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The map label for this gene is glpC [H]

Identifier: 119896354

GI number: 119896354

Start: 73627

End: 75072

Strand: Direct

Name: glpC [H]

Synonym: azo0062

Alternate gene names: 119896354

Gene position: 73627-75072 (Clockwise)

Preceding gene: 119896350

Following gene: 119896355

Centisome position: 1.68

GC content: 71.16

Gene sequence:

>1446_bases
ATGAATGGCACTGCGCTTGCTTCGTATCCCTGCGGTTTACCGCCTTGCCTGTTCCGCCCCCCGGCGCCCGAGCCGGACCG
CATTCGACGCGCGCACATGAAACATCAACTCGACTGGTCGTCCTACGAAACCGCGGGGCAGGGCGATGCCTATGCCGGCA
TTCCCGCGACCGGGGGCGACTTCGCCAAGGCGGTGGCGGTGTGCATCAGCGACCGCAGCTGCCTGAAGAAGCCGAAGGGC
GTGATGTGTCCGAGCTTTCGCGCCACCGACGAGGCAGCGCACTCGCCCGGTGAGCGGGTGAAGGTGCTGAAGGACGCCCT
GAACGGCGAATTCGGCGACAACCCGTTTGCCGACCCGCGCATCCGTGATGCGCTGGAGCTGTGCGTCGGCTGCAAGGGCT
GCAAGCGCGAGTGCGCCAACCAGGTGGACATGGCGGCGATCAAGATCGAGGTGCTCGCCCAGCGCAACGCCGCGCTCGGT
GTCAGCCCGCGCGACCGCCTGTTCGCCAGCCTGCCGCGTCTGCTCGGCGAACGGCGCTGGCTCGCCAGCTTGGTGCGCTG
GCGCAACCGCAGCCCCTGGCTCGCGCGGCTGGGCGAACGCTGGCTGGGCATCGCCGCCGGGCGGGCGCTGCCGGAACCCG
CTGCCCAGCCCTACGCGGCCCCCGCGGCACGCGCCACCGCCCCGGCGGACACGGCCGATGACCGCCGCGTGATCCTCTTC
GTCGACACCTTCGCACGCCACTTCGAACCCGAAATCGCCGCCGCCGCCCACGCGGTGCTCGACGCCGCCGGCTACCAGGT
CGAGGTACTGGCGCCGGCCGCCGCCGACGGCGAGCAGCGCCCGCTGTGCTGCGGCCGCACCTGGCTCTCGCTCGGCCAGG
TCGACGCGGCCCGCGCCGAGGCGCGCCGGATGCAGGCGGCGCTGCGGCCGGCGCTGGAAAAGGGCTGGCCGGTGGTGGGA
CTGGAACCGTCCTGCATCCTGTCGCTGCGCGACGACCACCTCAAGCTCGGCCTTGGCGCCGAAGCCGAGGCGCTCGCGAA
GCAGGTCTACCTGTTCGAGGAATTCATCGCCCGCGAGCACGACCGCAAGCGCCTCCAGCTCAAGCTCAAACCCCTCGCCG
GCGGCAAGACCCTGGTGCATGGGCACTGCCACCAGAAGGCGGTGGGTGCGATGAAGTCGCTGCGCAAGGTGCTGCGCCTG
ATCCCCGAATTCGACTTCGAATTCGTCGAGGCCAGCTGCTGCGGCATGGCCGGGCATTTCGGCCTCGAGGCCGAGCACGC
CGAAATCTCGCGCCGGATGGCCGAACTCGACCTGCTGCCGGCGCTGCGCGCGGCGCCCGACGCGCCGGTGCTCGCCAACG
GCTTTTCCTGTCGCCACCAGATCCGCGAAGGCGTGGCGCGCCAACCCCGGCACGTGGCCCTGCTGCTGCAGGCCGCCCTC
GCCTGA

Upstream 100 bases:

>100_bases
ACGCGGCAGGGCTGGGCGCACATCCGACGCCAAAACCCGCAGTGGGCTGTCGGCTTTGCTCCAATCCGCCCGGCGCCGGC
CGATCAAGCCTTTGATTCCT

Downstream 100 bases:

>100_bases
TCCGGAGATCCCGCCCATGTCCGATTCGTCCGATGCCTTCCGCGCCGCCGGCGCCCTTCCTATCCATCCCGCCACCGCCG
CGGTGCCAGCCGCCGACATC

Product: hypothetical protein

Products: FADH2; dihydroxy-acetone-phosphate [C]

Alternate protein names: G-3-P dehydrogenase [H]

Number of amino acids: Translated: 481; Mature: 481

Protein sequence:

>481_residues
MNGTALASYPCGLPPCLFRPPAPEPDRIRRAHMKHQLDWSSYETAGQGDAYAGIPATGGDFAKAVAVCISDRSCLKKPKG
VMCPSFRATDEAAHSPGERVKVLKDALNGEFGDNPFADPRIRDALELCVGCKGCKRECANQVDMAAIKIEVLAQRNAALG
VSPRDRLFASLPRLLGERRWLASLVRWRNRSPWLARLGERWLGIAAGRALPEPAAQPYAAPAARATAPADTADDRRVILF
VDTFARHFEPEIAAAAHAVLDAAGYQVEVLAPAAADGEQRPLCCGRTWLSLGQVDAARAEARRMQAALRPALEKGWPVVG
LEPSCILSLRDDHLKLGLGAEAEALAKQVYLFEEFIAREHDRKRLQLKLKPLAGGKTLVHGHCHQKAVGAMKSLRKVLRL
IPEFDFEFVEASCCGMAGHFGLEAEHAEISRRMAELDLLPALRAAPDAPVLANGFSCRHQIREGVARQPRHVALLLQAAL
A

Sequences:

>Translated_481_residues
MNGTALASYPCGLPPCLFRPPAPEPDRIRRAHMKHQLDWSSYETAGQGDAYAGIPATGGDFAKAVAVCISDRSCLKKPKG
VMCPSFRATDEAAHSPGERVKVLKDALNGEFGDNPFADPRIRDALELCVGCKGCKRECANQVDMAAIKIEVLAQRNAALG
VSPRDRLFASLPRLLGERRWLASLVRWRNRSPWLARLGERWLGIAAGRALPEPAAQPYAAPAARATAPADTADDRRVILF
VDTFARHFEPEIAAAAHAVLDAAGYQVEVLAPAAADGEQRPLCCGRTWLSLGQVDAARAEARRMQAALRPALEKGWPVVG
LEPSCILSLRDDHLKLGLGAEAEALAKQVYLFEEFIAREHDRKRLQLKLKPLAGGKTLVHGHCHQKAVGAMKSLRKVLRL
IPEFDFEFVEASCCGMAGHFGLEAEHAEISRRMAELDLLPALRAAPDAPVLANGFSCRHQIREGVARQPRHVALLLQAAL
A
>Mature_481_residues
MNGTALASYPCGLPPCLFRPPAPEPDRIRRAHMKHQLDWSSYETAGQGDAYAGIPATGGDFAKAVAVCISDRSCLKKPKG
VMCPSFRATDEAAHSPGERVKVLKDALNGEFGDNPFADPRIRDALELCVGCKGCKRECANQVDMAAIKIEVLAQRNAALG
VSPRDRLFASLPRLLGERRWLASLVRWRNRSPWLARLGERWLGIAAGRALPEPAAQPYAAPAARATAPADTADDRRVILF
VDTFARHFEPEIAAAAHAVLDAAGYQVEVLAPAAADGEQRPLCCGRTWLSLGQVDAARAEARRMQAALRPALEKGWPVVG
LEPSCILSLRDDHLKLGLGAEAEALAKQVYLFEEFIAREHDRKRLQLKLKPLAGGKTLVHGHCHQKAVGAMKSLRKVLRL
IPEFDFEFVEASCCGMAGHFGLEAEHAEISRRMAELDLLPALRAAPDAPVLANGFSCRHQIREGVARQPRHVALLLQAAL
A

Specific function: Electron transfer protein; may also function as the membrane anchor for the glpAB dimer [H]

COG id: COG0247

COG function: function code C; Fe-S oxidoreductase

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein. Note=Loosely bound to the cytoplasmic membrane often occurring in vesicles associated with fumarate reductase [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 4Fe-4S ferredoxin-type domains [H]

Homologues:

Organism=Escherichia coli, GI1788576, Length=366, Percent_Identity=25.6830601092896, Blast_Score=98, Evalue=1e-21,
Organism=Escherichia coli, GI1787977, Length=434, Percent_Identity=21.889400921659, Blast_Score=90, Evalue=4e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017896
- InterPro:   IPR017900
- InterPro:   IPR004017
- InterPro:   IPR012285
- InterPro:   IPR017753
- InterPro:   IPR009051 [H]

Pfam domain/function: PF02754 CCG [H]

EC number: NA

Molecular weight: Translated: 52290; Mature: 52290

Theoretical pI: Translated: 8.54; Mature: 8.54

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.3 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
3.3 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNGTALASYPCGLPPCLFRPPAPEPDRIRRAHMKHQLDWSSYETAGQGDAYAGIPATGGD
CCCCEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHH
FAKAVAVCISDRSCLKKPKGVMCPSFRATDEAAHSPGERVKVLKDALNGEFGDNPFADPR
HHHHHHHHHCCHHHHCCCCCCCCCCCCCCCHHHCCCHHHHHHHHHHHCCCCCCCCCCCHH
IRDALELCVGCKGCKRECANQVDMAAIKIEVLAQRNAALGVSPRDRLFASLPRLLGERRW
HHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHH
LASLVRWRNRSPWLARLGERWLGIAAGRALPEPAAQPYAAPAARATAPADTADDRRVILF
HHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEE
VDTFARHFEPEIAAAAHAVLDAAGYQVEVLAPAAADGEQRPLCCGRTWLSLGQVDAARAE
EEHHHHHCCHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCEECCHHHHHHCCHHHHHHH
ARRMQAALRPALEKGWPVVGLEPSCILSLRDDHLKLGLGAEAEALAKQVYLFEEFIAREH
HHHHHHHHHHHHHHCCCEECCCHHEEEEECCCCEEECCCCCHHHHHHHHHHHHHHHHHHC
DRKRLQLKLKPLAGGKTLVHGHCHQKAVGAMKSLRKVLRLIPEFDFEFVEASCCGMAGHF
CCCEEEEEEEECCCCCEEEECCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCHHCC
GLEAEHAEISRRMAELDLLPALRAAPDAPVLANGFSCRHQIREGVARQPRHVALLLQAAL
CCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEECCHHHHHHHHHHHHCCCHHHHHHHHHHH
A
C
>Mature Secondary Structure
MNGTALASYPCGLPPCLFRPPAPEPDRIRRAHMKHQLDWSSYETAGQGDAYAGIPATGGD
CCCCEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHH
FAKAVAVCISDRSCLKKPKGVMCPSFRATDEAAHSPGERVKVLKDALNGEFGDNPFADPR
HHHHHHHHHCCHHHHCCCCCCCCCCCCCCCHHHCCCHHHHHHHHHHHCCCCCCCCCCCHH
IRDALELCVGCKGCKRECANQVDMAAIKIEVLAQRNAALGVSPRDRLFASLPRLLGERRW
HHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHH
LASLVRWRNRSPWLARLGERWLGIAAGRALPEPAAQPYAAPAARATAPADTADDRRVILF
HHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEE
VDTFARHFEPEIAAAAHAVLDAAGYQVEVLAPAAADGEQRPLCCGRTWLSLGQVDAARAE
EEHHHHHCCHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCEECCHHHHHHCCHHHHHHH
ARRMQAALRPALEKGWPVVGLEPSCILSLRDDHLKLGLGAEAEALAKQVYLFEEFIAREH
HHHHHHHHHHHHHHCCCEECCCHHEEEEECCCCEEECCCCCHHHHHHHHHHHHHHHHHHC
DRKRLQLKLKPLAGGKTLVHGHCHQKAVGAMKSLRKVLRLIPEFDFEFVEASCCGMAGHF
CCCEEEEEEEECCCCCEEEECCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCHHCC
GLEAEHAEISRRMAELDLLPALRAAPDAPVLANGFSCRHQIREGVARQPRHVALLLQAAL
CCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEECCHHHHHHHHHHHHCCCHHHHHHHHHHH
A
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: Fe [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: FAD; glycerol-3-phosphate [C]

Specific reaction: FAD + glycerol-3-phosphate = FADH2 + dihydroxy-acetone-phosphate [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]