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The map label for this gene is darB [H]

Identifier: 119896583

GI number: 119896583

Start: 315826

End: 316980

Strand: Reverse

Name: darB [H]

Synonym: azo0292

Alternate gene names: 119896583

Gene position: 316980-315826 (Counterclockwise)

Preceding gene: 119896584

Following gene: 119896582

Centisome position: 7.24

GC content: 71.08

Gene sequence:

>1155_bases
ATGGCTGAGGCGCGCGCGGTCTACATCACCGCCACCGCGGCCTTCCTGCCCAACGCGCCGGTCGGCAACGACGACATCGA
GGCGGTGCTGGGCCGCATCGGCGGGCGGCCGTCGCGCGCGCGCCGCCTGGTGCTGCGCAACAACGGCATCGAAAGCCGCC
ACTACGCGATCGACCCCGCGAGCGGCGCCGCCACCCACACCAACGCCCAGCTCACCGCCGCCGCCGTCCGCGCGCTGGAA
GCGCCCGGCTTTGCGCTCGACACGCTGGAATGCCTTGTCACCGGCACCTCGCTGCCGGACCAGCTGATGCCCAATCATGG
CGTGATGGTGCACGGCGAACTCGGCACCCCGGCGTGCGAGGTCGTCTCCACCGCCGGCATCTGCCTCGCCGGCATGACCG
CGCTGAAGTACGCCTGGCTGTCGGTGCTGGCGGGCAACAGCCGCAACGCGGTCGCGAGCGGTTCCGAACTCGCCTCGGCG
GTGATGCGTGCGGCGCACTTCGAGGCCGAGAACGAGGCTCGCGTCGATGCGCTGGAGACGCACCCCGAGATCGCCTTCGA
GAAGGACTTCCTGCGCTGGATGCTGTCCGACGGCGCCGGTGCCTTCCTGCTGCAGGACGCGCCGCGGCCGGATGCGCCCT
CGCTGCGCATCGACTGGTTCGAGCTGTCCTCGCAGGCCCACGCCCAGCCCGCGTGCATGTACGCCGGCGCCGACAAGGAC
GCCGACGGCAGCCTGCGCGGGTGGGCGCGCTTCAGCGCCGCCGAATGGGGCCGGCGCTCCATCTTCGCGGTCAAGCAGGA
CGTCCGCCAGCTCAACGAACAGGTGGTGCGGCAGACCCTGGAAATCCCGCTCGCCAGCCTGATCGCCCGCCGCGGGCTGA
AGGCGGACGCGATCGACTGGTTCCTGCCGCACATGTCGTCCGCTTATTTCCGCCAACCGGTGGCAGACTGTCTGGCCCGG
CTCGGCTGCGCGATCCCGCCCGAGCGCTGGTTCACCAACCTCGCGCAGCGCGGCAACACCGGCTCGGCGTCCATCTTCAT
CATGCTCGACGAGCTGGTGCGCAGCGGCCGCCTGCGCCGCGGCCAGCGCCTGCTGTGCTTCGTGCCGGAAAGCGGCCGCT
TTTCCAGCGGCTTCCTCCACCTCACCGTGGTGTAA

Upstream 100 bases:

>100_bases
CTGCAGACGCTGTTCGCGCCGCTGCTGCGGGCGCGCCTGGAGCGCCTGCGCGCGCAGTACGAGCAACCCTCCGGCTCCGC
GGATTTCCGCCTGACCCGCA

Downstream 100 bases:

>100_bases
ACGAGGGCCGCGATGGATATCGACGACGTTCCGCAGGAAGGCAACCGCAGCCTCGGCGGCCACCGCAAGGCGCTCTACGC
GCGCGGCGCCGACGGCCAGC

Product: 3-oxoacyl-(acyl carrier protein) synthase III

Products: NA

Alternate protein names: 3-oxoacyl-[acyl-carrier-protein] synthase III; Beta-ketoacyl-ACP synthase III; KAS III [H]

Number of amino acids: Translated: 384; Mature: 383

Protein sequence:

>384_residues
MAEARAVYITATAAFLPNAPVGNDDIEAVLGRIGGRPSRARRLVLRNNGIESRHYAIDPASGAATHTNAQLTAAAVRALE
APGFALDTLECLVTGTSLPDQLMPNHGVMVHGELGTPACEVVSTAGICLAGMTALKYAWLSVLAGNSRNAVASGSELASA
VMRAAHFEAENEARVDALETHPEIAFEKDFLRWMLSDGAGAFLLQDAPRPDAPSLRIDWFELSSQAHAQPACMYAGADKD
ADGSLRGWARFSAAEWGRRSIFAVKQDVRQLNEQVVRQTLEIPLASLIARRGLKADAIDWFLPHMSSAYFRQPVADCLAR
LGCAIPPERWFTNLAQRGNTGSASIFIMLDELVRSGRLRRGQRLLCFVPESGRFSSGFLHLTVV

Sequences:

>Translated_384_residues
MAEARAVYITATAAFLPNAPVGNDDIEAVLGRIGGRPSRARRLVLRNNGIESRHYAIDPASGAATHTNAQLTAAAVRALE
APGFALDTLECLVTGTSLPDQLMPNHGVMVHGELGTPACEVVSTAGICLAGMTALKYAWLSVLAGNSRNAVASGSELASA
VMRAAHFEAENEARVDALETHPEIAFEKDFLRWMLSDGAGAFLLQDAPRPDAPSLRIDWFELSSQAHAQPACMYAGADKD
ADGSLRGWARFSAAEWGRRSIFAVKQDVRQLNEQVVRQTLEIPLASLIARRGLKADAIDWFLPHMSSAYFRQPVADCLAR
LGCAIPPERWFTNLAQRGNTGSASIFIMLDELVRSGRLRRGQRLLCFVPESGRFSSGFLHLTVV
>Mature_383_residues
AEARAVYITATAAFLPNAPVGNDDIEAVLGRIGGRPSRARRLVLRNNGIESRHYAIDPASGAATHTNAQLTAAAVRALEA
PGFALDTLECLVTGTSLPDQLMPNHGVMVHGELGTPACEVVSTAGICLAGMTALKYAWLSVLAGNSRNAVASGSELASAV
MRAAHFEAENEARVDALETHPEIAFEKDFLRWMLSDGAGAFLLQDAPRPDAPSLRIDWFELSSQAHAQPACMYAGADKDA
DGSLRGWARFSAAEWGRRSIFAVKQDVRQLNEQVVRQTLEIPLASLIARRGLKADAIDWFLPHMSSAYFRQPVADCLARL
GCAIPPERWFTNLAQRGNTGSASIFIMLDELVRSGRLRRGQRLLCFVPESGRFSSGFLHLTVV

Specific function: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the

COG id: COG0332

COG function: function code I; 3-oxoacyl-[acyl-carrier-protein] synthase III

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fabH family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013751
- InterPro:   IPR013747
- InterPro:   IPR004655
- InterPro:   IPR016039
- InterPro:   IPR016038 [H]

Pfam domain/function: PF08545 ACP_syn_III; PF08541 ACP_syn_III_C [H]

EC number: =2.3.1.180 [H]

Molecular weight: Translated: 41493; Mature: 41361

Theoretical pI: Translated: 6.99; Mature: 6.99

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAEARAVYITATAAFLPNAPVGNDDIEAVLGRIGGRPSRARRLVLRNNGIESRHYAIDPA
CCCCEEEEEEEEEHHCCCCCCCCHHHHHHHHHHCCCHHHHHEEEEECCCCCCCEEEECCC
SGAATHTNAQLTAAAVRALEAPGFALDTLECLVTGTSLPDQLMPNHGVMVHGELGTPACE
CCCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCHHHCCCCCEEEECCCCCCHHH
VVSTAGICLAGMTALKYAWLSVLAGNSRNAVASGSELASAVMRAAHFEAENEARVDALET
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCHHHHC
HPEIAFEKDFLRWMLSDGAGAFLLQDAPRPDAPSLRIDWFELSSQAHAQPACMYAGADKD
CCCHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCEEEEHEECCCCCCCCCEEEEECCCCC
ADGSLRGWARFSAAEWGRRSIFAVKQDVRQLNEQVVRQTLEIPLASLIARRGLKADAIDW
CCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCHHHHH
FLPHMSSAYFRQPVADCLARLGCAIPPERWFTNLAQRGNTGSASIFIMLDELVRSGRLRR
HHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCEEEEEEEHHHHHCCCCCC
GQRLLCFVPESGRFSSGFLHLTVV
CCEEEEEECCCCCCCCCEEEEEEC
>Mature Secondary Structure 
AEARAVYITATAAFLPNAPVGNDDIEAVLGRIGGRPSRARRLVLRNNGIESRHYAIDPA
CCCEEEEEEEEEHHCCCCCCCCHHHHHHHHHHCCCHHHHHEEEEECCCCCCCEEEECCC
SGAATHTNAQLTAAAVRALEAPGFALDTLECLVTGTSLPDQLMPNHGVMVHGELGTPACE
CCCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCHHHCCCCCEEEECCCCCCHHH
VVSTAGICLAGMTALKYAWLSVLAGNSRNAVASGSELASAVMRAAHFEAENEARVDALET
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCHHHHC
HPEIAFEKDFLRWMLSDGAGAFLLQDAPRPDAPSLRIDWFELSSQAHAQPACMYAGADKD
CCCHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCEEEEHEECCCCCCCCCEEEEECCCCC
ADGSLRGWARFSAAEWGRRSIFAVKQDVRQLNEQVVRQTLEIPLASLIARRGLKADAIDW
CCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCHHHHH
FLPHMSSAYFRQPVADCLARLGCAIPPERWFTNLAQRGNTGSASIFIMLDELVRSGRLRR
HHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCEEEEEEEHHHHHCCCCCC
GQRLLCFVPESGRFSSGFLHLTVV
CCEEEEEECCCCCCCCCEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA