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The map label for this gene is yihZ

Identifier: 119896401

GI number: 119896401

Start: 127357

End: 127812

Strand: Direct

Name: yihZ

Synonym: azo0109

Alternate gene names: 119896401

Gene position: 127357-127812 (Clockwise)

Preceding gene: 119896400

Following gene: 119896403

Centisome position: 2.91

GC content: 71.27

Gene sequence:

>456_bases
ATGATGGCCTTGCTGCAGCGCGTGACGCGCGCCCGGGTGACGGTGGACGGCGCGACCACCGGCGAGATCGGTACCGGCCT
GCTGGCGCTGGTGTGCGCCGAGCAGGGCGACACCGAAGCCGAGGCCGACAAGCTGCTCGCCAAGCTCCTCAAGCTGCGCG
TCTTTGCCGACGAGGGCGGACGCATGAACCGCTCGCTGCAGGAGGTCGGCGGCGGTCTGCTGGTCGTCAGCCAGTTCACG
CTCGCGGCCGATACCAGCGGCGGCAACCGGCCGAGCTTCGCCAACGCCGCGCCCGCCGACACCGGACGGGCGCTGTACGA
GCATTTCGTCGCCCGTGCGCGCGCGCAGCATGGCGAGGTTGCCACCGGCCGCTTCGGCGCGATGATGCAGGTCGAGCTGG
TCAATGACGGTCCGGTGACGATCCCGCTGCGCATCCCGCCCGCAAGCGCGGCTTGA

Upstream 100 bases:

>100_bases
GGTCGCTACCGCCAACCTGCCCTTCCTGGTGCGCTGAAGCGCTTGCCGCCGGCCCGGTGCTGACGTAGCGTCGCCGGCTT
TGCCGAGGAGAACGCTTGCG

Downstream 100 bases:

>100_bases
CGCAAGGCCGCTTCAGGCCACGGTTTCGGGCAGCGGGATGAACTCGGCGTTGTCGTTGGGCGGCAGCGGAATGCGTCCCG
CGCGCCAGTCGGCCTTGGCC

Product: D-tyrosyl-tRNA(Tyr) deacylase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 151; Mature: 151

Protein sequence:

>151_residues
MMALLQRVTRARVTVDGATTGEIGTGLLALVCAEQGDTEAEADKLLAKLLKLRVFADEGGRMNRSLQEVGGGLLVVSQFT
LAADTSGGNRPSFANAAPADTGRALYEHFVARARAQHGEVATGRFGAMMQVELVNDGPVTIPLRIPPASAA

Sequences:

>Translated_151_residues
MMALLQRVTRARVTVDGATTGEIGTGLLALVCAEQGDTEAEADKLLAKLLKLRVFADEGGRMNRSLQEVGGGLLVVSQFT
LAADTSGGNRPSFANAAPADTGRALYEHFVARARAQHGEVATGRFGAMMQVELVNDGPVTIPLRIPPASAA
>Mature_151_residues
MMALLQRVTRARVTVDGATTGEIGTGLLALVCAEQGDTEAEADKLLAKLLKLRVFADEGGRMNRSLQEVGGGLLVVSQFT
LAADTSGGNRPSFANAAPADTGRALYEHFVARARAQHGEVATGRFGAMMQVELVNDGPVTIPLRIPPASAA

Specific function: Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine

COG id: COG1490

COG function: function code J; D-Tyr-tRNAtyr deacylase

Gene ontology:

Cell location: Cytoplasm (Probable)

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DTD family

Homologues:

Organism=Homo sapiens, GI30795227, Length=149, Percent_Identity=40.9395973154362, Blast_Score=108, Evalue=1e-24,
Organism=Escherichia coli, GI1790320, Length=145, Percent_Identity=55.8620689655172, Blast_Score=164, Evalue=2e-42,
Organism=Caenorhabditis elegans, GI115533292, Length=146, Percent_Identity=38.3561643835616, Blast_Score=94, Evalue=2e-20,
Organism=Saccharomyces cerevisiae, GI6319982, Length=146, Percent_Identity=42.4657534246575, Blast_Score=113, Evalue=1e-26,
Organism=Drosophila melanogaster, GI281361569, Length=148, Percent_Identity=40.5405405405405, Blast_Score=107, Evalue=3e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DTD_AZOSB (A1K1M2)

Other databases:

- EMBL:   AM406670
- RefSeq:   YP_931614.1
- ProteinModelPortal:   A1K1M2
- SMR:   A1K1M2
- STRING:   A1K1M2
- GeneID:   4606219
- GenomeReviews:   AM406670_GR
- KEGG:   azo:azo0109
- eggNOG:   COG1490
- HOGENOM:   HBG286048
- OMA:   MKAVIQR
- PhylomeDB:   A1K1M2
- ProtClustDB:   PRK05273
- BioCyc:   ASP62928:AZO0109-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00518
- InterPro:   IPR003732
- Gene3D:   G3DSA:3.50.80.10
- PANTHER:   PTHR10472
- TIGRFAMs:   TIGR00256

Pfam domain/function: PF02580 Tyr_Deacylase; SSF69500 DTyrtRNA_deacyls

EC number: NA

Molecular weight: Translated: 15760; Mature: 15760

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: NA

Important sites: ACT_SITE 80-80

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMALLQRVTRARVTVDGATTGEIGTGLLALVCAEQGDTEAEADKLLAKLLKLRVFADEGG
CHHHHHHHHHHEEEECCCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCC
RMNRSLQEVGGGLLVVSQFTLAADTSGGNRPSFANAAPADTGRALYEHFVARARAQHGEV
CCCHHHHHHCCCEEEEEEEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCC
ATGRFGAMMQVELVNDGPVTIPLRIPPASAA
CCCCCCCEEEEEEECCCCEEEEEECCCCCCC
>Mature Secondary Structure
MMALLQRVTRARVTVDGATTGEIGTGLLALVCAEQGDTEAEADKLLAKLLKLRVFADEGG
CHHHHHHHHHHEEEECCCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCC
RMNRSLQEVGGGLLVVSQFTLAADTSGGNRPSFANAAPADTGRALYEHFVARARAQHGEV
CCCHHHHHHCCCEEEEEEEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCC
ATGRFGAMMQVELVNDGPVTIPLRIPPASAA
CCCCCCCEEEEEEECCCCEEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA