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The map label for this gene is yfcX [C]

Identifier: 119896358

GI number: 119896358

Start: 77284

End: 78402

Strand: Reverse

Name: yfcX [C]

Synonym: azo0066

Alternate gene names: 119896358

Gene position: 78402-77284 (Counterclockwise)

Preceding gene: 119896360

Following gene: 119896357

Centisome position: 1.79

GC content: 73.19

Gene sequence:

>1119_bases
ATGACCGCCGCCGTCCTGCTGCGCGAGATTCCCACTGCCTGCGGCCGCCGCTTCGGCCATGCCACGCTCAATGCCGAGCG
CGCGTTGAACGCGCTGTCGCTGGAGATGATCGACCTGCTTGCGCCGCAGCTGGACGCCTGGGCGGCCGATCCCGACATCG
TCGGCGTGGTGCTCGACGGCAGCGGCGACAAGGCCTTCTGCGCCGGCGGTGACGTCGCCGCCTTGTACCGCGCGCTGCGT
GCTCACGATGGTGATGCGCCGCCGCAGGCGGTCACCGACTTCTTCGAGCGCGAATACCGCCTCGATTACCGCATCCACAC
CTATCCCAAGCCGCTGCTGTGCTGGGGCCACGGCATCGTGATGGGCGGCGGCATCGGCCTGCTCGCCGGGGCCTCGCACC
GGGTGGCGACGCTGCAGACGCGGATGGCGATGCCGGAGATCACGATCGGCCTGTATCCGGATGTCGGCGGCTCGTGGTTC
CTGCCGCGCATGCCCGGGCGCGCGGGTCTGTTCCTCGCGCTCACCGGCGCGCCGCTCAACGCCGCCGACGCGCGCTTTGC
CGGGCTGGCGGATTTTGTCCTCGACCACGGCGCCCGCGGCGGCGTGCTGGCCGCGCTCGGTGCCACCCGCTGGGCGGGCG
ACGCCGCCGCCGACCGCCTGCGGCTGGACCATCTGCTGGGCGAATTCAGCGTGCGCGAGGGCATGCCGGCCGCGCCGCTG
CGCACCCACCTCGACCGCATCGAGGCCGTCGTGGGGCGCGGCAGCCTGGCCGAGATCGCGGTGCGACTGCACGCGCTCGC
CGCCGACCCCGACCCCTGGCTGGCGGCCGCGGCGGGCAGCTTCGTGCGCGGCGCGCCGAGTTCGGCGGCGCTGTCGCTCG
AACTGTGGCGGCGTGCCCGCCACCTGTCGCTGGCCGAGGTGTTCCGGCTGGAATACATCGTCTCGGTGGCCGCCACCGGG
CGCGCCGATTTCGTCGAAGGCGTGCGCGCGCTGCTGATCGACAAGGACCGCAAGCCGCGCTGGCAGCACGCCGACGTGGG
CGCGGTCGACACCGCCTTTATCGCCGACAACTTCCGCGCCCGCTTCGACGGCGCGCACCCGCTGGCGGACCTGGCATGA

Upstream 100 bases:

>100_bases
CAGGGCGCGAACGATAGCGCGTCGCCGAAGCCCGTGGTGCACCGCGGACCGGCTCTGGGCCACAATTCCGGCCCCCGACA
CGATTCCACGGAGACACGTG

Downstream 100 bases:

>100_bases
GCACCGACGGAACCGCCTGTTCGCCCCGGCCCTGGCCGCAGGTGCCGGCCTGCTACGGCTGGCTGTCGCTCGACCGCCGC
GGGCGCTGGCGCCTGCAGGG

Product: enoyl-CoA hydratase/isomerase

Products: NA

Alternate protein names: 3-hydroxypropionyl-CoA dehydratase [H]

Number of amino acids: Translated: 372; Mature: 371

Protein sequence:

>372_residues
MTAAVLLREIPTACGRRFGHATLNAERALNALSLEMIDLLAPQLDAWAADPDIVGVVLDGSGDKAFCAGGDVAALYRALR
AHDGDAPPQAVTDFFEREYRLDYRIHTYPKPLLCWGHGIVMGGGIGLLAGASHRVATLQTRMAMPEITIGLYPDVGGSWF
LPRMPGRAGLFLALTGAPLNAADARFAGLADFVLDHGARGGVLAALGATRWAGDAAADRLRLDHLLGEFSVREGMPAAPL
RTHLDRIEAVVGRGSLAEIAVRLHALAADPDPWLAAAAGSFVRGAPSSAALSLELWRRARHLSLAEVFRLEYIVSVAATG
RADFVEGVRALLIDKDRKPRWQHADVGAVDTAFIADNFRARFDGAHPLADLA

Sequences:

>Translated_372_residues
MTAAVLLREIPTACGRRFGHATLNAERALNALSLEMIDLLAPQLDAWAADPDIVGVVLDGSGDKAFCAGGDVAALYRALR
AHDGDAPPQAVTDFFEREYRLDYRIHTYPKPLLCWGHGIVMGGGIGLLAGASHRVATLQTRMAMPEITIGLYPDVGGSWF
LPRMPGRAGLFLALTGAPLNAADARFAGLADFVLDHGARGGVLAALGATRWAGDAAADRLRLDHLLGEFSVREGMPAAPL
RTHLDRIEAVVGRGSLAEIAVRLHALAADPDPWLAAAAGSFVRGAPSSAALSLELWRRARHLSLAEVFRLEYIVSVAATG
RADFVEGVRALLIDKDRKPRWQHADVGAVDTAFIADNFRARFDGAHPLADLA
>Mature_371_residues
TAAVLLREIPTACGRRFGHATLNAERALNALSLEMIDLLAPQLDAWAADPDIVGVVLDGSGDKAFCAGGDVAALYRALRA
HDGDAPPQAVTDFFEREYRLDYRIHTYPKPLLCWGHGIVMGGGIGLLAGASHRVATLQTRMAMPEITIGLYPDVGGSWFL
PRMPGRAGLFLALTGAPLNAADARFAGLADFVLDHGARGGVLAALGATRWAGDAAADRLRLDHLLGEFSVREGMPAAPLR
THLDRIEAVVGRGSLAEIAVRLHALAADPDPWLAAAAGSFVRGAPSSAALSLELWRRARHLSLAEVFRLEYIVSVAATGR
ADFVEGVRALLIDKDRKPRWQHADVGAVDTAFIADNFRARFDGAHPLADLA

Specific function: Plays a role in autotrophic carbon fixation via the 3- hydroxypropionate/4-hydroxybutyrate cycle. Catalyzes the reversible dehydration of 3-hydroxypropionyl-CoA to form acryloyl- CoA, and the reversible dehydration of (S)-3-hydroxybutyryl-CoA to form crot

COG id: COG1024

COG function: function code I; Enoyl-CoA hydratase/carnithine racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the enoyl-CoA hydratase/isomerase family [H]

Homologues:

Organism=Homo sapiens, GI37594471, Length=345, Percent_Identity=34.7826086956522, Blast_Score=206, Evalue=4e-53,
Organism=Homo sapiens, GI37594469, Length=303, Percent_Identity=33.6633663366337, Blast_Score=169, Evalue=3e-42,
Organism=Homo sapiens, GI194097323, Length=177, Percent_Identity=31.0734463276836, Blast_Score=71, Evalue=1e-12,
Organism=Escherichia coli, GI1788682, Length=171, Percent_Identity=28.6549707602339, Blast_Score=65, Evalue=8e-12,
Organism=Escherichia coli, GI1787660, Length=176, Percent_Identity=35.2272727272727, Blast_Score=65, Evalue=1e-11,
Organism=Escherichia coli, GI1787659, Length=198, Percent_Identity=29.2929292929293, Blast_Score=64, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI25144160, Length=337, Percent_Identity=37.6854599406528, Blast_Score=220, Evalue=9e-58,
Organism=Caenorhabditis elegans, GI25144157, Length=337, Percent_Identity=37.6854599406528, Blast_Score=220, Evalue=1e-57,
Organism=Saccharomyces cerevisiae, GI6320241, Length=341, Percent_Identity=28.4457478005865, Blast_Score=122, Evalue=7e-29,
Organism=Drosophila melanogaster, GI28571729, Length=341, Percent_Identity=35.7771260997067, Blast_Score=191, Evalue=7e-49,
Organism=Drosophila melanogaster, GI28571730, Length=341, Percent_Identity=35.7771260997067, Blast_Score=191, Evalue=7e-49,
Organism=Drosophila melanogaster, GI20129971, Length=181, Percent_Identity=30.3867403314917, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24653477, Length=181, Percent_Identity=30.3867403314917, Blast_Score=74, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014748
- InterPro:   IPR001753
- InterPro:   IPR018376 [H]

Pfam domain/function: PF00378 ECH [H]

EC number: =4.2.1.116 [H]

Molecular weight: Translated: 39651; Mature: 39520

Theoretical pI: Translated: 6.65; Mature: 6.65

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTAAVLLREIPTACGRRFGHATLNAERALNALSLEMIDLLAPQLDAWAADPDIVGVVLDG
CCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCHHCCCCCCCEEEEEEEC
SGDKAFCAGGDVAALYRALRAHDGDAPPQAVTDFFEREYRLDYRIHTYPKPLLCWGHGIV
CCCEEEECCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHEEEEEEECCCCCEEEECCCEE
MGGGIGLLAGASHRVATLQTRMAMPEITIGLYPDVGGSWFLPRMPGRAGLFLALTGAPLN
EECCHHEECCCCCHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCCCCCEEEEEECCCCC
AADARFAGLADFVLDHGARGGVLAALGATRWAGDAAADRLRLDHLLGEFSVREGMPAAPL
CCCHHHHHHHHHHHHCCCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHH
RTHLDRIEAVVGRGSLAEIAVRLHALAADPDPWLAAAAGSFVRGAPSSAALSLELWRRAR
HHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCHHHHHCCHHHCCCCCCCEEEHHHHHHHH
HLSLAEVFRLEYIVSVAATGRADFVEGVRALLIDKDRKPRWQHADVGAVDTAFIADNFRA
HCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHCCCHH
RFDGAHPLADLA
HCCCCCCHHCCC
>Mature Secondary Structure 
TAAVLLREIPTACGRRFGHATLNAERALNALSLEMIDLLAPQLDAWAADPDIVGVVLDG
CHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCHHCCCCCCCEEEEEEEC
SGDKAFCAGGDVAALYRALRAHDGDAPPQAVTDFFEREYRLDYRIHTYPKPLLCWGHGIV
CCCEEEECCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHEEEEEEECCCCCEEEECCCEE
MGGGIGLLAGASHRVATLQTRMAMPEITIGLYPDVGGSWFLPRMPGRAGLFLALTGAPLN
EECCHHEECCCCCHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCCCCCEEEEEECCCCC
AADARFAGLADFVLDHGARGGVLAALGATRWAGDAAADRLRLDHLLGEFSVREGMPAAPL
CCCHHHHHHHHHHHHCCCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHH
RTHLDRIEAVVGRGSLAEIAVRLHALAADPDPWLAAAAGSFVRGAPSSAALSLELWRRAR
HHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCHHHHHCCHHHCCCCCCCEEEHHHHHHHH
HLSLAEVFRLEYIVSVAATGRADFVEGVRALLIDKDRKPRWQHADVGAVDTAFIADNFRA
HCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHCCCHH
RFDGAHPLADLA
HCCCCCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA