGCTGGAGAACATCGCGCGCTACGAGCACGA
CCTGCTGGTCTATGCCACCCGCGGGCTGTCGTCGATCGCCGGGGTACGCCTGATCGGCACCGCCGCGGACAAGGCCAGCG
TGGCGTCCTTCGTGCTCGCCGGGTATTCCACCGAGGAAGTGGGCCGCGCCCTCAACGAGGAAGGCATTGCGGTGCGCTCC
GGCCACCACTGCGCGCAGCCCATCCTGCGCCGCTTCGGGGTTGAAACCACGGTGCGGCCGTCGCTGGCGTTCTACAACAC
CTGCGAGGAAATCGACCGCATGCTCGCGGTGGTGCGCCGTCTGGCGCGCGGCAAGGGCCGGGTGGGCGCCTGA

Upstream 100 bases:

>100_bases
AACGCCATCGCGTCCTACCTGATCTCGCTGTACTGCTCGCTGGCCGTACTGGTGCCGGATGCCCTGGCGGTTCTCGATGA
CGTGGAGGTCGGCAAGTACC

Downstream 100 bases:

>100_bases
GGCCCGCCCGTGCGCAGCGGCGCCATGCCGGCCGCTGCGCACGGGTGCTGGACGCCGCACCGCGTCATCGCTAATATCCG
CGCCTTCATTGGGGAGTAGC

Product: cysteine desulphurase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 610; Mature: 609

Protein sequence:

>610_residues
MTIPTPTSKGAEGLSGAPLPDLPDEATLGALASAFFRALPGAALPPADPVRAQVASAPELSLAQGGSRLAPAPVASDPVD
PVGGAGAFVVPQAYAAALPQVAPPQVPAGVAEGLPLAVPGSPYYFIGEASPYLQSGAAPALPENRVVARSFGLPGEGELK
ALLAEIAAGRPLADAPAADPGGRFYFIDAAKVPAAEPGARAPFDVNAVRRDFPILQERVNGKPLVWFDNAATTHKPQAVI
DRLAHFYAHENSNIHRGAHELAARATDAYEAARQKVQRFLGAGSADEIIFVRGATEAINLVAKTWGVQNIGEGDEIVVSL
LEHHANIVPWQQLAAQVGAKIRVIPVDDNGQLKLDELQKLLNPRTRLVSVTQVSNALGTVTPIKQVIDMAHAAGARVLVD
GAQSVSHMRVNVQALDADFFVFSGHKIFGPTGIGVVYGKAALLEQMPPWQGGGNMIADVTFERTLFQPAPNKFEAGTGNI
ADAVGLGAALDYVERIGLENIARYEHDLLVYATRGLSSIAGVRLIGTAADKASVASFVLAGYSTEEVGRALNEEGIAVRS
GHHCAQPILRRFGVETTVRPSLAFYNTCEEIDRMLAVVRRLARGKGRVGA

Sequences:

>Translated_610_residues
MTIPTPTSKGAEGLSGAPLPDLPDEATLGALASAFFRALPGAALPPADPVRAQVASAPELSLAQGGSRLAPAPVASDPVD
PVGGAGAFVVPQAYAAALPQVAPPQVPAGVAEGLPLAVPGSPYYFIGEASPYLQSGAAPALPENRVVARSFGLPGEGELK
ALLAEIAAGRPLADAPAADPGGRFYFIDAAKVPAAEPGARAPFDVNAVRRDFPILQERVNGKPLVWFDNAATTHKPQAVI
DRLAHFYAHENSNIHRGAHELAARATDAYEAARQKVQRFLGAGSADEIIFVRGATEAINLVAKTWGVQNIGEGDEIVVSL
LEHHANIVPWQQLAAQVGAKIRVIPVDDNGQLKLDELQKLLNPRTRLVSVTQVSNALGTVTPIKQVIDMAHAAGARVLVD
GAQSVSHMRVNVQALDADFFVFSGHKIFGPTGIGVVYGKAALLEQMPPWQGGGNMIADVTFERTLFQPAPNKFEAGTGNI
ADAVGLGAALDYVERIGLENIARYEHDLLVYATRGLSSIAGVRLIGTAADKASVASFVLAGYSTEEVGRALNEEGIAVRS
GHHCAQPILRRFGVETTVRPSLAFYNTCEEIDRMLAVVRRLARGKGRVGA
>Mature_609_residues
TIPTPTSKGAEGLSGAPLPDLPDEATLGALASAFFRALPGAALPPADPVRAQVASAPELSLAQGGSRLAPAPVASDPVDP
VGGAGAFVVPQAYAAALPQVAPPQVPAGVAEGLPLAVPGSPYYFIGEASPYLQSGAAPALPENRVVARSFGLPGEGELKA
LLAEIAAGRPLADAPAADPGGRFYFIDAAKVPAAEPGARAPFDVNAVRRDFPILQERVNGKPLVWFDNAATTHKPQAVID
RLAHFYAHENSNIHRGAHELAARATDAYEAARQKVQRFLGAGSADEIIFVRGATEAINLVAKTWGVQNIGEGDEIVVSLL
EHHANIVPWQQLAAQVGAKIRVIPVDDNGQLKLDELQKLLNPRTRLVSVTQVSNALGTVTPIKQVIDMAHAAGARVLVDG
AQSVSHMRVNVQALDADFFVFSGHKIFGPTGIGVVYGKAALLEQMPPWQGGGNMIADVTFERTLFQPAPNKFEAGTGNIA
DAVGLGAALDYVERIGLENIARYEHDLLVYATRGLSSIAGVRLIGTAADKASVASFVLAGYSTEEVGRALNEEGIAVRSG
HHCAQPILRRFGVETTVRPSLAFYNTCEEIDRMLAVVRRLARGKGRVGA

Specific function: Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine [H]

COG id: COG0520

COG function: function code E; Selenocysteine lyase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily [H]

Homologues:

Organism=Homo sapiens, GI32307132, Length=299, Percent_Identity=28.7625418060201, Blast_Score=104, Evalue=2e-22,
Organism=Homo sapiens, GI156713448, Length=272, Percent_Identity=27.9411764705882, Blast_Score=84, Evalue=3e-16,
Organism=Escherichia coli, GI1787970, Length=405, Percent_Identity=51.1111111111111, Blast_Score=427, Evalue=1e-120,
Organism=Escherichia coli, GI1789175, Length=398, Percent_Identity=41.4572864321608, Blast_Score=309, Evalue=4e-85,
Organism=Escherichia coli, GI48994898, Length=399, Percent_Identity=29.3233082706767, Blast_Score=115, Evalue=1e-26,
Organism=Caenorhabditis elegans, GI25143064, Length=213, Percent_Identity=28.6384976525822, Blast_Score=106, Evalue=4e-23,
Organism=Caenorhabditis elegans, GI193211090, Length=342, Percent_Identity=26.6081871345029, Blast_Score=87, Evalue=2e-17,
Organism=Saccharomyces cerevisiae, GI6319831, Length=230, Percent_Identity=30, Blast_Score=112, Evalue=2e-25,
Organism=Drosophila melanogaster, GI20129463, Length=420, Percent_Identity=27.3809523809524, Blast_Score=116, Evalue=4e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000192
- InterPro:   IPR010970
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00266 Aminotran_5 [H]

EC number: =2.8.1.7 [H]

