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The map label for this gene is pabB [H]

Identifier: 119896489

GI number: 119896489

Start: 216106

End: 217965

Strand: Reverse

Name: pabB [H]

Synonym: azo0198

Alternate gene names: 119896489

Gene position: 217965-216106 (Counterclockwise)

Preceding gene: 119896492

Following gene: 119896487

Centisome position: 4.98

GC content: 73.44

Gene sequence:

>1860_bases
ATGGAAAGCTTTGCCCTGCTCGATGACAGCCAGGCCGCCGTGGAGACCCCCGCGAGCCGCCTCTATACCGGTTTTTGCGG
CGAGATCCGCTGTACCGATCCGGACCGCCTGGAGGCGGACTGGGTGCGGGTGGAAACGGAGCTGGCGGCGGGCCGTCACG
CGGTGATCGTGGCCGACTACGAATGGGGCGTGCGCCTGGCCGGCGTGACCACCGCCAAGCCGGGCGGGATGCTGCGGGTG
CTGCTGTATGCGACCCTGCAGCGGCTGGACGGCGCCGGCGTGGCGCACTGGCTGGCGCAGCAGGAAGGCCGGGACGAGCC
GGACGCCGCCGGCGTCGCCGAGTGGCAGGCTTCGCTTGAGCGGCCGGCGTTCGACGCGGCGATCGAGGCGATCCATGCCG
CGATCCGCGCCGGAGAAACCTATCAGATCAACTTCAGCTACCGCCTGGGCGGGCGCGCCTACGGGTCGCCGCTGGCGCTC
TACCGCCGCCTGCGCGCCGCGCAGCCGGTGCCCTTCGGCGCGCTGATCCGGCTGCCGGCGCCGACGGGAGACGGCGACGG
CGACGGCGGCTACCTGCTGTCGTGCTCGCCCGAGTTGTTCCTGCGCCACCGGGACGGCGTGCTGGAGGCGCGGCCGATGA
AGGGCACCGCCGCACGCCGCGGCGATCCCGCCGCCGACGCGCAGGCCGCGGGCGACCTTGCCGCGGACCCGAAGAACCGC
GCCGAGAACCTGATGATCGTCGACTTGCTGCGCAACGACCTCGGCCGCATCGCCGAAACCGGCAGCGTGCAGGTGCCGGC
GCTGTTCGCGGTCGAGCCCTATGCGACAGTGCTGCAGATGACGTCCACCGTCAGCGCGCGCCTTGCCGCCCGGCACGCGT
TTCCCGCGGTGCTGCGGGCGCTCTTTCCCTGCGGTTCGATCACCGGCGCGCCCAAGCACCGCAGCATGCGACTGATCGAC
ACGCTCGAGGACCGACCGCGCGGCACCTACACCGGCGCGGTCGGCTGGATGGACGCCCCCCGCGCCGGGCACCGCTGCGG
TGATTTCTGCCTGTCGGTGGCGATCCGCACGCTGGCAGTGGGCGCGGAGCGCGACGGCCGTCGCACCGCCGAGCTGGGCG
TCGGCGCCGGCATCGTCATCGACAGCCGGGCGGCGGACGAATACGCGGAATGCCAGCTGAAGGCGCGCTTCGTCACCGCG
CTCGACCCCGGCTTCCAGCTGATCGAAACGATGCGCGCGGGCCCTGCCGGAAGCGGTGGCGCGCCCGGGATTCCCCTGCT
GGCGCGCCACCTCGCGCGGCTCGCCGCAAGCGCCGCGGCGCTCGGCTTCCGATACGACGACGCGCAGGTACGCGCGGCGC
TGGCGCGGCATCTCGCGACGCTGGCGGACGGGATGCACCGCGTGCGCCTGCTGCTGCACAAGGACGGCCGCATCGACGTG
AGCGGCGGCCCGCTGCCAGCGCTGCCGCCGGGCCCGGTGCGCGTGCTGCTGGCCGACGCGCCGATCGACGGCCGCGACTA
CCTGCTGCGCCACAAGACCACCCGGCGCGCAAGCTACGACGCGGCGATCCGCGCAGCGGAGGCCGCCGGTGCGTTCGACA
CCCTGTTCTTCAACCACGCCGGCGCGTTGACCGAGGGCGGGCGCAGCAACGTATTCGTGCGCATGGACGGGCAATGGCTG
ACGCCGCCGGTGGAGGCGGGCGTGCTGCCCGGCGTGATGCGCGCGGCGCTGCTCGACGACCCCGCGTGGCAGGCGCACGA
AGCTGCACTGACGCGCGCGGACCTGGCGCGCGCCGAGGCGGTGGTGCTGTGCAATGCGTTGCGCGGCGTGCTTCACGTGC
GCTTCGATCAACGCGGGTAG

Upstream 100 bases:

>100_bases
GTGGAGAAAACGCATGCGGAAATCCTCAGGCGCGGAAGCGGAAAAACGGTGGAGTGTCGCACGGCGCGGCCGCGCACCGG
CCCGCCGCTAGAATGCCGCG

Downstream 100 bases:

>100_bases
GCGCGCCAAGCCGGCATCCCGCCTTGACGCAGGCGGCGCAGCGCCCGGCACAGCGCCCACACCAGCGCGCCGGCGCTCAG
TTCCAGCACGACGAGCGTCG

Product: para-aminobenzoate synthase component I

Products: NA

Alternate protein names: ADC synthase; Para-aminobenzoate synthase component I [H]

Number of amino acids: Translated: 619; Mature: 619

Protein sequence:

>619_residues
MESFALLDDSQAAVETPASRLYTGFCGEIRCTDPDRLEADWVRVETELAAGRHAVIVADYEWGVRLAGVTTAKPGGMLRV
LLYATLQRLDGAGVAHWLAQQEGRDEPDAAGVAEWQASLERPAFDAAIEAIHAAIRAGETYQINFSYRLGGRAYGSPLAL
YRRLRAAQPVPFGALIRLPAPTGDGDGDGGYLLSCSPELFLRHRDGVLEARPMKGTAARRGDPAADAQAAGDLAADPKNR
AENLMIVDLLRNDLGRIAETGSVQVPALFAVEPYATVLQMTSTVSARLAARHAFPAVLRALFPCGSITGAPKHRSMRLID
TLEDRPRGTYTGAVGWMDAPRAGHRCGDFCLSVAIRTLAVGAERDGRRTAELGVGAGIVIDSRAADEYAECQLKARFVTA
LDPGFQLIETMRAGPAGSGGAPGIPLLARHLARLAASAAALGFRYDDAQVRAALARHLATLADGMHRVRLLLHKDGRIDV
SGGPLPALPPGPVRVLLADAPIDGRDYLLRHKTTRRASYDAAIRAAEAAGAFDTLFFNHAGALTEGGRSNVFVRMDGQWL
TPPVEAGVLPGVMRAALLDDPAWQAHEAALTRADLARAEAVVLCNALRGVLHVRFDQRG

Sequences:

>Translated_619_residues
MESFALLDDSQAAVETPASRLYTGFCGEIRCTDPDRLEADWVRVETELAAGRHAVIVADYEWGVRLAGVTTAKPGGMLRV
LLYATLQRLDGAGVAHWLAQQEGRDEPDAAGVAEWQASLERPAFDAAIEAIHAAIRAGETYQINFSYRLGGRAYGSPLAL
YRRLRAAQPVPFGALIRLPAPTGDGDGDGGYLLSCSPELFLRHRDGVLEARPMKGTAARRGDPAADAQAAGDLAADPKNR
AENLMIVDLLRNDLGRIAETGSVQVPALFAVEPYATVLQMTSTVSARLAARHAFPAVLRALFPCGSITGAPKHRSMRLID
TLEDRPRGTYTGAVGWMDAPRAGHRCGDFCLSVAIRTLAVGAERDGRRTAELGVGAGIVIDSRAADEYAECQLKARFVTA
LDPGFQLIETMRAGPAGSGGAPGIPLLARHLARLAASAAALGFRYDDAQVRAALARHLATLADGMHRVRLLLHKDGRIDV
SGGPLPALPPGPVRVLLADAPIDGRDYLLRHKTTRRASYDAAIRAAEAAGAFDTLFFNHAGALTEGGRSNVFVRMDGQWL
TPPVEAGVLPGVMRAALLDDPAWQAHEAALTRADLARAEAVVLCNALRGVLHVRFDQRG
>Mature_619_residues
MESFALLDDSQAAVETPASRLYTGFCGEIRCTDPDRLEADWVRVETELAAGRHAVIVADYEWGVRLAGVTTAKPGGMLRV
LLYATLQRLDGAGVAHWLAQQEGRDEPDAAGVAEWQASLERPAFDAAIEAIHAAIRAGETYQINFSYRLGGRAYGSPLAL
YRRLRAAQPVPFGALIRLPAPTGDGDGDGGYLLSCSPELFLRHRDGVLEARPMKGTAARRGDPAADAQAAGDLAADPKNR
AENLMIVDLLRNDLGRIAETGSVQVPALFAVEPYATVLQMTSTVSARLAARHAFPAVLRALFPCGSITGAPKHRSMRLID
TLEDRPRGTYTGAVGWMDAPRAGHRCGDFCLSVAIRTLAVGAERDGRRTAELGVGAGIVIDSRAADEYAECQLKARFVTA
LDPGFQLIETMRAGPAGSGGAPGIPLLARHLARLAASAAALGFRYDDAQVRAALARHLATLADGMHRVRLLLHKDGRIDV
SGGPLPALPPGPVRVLLADAPIDGRDYLLRHKTTRRASYDAAIRAAEAAGAFDTLFFNHAGALTEGGRSNVFVRMDGQWL
TPPVEAGVLPGVMRAALLDDPAWQAHEAALTRADLARAEAVVLCNALRGVLHVRFDQRG

Specific function: Catalyzes the biosynthesis of 4-amino-4-deoxychorismate (ADC) from chorismate and glutamine [H]

COG id: COG0147

COG function: function code EH; Anthranilate/para-aminobenzoate synthases component I

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anthranilate synthase component I family [H]

Homologues:

Organism=Escherichia coli, GI1788114, Length=295, Percent_Identity=37.2881355932203, Blast_Score=197, Evalue=1e-51,
Organism=Escherichia coli, GI1787518, Length=285, Percent_Identity=35.0877192982456, Blast_Score=113, Evalue=3e-26,
Organism=Escherichia coli, GI1786809, Length=235, Percent_Identity=25.531914893617, Blast_Score=65, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6320935, Length=283, Percent_Identity=30.7420494699647, Blast_Score=122, Evalue=2e-28,
Organism=Saccharomyces cerevisiae, GI6324361, Length=286, Percent_Identity=29.3706293706294, Blast_Score=101, Evalue=4e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005801
- InterPro:   IPR019999
- InterPro:   IPR006805
- InterPro:   IPR015890
- InterPro:   IPR005802 [H]

Pfam domain/function: PF04715 Anth_synt_I_N; PF00425 Chorismate_bind [H]

EC number: =2.6.1.85 [H]

Molecular weight: Translated: 66027; Mature: 66027

Theoretical pI: Translated: 7.22; Mature: 7.22

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MESFALLDDSQAAVETPASRLYTGFCGEIRCTDPDRLEADWVRVETELAAGRHAVIVADY
CCCCEECCCCCHHHHCCHHHHHHCCCCCEECCCCCCCCCHHEEEEHHHCCCCEEEEEEEC
EWGVRLAGVTTAKPGGMLRVLLYATLQRLDGAGVAHWLAQQEGRDEPDAAGVAEWQASLE
CCCEEEEEEEECCCCCHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCCHHHHHHHHC
RPAFDAAIEAIHAAIRAGETYQINFSYRLGGRAYGSPLALYRRLRAAQPVPFGALIRLPA
CCHHHHHHHHHHHHHHCCCEEEEEEEEEECCCCCCCHHHHHHHHHHCCCCCCCEEEEECC
PTGDGDGDGGYLLSCSPELFLRHRDGVLEARPMKGTAARRGDPAADAQAAGDLAADPKNR
CCCCCCCCCCEEEEECHHHHHEECCCCCCCCCCCCCCCCCCCCCCCHHHCCCCCCCCCHH
AENLMIVDLLRNDLGRIAETGSVQVPALFAVEPYATVLQMTSTVSARLAARHAFPAVLRA
HCCEEEHHHHHHHHHHHHCCCCEECCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LFPCGSITGAPKHRSMRLIDTLEDRPRGTYTGAVGWMDAPRAGHRCGDFCLSVAIRTLAV
HHCCCCCCCCCCCCCCHHHHHHCCCCCCCEECCCCCCCCCCCCCHHHHHHHHHHHHHHHC
GAERDGRRTAELGVGAGIVIDSRAADEYAECQLKARFVTALDPGFQLIETMRAGPAGSGG
CCCCCCCCHHHHCCCCEEEEECCCCCHHHHHEEEEEEEECCCCHHHHHHHHHCCCCCCCC
APGIPLLARHLARLAASAAALGFRYDDAQVRAALARHLATLADGMHRVRLLLHKDGRIDV
CCCHHHHHHHHHHHHHHHHHHCEECCHHHHHHHHHHHHHHHHHHHHHHHHEEECCCEEEE
SGGPLPALPPGPVRVLLADAPIDGRDYLLRHKTTRRASYDAAIRAAEAAGAFDTLFFNHA
CCCCCCCCCCCCEEEEEECCCCCCCHHHHHCCHHHHHHHHHHHHHHHHCCCHHHHHHHCC
GALTEGGRSNVFVRMDGQWLTPPVEAGVLPGVMRAALLDDPAWQAHEAALTRADLARAEA
CCCCCCCCCCEEEEECCEECCCCHHCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHH
VVLCNALRGVLHVRFDQRG
HHHHHHHHHHEEEEECCCC
>Mature Secondary Structure
MESFALLDDSQAAVETPASRLYTGFCGEIRCTDPDRLEADWVRVETELAAGRHAVIVADY
CCCCEECCCCCHHHHCCHHHHHHCCCCCEECCCCCCCCCHHEEEEHHHCCCCEEEEEEEC
EWGVRLAGVTTAKPGGMLRVLLYATLQRLDGAGVAHWLAQQEGRDEPDAAGVAEWQASLE
CCCEEEEEEEECCCCCHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCCHHHHHHHHC
RPAFDAAIEAIHAAIRAGETYQINFSYRLGGRAYGSPLALYRRLRAAQPVPFGALIRLPA
CCHHHHHHHHHHHHHHCCCEEEEEEEEEECCCCCCCHHHHHHHHHHCCCCCCCEEEEECC
PTGDGDGDGGYLLSCSPELFLRHRDGVLEARPMKGTAARRGDPAADAQAAGDLAADPKNR
CCCCCCCCCCEEEEECHHHHHEECCCCCCCCCCCCCCCCCCCCCCCHHHCCCCCCCCCHH
AENLMIVDLLRNDLGRIAETGSVQVPALFAVEPYATVLQMTSTVSARLAARHAFPAVLRA
HCCEEEHHHHHHHHHHHHCCCCEECCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LFPCGSITGAPKHRSMRLIDTLEDRPRGTYTGAVGWMDAPRAGHRCGDFCLSVAIRTLAV
HHCCCCCCCCCCCCCCHHHHHHCCCCCCCEECCCCCCCCCCCCCHHHHHHHHHHHHHHHC
GAERDGRRTAELGVGAGIVIDSRAADEYAECQLKARFVTALDPGFQLIETMRAGPAGSGG
CCCCCCCCHHHHCCCCEEEEECCCCCHHHHHEEEEEEEECCCCHHHHHHHHHCCCCCCCC
APGIPLLARHLARLAASAAALGFRYDDAQVRAALARHLATLADGMHRVRLLLHKDGRIDV
CCCHHHHHHHHHHHHHHHHHHCEECCHHHHHHHHHHHHHHHHHHHHHHHHEEECCCEEEE
SGGPLPALPPGPVRVLLADAPIDGRDYLLRHKTTRRASYDAAIRAAEAAGAFDTLFFNHA
CCCCCCCCCCCCEEEEEECCCCCCCHHHHHCCHHHHHHHHHHHHHHHHCCCHHHHHHHCC
GALTEGGRSNVFVRMDGQWLTPPVEAGVLPGVMRAALLDDPAWQAHEAALTRADLARAEA
CCCCCCCCCCEEEEECCEECCCCHHCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHH
VVLCNALRGVLHVRFDQRG
HHHHHHHHHHEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3057324; 2251281 [H]