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The map label for this gene is hgiDIM [H]

Identifier: 119896645

GI number: 119896645

Start: 377176

End: 378156

Strand: Direct

Name: hgiDIM [H]

Synonym: azo0354

Alternate gene names: 119896645

Gene position: 377176-378156 (Clockwise)

Preceding gene: 119896640

Following gene: 119896656

Centisome position: 8.62

GC content: 58.0

Gene sequence:

>981_bases
ATGCCAACCTTTGTTGATCTCTTCTGTGGCGCGGGGTTTGGAGCACGCGGTGCAGTGCGAGGGGGTGGTGTTCCGTTGCT
TGGGCTTGATGCATGGAATCTCGCCACGGAGACCTACAAAGCCAACTTTCCCCAGGCAGATACCATCACTGAGAAGATCG
AGGATGTCGTCCCGAAGACGCTTGGTCGCAAGTACAGACCCGATGTGCTACTGACCTCACCAGAGTGCACTTCCCACTCG
ATTGCCCGTGGCGCTAAACCCGGGTTGGAAACAAGCCGTGAGACAGCGATCGGGATCGTCCCTTGGGTCGAGGCAATGGA
ACCACGCTGGGTCATTGTCGAGAACGTGAACCGGATGAAGAAATGGGATCGCCATGACGAACTGGTCCAGACCATCGAAG
GGCTTGGCTATGCGGTAAGCGATCTGCTGTTGAATTCCGCTGACTTCGGTTCGGCTCAGGCCCGCAAGCGCATGTTCCTG
GTGTGTGACAGGAAGGGAACCACGGTCGGCCGTGAAGATCTGCTCGGCTTGGTGAGTACGCCGAGGAAGACCGCTTACGA
CATCATCGACTGGGAAGCGGATTATCCGGCAACTCTGCTGCGGAAGCCGGGGCGTGCCCCGGCGACATTGGAAAGAGCGG
AGCGTGCCATTGCCGAGCTTGGGGTGGGGGTGCCTTTTCTGATCGTCTACTACGGCTCCGACTATGCGGGCGGATGGCAG
ACACTGGATGTTCCGCTCCGCACGGTGACTACGGTCGACCGTTTCGGTTTGGTGACATGGAAAGGAGATACTCCCTACTT
GCGCATGCTTCAACCTGCTGAGCTACTTCTCGCCATGGGAGGGGCAACGGAGCATGTCTTGCCTCATGGAAACCGGCGGG
ACAAAGTGAAACTCTGCGGCAATGGCGTGTGTTCGGACGTCATGACCGCCATTTTCCAGTGGATCTCGTTGAATCAGGCC
AAACAGCAGGACGCAGCCTGA

Upstream 100 bases:

>100_bases
TCGCTATCTCGCTTGACTGGACCCAGAAGCTGTTTATTTGGCGCCCTGTACCTGGTACGATCCTGCTTCTTTTTGTGCTA
GGCCAGACTGGAACTACCGG

Downstream 100 bases:

>100_bases
TCAGACGCTTGCCGTGATCCCATCCAGCCATGCATCGACTTGCGTCGGCGTCCGTACCCCGGCCGAACGCAACAGTCCGA
CGATGTCCTGCGCTGTGGTC

Product: putative methylase

Products: NA

Alternate protein names: M.HgiDI; Cytosine-specific methyltransferase HgiDI [H]

Number of amino acids: Translated: 326; Mature: 325

Protein sequence:

>326_residues
MPTFVDLFCGAGFGARGAVRGGGVPLLGLDAWNLATETYKANFPQADTITEKIEDVVPKTLGRKYRPDVLLTSPECTSHS
IARGAKPGLETSRETAIGIVPWVEAMEPRWVIVENVNRMKKWDRHDELVQTIEGLGYAVSDLLLNSADFGSAQARKRMFL
VCDRKGTTVGREDLLGLVSTPRKTAYDIIDWEADYPATLLRKPGRAPATLERAERAIAELGVGVPFLIVYYGSDYAGGWQ
TLDVPLRTVTTVDRFGLVTWKGDTPYLRMLQPAELLLAMGGATEHVLPHGNRRDKVKLCGNGVCSDVMTAIFQWISLNQA
KQQDAA

Sequences:

>Translated_326_residues
MPTFVDLFCGAGFGARGAVRGGGVPLLGLDAWNLATETYKANFPQADTITEKIEDVVPKTLGRKYRPDVLLTSPECTSHS
IARGAKPGLETSRETAIGIVPWVEAMEPRWVIVENVNRMKKWDRHDELVQTIEGLGYAVSDLLLNSADFGSAQARKRMFL
VCDRKGTTVGREDLLGLVSTPRKTAYDIIDWEADYPATLLRKPGRAPATLERAERAIAELGVGVPFLIVYYGSDYAGGWQ
TLDVPLRTVTTVDRFGLVTWKGDTPYLRMLQPAELLLAMGGATEHVLPHGNRRDKVKLCGNGVCSDVMTAIFQWISLNQA
KQQDAA
>Mature_325_residues
PTFVDLFCGAGFGARGAVRGGGVPLLGLDAWNLATETYKANFPQADTITEKIEDVVPKTLGRKYRPDVLLTSPECTSHSI
ARGAKPGLETSRETAIGIVPWVEAMEPRWVIVENVNRMKKWDRHDELVQTIEGLGYAVSDLLLNSADFGSAQARKRMFLV
CDRKGTTVGREDLLGLVSTPRKTAYDIIDWEADYPATLLRKPGRAPATLERAERAIAELGVGVPFLIVYYGSDYAGGWQT
LDVPLRTVTTVDRFGLVTWKGDTPYLRMLQPAELLLAMGGATEHVLPHGNRRDKVKLCGNGVCSDVMTAIFQWISLNQAK
QQDAA

Specific function: This methylase recognizes the double-stranded sequence GRCGYC, causes specific methylation on C-? on both strands, and protects the DNA from cleavage by the HgiDI endonuclease [H]

COG id: COG0270

COG function: function code L; Site-specific DNA methylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the C5-methyltransferase family [H]

Homologues:

Organism=Homo sapiens, GI4758184, Length=165, Percent_Identity=28.4848484848485, Blast_Score=73, Evalue=4e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018117
- InterPro:   IPR001525 [H]

Pfam domain/function: PF00145 DNA_methylase [H]

EC number: =2.1.1.37 [H]

Molecular weight: Translated: 35806; Mature: 35675

Theoretical pI: Translated: 6.91; Mature: 6.91

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPTFVDLFCGAGFGARGAVRGGGVPLLGLDAWNLATETYKANFPQADTITEKIEDVVPKT
CCCHHHHHHCCCCCCCCCCCCCCCCEEECCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHH
LGRKYRPDVLLTSPECTSHSIARGAKPGLETSRETAIGIVPWVEAMEPRWVIVENVNRMK
HCCCCCCCEEEECCCCCCHHHHCCCCCCCCCCCCCEEEEEHHHHHCCCCEEEECCHHHHH
KWDRHDELVQTIEGLGYAVSDLLLNSADFGSAQARKRMFLVCDRKGTTVGREDLLGLVST
HHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCHHHCCCEEEEECCCCCCCCHHHHHHHHCC
PRKTAYDIIDWEADYPATLLRKPGRAPATLERAERAIAELGVGVPFLIVYYGSDYAGGWQ
CCHHHHHEEECCCCCCHHHHCCCCCCCHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCE
TLDVPLRTVTTVDRFGLVTWKGDTPYLRMLQPAELLLAMGGATEHVLPHGNRRDKVKLCG
EECCCHHHHHHHHHHEEEEECCCCCCEECCCHHHHHHHCCCCCCCCCCCCCCCCEEEECC
NGVCSDVMTAIFQWISLNQAKQQDAA
CCCHHHHHHHHHHHHHHCHHHHCCCC
>Mature Secondary Structure 
PTFVDLFCGAGFGARGAVRGGGVPLLGLDAWNLATETYKANFPQADTITEKIEDVVPKT
CCHHHHHHCCCCCCCCCCCCCCCCEEECCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHH
LGRKYRPDVLLTSPECTSHSIARGAKPGLETSRETAIGIVPWVEAMEPRWVIVENVNRMK
HCCCCCCCEEEECCCCCCHHHHCCCCCCCCCCCCCEEEEEHHHHHCCCCEEEECCHHHHH
KWDRHDELVQTIEGLGYAVSDLLLNSADFGSAQARKRMFLVCDRKGTTVGREDLLGLVST
HHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCHHHCCCEEEEECCCCCCCCHHHHHHHHCC
PRKTAYDIIDWEADYPATLLRKPGRAPATLERAERAIAELGVGVPFLIVYYGSDYAGGWQ
CCHHHHHEEECCCCCCHHHHCCCCCCCHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCE
TLDVPLRTVTTVDRFGLVTWKGDTPYLRMLQPAELLLAMGGATEHVLPHGNRRDKVKLCG
EECCCHHHHHHHHHHEEEEECCCCCCEECCCHHHHHHHCCCCCCCCCCCCCCCCEEEECC
NGVCSDVMTAIFQWISLNQAKQQDAA
CCCHHHHHHHHHHHHHHCHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2020544; 7607523 [H]