BacMap

Definition	Azoarcus sp. BH72 chromosome, complete genome.
Accession	NC_008702
Length	4,376,040

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The map label for this gene is fabG3 [H]

Identifier: 119896330

GI number: 119896330

Start: 42527

End: 43336

Strand: Direct

Name: fabG3 [H]

Synonym: azo0038

Alternate gene names: 119896330

Gene position: 42527-43336 (Clockwise)

Preceding gene: 119896329

Following gene: 119896331

Centisome position: 0.97

GC content: 70.74

Gene sequence:

>810_bases
ATGACCACCACGATCGAAACCCGCCTGATGGACCTCACCGGCCGCGTCGCCTTCGTCACCGGCGGCGCCTCCGGCATCGG
CCGCGCCACCGCGCACGCGCTCGCGGCGCAGGGCGCCCGCGTCATCGTCGCCGACATCAACGAAACCGGCGGCTGGGAAA
CCGCCGACGCCATCGGCACCGCCGCCGGCTTCGTGCACCTGGACGTCACCGAAGAGACCGCCTGGTGCCGCGCGCTCGAC
TACGTCATCTCCACCGAAGGCCGCCTCGACATCCTCGCCAACGTCGCCGGCATCGGCCTGGGTGGCGACTTCGAGGACCT
GGCGCTGGCCGACTGGAACCGCCTCATGGCGGTCAACGCCACCGGCCCCTTCCTCGGCTGCAAGCACGCCATCCGCGCCA
TGGCCGGCAGCGGCCGCCCCGGCGCCATCATCAACGTCGGCTCCATCGCCGCCACCCACGCCGCGCCGGATCTGGGCGGC
TACTGCGCCAGCAAGGGCGCGCTGCGCATGCTCAGCAAATCGGTAGCGCTGTACTGCGCCCACAAGGGCTACCCGATCCG
CTGCAACGCGGTGCATCCCACCTATGTGGATAGCGAAATGCTGGACCCGATCGCGGCGCTGTATGGGAGCCGGGAAGCGA
TGGTGCAGGCGATGGCGCGGCTGGTGCCGGTGGGAAGGTTGGCCAAGCCGGCGGATGTCGCGGCGGCGGTGGTGTATCTG
GCGTCGGACGCGGCGGGGATGGTGACCGGGACCGAGCTGTTCGTCGACGGCGGGCAGACGGCTGGGATTGCGCCGTCGCA
TTTCGGGTGA

Upstream 100 bases:

>100_bases
GCCTGCTGCTGCCCGCCACCCGGCCGGCGGCGGCAACCGCTACCCCCCGACACCCCGAACCCCATCTTCGCCTTGCCGAC
GCGCAAAGGAGCTGAACACC

Downstream 100 bases:

>100_bases
GGGGCGGCGCGTGCTACAGGGCCATGGGGTTTCGACCGCGGCCGGCGCGCACACCGCCGGTCGGCGATCACGGCGCGAAA
CAACGATAATGGCGCCCACT

Product: short-chain dehydrogenase family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 269; Mature: 268

Protein sequence:

>269_residues
MTTTIETRLMDLTGRVAFVTGGASGIGRATAHALAAQGARVIVADINETGGWETADAIGTAAGFVHLDVTEETAWCRALD
YVISTEGRLDILANVAGIGLGGDFEDLALADWNRLMAVNATGPFLGCKHAIRAMAGSGRPGAIINVGSIAATHAAPDLGG
YCASKGALRMLSKSVALYCAHKGYPIRCNAVHPTYVDSEMLDPIAALYGSREAMVQAMARLVPVGRLAKPADVAAAVVYL
ASDAAGMVTGTELFVDGGQTAGIAPSHFG

Sequences:

>Translated_269_residues
MTTTIETRLMDLTGRVAFVTGGASGIGRATAHALAAQGARVIVADINETGGWETADAIGTAAGFVHLDVTEETAWCRALD
YVISTEGRLDILANVAGIGLGGDFEDLALADWNRLMAVNATGPFLGCKHAIRAMAGSGRPGAIINVGSIAATHAAPDLGG
YCASKGALRMLSKSVALYCAHKGYPIRCNAVHPTYVDSEMLDPIAALYGSREAMVQAMARLVPVGRLAKPADVAAAVVYL
ASDAAGMVTGTELFVDGGQTAGIAPSHFG
>Mature_268_residues
TTTIETRLMDLTGRVAFVTGGASGIGRATAHALAAQGARVIVADINETGGWETADAIGTAAGFVHLDVTEETAWCRALDY
VISTEGRLDILANVAGIGLGGDFEDLALADWNRLMAVNATGPFLGCKHAIRAMAGSGRPGAIINVGSIAATHAAPDLGGY
CASKGALRMLSKSVALYCAHKGYPIRCNAVHPTYVDSEMLDPIAALYGSREAMVQAMARLVPVGRLAKPADVAAAVVYLA
SDAAGMVTGTELFVDGGQTAGIAPSHFG

Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]

