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The map label for this gene is dehH [C]

Identifier: 119896338

GI number: 119896338

Start: 51590

End: 52516

Strand: Reverse

Name: dehH [C]

Synonym: azo0046

Alternate gene names: 119896338

Gene position: 52516-51590 (Counterclockwise)

Preceding gene: 119896339

Following gene: 119896337

Centisome position: 1.2

GC content: 71.74

Gene sequence:

>927_bases
ATGTCCGTAGTCACCGAGGTCGCCGCCGCAGCCGATGCCGTGCTGTTTCCCGGCTTTGCCCGTCGCCGGATCGAGGTCGG
CGCGGGCGTCTCGATTCCCTGCGTGAGCGGCGGCGACGGCCCGCCGCTGTTGCTGCTGCACGGCCACCCGCAGACGCACG
CGATCTGGCACAAGGTGGCGGCCCGACTCGCGCGCCACTTCACCGTGGTGGCGAGCGATCTGCGCGGCTACGGTGACGCC
AGCCGTCCGGCGACCACCGCCGACCACGTCCGCTATTCCAAGCGCGAAATGGCGGCCGATCAGGTGGCGCTGATGCGCGC
GCTCGGCCACGACCGTTTCAGCGTGCTGGCCCACGACCGTGGCGCGCGCGTCGCCCATCGCCTCGCCGCCGATCATCCAC
AGGCGGTGAGCCGCATGGTGCTGCTCGACATCGCCCCCACGCTGGCGATGTACGAGCAGACCACCGAGACCTTTGCGCGC
GCTTACTGGCACTGGTTCTTCCTGATCCAGCGCGCGCCACTGCCGGAACGCCTGATCGAAGCCGACCCCACTGCCTACCT
GCGCGACGTGATGGGCAGCCGCCACGCCGGGCTCGCCGCCTTCGACCCGACCGCCTTTGCCGAATACGCGCGCTGCCTGT
CGCAGCCCGGCGCGGCGCACAGCCTGTGCGAGGACTACCGCGCCGCCGCCACCATCGATCTCGAACACGACCGCGCCGAC
CGCGCCGCCGGGCGTCGGCTGGCGATGCCGCTGCAGGTGCTGTGGGGACAGAGCGGCATCGTGCAGCGCTGCTTCCGCCC
GCTGGACGAATGGCGCCGCGTCGCGGACGACGTGCGCGGCGGCACCCTGCCCTGCGGCCACTACATTCCCGAGGAAGCGC
CGGCGGAACTGCTGGCCGCCGCGCTGCCCTTTCTGCTCGCGGATTGA

Upstream 100 bases:

>100_bases
AACTGACCCTGGTGCGGCAGTTCGTCTATCCGTGAGCGCTTTGCGGCGGCCGGCGCGGAGGCGATACTCGGCCTCCGTCC
CCCGCCGCGAGGATTCGCCA

Downstream 100 bases:

>100_bases
GCGCCGTCCGCCGCTTGCCGATGTCGCGTCCGGCCGATAGGTTCCGGCGGGTGTCCATCCCGTCCGCCGTGCTTCCCGTG
AATCCCCGCCCCCCCGCCGG

Product: haloacetate dehalogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 308; Mature: 307

Protein sequence:

>308_residues
MSVVTEVAAAADAVLFPGFARRRIEVGAGVSIPCVSGGDGPPLLLLHGHPQTHAIWHKVAARLARHFTVVASDLRGYGDA
SRPATTADHVRYSKREMAADQVALMRALGHDRFSVLAHDRGARVAHRLAADHPQAVSRMVLLDIAPTLAMYEQTTETFAR
AYWHWFFLIQRAPLPERLIEADPTAYLRDVMGSRHAGLAAFDPTAFAEYARCLSQPGAAHSLCEDYRAAATIDLEHDRAD
RAAGRRLAMPLQVLWGQSGIVQRCFRPLDEWRRVADDVRGGTLPCGHYIPEEAPAELLAAALPFLLAD

Sequences:

>Translated_308_residues
MSVVTEVAAAADAVLFPGFARRRIEVGAGVSIPCVSGGDGPPLLLLHGHPQTHAIWHKVAARLARHFTVVASDLRGYGDA
SRPATTADHVRYSKREMAADQVALMRALGHDRFSVLAHDRGARVAHRLAADHPQAVSRMVLLDIAPTLAMYEQTTETFAR
AYWHWFFLIQRAPLPERLIEADPTAYLRDVMGSRHAGLAAFDPTAFAEYARCLSQPGAAHSLCEDYRAAATIDLEHDRAD
RAAGRRLAMPLQVLWGQSGIVQRCFRPLDEWRRVADDVRGGTLPCGHYIPEEAPAELLAAALPFLLAD
>Mature_307_residues
SVVTEVAAAADAVLFPGFARRRIEVGAGVSIPCVSGGDGPPLLLLHGHPQTHAIWHKVAARLARHFTVVASDLRGYGDAS
RPATTADHVRYSKREMAADQVALMRALGHDRFSVLAHDRGARVAHRLAADHPQAVSRMVLLDIAPTLAMYEQTTETFARA
YWHWFFLIQRAPLPERLIEADPTAYLRDVMGSRHAGLAAFDPTAFAEYARCLSQPGAAHSLCEDYRAAATIDLEHDRADR
AAGRRLAMPLQVLWGQSGIVQRCFRPLDEWRRVADDVRGGTLPCGHYIPEEAPAELLAAALPFLLAD

Specific function: Catalyzes the hydrolytic defluorination of fluoroacetate to produce glycolate. Has low activity towards chloroacetate [H]

COG id: COG0596

COG function: function code R; Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AB hydrolase superfamily. Epoxide hydrolase family [H]

Homologues:

Organism=Homo sapiens, GI218777840, Length=271, Percent_Identity=28.4132841328413, Blast_Score=101, Evalue=1e-21,
Organism=Homo sapiens, GI13376164, Length=271, Percent_Identity=28.4132841328413, Blast_Score=101, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI17554012, Length=228, Percent_Identity=26.7543859649123, Blast_Score=82, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI17562298, Length=193, Percent_Identity=24.8704663212435, Blast_Score=70, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000073
- InterPro:   IPR000639 [H]

Pfam domain/function: PF00561 Abhydrolase_1 [H]

EC number: =3.8.1.3 [H]

Molecular weight: Translated: 33746; Mature: 33615

Theoretical pI: Translated: 7.24; Mature: 7.24

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVVTEVAAAADAVLFPGFARRRIEVGAGVSIPCVSGGDGPPLLLLHGHPQTHAIWHKVA
CCHHHHHHHHHHHHHCCCHHHHHEEECCCCEEEECCCCCCCCEEEEECCCCHHHHHHHHH
ARLARHFTVVASDLRGYGDASRPATTADHVRYSKREMAADQVALMRALGHDRFSVLAHDR
HHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCC
GARVAHRLAADHPQAVSRMVLLDIAPTLAMYEQTTETFARAYWHWFFLIQRAPLPERLIE
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHC
ADPTAYLRDVMGSRHAGLAAFDPTAFAEYARCLSQPGAAHSLCEDYRAAATIDLEHDRAD
CCCHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHEEEECCCCHHH
RAAGRRLAMPLQVLWGQSGIVQRCFRPLDEWRRVADDVRGGTLPCGHYIPEEAPAELLAA
HHHCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHH
ALPFLLAD
HHHHHHCC
>Mature Secondary Structure 
SVVTEVAAAADAVLFPGFARRRIEVGAGVSIPCVSGGDGPPLLLLHGHPQTHAIWHKVA
CHHHHHHHHHHHHHCCCHHHHHEEECCCCEEEECCCCCCCCEEEEECCCCHHHHHHHHH
ARLARHFTVVASDLRGYGDASRPATTADHVRYSKREMAADQVALMRALGHDRFSVLAHDR
HHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCC
GARVAHRLAADHPQAVSRMVLLDIAPTLAMYEQTTETFARAYWHWFFLIQRAPLPERLIE
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHC
ADPTAYLRDVMGSRHAGLAAFDPTAFAEYARCLSQPGAAHSLCEDYRAAATIDLEHDRAD
CCCHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHEEEECCCCHHH
RAAGRRLAMPLQVLWGQSGIVQRCFRPLDEWRRVADDVRGGTLPCGHYIPEEAPAELLAA
HHHCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHH
ALPFLLAD
HHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA