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The map label for this gene is hipO1 [H]

Identifier: 119896496

GI number: 119896496

Start: 226835

End: 228079

Strand: Reverse

Name: hipO1 [H]

Synonym: azo0205

Alternate gene names: 119896496

Gene position: 228079-226835 (Counterclockwise)

Preceding gene: 119896497

Following gene: 119896495

Centisome position: 5.21

GC content: 72.69

Gene sequence:

>1245_bases
ATGAGCGCCGCCGCCCGGCCGTCCGCTGGGGGTGCCTCCTCCCCTGGTGAGGATGTCGCGCAGCGACAGGAGGGCAGTTC
GGAGAACATCGCCGACGACGCGCTCGCCGGCCTGCTGCCCGCGCTGGTCCGCCTGCGCCACGACCTCCACGCTCATCCCG
AACTCGGCTTCGCCGAGCATCGCACCGCGGCCGTGGTGGCCGCCGAACTGCGCGCCATCGGCCTCGCAGTGCACGAAGGC
ATCGGCGGCACCGGCGTGGTCGGCGTGCTGCGCAGGGGCAGCAGCGGCGCCAGCGTCGGCCTGCGCGCCGACATGGATGC
ACTGCCGATGGACGAATGCAGCGGTGTCGCCTACGCCAGCACTCACGCCGGCGCCCACCACGGCTGCGGCCACGACGGCC
ACACCAGCATGCTGCTCGGCGCGGCGCGCCTGCTCGCCGCGCGCGACTTCGACGGCACGGTGAACTTCATCTTCCAGCCC
GCCGAGGAAGGCCTGGGCGGCGCCCGCGCGATGGTGGAGGACGGCCTCTTCGAGCGCTTCCCCTGCGATGCGGTGTACGC
CCTGCACAACTGGCCGGCGCTGCCGCTGGGCACGGCGCAGACGCGGCCGGGGCCGATCATGGCGGCGGCCGACCGCTTCG
ACATCGTCATCCGCGGCCGCGGCGGCCATGCGGCGCAACCGCACACCACGCCGGACGCCATCCTCGCCGCCGGCCATCTG
GTCAGCCAGCTGCACGCCATCGTGTCGCGCCGCATCGACCCGGTGGAATCCGCGGTGCTGTCGATCACCCGCATCGAGAG
CGGCCACACCCACAACGTGCTGCCGGCCGAGGTGAAGCTGACCGGCACGGTGCGCAGCTTCGACCCGGCGGCGCAGGACA
CGATCGAGGCCGCGCTGCACCAGATCGCCGACGGCGTGGCGCTGGCGAGCGGCACCACCATCGCCATCGACTACCTGCGT
TACTACCCGGCAACCATCAACCACGCCGCCGAAGCACAGGTGGCGCTGGAAGCCGCAGCCAACGCCGGTCTGCAGGTGAA
AACCGCGCCGGCGCCCGCCTTCACCTCGGAAGACTTCGCCTTCATGCTGCAGGCCCGGCCCGGCGCCTACCTGTGGCTGG
GCCAGGGCCGCGGCGGCGACGACAAGCCGCTGCATCATCCCGCGTACGACTTCAACGACGCCGCGCTGCCGCACGGGGTG
CGCTGGCTGGTGGCGGTGGCGGAACGGCAATTGCAGCGCCGCTGA

Upstream 100 bases:

>100_bases
GCATGACGCCCAAGCAGTACCTGCGCGAAGCCGGGCCGCTGCCGGAAGGCGCCTACATCGGCGCGCTGCGCCAGCCCGCC
GCCTTTGCGGCCCACGCCGC

Downstream 100 bases:

>100_bases
CGCCCGGGCGCGAGGCGGCGTGCCGCTTATGGTGGCTATTCACGAATCGTGATCGCCCTGCGTGAGCGCGCGGCTAAGAT
GGCGGCATCCCCCGCGCGCC

Product: hippurate hydrolase

Products: NA

Alternate protein names: Benzoylglycine amidohydrolase; Hippuricase [H]

Number of amino acids: Translated: 414; Mature: 413

Protein sequence:

>414_residues
MSAAARPSAGGASSPGEDVAQRQEGSSENIADDALAGLLPALVRLRHDLHAHPELGFAEHRTAAVVAAELRAIGLAVHEG
IGGTGVVGVLRRGSSGASVGLRADMDALPMDECSGVAYASTHAGAHHGCGHDGHTSMLLGAARLLAARDFDGTVNFIFQP
AEEGLGGARAMVEDGLFERFPCDAVYALHNWPALPLGTAQTRPGPIMAAADRFDIVIRGRGGHAAQPHTTPDAILAAGHL
VSQLHAIVSRRIDPVESAVLSITRIESGHTHNVLPAEVKLTGTVRSFDPAAQDTIEAALHQIADGVALASGTTIAIDYLR
YYPATINHAAEAQVALEAAANAGLQVKTAPAPAFTSEDFAFMLQARPGAYLWLGQGRGGDDKPLHHPAYDFNDAALPHGV
RWLVAVAERQLQRR

Sequences:

>Translated_414_residues
MSAAARPSAGGASSPGEDVAQRQEGSSENIADDALAGLLPALVRLRHDLHAHPELGFAEHRTAAVVAAELRAIGLAVHEG
IGGTGVVGVLRRGSSGASVGLRADMDALPMDECSGVAYASTHAGAHHGCGHDGHTSMLLGAARLLAARDFDGTVNFIFQP
AEEGLGGARAMVEDGLFERFPCDAVYALHNWPALPLGTAQTRPGPIMAAADRFDIVIRGRGGHAAQPHTTPDAILAAGHL
VSQLHAIVSRRIDPVESAVLSITRIESGHTHNVLPAEVKLTGTVRSFDPAAQDTIEAALHQIADGVALASGTTIAIDYLR
YYPATINHAAEAQVALEAAANAGLQVKTAPAPAFTSEDFAFMLQARPGAYLWLGQGRGGDDKPLHHPAYDFNDAALPHGV
RWLVAVAERQLQRR
>Mature_413_residues
SAAARPSAGGASSPGEDVAQRQEGSSENIADDALAGLLPALVRLRHDLHAHPELGFAEHRTAAVVAAELRAIGLAVHEGI
GGTGVVGVLRRGSSGASVGLRADMDALPMDECSGVAYASTHAGAHHGCGHDGHTSMLLGAARLLAARDFDGTVNFIFQPA
EEGLGGARAMVEDGLFERFPCDAVYALHNWPALPLGTAQTRPGPIMAAADRFDIVIRGRGGHAAQPHTTPDAILAAGHLV
SQLHAIVSRRIDPVESAVLSITRIESGHTHNVLPAEVKLTGTVRSFDPAAQDTIEAALHQIADGVALASGTTIAIDYLRY
YPATINHAAEAQVALEAAANAGLQVKTAPAPAFTSEDFAFMLQARPGAYLWLGQGRGGDDKPLHHPAYDFNDAALPHGVR
WLVAVAERQLQRR

Specific function: Required But Not Essential For Aminobenzoyl-Glutamate Utilization. May Participate In Hydrolysis Of Aminobenzoyl- Glutamate To Aminobenzoate, Either Alone Or In Combination With Abgb. [C]

COG id: COG1473

COG function: function code R; Metal-dependent amidase/aminoacylase/carboxypeptidase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M20 family [H]

Homologues:

Organism=Escherichia coli, GI87081880, Length=240, Percent_Identity=34.1666666666667, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI1787598, Length=348, Percent_Identity=25.5747126436782, Blast_Score=63, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017439
- InterPro:   IPR010168
- InterPro:   IPR002933
- InterPro:   IPR011650 [H]

Pfam domain/function: PF07687 M20_dimer; PF01546 Peptidase_M20 [H]

EC number: =3.5.1.32 [H]

Molecular weight: Translated: 43234; Mature: 43103

Theoretical pI: Translated: 6.28; Mature: 6.28

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAAARPSAGGASSPGEDVAQRQEGSSENIADDALAGLLPALVRLRHDLHAHPELGFAEH
CCCCCCCCCCCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHH
RTAAVVAAELRAIGLAVHEGIGGTGVVGVLRRGSSGASVGLRADMDALPMDECSGVAYAS
HHHHHHHHHHHHHHHHHHCCCCCCCHHHHHCCCCCCCCCCEECCCCCCCHHHHCCCEEEC
THAGAHHGCGHDGHTSMLLGAARLLAARDFDGTVNFIFQPAEEGLGGARAMVEDGLFERF
CCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCEEEEEECHHHCCCHHHHHHHHCCHHHC
PCDAVYALHNWPALPLGTAQTRPGPIMAAADRFDIVIRGRGGHAAQPHTTPDAILAAGHL
CCHHHHHHHCCCCCCCCCCCCCCCCEEEECCCEEEEEECCCCCCCCCCCCHHHHHHHHHH
VSQLHAIVSRRIDPVESAVLSITRIESGHTHNVLPAEVKLTGTVRSFDPAAQDTIEAALH
HHHHHHHHHHCCCHHHHHHHHHHEECCCCCCCCCCCEEEEEEECCCCCCHHHHHHHHHHH
QIADGVALASGTTIAIDYLRYYPATINHAAEAQVALEAAANAGLQVKTAPAPAFTSEDFA
HHHCCEEECCCCEEEEHHHHHCCHHHCCHHHHHHHHHHHHCCCEEEEECCCCCCCCCCEE
FMLQARPGAYLWLGQGRGGDDKPLHHPAYDFNDAALPHGVRWLVAVAERQLQRR
EEEEECCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SAAARPSAGGASSPGEDVAQRQEGSSENIADDALAGLLPALVRLRHDLHAHPELGFAEH
CCCCCCCCCCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHH
RTAAVVAAELRAIGLAVHEGIGGTGVVGVLRRGSSGASVGLRADMDALPMDECSGVAYAS
HHHHHHHHHHHHHHHHHHCCCCCCCHHHHHCCCCCCCCCCEECCCCCCCHHHHCCCEEEC
THAGAHHGCGHDGHTSMLLGAARLLAARDFDGTVNFIFQPAEEGLGGARAMVEDGLFERF
CCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCEEEEEECHHHCCCHHHHHHHHCCHHHC
PCDAVYALHNWPALPLGTAQTRPGPIMAAADRFDIVIRGRGGHAAQPHTTPDAILAAGHL
CCHHHHHHHCCCCCCCCCCCCCCCCEEEECCCEEEEEECCCCCCCCCCCCHHHHHHHHHH
VSQLHAIVSRRIDPVESAVLSITRIESGHTHNVLPAEVKLTGTVRSFDPAAQDTIEAALH
HHHHHHHHHHCCCHHHHHHHHHHEECCCCCCCCCCCEEEEEEECCCCCCHHHHHHHHHHH
QIADGVALASGTTIAIDYLRYYPATINHAAEAQVALEAAANAGLQVKTAPAPAFTSEDFA
HHHCCEEECCCCEEEEHHHHHCCHHHCCHHHHHHHHHHHHCCCEEEEECCCCCCCCCCEE
FMLQARPGAYLWLGQGRGGDDKPLHHPAYDFNDAALPHGVRWLVAVAERQLQRR
EEEEECCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7730270; 10688204 [H]