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The map label for this gene is qseC [H]

Identifier: 119896554

GI number: 119896554

Start: 290292

End: 291683

Strand: Reverse

Name: qseC [H]

Synonym: azo0263

Alternate gene names: 119896554

Gene position: 291683-290292 (Counterclockwise)

Preceding gene: 119896555

Following gene: 119896553

Centisome position: 6.67

GC content: 75.0

Gene sequence:

>1392_bases
ATGAGCGCGGACGCGCTGCCGCTGCCCGGCTGGTCACTGAAGCGGCGGCTGCTCGGCCTGCTGCTGCTGGTGGCCGGCGG
CGTGTCGGCGCTGACCATCGTGCTCGCCTACCGCGCGGCCCACACCGAGGCCGAGCACGCCTTCGATGCGCAGCTGGTGG
TCGTGGCCGAAACCCTCATGGCGATCGCCGCCGACGCCGGGGTGGATTACGCCGAACACGAACTCTCGGAGCACGCCTAC
CCCGACACCCTGCCGGTGGCCTACCAGGTCTGGGGCCGCCAGGATGGCCGCGTCAGCCTGCTGCTGCGTTCCGCCAGCGC
GCCCGCCACCGCGATGACGGTGCACGAAGGCCTCAGCGACGGCGAGCGCGATGGCCGCCGTTGGCGCCATTACCTGCTGC
GGCGCGGCGACTTCGCGGTCATCGCGGGTCAGGACCATGCCGGGCGCGATGCGCTCGCGCGCGAACTCACGCTGCGCATC
CTGCTGCCCTTCCTCCTTGCGCTGCCGCTGCTCGCCGCGGCGATCTGGCTGACCGTGGGCCGCGCGCTGCAGCCGGTCGC
CGCGCTCGCGGCGGAAGTGGAAGCGATGAAGCCCGACGGGCTGAACCCGGTGGGCCTCGCCGATCCGCCGCCGCAGGAGA
TCGCCCCGCTGCTGCAGGCGCTCAACCGGCTGATCGGGCGAATGGCGGCCGCGCTCGCCGGCGAGCAGCGCTTCACCGCC
GACGCCGCCCACGAGCTGCGCACCCCGCTTGCCGCACTGCGCATCCAGGCCCAGGTGGCCGCCCGGGCCGGCGAGGACAG
TGCGGCGCGCGAGCGCGCGCTCGACCAGGTCATTGCCGGCGTGGACCGCATGACCCATCTGGTCGACCAGCTGCTGACGC
TGGCCCGGCTCGAACCCGCAGCCGCGCAGCCCGCCTTCGCCCCGGTCGACCTCGCGGCGGTGGCGGAGGCCGCGGTTGCA
GCGCTCGCCCCGCGCAGCGCCGCGCGCAAGCAACACGTGGAGTGCGCGCTGGCCCCCGCCACCGTCAGCGGCAACGCGGT
GTGGCTCGGCATCCTCGCCCGCAACCTCATCGACAACGCGTTGCGCTACGCGCCGCCGGGCAGCCACATCCGCGTGCGCA
CCGCGCGCGAAGGCATGCGCTGCGTGCTGGAAGTGAGCGACGACGGCCCCGGCCTGGAGCCCGGTGCGCGCGACAGCCTG
CGTGCGCGCTTTGCGCGCGGGGTGGCGGCGGACGGCGAAGGCTGCGGCCTCGGGCTGTCCATCGTCGGCCGCATCGTCGA
GCTGCACGGCGGCGAATTCCGCCTCGGCGACGGCCTGCCGCGCAGCGCGCCGGCCGGGGTGGGACTGGCCGCCACGGTGG
TGCTGGCCGCGGCAAGTCCCTCCCCACGCTAG

Upstream 100 bases:

>100_bases
CCGAGAGCAACACGCTGGAGGTCCACATCCACCACCTGCGGCGCAAGCTCGGCGCCGACCTCATCCACACCGTGCGCGGC
GTGGGCTACACGGTGCCGGC

Downstream 100 bases:

>100_bases
GGAAACTTTGCCGCAGGCGTTCAAAAATGCCGCCCGGCCGGTTAACATTGCGGGTTCCAGTCGTCGGTCCGCGTTAGCAT
GGACGGACGTTTCCGGCCTA

Product: two-component system histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 463; Mature: 462

Protein sequence:

>463_residues
MSADALPLPGWSLKRRLLGLLLLVAGGVSALTIVLAYRAAHTEAEHAFDAQLVVVAETLMAIAADAGVDYAEHELSEHAY
PDTLPVAYQVWGRQDGRVSLLLRSASAPATAMTVHEGLSDGERDGRRWRHYLLRRGDFAVIAGQDHAGRDALARELTLRI
LLPFLLALPLLAAAIWLTVGRALQPVAALAAEVEAMKPDGLNPVGLADPPPQEIAPLLQALNRLIGRMAAALAGEQRFTA
DAAHELRTPLAALRIQAQVAARAGEDSAARERALDQVIAGVDRMTHLVDQLLTLARLEPAAAQPAFAPVDLAAVAEAAVA
ALAPRSAARKQHVECALAPATVSGNAVWLGILARNLIDNALRYAPPGSHIRVRTAREGMRCVLEVSDDGPGLEPGARDSL
RARFARGVAADGEGCGLGLSIVGRIVELHGGEFRLGDGLPRSAPAGVGLAATVVLAAASPSPR

Sequences:

>Translated_463_residues
MSADALPLPGWSLKRRLLGLLLLVAGGVSALTIVLAYRAAHTEAEHAFDAQLVVVAETLMAIAADAGVDYAEHELSEHAY
PDTLPVAYQVWGRQDGRVSLLLRSASAPATAMTVHEGLSDGERDGRRWRHYLLRRGDFAVIAGQDHAGRDALARELTLRI
LLPFLLALPLLAAAIWLTVGRALQPVAALAAEVEAMKPDGLNPVGLADPPPQEIAPLLQALNRLIGRMAAALAGEQRFTA
DAAHELRTPLAALRIQAQVAARAGEDSAARERALDQVIAGVDRMTHLVDQLLTLARLEPAAAQPAFAPVDLAAVAEAAVA
ALAPRSAARKQHVECALAPATVSGNAVWLGILARNLIDNALRYAPPGSHIRVRTAREGMRCVLEVSDDGPGLEPGARDSL
RARFARGVAADGEGCGLGLSIVGRIVELHGGEFRLGDGLPRSAPAGVGLAATVVLAAASPSPR
>Mature_462_residues
SADALPLPGWSLKRRLLGLLLLVAGGVSALTIVLAYRAAHTEAEHAFDAQLVVVAETLMAIAADAGVDYAEHELSEHAYP
DTLPVAYQVWGRQDGRVSLLLRSASAPATAMTVHEGLSDGERDGRRWRHYLLRRGDFAVIAGQDHAGRDALARELTLRIL
LPFLLALPLLAAAIWLTVGRALQPVAALAAEVEAMKPDGLNPVGLADPPPQEIAPLLQALNRLIGRMAAALAGEQRFTAD
AAHELRTPLAALRIQAQVAARAGEDSAARERALDQVIAGVDRMTHLVDQLLTLARLEPAAAQPAFAPVDLAAVAEAAVAA
LAPRSAARKQHVECALAPATVSGNAVWLGILARNLIDNALRYAPPGSHIRVRTAREGMRCVLEVSDDGPGLEPGARDSLR
ARFARGVAADGEGCGLGLSIVGRIVELHGGEFRLGDGLPRSAPAGVGLAATVVLAAASPSPR

Specific function: Member of a two-component regulatory system qseB/qseC. May activate qseB by phosphorylation [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1789403, Length=438, Percent_Identity=33.1050228310502, Blast_Score=192, Evalue=3e-50,
Organism=Escherichia coli, GI1790551, Length=289, Percent_Identity=34.2560553633218, Blast_Score=143, Evalue=3e-35,
Organism=Escherichia coli, GI1788279, Length=289, Percent_Identity=27.681660899654, Blast_Score=95, Evalue=8e-21,
Organism=Escherichia coli, GI1786600, Length=213, Percent_Identity=32.8638497652582, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI1788393, Length=228, Percent_Identity=32.8947368421053, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI1786783, Length=268, Percent_Identity=26.4925373134328, Blast_Score=90, Evalue=4e-19,
Organism=Escherichia coli, GI1789808, Length=286, Percent_Identity=29.020979020979, Blast_Score=79, Evalue=8e-16,
Organism=Escherichia coli, GI1787894, Length=223, Percent_Identity=30.9417040358744, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1790346, Length=232, Percent_Identity=26.2931034482759, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1786912, Length=192, Percent_Identity=31.25, Blast_Score=74, Evalue=3e-14,
Organism=Escherichia coli, GI1790861, Length=271, Percent_Identity=28.4132841328413, Blast_Score=74, Evalue=3e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 48520; Mature: 48389

Theoretical pI: Translated: 6.66; Mature: 6.66

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSADALPLPGWSLKRRLLGLLLLVAGGVSALTIVLAYRAAHTEAEHAFDAQLVVVAETLM
CCCCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCHHHHHHCHHHHHHHHHHH
AIAADAGVDYAEHELSEHAYPDTLPVAYQVWGRQDGRVSLLLRSASAPATAMTVHEGLSD
HHHHHCCCCHHHHHHHHCCCCCCCCHHHHCCCCCCCEEEEEEECCCCCCHHHHHHHCCCC
GERDGRRWRHYLLRRGDFAVIAGQDHAGRDALARELTLRILLPFLLALPLLAAAIWLTVG
CHHHHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RALQPVAALAAEVEAMKPDGLNPVGLADPPPQEIAPLLQALNRLIGRMAAALAGEQRFTA
HHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHH
DAAHELRTPLAALRIQAQVAARAGEDSAARERALDQVIAGVDRMTHLVDQLLTLARLEPA
HHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
AAQPAFAPVDLAAVAEAAVAALAPRSAARKQHVECALAPATVSGNAVWLGILARNLIDNA
CCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHEEEECCEECCCCHHHHHHHHHHHHHH
LRYAPPGSHIRVRTAREGMRCVLEVSDDGPGLEPGARDSLRARFARGVAADGEGCGLGLS
HHCCCCCCCEEEEEHHCCCEEEEEECCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCHHH
IVGRIVELHGGEFRLGDGLPRSAPAGVGLAATVVLAAASPSPR
HHHHHHHHCCCCEEECCCCCCCCCCCCHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
SADALPLPGWSLKRRLLGLLLLVAGGVSALTIVLAYRAAHTEAEHAFDAQLVVVAETLM
CCCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCHHHHHHCHHHHHHHHHHH
AIAADAGVDYAEHELSEHAYPDTLPVAYQVWGRQDGRVSLLLRSASAPATAMTVHEGLSD
HHHHHCCCCHHHHHHHHCCCCCCCCHHHHCCCCCCCEEEEEEECCCCCCHHHHHHHCCCC
GERDGRRWRHYLLRRGDFAVIAGQDHAGRDALARELTLRILLPFLLALPLLAAAIWLTVG
CHHHHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RALQPVAALAAEVEAMKPDGLNPVGLADPPPQEIAPLLQALNRLIGRMAAALAGEQRFTA
HHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHH
DAAHELRTPLAALRIQAQVAARAGEDSAARERALDQVIAGVDRMTHLVDQLLTLARLEPA
HHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
AAQPAFAPVDLAAVAEAAVAALAPRSAARKQHVECALAPATVSGNAVWLGILARNLIDNA
CCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHEEEECCEECCCCHHHHHHHHHHHHHH
LRYAPPGSHIRVRTAREGMRCVLEVSDDGPGLEPGARDSLRARFARGVAADGEGCGLGLS
HHCCCCCCCEEEEEHHCCCEEEEEECCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCHHH
IVGRIVELHGGEFRLGDGLPRSAPAGVGLAATVVLAAASPSPR
HHHHHHHHCCCCEEECCCCCCCCCCCCHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800; 10675023 [H]