BacMap

Definition	Azoarcus sp. BH72 chromosome, complete genome.
Accession	NC_008702
Length	4,376,040

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The map label for this gene is livF [H]

Identifier: 119896410

GI number: 119896410

Start: 135870

End: 136592

Strand: Direct

Name: livF [H]

Synonym: azo0118

Alternate gene names: 119896410

Gene position: 135870-136592 (Clockwise)

Preceding gene: 119896409

Following gene: 119896411

Centisome position: 3.1

GC content: 65.84

Gene sequence:

>723_bases
ATGACCAGCGCCTTTGAATCCCATGCCGAAATGCTGCGGATCAGCGATCTGCACGCCTTCTACGGCGAATCCCACATCCT
GCACGGCATCGACCTGCAGGTCGCGCGCGGCGAATGCGTCACCTTGCTCGGGCGTAACGGCTCCGGCCGCTCGACCACGC
TGAAGTCCATCCTCGGCCTGGTCGGCCGCCGCAGCGGCTCGATCATGGTGAATGGCAACGAGGTCATCGCCGAGCCCACC
CACCGCATGGCGCGCCACGGCGTCGGCTACGTGCCGGAGGAACGCGCGATCTTCGCCTCGCTGACGGCCGAGGAGAACCT
GCTGCTGCCGCCGCAGGTATCCAGCGGCGGCATGAGCGTGGACGAGATCTACGGGATGTTCCCCAACCTGCTCGAACGCC
GCAACAGCCCGGGTACCAAGCTGTCCGGCGGCGAACAGCAGATGCTGGCGATGGCGCGCGTGCTGCGTACCGGGGCCAAG
CTGCTGCTGCTCGACGAGATCACCGAAGGCCTCGCGCCGGTCATCGTCAAGAAGCTCGGCGAGGTCATCACCGAACTGAA
ATCGCGCGGTTTCACCATCGTGCTGGTGGAGCAGAACTTCCGCTTTGCCGCGCCGCTGGCCGACCGCCACTACGTGCTCG
AGCACGGCGAGATCATCGCCACCATCCAGAAGGACGAACTGCCAGGACGGATGGACTGGCTGCACCAGACGCTCGGGGTC
TGA

Upstream 100 bases:

>100_bases
GGCAGCTACGAAGAAGTGTCGAAGAATCCCAAGGTGCTCGAAGCCTACGTCGGTTCCGACGACATGGCCGACGCCCATCA
CTAGGCCGAGGCCACGATCC

Downstream 100 bases:

>100_bases
CCCGGTGCGCCACCACAACGAACGGAGACGAGACATGCATACGAAGAAGCTGTTGACCGCCGCCTGCACCGCGGCCCTGG
CGATGCTGGCCACCGGCGCG

Product: ABC transporter ATP-binding protein

Products: ADP; phosphate; L-leucine [Cytoplasm]; ADP; L-valine [Cytoplasm]; L-iso-leucine [Cytoplasm] [C]

Alternate protein names: LIV-I protein F [H]

Number of amino acids: Translated: 240; Mature: 239

Protein sequence:

>240_residues
MTSAFESHAEMLRISDLHAFYGESHILHGIDLQVARGECVTLLGRNGSGRSTTLKSILGLVGRRSGSIMVNGNEVIAEPT
HRMARHGVGYVPEERAIFASLTAEENLLLPPQVSSGGMSVDEIYGMFPNLLERRNSPGTKLSGGEQQMLAMARVLRTGAK
LLLLDEITEGLAPVIVKKLGEVITELKSRGFTIVLVEQNFRFAAPLADRHYVLEHGEIIATIQKDELPGRMDWLHQTLGV

Sequences:

>Translated_240_residues
MTSAFESHAEMLRISDLHAFYGESHILHGIDLQVARGECVTLLGRNGSGRSTTLKSILGLVGRRSGSIMVNGNEVIAEPT
HRMARHGVGYVPEERAIFASLTAEENLLLPPQVSSGGMSVDEIYGMFPNLLERRNSPGTKLSGGEQQMLAMARVLRTGAK
LLLLDEITEGLAPVIVKKLGEVITELKSRGFTIVLVEQNFRFAAPLADRHYVLEHGEIIATIQKDELPGRMDWLHQTLGV
>Mature_239_residues
TSAFESHAEMLRISDLHAFYGESHILHGIDLQVARGECVTLLGRNGSGRSTTLKSILGLVGRRSGSIMVNGNEVIAEPTH
RMARHGVGYVPEERAIFASLTAEENLLLPPQVSSGGMSVDEIYGMFPNLLERRNSPGTKLSGGEQQMLAMARVLRTGAKL
LLLDEITEGLAPVIVKKLGEVITELKSRGFTIVLVEQNFRFAAPLADRHYVLEHGEIIATIQKDELPGRMDWLHQTLGV

Specific function: Component of the leucine-specific transport system [H]

COG id: COG0410

COG function: function code E; ABC-type branched-chain amino acid transport systems, ATPase component

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Homo sapiens, GI45446740, Length=198, Percent_Identity=29.2929292929293, Blast_Score=80, Evalue=1e-15,
Organism=Homo sapiens, GI47078218, Length=198, Percent_Identity=29.2929292929293, Blast_Score=80, Evalue=1e-15,
Organism=Homo sapiens, GI105990541, Length=198, Percent_Identity=27.7777777777778, Blast_Score=79, Evalue=4e-15,
Organism=Homo sapiens, GI31657092, Length=211, Percent_Identity=24.6445497630332, Blast_Score=78, Evalue=9e-15,
Organism=Homo sapiens, GI21536376, Length=201, Percent_Identity=26.3681592039801, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI27881501, Length=203, Percent_Identity=28.0788177339901, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI30795238, Length=203, Percent_Identity=28.0788177339901, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI116734710, Length=193, Percent_Identity=30.0518134715026, Blast_Score=75, Evalue=5e-14,
Organism=Homo sapiens, GI9961252, Length=176, Percent_Identity=31.8181818181818, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI4505771, Length=176, Percent_Identity=31.8181818181818, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI42741659, Length=174, Percent_Identity=32.7586206896552, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI255708477, Length=176, Percent_Identity=28.4090909090909, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI148612844, Length=176, Percent_Identity=28.4090909090909, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI153792144, Length=219, Percent_Identity=26.9406392694064, Blast_Score=65, Evalue=4e-11,
Organism=Homo sapiens, GI27262624, Length=217, Percent_Identity=27.6497695852535, Blast_Score=65, Evalue=4e-11,
Organism=Homo sapiens, GI27262626, Length=217, Percent_Identity=27.6497695852535, Blast_Score=65, Evalue=4e-11,
Organism=Homo sapiens, GI150417984, Length=206, Percent_Identity=26.6990291262136, Blast_Score=65, Evalue=6e-11,
Organism=Escherichia coli, GI87082268, Length=220, Percent_Identity=39.5454545454545, Blast_Score=157, Evalue=5e-40,
Organism=Escherichia coli, GI1789593, Length=215, Percent_Identity=31.6279069767442, Blast_Score=111, Evalue=5e-26,
Organism=Escherichia coli, GI1787029, Length=216, Percent_Identity=33.3333333333333, Blast_Score=108, Evalue=3e-25,
Organism=Escherichia coli, GI1789672, Length=225, Percent_Identity=32.8888888888889, Blast_Score=108, Evalue=4e-25,
Organism=Escherichia coli, GI1787089, Length=219, Percent_Identity=32.4200913242009, Blast_Score=97, Evalue=9e-22,
Organism=Escherichia coli, GI48995001, Length=231, Percent_Identity=27.2727272727273, Blast_Score=96, Evalue=2e-21,
Organism=Escherichia coli, GI1788225, Length=217, Percent_Identity=32.258064516129, Blast_Score=91, Evalue=9e-20,
Organism=Escherichia coli, GI1788450, Length=218, Percent_Identity=31.1926605504587, Blast_Score=89, Evalue=2e-19,
Organism=Escherichia coli, GI1790162, Length=240, Percent_Identity=27.0833333333333, Blast_Score=88, Evalue=4e-19,
Organism=Escherichia coli, GI1789864, Length=249, Percent_Identity=26.9076305220884, Blast_Score=88, Evalue=5e-19,
Organism=Escherichia coli, GI1789991, Length=220, Percent_Identity=27.2727272727273, Blast_Score=86, Evalue=2e-18,
Organism=Escherichia coli, GI1788897, Length=218, Percent_Identity=29.3577981651376, Blast_Score=86, Evalue=2e-18,
Organism=Escherichia coli, GI1790190, Length=218, Percent_Identity=28.4403669724771, Blast_Score=84, Evalue=8e-18,
Organism=Escherichia coli, GI1787792, Length=220, Percent_Identity=29.0909090909091, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1786319, Length=215, Percent_Identity=31.1627906976744, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI1786398, Length=222, Percent_Identity=26.5765765765766, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI1788761, Length=226, Percent_Identity=30.0884955752212, Blast_Score=82, Evalue=2e-17,
Organism=Escherichia coli, GI1788472, Length=220, Percent_Identity=28.6363636363636, Blast_Score=82, Evalue=3e-17,
Organism=Escherichia coli, GI1786253, Length=225, Percent_Identity=31.1111111111111, Blast_Score=81, Evalue=5e-17,
Organism=Escherichia coli, GI1786872, Length=222, Percent_Identity=31.5315315315315, Blast_Score=81, Evalue=6e-17,
Organism=Escherichia coli, GI1787105, Length=224, Percent_Identity=29.4642857142857, Blast_Score=77, Evalue=9e-16,
Organism=Escherichia coli, GI87081791, Length=226, Percent_Identity=27.4336283185841, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI1787112, Length=235, Percent_Identity=33.1914893617021, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI1786703, Length=212, Percent_Identity=32.0754716981132, Blast_Score=75, Evalue=6e-15,
Organism=Escherichia coli, GI1786698, Length=173, Percent_Identity=28.9017341040462, Blast_Score=74, Evalue=6e-15,
Organism=Escherichia coli, GI87081782, Length=221, Percent_Identity=29.8642533936652, Blast_Score=74, Evalue=8e-15,
Organism=Escherichia coli, GI1790525, Length=228, Percent_Identity=26.7543859649123, Blast_Score=74, Evalue=9e-15,
Organism=Escherichia coli, GI1788210, Length=203, Percent_Identity=27.5862068965517, Blast_Score=73, Evalue=1e-14,
Organism=Escherichia coli, GI1788644, Length=226, Percent_Identity=29.2035398230088, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI48994943, Length=226, Percent_Identity=24.7787610619469, Blast_Score=71, Evalue=7e-14,
Organism=Escherichia coli, GI1787370, Length=218, Percent_Identity=27.5229357798165, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1788165, Length=213, Percent_Identity=27.2300469483568, Blast_Score=69, Evalue=2e-13,
Organism=Escherichia coli, GI87081709, Length=206, Percent_Identity=28.1553398058252, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1787758, Length=202, Percent_Identity=27.2277227722772, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI87081834, Length=203, Percent_Identity=28.0788177339901, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1790467, Length=215, Percent_Identity=26.9767441860465, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI1789873, Length=209, Percent_Identity=24.8803827751196, Blast_Score=65, Evalue=4e-12,
Organism=Escherichia coli, GI1790739, Length=237, Percent_Identity=26.1603375527426, Blast_Score=65, Evalue=5e-12,
Organism=Escherichia coli, GI1790534, Length=198, Percent_Identity=29.7979797979798, Blast_Score=64, Evalue=7e-12,
Organism=Escherichia coli, GI1787712, Length=215, Percent_Identity=25.5813953488372, Blast_Score=63, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI193211017, Length=225, Percent_Identity=31.5555555555556, Blast_Score=86, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI71996809, Length=225, Percent_Identity=31.5555555555556, Blast_Score=86, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI193211015, Length=225, Percent_Identity=31.5555555555556, Blast_Score=85, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI17510237, Length=210, Percent_Identity=30, Blast_Score=83, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI71983523, Length=230, Percent_Identity=27.3913043478261, Blast_Score=81, Evalue=5e-16,
Organism=Caenorhabditis elegans, GI71983516, Length=230, Percent_Identity=27.3913043478261, Blast_Score=81, Evalue=5e-16,
Organism=Caenorhabditis elegans, GI71983510, Length=230, Percent_Identity=27.3913043478261, Blast_Score=81, Evalue=5e-16,
Organism=Caenorhabditis elegans, GI17565586, Length=199, Percent_Identity=27.6381909547739, Blast_Score=77, Evalue=8e-15,
Organism=Caenorhabditis elegans, GI25146777, Length=155, Percent_Identity=32.9032258064516, Blast_Score=76, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI71984940, Length=216, Percent_Identity=28.7037037037037, Blast_Score=70, Evalue=9e-13,
Organism=Caenorhabditis elegans, GI115533608, Length=223, Percent_Identity=28.2511210762332, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI212646699, Length=155, Percent_Identity=30.9677419354839, Blast_Score=69, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17541710, Length=158, Percent_Identity=34.8101265822785, Blast_Score=68, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI193208177, Length=158, Percent_Identity=32.2784810126582, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI115534520, Length=166, Percent_Identity=30.7228915662651, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI193202349, Length=231, Percent_Identity=24.6753246753247, Blast_Score=65, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI25146765, Length=152, Percent_Identity=32.2368421052632, Blast_Score=65, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI86564969, Length=152, Percent_Identity=32.2368421052632, Blast_Score=65, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI71992070, Length=152, Percent_Identity=32.2368421052632, Blast_Score=65, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI71992066, Length=152, Percent_Identity=32.2368421052632, Blast_Score=65, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17569143, Length=157, Percent_Identity=29.9363057324841, Blast_Score=65, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI71996550, Length=222, Percent_Identity=25.6756756756757, Blast_Score=65, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI71992285, Length=214, Percent_Identity=26.1682242990654, Blast_Score=64, Evalue=7e-11,
Organism=Saccharomyces cerevisiae, GI6323217, Length=210, Percent_Identity=28.0952380952381, Blast_Score=65, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24648314, Length=213, Percent_Identity=24.8826291079812, Blast_Score=85, Evalue=4e-17,
Organism=Drosophila melanogaster, GI24666092, Length=211, Percent_Identity=26.5402843601896, Blast_Score=84, Evalue=1e-16,
Organism=Drosophila melanogaster, GI221512771, Length=213, Percent_Identity=27.6995305164319, Blast_Score=81, Evalue=5e-16,
Organism=Drosophila melanogaster, GI116007184, Length=230, Percent_Identity=27.8260869565217, Blast_Score=79, Evalue=4e-15,
Organism=Drosophila melanogaster, GI221500365, Length=230, Percent_Identity=27.8260869565217, Blast_Score=79, Evalue=4e-15,
Organism=Drosophila melanogaster, GI24643674, Length=223, Percent_Identity=24.6636771300448, Blast_Score=75, Evalue=5e-14,
Organism=Drosophila melanogaster, GI28574150, Length=218, Percent_Identity=26.1467889908257, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI116007328, Length=218, Percent_Identity=26.1467889908257, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI85725262, Length=223, Percent_Identity=29.1479820627803, Blast_Score=73, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24650853, Length=201, Percent_Identity=27.8606965174129, Blast_Score=68, Evalue=6e-12,
Organism=Drosophila melanogaster, GI17136662, Length=218, Percent_Identity=27.0642201834862, Blast_Score=68, Evalue=6e-12,
Organism=Drosophila melanogaster, GI24650855, Length=201, Percent_Identity=27.8606965174129, Blast_Score=68, Evalue=7e-12,
Organism=Drosophila melanogaster, GI24582014, Length=218, Percent_Identity=26.605504587156, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24582012, Length=218, Percent_Identity=26.605504587156, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI281362751, Length=201, Percent_Identity=27.8606965174129, Blast_Score=66, Evalue=2e-11,
Organism=Drosophila melanogaster, GI19920532, Length=204, Percent_Identity=28.921568627451, Blast_Score=65, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24580930, Length=204, Percent_Identity=28.921568627451, Blast_Score=65, Evalue=3e-11,
Organism=Drosophila melanogaster, GI28573573, Length=219, Percent_Identity=26.027397260274, Blast_Score=64, Evalue=7e-11,
Organism=Drosophila melanogaster, GI28573571, Length=219, Percent_Identity=26.027397260274, Blast_Score=64, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR003593 [H]

Pfam domain/function: PF00005 ABC_tran [H]

EC number: NA

Molecular weight: Translated: 26278; Mature: 26147

Theoretical pI: Translated: 6.61; Mature: 6.61

Prosite motif: PS00211 ABC_TRANSPORTER_1 ; PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSAFESHAEMLRISDLHAFYGESHILHGIDLQVARGECVTLLGRNGSGRSTTLKSILGL
CCCCHHHHHHHHHHHHHHHHHCCCCEEECCEEEEECCCEEEEEECCCCCCHHHHHHHHHH
VGRRSGSIMVNGNEVIAEPTHRMARHGVGYVPEERAIFASLTAEENLLLPPQVSSGGMSV
HCCCCCCEEECCCEEEECHHHHHHHCCCCCCCCCCEEEEEECCCCCEECCCCCCCCCCCH
DEIYGMFPNLLERRNSPGTKLSGGEQQMLAMARVLRTGAKLLLLDEITEGLAPVIVKKLG
HHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHH
EVITELKSRGFTIVLVEQNFRFAAPLADRHYVLEHGEIIATIQKDELPGRMDWLHQTLGV
HHHHHHHHCCCEEEEEECCCEEECCCCCCCEEEECCCEEEEEECCCCCCHHHHHHHHHCC
>Mature Secondary Structure 
TSAFESHAEMLRISDLHAFYGESHILHGIDLQVARGECVTLLGRNGSGRSTTLKSILGL
CCCHHHHHHHHHHHHHHHHHCCCCEEECCEEEEECCCEEEEEECCCCCCHHHHHHHHHH
VGRRSGSIMVNGNEVIAEPTHRMARHGVGYVPEERAIFASLTAEENLLLPPQVSSGGMSV
HCCCCCCEEECCCEEEECHHHHHHHCCCCCCCCCCEEEEEECCCCCEECCCCCCCCCCCH
DEIYGMFPNLLERRNSPGTKLSGGEQQMLAMARVLRTGAKLLLLDEITEGLAPVIVKKLG
HHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHH
EVITELKSRGFTIVLVEQNFRFAAPLADRHYVLEHGEIIATIQKDELPGRMDWLHQTLGV
HHHHHHHHCCCEEEEEECCCEEECCCCCCCEEEECCCEEEEEECCCCCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; L-leucine [Periplasm]; H2O; ATP; L-valine [Periplasm]; L-iso-leucine [Periplasm] [C]

Specific reaction: ATP + L-leucine [Periplasm] + H2O = ADP + phosphate + L-leucine [Cytoplasm] ATP + L-valine [Periplasm] + H2O = ADP + phosphate + L-valine [Cytoplasm] ATP + L-iso-leucine [Periplasm] + H2O = ADP + phosphate + L-iso-leucine [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2195019; 8041620; 9278503 [H]