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The map label for this gene is dacC [H]

Identifier: 119896472

GI number: 119896472

Start: 196966

End: 198096

Strand: Direct

Name: dacC [H]

Synonym: azo0180

Alternate gene names: 119896472

Gene position: 196966-198096 (Clockwise)

Preceding gene: 119896471

Following gene: 119896473

Centisome position: 4.5

GC content: 65.16

Gene sequence:

>1131_bases
ATGCGTTTCGTCTTCGCCTTACTGCTGTCGCTCTTTTCGCTGCTTGCCGCCGCCCAGTCGATTCCCGCTCCCGCCCTCGC
GGCGAAGGCGTGGGTGCTGGTGGACCACAACACCGGGCAGGTGCTGGCCGCCAACGATCCCGATGCGCGGATCGAACCCG
CTTCGCTGACCAAGTTGATGACCGCCTACCTCACCTTCTCGGCGCTGAAGGCCGGCACCATCGCGCTCGACCAGCCGGTT
CCGGTGTCCGAGCGCGCCTGGCGGCAGGAAGGTTCGCGGATGTTCATCGAGCCGCAGAAGCCGGTGACAGTGCAGGAACT
CATCCGCGGCGTGATCGTGCAGTCCGGCAACGACGCCTGCGTCGCGCTTGCCGAGCTGATCGCCGGCACCGAGGAAGCCT
TCGCCGCGATGATGAATCGCGAAGCCCAGCGCCTCGGCATGAGCAATACCCACTTCACCAACTCCACCGGCCTGCCTGAC
CCGCAGCTGTACACCACGGCGAAGGACCTTGCGCTGCTCGCGTCGGCGATCATCCGCGACTTTCCGGACTACTACGCCAG
CCTCTACTCGCTGAAGGAATACCGCTACAACAACATCACCCAGCCCAACCGCAACCGCCTGCTGTGGATGGACAGCACGG
TCGACGGCATGAAGACCGGCCACACCAGCAGTGCCGGCTACTGCCTGATCTCCTCGGCGCTGCGGGGTCCGCGCCGGCTG
GTTTCGGTGGTGCTGGGGGCGGAGTCCGATACCGTGCGCGCGCAGGAGTCGCTCAAGCTGCTCAACTTCGGCTTCCAGTT
CTTCGACACCGTGAAGCTCTACTCGGCTGATCAGGCGCTGTCGCAGTTCCGCGTCTGGAAGGGGCAGGCCAATGAAGTGG
CCGCCGGTTTTACCAGCGACTTCGTGATTTCGCTGCCGAAGGGCCAGGCCGACAAGATCACGGCGACGCTGGAAAGTCGG
CAGCCGGTGCTGGCACCGCTGCAGAAGGGCCAGGAGATCGGCACGCTCAAGCTCAGCCTCGACGGCAAGCCGCTCGGCGA
ATATCCTGTGGTGGCGTTGCAGGACGTGCCGGTGGCGGGCTTCTTCGGCCGCCTGTGGGACGCCCTGGTGCTGTGGATCA
AGAGCCTGTAA

Upstream 100 bases:

>100_bases
CAAACCCTGTCCCCGCCGGTCTGTGCCCTGGGCTGCGTCCTATAATTCCGCTCCCCGCGCGTCATCCCCGTCCTTCCCCA
TTCATCCCAGGTTTTTCTCC

Downstream 100 bases:

>100_bases
GACGGCGCACCCGCGCCGGCGGGACTGAAGGACGCACGCATGAATCTGTGCTACCTGGATGGGCGCTACCTGCCGCTCGA
TGAAGCGCGGGTGTCGCCGA

Product: D-alanyl-D-alanine carboxypeptidase

Products: NA

Alternate protein names: DD-carboxypeptidase; DD-peptidase; Penicillin-binding protein 6; PBP-6 [H]

Number of amino acids: Translated: 376; Mature: 376

Protein sequence:

>376_residues
MRFVFALLLSLFSLLAAAQSIPAPALAAKAWVLVDHNTGQVLAANDPDARIEPASLTKLMTAYLTFSALKAGTIALDQPV
PVSERAWRQEGSRMFIEPQKPVTVQELIRGVIVQSGNDACVALAELIAGTEEAFAAMMNREAQRLGMSNTHFTNSTGLPD
PQLYTTAKDLALLASAIIRDFPDYYASLYSLKEYRYNNITQPNRNRLLWMDSTVDGMKTGHTSSAGYCLISSALRGPRRL
VSVVLGAESDTVRAQESLKLLNFGFQFFDTVKLYSADQALSQFRVWKGQANEVAAGFTSDFVISLPKGQADKITATLESR
QPVLAPLQKGQEIGTLKLSLDGKPLGEYPVVALQDVPVAGFFGRLWDALVLWIKSL

Sequences:

>Translated_376_residues
MRFVFALLLSLFSLLAAAQSIPAPALAAKAWVLVDHNTGQVLAANDPDARIEPASLTKLMTAYLTFSALKAGTIALDQPV
PVSERAWRQEGSRMFIEPQKPVTVQELIRGVIVQSGNDACVALAELIAGTEEAFAAMMNREAQRLGMSNTHFTNSTGLPD
PQLYTTAKDLALLASAIIRDFPDYYASLYSLKEYRYNNITQPNRNRLLWMDSTVDGMKTGHTSSAGYCLISSALRGPRRL
VSVVLGAESDTVRAQESLKLLNFGFQFFDTVKLYSADQALSQFRVWKGQANEVAAGFTSDFVISLPKGQADKITATLESR
QPVLAPLQKGQEIGTLKLSLDGKPLGEYPVVALQDVPVAGFFGRLWDALVLWIKSL
>Mature_376_residues
MRFVFALLLSLFSLLAAAQSIPAPALAAKAWVLVDHNTGQVLAANDPDARIEPASLTKLMTAYLTFSALKAGTIALDQPV
PVSERAWRQEGSRMFIEPQKPVTVQELIRGVIVQSGNDACVALAELIAGTEEAFAAMMNREAQRLGMSNTHFTNSTGLPD
PQLYTTAKDLALLASAIIRDFPDYYASLYSLKEYRYNNITQPNRNRLLWMDSTVDGMKTGHTSSAGYCLISSALRGPRRL
VSVVLGAESDTVRAQESLKLLNFGFQFFDTVKLYSADQALSQFRVWKGQANEVAAGFTSDFVISLPKGQADKITATLESR
QPVLAPLQKGQEIGTLKLSLDGKPLGEYPVVALQDVPVAGFFGRLWDALVLWIKSL

Specific function: Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors [H]

COG id: COG1686

COG function: function code M; D-alanyl-D-alanine carboxypeptidase

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein. Note=N-terminal lies in the periplasmic space [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S11 family [H]

Homologues:

Organism=Escherichia coli, GI1787062, Length=365, Percent_Identity=44.9315068493151, Blast_Score=327, Evalue=6e-91,
Organism=Escherichia coli, GI1786851, Length=360, Percent_Identity=41.6666666666667, Blast_Score=291, Evalue=5e-80,
Organism=Escherichia coli, GI87082022, Length=382, Percent_Identity=41.0994764397906, Blast_Score=268, Evalue=4e-73,
Organism=Escherichia coli, GI87082054, Length=234, Percent_Identity=29.4871794871795, Blast_Score=80, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR015956
- InterPro:   IPR018044
- InterPro:   IPR012907
- InterPro:   IPR001967 [H]

Pfam domain/function: PF07943 PBP5_C; PF00768 Peptidase_S11 [H]

EC number: =3.4.16.4 [H]

Molecular weight: Translated: 41049; Mature: 41049

Theoretical pI: Translated: 7.50; Mature: 7.50

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRFVFALLLSLFSLLAAAQSIPAPALAAKAWVLVDHNTGQVLAANDPDARIEPASLTKLM
CHHHHHHHHHHHHHHHHHHCCCCCHHHCEEEEEEECCCCCEEECCCCCCCCCHHHHHHHH
TAYLTFSALKAGTIALDQPVPVSERAWRQEGSRMFIEPQKPVTVQELIRGVIVQSGNDAC
HHHHHHHHHCCCCEEECCCCCCCHHHHHHCCCEEEECCCCCCCHHHHHHHHHCCCCCHHH
VALAELIAGTEEAFAAMMNREAQRLGMSNTHFTNSTGLPDPQLYTTAKDLALLASAIIRD
HHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
FPDYYASLYSLKEYRYNNITQPNRNRLLWMDSTVDGMKTGHTSSAGYCLISSALRGPRRL
HHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCCCHHCCCCCCCCHHHHHHHHCCHHHH
VSVVLGAESDTVRAQESLKLLNFGFQFFDTVKLYSADQALSQFRVWKGQANEVAAGFTSD
HHHHHCCCCCHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
FVISLPKGQADKITATLESRQPVLAPLQKGQEIGTLKLSLDGKPLGEYPVVALQDVPVAG
EEEECCCCCCCCEEEECCCCCCHHHHHHCCCCEEEEEEEECCCCCCCCCEEEEECCCCHH
FFGRLWDALVLWIKSL
HHHHHHHHHHHHHHCC
>Mature Secondary Structure
MRFVFALLLSLFSLLAAAQSIPAPALAAKAWVLVDHNTGQVLAANDPDARIEPASLTKLM
CHHHHHHHHHHHHHHHHHHCCCCCHHHCEEEEEEECCCCCEEECCCCCCCCCHHHHHHHH
TAYLTFSALKAGTIALDQPVPVSERAWRQEGSRMFIEPQKPVTVQELIRGVIVQSGNDAC
HHHHHHHHHCCCCEEECCCCCCCHHHHHHCCCEEEECCCCCCCHHHHHHHHHCCCCCHHH
VALAELIAGTEEAFAAMMNREAQRLGMSNTHFTNSTGLPDPQLYTTAKDLALLASAIIRD
HHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
FPDYYASLYSLKEYRYNNITQPNRNRLLWMDSTVDGMKTGHTSSAGYCLISSALRGPRRL
HHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCCCHHCCCCCCCCHHHHHHHHCCHHHH
VSVVLGAESDTVRAQESLKLLNFGFQFFDTVKLYSADQALSQFRVWKGQANEVAAGFTSD
HHHHHCCCCCHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
FVISLPKGQADKITATLESRQPVLAPLQKGQEIGTLKLSLDGKPLGEYPVVALQDVPVAG
EEEECCCCCCCCEEEECCCCCCHHHHHHCCCCEEEEEEEECCCCCCCCCEEEEECCCCHH
FFGRLWDALVLWIKSL
HHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 3279397; 8905232; 9278503; 7042389 [H]