COG id: COG1028

COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI7705925, Length=255, Percent_Identity=34.5098039215686, Blast_Score=109, Evalue=2e-24,
Organism=Homo sapiens, GI15277342, Length=270, Percent_Identity=31.1111111111111, Blast_Score=108, Evalue=6e-24,
Organism=Homo sapiens, GI66933014, Length=248, Percent_Identity=34.6774193548387, Blast_Score=102, Evalue=5e-22,
Organism=Homo sapiens, GI40254992, Length=244, Percent_Identity=31.9672131147541, Blast_Score=98, Evalue=1e-20,
Organism=Homo sapiens, GI59889578, Length=236, Percent_Identity=31.7796610169492, Blast_Score=91, Evalue=9e-19,
Organism=Homo sapiens, GI31542939, Length=204, Percent_Identity=31.3725490196078, Blast_Score=90, Evalue=2e-18,
Organism=Homo sapiens, GI4758504, Length=239, Percent_Identity=32.2175732217573, Blast_Score=88, Evalue=7e-18,
Organism=Homo sapiens, GI32483357, Length=258, Percent_Identity=27.906976744186, Blast_Score=85, Evalue=9e-17,
Organism=Homo sapiens, GI83715985, Length=180, Percent_Identity=34.4444444444444, Blast_Score=83, Evalue=3e-16,
Organism=Homo sapiens, GI19923817, Length=259, Percent_Identity=28.957528957529, Blast_Score=83, Evalue=3e-16,
Organism=Homo sapiens, GI5031737, Length=268, Percent_Identity=29.4776119402985, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI224922801, Length=176, Percent_Identity=31.8181818181818, Blast_Score=76, Evalue=3e-14,
Organism=Homo sapiens, GI126723750, Length=261, Percent_Identity=26.4367816091954, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI33667109, Length=208, Percent_Identity=31.7307692307692, Blast_Score=66, Evalue=3e-11,
Organism=Homo sapiens, GI50726952, Length=209, Percent_Identity=28.7081339712919, Blast_Score=65, Evalue=7e-11,
Organism=Escherichia coli, GI1787335, Length=249, Percent_Identity=35.3413654618474, Blast_Score=125, Evalue=2e-30,
Organism=Escherichia coli, GI1786812, Length=257, Percent_Identity=32.295719844358, Blast_Score=111, Evalue=6e-26,
Organism=Escherichia coli, GI1790717, Length=253, Percent_Identity=30.4347826086957, Blast_Score=110, Evalue=9e-26,
Organism=Escherichia coli, GI1788459, Length=249, Percent_Identity=33.7349397590361, Blast_Score=110, Evalue=1e-25,
Organism=Escherichia coli, GI87082100, Length=255, Percent_Identity=32.9411764705882, Blast_Score=107, Evalue=8e-25,
Organism=Escherichia coli, GI2367175, Length=252, Percent_Identity=34.9206349206349, Blast_Score=106, Evalue=2e-24,
Organism=Escherichia coli, GI87082160, Length=254, Percent_Identity=32.2834645669291, Blast_Score=98, Evalue=7e-22,
Organism=Escherichia coli, GI1787905, Length=252, Percent_Identity=31.7460317460317, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI1789208, Length=251, Percent_Identity=28.6852589641434, Blast_Score=89, Evalue=3e-19,
Organism=Escherichia coli, GI1789057, Length=259, Percent_Identity=29.3436293436293, Blast_Score=84, Evalue=7e-18,
Organism=Escherichia coli, GI1789378, Length=258, Percent_Identity=31.7829457364341, Blast_Score=82, Evalue=3e-17,
Organism=Escherichia coli, GI2367365, Length=247, Percent_Identity=28.7449392712551, Blast_Score=73, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17555706, Length=248, Percent_Identity=33.0645161290323, Blast_Score=120, Evalue=9e-28,
Organism=Caenorhabditis elegans, GI25147288, Length=250, Percent_Identity=32.4, Blast_Score=106, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI17560676, Length=261, Percent_Identity=30.2681992337165, Blast_Score=99, Evalue=3e-21,
Organism=Caenorhabditis elegans, GI115534694, Length=253, Percent_Identity=30.8300395256917, Blast_Score=95, Evalue=4e-20,
Organism=Caenorhabditis elegans, GI17531453, Length=269, Percent_Identity=30.1115241635688, Blast_Score=95, Evalue=5e-20,
Organism=Caenorhabditis elegans, GI17562908, Length=272, Percent_Identity=30.8823529411765, Blast_Score=94, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI17562906, Length=264, Percent_Identity=29.1666666666667, Blast_Score=90, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI193204405, Length=265, Percent_Identity=29.4339622641509, Blast_Score=89, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI193203117, Length=202, Percent_Identity=31.6831683168317, Blast_Score=88, Evalue=4e-18,
Organism=Caenorhabditis elegans, GI193203115, Length=200, Percent_Identity=32.5, Blast_Score=88, Evalue=4e-18,
Organism=Caenorhabditis elegans, GI17538182, Length=261, Percent_Identity=30.2681992337165, Blast_Score=87, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI71994604, Length=255, Percent_Identity=30.1960784313725, Blast_Score=86, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17559104, Length=262, Percent_Identity=28.2442748091603, Blast_Score=83, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17562910, Length=280, Percent_Identity=27.1428571428571, Blast_Score=81, Evalue=6e-16,
Organism=Caenorhabditis elegans, GI17561402, Length=259, Percent_Identity=28.1853281853282, Blast_Score=80, Evalue=8e-16,
Organism=Caenorhabditis elegans, GI17560220, Length=266, Percent_Identity=28.1954887218045, Blast_Score=79, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI17560332, Length=269, Percent_Identity=27.5092936802974, Blast_Score=77, Evalue=7e-15,
Organism=Caenorhabditis elegans, GI17562904, Length=262, Percent_Identity=26.3358778625954, Blast_Score=77, Evalue=9e-15,
Organism=Caenorhabditis elegans, GI17564282, Length=240, Percent_Identity=27.9166666666667, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI71994600, Length=252, Percent_Identity=27.3809523809524, Blast_Score=75, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17560150, Length=269, Percent_Identity=26.3940520446097, Blast_Score=75, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI17563726, Length=267, Percent_Identity=25.8426966292135, Blast_Score=72, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17551412, Length=267, Percent_Identity=26.9662921348315, Blast_Score=72, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17508651, Length=249, Percent_Identity=30.1204819277108, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17538480, Length=263, Percent_Identity=27.7566539923954, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17538486, Length=268, Percent_Identity=27.2388059701493, Blast_Score=67, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI17562990, Length=263, Percent_Identity=26.2357414448669, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI72000259, Length=269, Percent_Identity=26.7657992565056, Blast_Score=65, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17536025, Length=273, Percent_Identity=27.4725274725275, Blast_Score=64, Evalue=7e-11,
Organism=Saccharomyces cerevisiae, GI6324126, Length=255, Percent_Identity=27.4509803921569, Blast_Score=76, Evalue=6e-15,
Organism=Drosophila melanogaster, GI23397609, Length=251, Percent_Identity=32.2709163346614, Blast_Score=101, Evalue=4e-22,
Organism=Drosophila melanogaster, GI28571526, Length=257, Percent_Identity=32.6848249027237, Blast_Score=101, Evalue=5e-22,
Organism=Drosophila melanogaster, GI24639444, Length=250, Percent_Identity=29.2, Blast_Score=97, Evalue=9e-21,
Organism=Drosophila melanogaster, GI17737361, Length=258, Percent_Identity=32.5581395348837, Blast_Score=97, Evalue=1e-20,
Organism=Drosophila melanogaster, GI21357041, Length=256, Percent_Identity=32.03125, Blast_Score=95, Evalue=4e-20,
Organism=Drosophila melanogaster, GI24644339, Length=256, Percent_Identity=28.90625, Blast_Score=86, Evalue=2e-17,
Organism=Drosophila melanogaster, GI21355319, Length=256, Percent_Identity=31.25, Blast_Score=86, Evalue=3e-17,
Organism=Drosophila melanogaster, GI24644337, Length=254, Percent_Identity=30.7086614173228, Blast_Score=84, Evalue=1e-16,
Organism=Drosophila melanogaster, GI24643142, Length=252, Percent_Identity=29.3650793650794, Blast_Score=79, Evalue=4e-15,
Organism=Drosophila melanogaster, GI24641232, Length=239, Percent_Identity=28.8702928870293, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI28571387, Length=241, Percent_Identity=29.4605809128631, Blast_Score=66, Evalue=2e-11,
Organism=Drosophila melanogaster, GI21358495, Length=208, Percent_Identity=27.8846153846154, Blast_Score=65, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.1.1.53 [H]

