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The map label for this gene is fhuA1 [H]

Identifier: 119896520

GI number: 119896520

Start: 254346

End: 256517

Strand: Direct

Name: fhuA1 [H]

Synonym: azo0229

Alternate gene names: 119896520

Gene position: 254346-256517 (Clockwise)

Preceding gene: 119896519

Following gene: 119896521

Centisome position: 5.81

GC content: 66.02

Gene sequence:

>2172_bases
ATGACTACCAGGACCAAGCGTCGCCTCCGCCGCGTGCTCGTACCCGCGGCCGCCGCCCTCAGCTGTGCCTCGGTGTTTGC
CGCCGAACCCGCCGACACCCAGGACGCCGCCGACACCACGCCCGCTGCCGCGACCGCCTCCGCCAGCACGCTCGACACCG
TCAGCGTCACCGGCAAGAAGCAGCCCTACCGCAAGCTCACCGCTACCGGCGCCACCAAGACCGACACCCTGCTGAAGGAT
CTGCCGCAGAGCGTGCGCGTGCTGACCGAGGATCTGCTGGAAGACGCCGGCGTCACCAACCTCGCCGGCGCGCTGGACCT
TTCCAGCGGCGTGTCGCGCCAGAGCAACCTCGGCGGCCTGTGGGACAGCTACGCGATGCGCGGCTTCACCGGCGACCCCA
GCTTCGGCTCCGACTACCTGGTGAACGGCTTCAACTACAGCCGCGGCTACAACGGCGTGCGCGACGCCGCCAACACCGGC
TCGGTGGAAGTGCTGAAGGGGCCGTCGGCCGCGCTGTACGGCCGCGGTGAACCCGGCGGCACGGTGAACATCACCACCAA
GAAGCCGTTGTTCCAGCGCGAAGGCCAGGTGGACATCTCCTACGGCAGCTTCGACGCCTTCCGCACCGCGATCGACCTCA
CTGGCCCGATCTCCGACCGCATGGCCTACCGCCTCAACGGCGCCTACGAGAAGGCCGGCAGCTATCGCGACCACGTCTCG
TCGGAACGCTCGCTGATCTCGCCGTCCTTCCTGTGGATGCTGTCGGACGACACCACGCTGTCGTACGAGCTGGAAGTGTC
GCGCCAGAAGGCCACCTTCGATCGCGGCGTGATGGCGATCAACGGCAAGCTCGGCGTGCTGTCGCGCAAGCGCTTCCTCG
GCGAACCGGGCGATGGCGATCACGACACCGAGACCGTCGGCCACCAGGTCTTCCTGCAGCACTACCTCAACGACGACTGG
CAGCTGCAGGGGGGCTTCAGCTTCCGCGAAAGCTCGATCAAGGGCACCTCGACCGAAGTGCGCTTCCTGCGCGCCGACGG
CGAGAACGCGGCACGCCAGCGCCGCACCCGCGACAACGAGGCCTCCGATCTGTCCGCGCGCGCCGAGCTGCTCGGCAGCT
TCAGGACCGGCCCGCTCAAGCACAACGTGCTGTTCGGCGTCGATGCCTACAAGTTCGTCGACGAGCGCCTGCAGTACCGT
ATCGCCAACGCCGGCGACATCAACATCTTCGAGCCGGTGTACGGCAATGTGGTGTGGGGCTTCACGCCCGCCAACCGCAA
CACCGACACCAAGGAAGAGCAGGATTCGCGCAGCCTCTATGCGCAGGACCAGATCGACCTGACCGAGCAGTGGAAGCTGC
TGCTGGGCGTGCGCTTCGACGACTACGACCAGAAGCTGACCAACAACCGCAACGGCATCGTGGTGAAGAAGTCGCTCGCC
GCCACCAGCCCGCGCGTCGGCCTGGTGTATCAGCCGACCAAGCAGGTTTCGCTGTATGCCCAGGCGGGCAAGAGCTTCCG
CCCCAACGGCGGGGTGAGCCGCGACTTCACCGCCTTCGATCCGGAAGAGGGCCGCTCGTATGAACTGGGCGCCAAGTGGG
ATTCGGCCGACCAGCGCATCACGAGCACCGTCGCGCTGTTCCACATCACCAAGGAAAACGTGCTGAGTCCGGACCCGGTC
GACCCGAACAACTTCTACGTGACCGCCGGCGAAGTGGAAAGCAAGGGTCTGGAGTTCGACCTGTCCGGCGAGATCATGCC
GACCGTCCGCCTGTCCTTCGCCTACGCCTACACCAAGACCGAGGTCACCAAGGACAACAACAAGCTGCTGGAAGGCCGAG
AGCTGGCCAACGTGCCGCTGCACAGCGCCAACCTGATGCTGGTCAAGAGCCTGTCGCTGAACGACAAGCCGGCGACCGTC
GGCGTCGGCCTGAACTATGTCGGCGAACGCGAAGGCGCGGTGGCCCCGCTGGTTGCCGCCGACGACTTCAAGCTGCCCGG
CTACACCACGGTCAAGCTCACCGGCTCGTACAACTTCGACAAGCAGACCAAGCTGATGCTGGAGGTCGATAACCTCTTCG
ACAAGGAGTACTACACCAGCTCCTACAGCCAGGCCTGGGTCTATCCGGGCAGCCCGCGCGCCTTCAAGGCCACGCTGCAG
CACCGCTTCTGA

Upstream 100 bases:

>100_bases
TTTTTCGTACAAGACCGGACGCAGCGCATGGCCGATCCTTGATGCCGACACGATGTCTTGCCGCACCCCCATCCCCGTCT
GCCATCAGGAGTAGATCGAC

Downstream 100 bases:

>100_bases
TCGCCTGGGGAGAGTCCGAAAGATGAACCTGAAACCCGTGTTCCGCAGCCTCGCCGCCGGCCTCGCGCTGGCGGCCGTGG
CCGGCGCCGCTCACGCCCAC

Product: ferrichrome-iron TonB-dependent receptor

Products: NA

Alternate protein names: Ferric hydroxamate receptor; Ferric hydroxamate uptake [H]

Number of amino acids: Translated: 723; Mature: 722

Protein sequence:

>723_residues
MTTRTKRRLRRVLVPAAAALSCASVFAAEPADTQDAADTTPAAATASASTLDTVSVTGKKQPYRKLTATGATKTDTLLKD
LPQSVRVLTEDLLEDAGVTNLAGALDLSSGVSRQSNLGGLWDSYAMRGFTGDPSFGSDYLVNGFNYSRGYNGVRDAANTG
SVEVLKGPSAALYGRGEPGGTVNITTKKPLFQREGQVDISYGSFDAFRTAIDLTGPISDRMAYRLNGAYEKAGSYRDHVS
SERSLISPSFLWMLSDDTTLSYELEVSRQKATFDRGVMAINGKLGVLSRKRFLGEPGDGDHDTETVGHQVFLQHYLNDDW
QLQGGFSFRESSIKGTSTEVRFLRADGENAARQRRTRDNEASDLSARAELLGSFRTGPLKHNVLFGVDAYKFVDERLQYR
IANAGDINIFEPVYGNVVWGFTPANRNTDTKEEQDSRSLYAQDQIDLTEQWKLLLGVRFDDYDQKLTNNRNGIVVKKSLA
ATSPRVGLVYQPTKQVSLYAQAGKSFRPNGGVSRDFTAFDPEEGRSYELGAKWDSADQRITSTVALFHITKENVLSPDPV
DPNNFYVTAGEVESKGLEFDLSGEIMPTVRLSFAYAYTKTEVTKDNNKLLEGRELANVPLHSANLMLVKSLSLNDKPATV
GVGLNYVGEREGAVAPLVAADDFKLPGYTTVKLTGSYNFDKQTKLMLEVDNLFDKEYYTSSYSQAWVYPGSPRAFKATLQ
HRF

