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The map label for this gene is flp [H]

Identifier: 119896585

GI number: 119896585

Start: 317928

End: 319742

Strand: Reverse

Name: flp [H]

Synonym: azo0294

Alternate gene names: 119896585

Gene position: 319742-317928 (Counterclockwise)

Preceding gene: 119896587

Following gene: 119896584

Centisome position: 7.31

GC content: 70.19

Gene sequence:

>1815_bases
ATGCCCGCCTCGCCCCGCCCCGCCGCCCGCATCGCCCACCCCGTCGCCGCGCTGGCCCGCCGCCTGCTCGCCCCGGCCGC
GATCCTGCTGCTGGGCGCCTGCGCGGCCATCCAGCCGCCGCCGCGACCCGCCCACGTCGGCTCCGGCGACTACGCCTACA
CGCGCGACTACCTGCGCTGGCTGATCGGGCAGGAGATGGAAGAGAACCGCATCACCGGACTGTCGATCGCGCTGGTCGAC
GATCAGCGCGTGGTGTGGGCGGAAGGCTTCGGCAAGGAAGACGCCGAGCGCGACGTCGCCGCCGGCCCGCACACGCGTTA
CCGCATGGGTTCGATCGCGAAGGTGCTGACCGCGACCGCGGCGATGCAGATGGCCGAGCGCGGCGAGATCGACATCGACC
GCCCGCTGGCCGACTACCTGCCCGGCTTTTCGGTGCGCTCGCGCTTTGACGACCGCACCCCGATCACGCCGCGCAACATC
ATGCACCACCACTCCGGGCTGCCGGCGAACTACCTGAAGGGCATGATGGGCGGGGATCCGCCGCCCTTCACCACGCTGGT
GGAGGCCGTGCGCGAGGAATACGTCGCCTACCCGCCGGAATTCATCTTCGGCTACTCCAACCTGGCCGTCACACTGCTCG
GCGCGGCGCTCGAACAGCGCGCCGGCCTGCCCTTCGCCGACCACATGGCGAAAAGCCTGATCGAACCGCTGGGCATGACC
GAGACCCGCTTCGAATCCAACCCTGCGCTGCGGGTGTACGACGCGCGCGGGCAGATCGAGGCGCTGCCGCTGCGCGACCT
GCCCTCGGGCGGGCTGGTTTCCAGCGTGGCCGACATGAGCCGCTTCATGCGCATGGTGTTCGCCGGCGGACGCAGCGGAA
ACACCCAGCTGCTGCGCCCCGAAACCCTGCACGAGATGCTGCGCGCGCAGAACGAACACATCGCGCTCGACCTCGGTTTC
CGCGTCGGCCTGGGCTGGCTGCTGTCGGGCATCGAGATCCGCAACGCCGGCCTCGTCGCCAGCCACGGCGGCACCCTGTT
CGATTCGCACAGCATGATGGTGGTGCTGCCCGAGCACAAACTCGGCGTCATCGTCGCCTCCAACTCGGGCACCTCGCAGG
GCACGGTCAAGAAGATCGCCACCGAGGCGCTGATCCACGCGCTCGAAGCCAAGGCCGGCATCCGCCAGCCGGAGGCCGCC
GCGATCGCGCAGCCCGAAGTGCGGCTGGCGCCGGAGCAGCTGGCGTCCTATTCGGCCTGGTACGACTCCATGGTCGGCCT
CATCCGGGTCAAGCCGCGCGCGGGCGCGCTCGATGCCGACGTGATGGGCCACACGCTGCAGCTGCGCGCCCAGCCGGGCG
GCCAGTTCGGCCTGCGCTACAAGCTGTTCGGCCTGATTCCGGTGCAGGTCGGCGCGTTCGACGGCGTGCGCATCTCGGCG
GCGGCGATCGGCGGCCACGAAGTGCTGGTGGGCCACTTCGGCGACGACACCATGCTGGTCGGCGAAAAGCTCGCGCCGCG
CCCGATCCCGCGCACCATGCTCGACTACGTCGGCGAATACGAGATCGTCGGCAAACCGCCCGGCCTCGCGCCGGACCGCC
TCGCGCTGCGCGTGGAAGACGGCATGCTGATCGGCGAATGCAGCTTCTCGGAGTTGCCCGGCTTCATGCTGCGGATCGCG
CTCAACCCGATCTCGCCGACCGAGGCGGTCATCTCCGGCCTGGGCACCGGCAAGGGCGAAACCATCCGCATCCTGCCGGG
TGAAGGCCGCCGCCTGCTGTTCTCCGGCCTCGAACTGCGCCAGAAGACCAACTGA

Upstream 100 bases:

>100_bases
CGCGCGAGGAATCAGCGCACGGCGCCGACTTTCACACGGCGCCGTGCGGCCCCGTCACGTAACATCGCCGCCGCCCCGAT
TCATCCGACGTTCCAGCGCC

Downstream 100 bases:

>100_bases
GGCCCCTCGCCCCGTGAAGAAAGTCCTCGTCGTCCATTACTCGCAGACCGGCCAGCTCGCCGACATCGTCGGCACGCTGC
TGCAGCCGCTGCGCGCGGCG

Product: putative penicillin-binding protein

Products: NA

Alternate protein names: FmtA-like protein [H]

Number of amino acids: Translated: 604; Mature: 603

Protein sequence:

>604_residues
MPASPRPAARIAHPVAALARRLLAPAAILLLGACAAIQPPPRPAHVGSGDYAYTRDYLRWLIGQEMEENRITGLSIALVD
DQRVVWAEGFGKEDAERDVAAGPHTRYRMGSIAKVLTATAAMQMAERGEIDIDRPLADYLPGFSVRSRFDDRTPITPRNI
MHHHSGLPANYLKGMMGGDPPPFTTLVEAVREEYVAYPPEFIFGYSNLAVTLLGAALEQRAGLPFADHMAKSLIEPLGMT
ETRFESNPALRVYDARGQIEALPLRDLPSGGLVSSVADMSRFMRMVFAGGRSGNTQLLRPETLHEMLRAQNEHIALDLGF
RVGLGWLLSGIEIRNAGLVASHGGTLFDSHSMMVVLPEHKLGVIVASNSGTSQGTVKKIATEALIHALEAKAGIRQPEAA
AIAQPEVRLAPEQLASYSAWYDSMVGLIRVKPRAGALDADVMGHTLQLRAQPGGQFGLRYKLFGLIPVQVGAFDGVRISA
AAIGGHEVLVGHFGDDTMLVGEKLAPRPIPRTMLDYVGEYEIVGKPPGLAPDRLALRVEDGMLIGECSFSELPGFMLRIA
LNPISPTEAVISGLGTGKGETIRILPGEGRRLLFSGLELRQKTN

Sequences:

>Translated_604_residues
MPASPRPAARIAHPVAALARRLLAPAAILLLGACAAIQPPPRPAHVGSGDYAYTRDYLRWLIGQEMEENRITGLSIALVD
DQRVVWAEGFGKEDAERDVAAGPHTRYRMGSIAKVLTATAAMQMAERGEIDIDRPLADYLPGFSVRSRFDDRTPITPRNI
MHHHSGLPANYLKGMMGGDPPPFTTLVEAVREEYVAYPPEFIFGYSNLAVTLLGAALEQRAGLPFADHMAKSLIEPLGMT
ETRFESNPALRVYDARGQIEALPLRDLPSGGLVSSVADMSRFMRMVFAGGRSGNTQLLRPETLHEMLRAQNEHIALDLGF
RVGLGWLLSGIEIRNAGLVASHGGTLFDSHSMMVVLPEHKLGVIVASNSGTSQGTVKKIATEALIHALEAKAGIRQPEAA
AIAQPEVRLAPEQLASYSAWYDSMVGLIRVKPRAGALDADVMGHTLQLRAQPGGQFGLRYKLFGLIPVQVGAFDGVRISA
AAIGGHEVLVGHFGDDTMLVGEKLAPRPIPRTMLDYVGEYEIVGKPPGLAPDRLALRVEDGMLIGECSFSELPGFMLRIA
LNPISPTEAVISGLGTGKGETIRILPGEGRRLLFSGLELRQKTN
>Mature_603_residues
PASPRPAARIAHPVAALARRLLAPAAILLLGACAAIQPPPRPAHVGSGDYAYTRDYLRWLIGQEMEENRITGLSIALVDD
QRVVWAEGFGKEDAERDVAAGPHTRYRMGSIAKVLTATAAMQMAERGEIDIDRPLADYLPGFSVRSRFDDRTPITPRNIM
HHHSGLPANYLKGMMGGDPPPFTTLVEAVREEYVAYPPEFIFGYSNLAVTLLGAALEQRAGLPFADHMAKSLIEPLGMTE
TRFESNPALRVYDARGQIEALPLRDLPSGGLVSSVADMSRFMRMVFAGGRSGNTQLLRPETLHEMLRAQNEHIALDLGFR
VGLGWLLSGIEIRNAGLVASHGGTLFDSHSMMVVLPEHKLGVIVASNSGTSQGTVKKIATEALIHALEAKAGIRQPEAAA
IAQPEVRLAPEQLASYSAWYDSMVGLIRVKPRAGALDADVMGHTLQLRAQPGGQFGLRYKLFGLIPVQVGAFDGVRISAA
AIGGHEVLVGHFGDDTMLVGEKLAPRPIPRTMLDYVGEYEIVGKPPGLAPDRLALRVEDGMLIGECSFSELPGFMLRIAL
NPISPTEAVISGLGTGKGETIRILPGEGRRLLFSGLELRQKTN

Specific function: Its precise function is unknown. Has no penicillin- binding activity and is not involved in methicillin resistance [H]

COG id: COG1680

COG function: function code V; Beta-lactamase class C and other penicillin binding proteins

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI239747261, Length=278, Percent_Identity=24.1007194244604, Blast_Score=69, Evalue=1e-11,
Organism=Homo sapiens, GI239752721, Length=278, Percent_Identity=24.1007194244604, Blast_Score=69, Evalue=1e-11,
Organism=Homo sapiens, GI239741085, Length=278, Percent_Identity=24.1007194244604, Blast_Score=69, Evalue=1e-11,
Organism=Homo sapiens, GI26051231, Length=128, Percent_Identity=31.25, Blast_Score=67, Evalue=5e-11,
Organism=Homo sapiens, GI26051233, Length=128, Percent_Identity=31.25, Blast_Score=67, Evalue=5e-11,
Organism=Escherichia coli, GI1786574, Length=309, Percent_Identity=25.5663430420712, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI87082101, Length=312, Percent_Identity=25, Blast_Score=75, Evalue=9e-15,
Organism=Caenorhabditis elegans, GI115533026, Length=339, Percent_Identity=25.9587020648968, Blast_Score=100, Evalue=3e-21,
Organism=Caenorhabditis elegans, GI17550934, Length=288, Percent_Identity=27.4305555555556, Blast_Score=75, Evalue=8e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR001466 [H]

Pfam domain/function: PF00144 Beta-lactamase [H]

EC number: NA

Molecular weight: Translated: 65173; Mature: 65042

Theoretical pI: Translated: 6.97; Mature: 6.97

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPASPRPAARIAHPVAALARRLLAPAAILLLGACAAIQPPPRPAHVGSGDYAYTRDYLRW
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHH
LIGQEMEENRITGLSIALVDDQRVVWAEGFGKEDAERDVAAGPHTRYRMGSIAKVLTATA
HHCCCHHCCCCCEEEEEEECCCEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHH
AMQMAERGEIDIDRPLADYLPGFSVRSRFDDRTPITPRNIMHHHSGLPANYLKGMMGGDP
HHHHHHCCCCCCCCCHHHHCCCCCHHHCCCCCCCCCHHHHHHHCCCCCHHHHHHHCCCCC
PPFTTLVEAVREEYVAYPPEFIFGYSNLAVTLLGAALEQRAGLPFADHMAKSLIEPLGMT
CCHHHHHHHHHHHHCCCCCHHHCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCC
ETRFESNPALRVYDARGQIEALPLRDLPSGGLVSSVADMSRFMRMVFAGGRSGNTQLLRP
HHHCCCCCCEEEEECCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCEECH
ETLHEMLRAQNEHIALDLGFRVGLGWLLSGIEIRNAGLVASHGGTLFDSHSMMVVLPEHK
HHHHHHHHCCCCEEEEEECHHHHHHHHHCCCEEECCCEEEECCCEEEECCCEEEEECCCC
LGVIVASNSGTSQGTVKKIATEALIHALEAKAGIRQPEAAAIAQPEVRLAPEQLASYSAW
EEEEEECCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHCCCCCCEECHHHHHHHHHH
YDSMVGLIRVKPRAGALDADVMGHTLQLRAQPGGQFGLRYKLFGLIPVQVGAFDGVRISA
HHHCEEEEEECCCCCCCCHHHCCCEEEEEECCCCCCCEEEEEEEEEEEEECCCCCCEEEE
AAIGGHEVLVGHFGDDTMLVGEKLAPRPIPRTMLDYVGEYEIVGKPPGLAPDRLALRVED
EEECCCEEEEEECCCCEEEECCCCCCCCCCHHHHHHCCCEEEECCCCCCCCCCEEEEEEC
GMLIGECSFSELPGFMLRIALNPISPTEAVISGLGTGKGETIRILPGEGRRLLFSGLELR
CEEEEECCHHHCCCEEEEEEECCCCHHHHHHHHCCCCCCCEEEEECCCCCEEEECCHHHH
QKTN
HCCC
>Mature Secondary Structure 
PASPRPAARIAHPVAALARRLLAPAAILLLGACAAIQPPPRPAHVGSGDYAYTRDYLRW
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHH
LIGQEMEENRITGLSIALVDDQRVVWAEGFGKEDAERDVAAGPHTRYRMGSIAKVLTATA
HHCCCHHCCCCCEEEEEEECCCEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHH
AMQMAERGEIDIDRPLADYLPGFSVRSRFDDRTPITPRNIMHHHSGLPANYLKGMMGGDP
HHHHHHCCCCCCCCCHHHHCCCCCHHHCCCCCCCCCHHHHHHHCCCCCHHHHHHHCCCCC
PPFTTLVEAVREEYVAYPPEFIFGYSNLAVTLLGAALEQRAGLPFADHMAKSLIEPLGMT
CCHHHHHHHHHHHHCCCCCHHHCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCC
ETRFESNPALRVYDARGQIEALPLRDLPSGGLVSSVADMSRFMRMVFAGGRSGNTQLLRP
HHHCCCCCCEEEEECCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCEECH
ETLHEMLRAQNEHIALDLGFRVGLGWLLSGIEIRNAGLVASHGGTLFDSHSMMVVLPEHK
HHHHHHHHCCCCEEEEEECHHHHHHHHHCCCEEECCCEEEECCCEEEECCCEEEEECCCC
LGVIVASNSGTSQGTVKKIATEALIHALEAKAGIRQPEAAAIAQPEVRLAPEQLASYSAW
EEEEEECCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHCCCCCCEECHHHHHHHHHH
YDSMVGLIRVKPRAGALDADVMGHTLQLRAQPGGQFGLRYKLFGLIPVQVGAFDGVRISA
HHHCEEEEEECCCCCCCCHHHCCCEEEEEECCCCCCCEEEEEEEEEEEEECCCCCCEEEE
AAIGGHEVLVGHFGDDTMLVGEKLAPRPIPRTMLDYVGEYEIVGKPPGLAPDRLALRVED
EEECCCEEEEEECCCCEEEECCCCCCCCCCHHHHHHCCCEEEECCCCCCCCCCEEEEEEC
GMLIGECSFSELPGFMLRIALNPISPTEAVISGLGTGKGETIRILPGEGRRLLFSGLELR
CEEEEECCHHHCCCEEEEEEECCCCHHHHHHHHCCCCCCCEEEEECCCCCEEEECCHHHH
QKTN
HCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA