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The map label for this gene is ilvE1 [H]

Identifier: 119896425

GI number: 119896425

Start: 148401

End: 149321

Strand: Direct

Name: ilvE1 [H]

Synonym: azo0133

Alternate gene names: 119896425

Gene position: 148401-149321 (Clockwise)

Preceding gene: 119896424

Following gene: 119896430

Centisome position: 3.39

GC content: 70.36

Gene sequence:

>921_bases
ATGAGCATGGAAGACCGCGACGGCTGGATCTGGATGGACGGGCAATGGCTACCCTGGCGCGATGCCAAAGTGCACGCGCT
GACCCACACGCTGCACTACGGGCTGGGCTGTTTCGAAGGCATCCGCGCCTACCCCACCGCCCACGGCCCGGCCGTGTTCC
GGCTGGACGATCACATCGAGCGCCTGTTCGATTCGGCGCACATCCTCGGGCTGGCCATGCCTTGCACGCCGGCGGAAGTC
CGCGCGGCCTGTCTCGAGGCGGTGCGGCGCAACGGGCTGGACGGCGGCTATATCCGCCCGCTGGTGTTTCTGGGCGCGGA
AAAAGTGGGCGTCGACCCCGCCGGGGCGGCCACCCATGTGATGGTGGCGGCGTGGCAGTGGGGCGCCTACCTCGGCGCGC
AAGCGCTCGAGCGCGGTATCCGCGTCAAGGTCGCGAGCTTCGCCCGCCATCATGTGAACGTGCAGATGTGCCGCGCCAAG
TCGGTGTCGACCTACACCAACTCCATCCTCGCCTGCCGCGAGGCGCGCGCCGAAGGCTATGACGAGGCGCTGCTGCTCGA
CACCGACGGCTTCGTTGCCGAGGGGCCGGGCGAGAACGTGTTCGTGGTCAAGCGCGGCGTGATCTACGAGCCGGAGATCA
CCTCCGCGCTGGACGGCATCACCCGGCGCACGCTGCAGACCCTGGCCAGCGAGGCCGGCTACGAGATCCGCGCCCGCCGC
ATCACCCGCGACGAGCTGTACATCGCCGACGAGGTGTTCTTCACCGGCACCGCGGCGGAGATCACCCCGGTGGTGGAGGT
GGATAGGCGCCGCGTCGGCAGCGGCAGGCCGGGGCCGGTGACGCAGGCGCTGCAGCGCCGCTTCTTCGCCTGCGTGCGCG
GTGAGGACCCGGCCCACGCCGACTGGCTGGCCCCCGCCTAG

Upstream 100 bases:

>100_bases
CCCCCGCTTCTTCCGCGCCGACGGCCCATGCCGGCGACCGCCGGTGTGCCCCGGTTCCGCGCCCCGCGGAGCCGTTTCCC
ACGCAAACCTGGAGCACATC

Downstream 100 bases:

>100_bases
GCGTCGCCGGACGAGGCGGGCGCCGCGGCCACCGCCTCGCCGCCCAGCACGTAGCGGTTGCGGCCTTCGTGCTTGGCCTG
GTACAGCAGCGCGTCCGCTT

Product: branched-chain-amino-acid transaminase

Products: NA

Alternate protein names: BCAT [H]

Number of amino acids: Translated: 306; Mature: 305

Protein sequence:

>306_residues
MSMEDRDGWIWMDGQWLPWRDAKVHALTHTLHYGLGCFEGIRAYPTAHGPAVFRLDDHIERLFDSAHILGLAMPCTPAEV
RAACLEAVRRNGLDGGYIRPLVFLGAEKVGVDPAGAATHVMVAAWQWGAYLGAQALERGIRVKVASFARHHVNVQMCRAK
SVSTYTNSILACREARAEGYDEALLLDTDGFVAEGPGENVFVVKRGVIYEPEITSALDGITRRTLQTLASEAGYEIRARR
ITRDELYIADEVFFTGTAAEITPVVEVDRRRVGSGRPGPVTQALQRRFFACVRGEDPAHADWLAPA

Sequences:

>Translated_306_residues
MSMEDRDGWIWMDGQWLPWRDAKVHALTHTLHYGLGCFEGIRAYPTAHGPAVFRLDDHIERLFDSAHILGLAMPCTPAEV
RAACLEAVRRNGLDGGYIRPLVFLGAEKVGVDPAGAATHVMVAAWQWGAYLGAQALERGIRVKVASFARHHVNVQMCRAK
SVSTYTNSILACREARAEGYDEALLLDTDGFVAEGPGENVFVVKRGVIYEPEITSALDGITRRTLQTLASEAGYEIRARR
ITRDELYIADEVFFTGTAAEITPVVEVDRRRVGSGRPGPVTQALQRRFFACVRGEDPAHADWLAPA
>Mature_305_residues
SMEDRDGWIWMDGQWLPWRDAKVHALTHTLHYGLGCFEGIRAYPTAHGPAVFRLDDHIERLFDSAHILGLAMPCTPAEVR
AACLEAVRRNGLDGGYIRPLVFLGAEKVGVDPAGAATHVMVAAWQWGAYLGAQALERGIRVKVASFARHHVNVQMCRAKS
VSTYTNSILACREARAEGYDEALLLDTDGFVAEGPGENVFVVKRGVIYEPEITSALDGITRRTLQTLASEAGYEIRARRI
TRDELYIADEVFFTGTAAEITPVVEVDRRRVGSGRPGPVTQALQRRFFACVRGEDPAHADWLAPA

Specific function: Acts on leucine, isoleucine and valine [H]

COG id: COG0115

COG function: function code EH; Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Escherichia coli, GI48994963, Length=297, Percent_Identity=48.1481481481481, Blast_Score=279, Evalue=1e-76,
Organism=Caenorhabditis elegans, GI17565728, Length=288, Percent_Identity=26.0416666666667, Blast_Score=67, Evalue=1e-11,

Paralogues:

None

Copy number: 2342 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 11,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001544
- InterPro:   IPR018300
- InterPro:   IPR005785 [H]

Pfam domain/function: PF01063 Aminotran_4 [H]

EC number: =2.6.1.42 [H]

Molecular weight: Translated: 33745; Mature: 33614

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSMEDRDGWIWMDGQWLPWRDAKVHALTHTLHYGLGCFEGIRAYPTAHGPAVFRLDDHIE
CCCCCCCCEEEECCEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEHHHHH
RLFDSAHILGLAMPCTPAEVRAACLEAVRRNGLDGGYIRPLVFLGAEKVGVDPAGAATHV
HHHCCHHHEEEECCCCHHHHHHHHHHHHHHCCCCCCHHHHHHEECCHHCCCCCCCCHHEE
MVAAWQWGAYLGAQALERGIRVKVASFARHHVNVQMCRAKSVSTYTNSILACREARAEGY
EEEEEHHHHHHHHHHHHCCCEEEEHHHHHHHCCEEEECCCCHHHHHHHHHHHHHHHHCCC
DEALLLDTDGFVAEGPGENVFVVKRGVIYEPEITSALDGITRRTLQTLASEAGYEIRARR
CCEEEEECCCCEECCCCCCEEEEECCEEECCCHHHHHHHHHHHHHHHHHHHCCCEEEEEE
ITRDELYIADEVFFTGTAAEITPVVEVDRRRVGSGRPGPVTQALQRRFFACVRGEDPAHA
ECCCCEEEEEEEEEECCHHHCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCCC
DWLAPA
CCCCCC
>Mature Secondary Structure 
SMEDRDGWIWMDGQWLPWRDAKVHALTHTLHYGLGCFEGIRAYPTAHGPAVFRLDDHIE
CCCCCCCEEEECCEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEHHHHH
RLFDSAHILGLAMPCTPAEVRAACLEAVRRNGLDGGYIRPLVFLGAEKVGVDPAGAATHV
HHHCCHHHEEEECCCCHHHHHHHHHHHHHHCCCCCCHHHHHHEECCHHCCCCCCCCHHEE
MVAAWQWGAYLGAQALERGIRVKVASFARHHVNVQMCRAKSVSTYTNSILACREARAEGY
EEEEEHHHHHHHHHHHHCCCEEEEHHHHHHHCCEEEECCCCHHHHHHHHHHHHHHHHCCC
DEALLLDTDGFVAEGPGENVFVVKRGVIYEPEITSALDGITRRTLQTLASEAGYEIRARR
CCEEEEECCCCEECCCCCCEEEEECCEEECCCHHHHHHHHHHHHHHHHHHHCCCEEEEEE
ITRDELYIADEVFFTGTAAEITPVVEVDRRRVGSGRPGPVTQALQRRFFACVRGEDPAHA
ECCCCEEEEEEEEEECCHHHCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCCC
DWLAPA
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]