Molecular weight: Translated: 63963; Mature: 63832

Theoretical pI: Translated: 6.33; Mature: 6.33

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTIPTPTSKGAEGLSGAPLPDLPDEATLGALASAFFRALPGAALPPADPVRAQVASAPEL
CCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHCCCCCC
SLAQGGSRLAPAPVASDPVDPVGGAGAFVVPQAYAAALPQVAPPQVPAGVAEGLPLAVPG
HHHCCCCCCCCCCCCCCCCCCCCCCCCEEHHHHHHHHCCCCCCCCCCCHHHCCCCEEECC
SPYYFIGEASPYLQSGAAPALPENRVVARSFGLPGEGELKALLAEIAAGRPLADAPAADP
CCEEEECCCCHHHHCCCCCCCCCCCEEHHHCCCCCCHHHHHHHHHHHCCCCCCCCCCCCC
GGRFYFIDAAKVPAAEPGARAPFDVNAVRRDFPILQERVNGKPLVWFDNAATTHKPQAVI
CCEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCHHHHH
DRLAHFYAHENSNIHRGAHELAARATDAYEAARQKVQRFLGAGSADEIIFVRGATEAINL
HHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCHHHHHH
VAKTWGVQNIGEGDEIVVSLLEHHANIVPWQQLAAQVGAKIRVIPVDDNGQLKLDELQKL
HHHHCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHCCEEEEEEECCCCCEEHHHHHHH
LNPRTRLVSVTQVSNALGTVTPIKQVIDMAHAAGARVLVDGAQSVSHMRVNVQALDADFF
HCCHHHEEEHHHHHHHHCCHHHHHHHHHHHHHCCCEEEEECHHHHHEEEEEEEEECCEEE
VFSGHKIFGPTGIGVVYGKAALLEQMPPWQGGGNMIADVTFERTLFQPAPNKFEAGTGNI
EEECCEEECCCCCHHHHHHHHHHHHCCCCCCCCCEEEEEEEHHHHCCCCCCCCCCCCCCH
ADAVGLGAALDYVERIGLENIARYEHDLLVYATRGLSSIAGVRLIGTAADKASVASFVLA
HHHHHHHHHHHHHHHHCHHHHHHHHCCEEEEEECCHHHHCCEEEEECCCCHHHHHHHHHH
GYSTEEVGRALNEEGIAVRSGHHCAQPILRRFGVETTVRPSLAFYNTCEEIDRMLAVVRR
CCCHHHHHHHHCCCCCEEECCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHH
LARGKGRVGA
HHCCCCCCCC
>Mature Secondary Structure 
TIPTPTSKGAEGLSGAPLPDLPDEATLGALASAFFRALPGAALPPADPVRAQVASAPEL
CCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHCCCCCC
SLAQGGSRLAPAPVASDPVDPVGGAGAFVVPQAYAAALPQVAPPQVPAGVAEGLPLAVPG
HHHCCCCCCCCCCCCCCCCCCCCCCCCEEHHHHHHHHCCCCCCCCCCCHHHCCCCEEECC
SPYYFIGEASPYLQSGAAPALPENRVVARSFGLPGEGELKALLAEIAAGRPLADAPAADP
CCEEEECCCCHHHHCCCCCCCCCCCEEHHHCCCCCCHHHHHHHHHHHCCCCCCCCCCCCC
GGRFYFIDAAKVPAAEPGARAPFDVNAVRRDFPILQERVNGKPLVWFDNAATTHKPQAVI
CCEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCHHHHH
DRLAHFYAHENSNIHRGAHELAARATDAYEAARQKVQRFLGAGSADEIIFVRGATEAINL
HHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCHHHHHH
VAKTWGVQNIGEGDEIVVSLLEHHANIVPWQQLAAQVGAKIRVIPVDDNGQLKLDELQKL
HHHHCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHCCEEEEEEECCCCCEEHHHHHHH
LNPRTRLVSVTQVSNALGTVTPIKQVIDMAHAAGARVLVDGAQSVSHMRVNVQALDADFF
HCCHHHEEEHHHHHHHHCCHHHHHHHHHHHHHCCCEEEEECHHHHHEEEEEEEEECCEEE
VFSGHKIFGPTGIGVVYGKAALLEQMPPWQGGGNMIADVTFERTLFQPAPNKFEAGTGNI
EEECCEEECCCCCHHHHHHHHHHHHCCCCCCCCCEEEEEEEHHHHCCCCCCCCCCCCCCH
ADAVGLGAALDYVERIGLENIARYEHDLLVYATRGLSSIAGVRLIGTAADKASVASFVLA
HHHHHHHHHHHHHHHHCHHHHHHHHCCEEEEEECCHHHHCCEEEEECCCCHHHHHHHHHH
GYSTEEVGRALNEEGIAVRSGHHCAQPILRRFGVETTVRPSLAFYNTCEEIDRMLAVVRR
CCCHHHHHHHHCCCCCEEECCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHH
LARGKGRVGA
HHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11234002 [H]