Molecular weight: Translated: 27560; Mature: 27429

Theoretical pI: Translated: 5.87; Mature: 5.87

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTTIETRLMDLTGRVAFVTGGASGIGRATAHALAAQGARVIVADINETGGWETADAIGT
CCCCHHHHHHHHCCEEEEEECCCCCCHHHHHHHHHHCCCEEEEEECCCCCCCCCHHHHHH
AAGFVHLDVTEETAWCRALDYVISTEGRLDILANVAGIGLGGDFEDLALADWNRLMAVNA
HCCEEEEEECCCHHHHHHHHHHHCCCCCEEEEEEHHEECCCCCHHHHHHHCCCEEEEEEC
TGPFLGCKHAIRAMAGSGRPGAIINVGSIAATHAAPDLGGYCASKGALRMLSKSVALYCA
CCCCHHHHHHHHHHHCCCCCCEEEEECCEEECCCCCCCCCHHHCHHHHHHHHHHHEEEEE
HKGYPIRCNAVHPTYVDSEMLDPIAALYGSREAMVQAMARLVPVGRLAKPADVAAAVVYL
CCCCCEEECCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHH
ASDAAGMVTGTELFVDGGQTAGIAPSHFG
HCCCCCEEECCEEEEECCCCCCCCCCCCC
>Mature Secondary Structure 
TTTIETRLMDLTGRVAFVTGGASGIGRATAHALAAQGARVIVADINETGGWETADAIGT
CCCHHHHHHHHCCEEEEEECCCCCCHHHHHHHHHHCCCEEEEEECCCCCCCCCHHHHHH
AAGFVHLDVTEETAWCRALDYVISTEGRLDILANVAGIGLGGDFEDLALADWNRLMAVNA
HCCEEEEEECCCHHHHHHHHHHHCCCCCEEEEEEHHEECCCCCHHHHHHHCCCEEEEEEC
TGPFLGCKHAIRAMAGSGRPGAIINVGSIAATHAAPDLGGYCASKGALRMLSKSVALYCA
CCCCHHHHHHHHHHHCCCCCCEEEEECCEEECCCCCCCCCHHHCHHHHHHHHHHHEEEEE
HKGYPIRCNAVHPTYVDSEMLDPIAALYGSREAMVQAMARLVPVGRLAKPADVAAAVVYL
CCCCCEEECCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHH
ASDAAGMVTGTELFVDGGQTAGIAPSHFG
HCCCCCEEECCEEEEECCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]