Sequences:

>Translated_723_residues
MTTRTKRRLRRVLVPAAAALSCASVFAAEPADTQDAADTTPAAATASASTLDTVSVTGKKQPYRKLTATGATKTDTLLKD
LPQSVRVLTEDLLEDAGVTNLAGALDLSSGVSRQSNLGGLWDSYAMRGFTGDPSFGSDYLVNGFNYSRGYNGVRDAANTG
SVEVLKGPSAALYGRGEPGGTVNITTKKPLFQREGQVDISYGSFDAFRTAIDLTGPISDRMAYRLNGAYEKAGSYRDHVS
SERSLISPSFLWMLSDDTTLSYELEVSRQKATFDRGVMAINGKLGVLSRKRFLGEPGDGDHDTETVGHQVFLQHYLNDDW
QLQGGFSFRESSIKGTSTEVRFLRADGENAARQRRTRDNEASDLSARAELLGSFRTGPLKHNVLFGVDAYKFVDERLQYR
IANAGDINIFEPVYGNVVWGFTPANRNTDTKEEQDSRSLYAQDQIDLTEQWKLLLGVRFDDYDQKLTNNRNGIVVKKSLA
ATSPRVGLVYQPTKQVSLYAQAGKSFRPNGGVSRDFTAFDPEEGRSYELGAKWDSADQRITSTVALFHITKENVLSPDPV
DPNNFYVTAGEVESKGLEFDLSGEIMPTVRLSFAYAYTKTEVTKDNNKLLEGRELANVPLHSANLMLVKSLSLNDKPATV
GVGLNYVGEREGAVAPLVAADDFKLPGYTTVKLTGSYNFDKQTKLMLEVDNLFDKEYYTSSYSQAWVYPGSPRAFKATLQ
HRF
>Mature_722_residues
TTRTKRRLRRVLVPAAAALSCASVFAAEPADTQDAADTTPAAATASASTLDTVSVTGKKQPYRKLTATGATKTDTLLKDL
PQSVRVLTEDLLEDAGVTNLAGALDLSSGVSRQSNLGGLWDSYAMRGFTGDPSFGSDYLVNGFNYSRGYNGVRDAANTGS
VEVLKGPSAALYGRGEPGGTVNITTKKPLFQREGQVDISYGSFDAFRTAIDLTGPISDRMAYRLNGAYEKAGSYRDHVSS
ERSLISPSFLWMLSDDTTLSYELEVSRQKATFDRGVMAINGKLGVLSRKRFLGEPGDGDHDTETVGHQVFLQHYLNDDWQ
LQGGFSFRESSIKGTSTEVRFLRADGENAARQRRTRDNEASDLSARAELLGSFRTGPLKHNVLFGVDAYKFVDERLQYRI
ANAGDINIFEPVYGNVVWGFTPANRNTDTKEEQDSRSLYAQDQIDLTEQWKLLLGVRFDDYDQKLTNNRNGIVVKKSLAA
TSPRVGLVYQPTKQVSLYAQAGKSFRPNGGVSRDFTAFDPEEGRSYELGAKWDSADQRITSTVALFHITKENVLSPDPVD
PNNFYVTAGEVESKGLEFDLSGEIMPTVRLSFAYAYTKTEVTKDNNKLLEGRELANVPLHSANLMLVKSLSLNDKPATVG
VGLNYVGEREGAVAPLVAADDFKLPGYTTVKLTGSYNFDKQTKLMLEVDNLFDKEYYTSSYSQAWVYPGSPRAFKATLQH
RF

Specific function: This receptor binds the ferrichrome-iron ligand. It interacts with the tonB protein, which is responsible for energy coupling of the ferrichrome-promoted iron transport system. Acts as a receptor for bacteriophage T5 as well as T1, phi80 and colicin M. Bi

COG id: COG1629

COG function: function code P; Outer membrane receptor proteins, mostly Fe transport

Gene ontology:

Cell location: Cell outer membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tonB-dependent receptor family [H]

Homologues:

Organism=Escherichia coli, GI1786344, Length=770, Percent_Identity=27.4025974025974, Blast_Score=207, Evalue=1e-54,
Organism=Escherichia coli, GI1787024, Length=708, Percent_Identity=24.7175141242938, Blast_Score=145, Evalue=1e-35,
Organism=Escherichia coli, GI1787344, Length=736, Percent_Identity=26.2228260869565, Blast_Score=140, Evalue=2e-34,
Organism=Escherichia coli, GI1790743, Length=367, Percent_Identity=25.0681198910082, Blast_Score=81, Evalue=3e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012910
- InterPro:   IPR000531
- InterPro:   IPR010916
- InterPro:   IPR010917
- InterPro:   IPR010105 [H]

Pfam domain/function: PF07715 Plug; PF00593 TonB_dep_Rec [H]

EC number: NA

Molecular weight: Translated: 79493; Mature: 79362

Theoretical pI: Translated: 6.18; Mature: 6.18

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS00430 TONB_DEPENDENT_REC_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.1 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.1 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTRTKRRLRRVLVPAAAALSCASVFAAEPADTQDAADTTPAAATASASTLDTVSVTGKK
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCC
QPYRKLTATGATKTDTLLKDLPQSVRVLTEDLLEDAGVTNLAGALDLSSGVSRQSNLGGL
CCCHHHEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCCCCCCCCCCC
WDSYAMRGFTGDPSFGSDYLVNGFNYSRGYNGVRDAANTGSVEVLKGPSAALYGRGEPGG
HHHHHHCCCCCCCCCCCCCEECCCCCCCCCCCHHCCCCCCCEEEEECCCEEEEECCCCCC
TVNITTKKPLFQREGQVDISYGSFDAFRTAIDLTGPISDRMAYRLNGAYEKAGSYRDHVS
EEEEEECCCHHHCCCEEEEEECCHHHHHHEEECCCCCCCCEEEEECCHHHHCCCHHHHHC
SERSLISPSFLWMLSDDTTLSYELEVSRQKATFDRGVMAINGKLGVLSRKRFLGEPGDGD
CCCCCCCCEEEEEEECCCEEEEEEEECCHHHHHHCCEEEECCCEEEEEHHHHCCCCCCCC
HDTETVGHQVFLQHYLNDDWQLQGGFSFRESSIKGTSTEVRFLRADGENAARQRRTRDNE
CCHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCCCEEEEEEECCCHHHHHHHCCCCC
ASDLSARAELLGSFRTGPLKHNVLFGVDAYKFVDERLQYRIANAGDINIFEPVYGNVVWG
HHHHHHHHHHHHCCCCCCCCCCEEECCHHHHHHHHHHHEEECCCCCCEEECCCCCCEEEE
FTPANRNTDTKEEQDSRSLYAQDQIDLTEQWKLLLGVRFDDYDQKLTNNRNGIVVKKSLA
EECCCCCCCCCHHHHHHHEEECCCCCHHHHEEEEEEEEECCHHHHHHCCCCCEEEEECCC
ATSPRVGLVYQPTKQVSLYAQAGKSFRPNGGVSRDFTAFDPEEGRSYELGAKWDSADQRI
CCCCCEEEEECCCHHEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCEECCCCCCCHHHHH
TSTVALFHITKENVLSPDPVDPNNFYVTAGEVESKGLEFDLSGEIMPTVRLSFAYAYTKT
HEEEEEEEEEHHCCCCCCCCCCCCEEEEECCCCCCCEEEEECCCEEEEEEEEEEEEEEEE
EVTKDNNKLLEGRELANVPLHSANLMLVKSLSLNDKPATVGVGLNYVGEREGAVAPLVAA
EEECCCCCEECCCHHCCCCCCCCCEEEEEECCCCCCCCEEEECCCCCCCCCCCEEEEEEC
DDFKLPGYTTVKLTGSYNFDKQTKLMLEVDNLFDKEYYTSSYSQAWVYPGSPRAFKATLQ
CCCCCCCEEEEEEEECCCCCCCEEEEEEEHHHHCHHHHCCCCCEEEEECCCCHHHHHHHH
HRF
CCC
>Mature Secondary Structure 
TTRTKRRLRRVLVPAAAALSCASVFAAEPADTQDAADTTPAAATASASTLDTVSVTGKK
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCC
QPYRKLTATGATKTDTLLKDLPQSVRVLTEDLLEDAGVTNLAGALDLSSGVSRQSNLGGL
CCCHHHEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCCCCCCCCCCC
WDSYAMRGFTGDPSFGSDYLVNGFNYSRGYNGVRDAANTGSVEVLKGPSAALYGRGEPGG
HHHHHHCCCCCCCCCCCCCEECCCCCCCCCCCHHCCCCCCCEEEEECCCEEEEECCCCCC
TVNITTKKPLFQREGQVDISYGSFDAFRTAIDLTGPISDRMAYRLNGAYEKAGSYRDHVS
EEEEEECCCHHHCCCEEEEEECCHHHHHHEEECCCCCCCCEEEEECCHHHHCCCHHHHHC
SERSLISPSFLWMLSDDTTLSYELEVSRQKATFDRGVMAINGKLGVLSRKRFLGEPGDGD
CCCCCCCCEEEEEEECCCEEEEEEEECCHHHHHHCCEEEECCCEEEEEHHHHCCCCCCCC
HDTETVGHQVFLQHYLNDDWQLQGGFSFRESSIKGTSTEVRFLRADGENAARQRRTRDNE
CCHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCCCEEEEEEECCCHHHHHHHCCCCC
ASDLSARAELLGSFRTGPLKHNVLFGVDAYKFVDERLQYRIANAGDINIFEPVYGNVVWG
HHHHHHHHHHHHCCCCCCCCCCEEECCHHHHHHHHHHHEEECCCCCCEEECCCCCCEEEE
FTPANRNTDTKEEQDSRSLYAQDQIDLTEQWKLLLGVRFDDYDQKLTNNRNGIVVKKSLA
EECCCCCCCCCHHHHHHHEEECCCCCHHHHEEEEEEEEECCHHHHHHCCCCCEEEEECCC
ATSPRVGLVYQPTKQVSLYAQAGKSFRPNGGVSRDFTAFDPEEGRSYELGAKWDSADQRI
CCCCCEEEEECCCHHEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCEECCCCCCCHHHHH
TSTVALFHITKENVLSPDPVDPNNFYVTAGEVESKGLEFDLSGEIMPTVRLSFAYAYTKT
HEEEEEEEEEHHCCCCCCCCCCCCEEEEECCCCCCCEEEEECCCEEEEEEEEEEEEEEEE
EVTKDNNKLLEGRELANVPLHSANLMLVKSLSLNDKPATVGVGLNYVGEREGAVAPLVAA
EEECCCCCEECCCHHCCCCCCCCCEEEEEECCCCCCCCEEEECCCCCCCCCCCEEEEEEC
DDFKLPGYTTVKLTGSYNFDKQTKLMLEVDNLFDKEYYTSSYSQAWVYPGSPRAFKATLQ
CCCCCCCEEEEEEEECCCCCCCEEEEEEEHHHHCHHHHCCCCCEEEEECCCCHHHHHHHH
HRF
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 3079747; 8202364; 9278503; 2823072; 7515827; 8617231; 9856937; 9865695; 10850805 [H]