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The map label for this gene is lytC [H]

Identifier: 119871516

GI number: 119871516

Start: 5735181

End: 5736377

Strand: Direct

Name: lytC [H]

Synonym: Mkms_5493

Alternate gene names: 119871516

Gene position: 5735181-5736377 (Clockwise)

Preceding gene: 119871515

Following gene: NA

Centisome position: 99.96

GC content: 67.59

Gene sequence:

>1197_bases
ATGTCGAGTCTGCGTCACGGTGATCGCGGAGCCGCGGTCACCGAGATCCGCGCAGCGCTCTCCGCTCTGGGCCTGCTGGA
CAGCCCCGACGACGACCTCACCACCGGAAGACATGTCGTCGCAGACCTGTTCGACGACCATCTCGACCAGGCGGTCCGCG
CCTTCCAGCAGCACCGCGGGCTCCTGGTCGACGGCATCGTCGGTGAGGCCACGTACCGGGCGCTGAAAGAGGCGTCCTAC
CGCCTCGGCGCACGTACGTTGATGCATCAGTTCGGCGCCCCGATGTACGGCGACGATGTCGCGACACTGCAGGCGCGCCT
GCAGGATCTCGGGTTCTACACTGGTCTGGTCGACGGGCACTTCGGGCTGCAGACCCATCACGGGCTCACCTCCTACCAAC
GCGAGTACGGGCTCTATCCCGACGGCATCTGCGGTCCGGAGACCCTGCGCTCGCTGTACTTCCTCGGGTCACGCGTGACC
GGCGGTTCGCCGCACGCGATCCGGGAGGAGGAGCTCGTCCGCCGCTCCGGTCCGCGACTGTCGGGCAAGCGGGTCATCAT
CGATCCGGGCCGCGGCGGCAGCGACCACGGCCTCATCATGAACGGGCCCCAGGGTCCGATCAGCGAAGCAGACATCCTGT
GGGACTTGGCAAGTCGCCTCGAGGGCCGGATGACCGCGATCGGGATGGACACGTTCCTGTCCCGCCCGGCCAACCGCAGC
CCCTCCGACGCCGAACGCGCCGCGACTGCCAACACCGTCGGCGCGGACCTGATGATCAGCCTGCGCTGCGCCGCACAGCC
CACCCCGGCCGCGAACGGCGTCGCGTCGTTCCACTTCGGCAACTCACACGGGTCGGTCTCCACCATCGGACGCAATCTCG
CCGACTTCATCCAGCGAGAGGTCGTCGCCCGCACCGGATTACGGGACTGCCGCACCCACGGCCGGACCTGGGATCTGCTG
CGTCTGACCCGGATGCCCACGGTGCAGGTCGATGTCGGCTACATCACCAACCCCCGTGACCGGGAGCTGTTGGTGTCCAA
CCACAATCGGGACGCGATCGCCGAAGGTATCCTCGCCGCGGTCAAGCGGCTCTATCTGCTCGGTAAGAACGACCGCCCCA
CAGGGACATTCACCTTCGCCGAACTGCTGGCGCACGAACTGTCCGTCGAACAGGCCGGCCGGCTCAGCTCGAACTGA

Upstream 100 bases:

>100_bases
GACCGGAACTTCTGAGACAATGCCTTTCGGGCCTGTCGTGCATATGTCGATGCCGCAGGGGTACTGACAGCCATAACGAG
GGCCTGCCGAAGGGGCGAGT

Downstream 100 bases:

>100_bases
CCGGTTCGGTCGCTAACAGCGGCCGCTGCCCGCCCCGACGGGCTGCTGCAGTTGGGCCGACTCCAGAAGCCGCTCCAGCG
CCGCTTCGACATCGGCCTTC

Product: peptidoglycan binding domain-containing protein

Products: NA

Alternate protein names: Cell wall hydrolase; Cell wall-associated polypeptide CWBP49; CWBP49; Major autolysin [H]

Number of amino acids: Translated: 398; Mature: 397

Protein sequence:

>398_residues
MSSLRHGDRGAAVTEIRAALSALGLLDSPDDDLTTGRHVVADLFDDHLDQAVRAFQQHRGLLVDGIVGEATYRALKEASY
RLGARTLMHQFGAPMYGDDVATLQARLQDLGFYTGLVDGHFGLQTHHGLTSYQREYGLYPDGICGPETLRSLYFLGSRVT
GGSPHAIREEELVRRSGPRLSGKRVIIDPGRGGSDHGLIMNGPQGPISEADILWDLASRLEGRMTAIGMDTFLSRPANRS
PSDAERAATANTVGADLMISLRCAAQPTPAANGVASFHFGNSHGSVSTIGRNLADFIQREVVARTGLRDCRTHGRTWDLL
RLTRMPTVQVDVGYITNPRDRELLVSNHNRDAIAEGILAAVKRLYLLGKNDRPTGTFTFAELLAHELSVEQAGRLSSN

Sequences:

>Translated_398_residues
MSSLRHGDRGAAVTEIRAALSALGLLDSPDDDLTTGRHVVADLFDDHLDQAVRAFQQHRGLLVDGIVGEATYRALKEASY
RLGARTLMHQFGAPMYGDDVATLQARLQDLGFYTGLVDGHFGLQTHHGLTSYQREYGLYPDGICGPETLRSLYFLGSRVT
GGSPHAIREEELVRRSGPRLSGKRVIIDPGRGGSDHGLIMNGPQGPISEADILWDLASRLEGRMTAIGMDTFLSRPANRS
PSDAERAATANTVGADLMISLRCAAQPTPAANGVASFHFGNSHGSVSTIGRNLADFIQREVVARTGLRDCRTHGRTWDLL
RLTRMPTVQVDVGYITNPRDRELLVSNHNRDAIAEGILAAVKRLYLLGKNDRPTGTFTFAELLAHELSVEQAGRLSSN
>Mature_397_residues
SSLRHGDRGAAVTEIRAALSALGLLDSPDDDLTTGRHVVADLFDDHLDQAVRAFQQHRGLLVDGIVGEATYRALKEASYR
LGARTLMHQFGAPMYGDDVATLQARLQDLGFYTGLVDGHFGLQTHHGLTSYQREYGLYPDGICGPETLRSLYFLGSRVTG
GSPHAIREEELVRRSGPRLSGKRVIIDPGRGGSDHGLIMNGPQGPISEADILWDLASRLEGRMTAIGMDTFLSRPANRSP
SDAERAATANTVGADLMISLRCAAQPTPAANGVASFHFGNSHGSVSTIGRNLADFIQREVVARTGLRDCRTHGRTWDLLR
LTRMPTVQVDVGYITNPRDRELLVSNHNRDAIAEGILAAVKRLYLLGKNDRPTGTFTFAELLAHELSVEQAGRLSSN

Specific function: Autolysins are involved in some important biological processes such as cell separation, cell-wall turnover, competence for genetic transformation, formation of the flagella - in particular of its basal body - and sporulation. Has a high affinity for teich

COG id: COG0860

COG function: function code M; N-acetylmuramoyl-L-alanine amidase

Gene ontology:

Cell location: Secreted, cell wall [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the N-acetylmuramoyl-L-alanine amidase 3 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007253
- InterPro:   IPR002508 [H]

Pfam domain/function: PF01520 Amidase_3; PF04122 CW_binding_2 [H]

EC number: =3.5.1.28 [H]

Molecular weight: Translated: 43244; Mature: 43113

Theoretical pI: Translated: 7.08; Mature: 7.08

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSLRHGDRGAAVTEIRAALSALGLLDSPDDDLTTGRHVVADLFDDHLDQAVRAFQQHRG
CCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCC
LLVDGIVGEATYRALKEASYRLGARTLMHQFGAPMYGDDVATLQARLQDLGFYTGLVDGH
EEEECHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCC
FGLQTHHGLTSYQREYGLYPDGICGPETLRSLYFLGSRVTGGSPHAIREEELVRRSGPRL
CCCCCCCCHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHCCCCC
SGKRVIIDPGRGGSDHGLIMNGPQGPISEADILWDLASRLEGRMTAIGMDTFLSRPANRS
CCCEEEEECCCCCCCCCEEEECCCCCCCHHHHHHHHHHHHCCCEEEEEHHHHHCCCCCCC
PSDAERAATANTVGADLMISLRCAAQPTPAANGVASFHFGNSHGSVSTIGRNLADFIQRE
CCHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHH
VVARTGLRDCRTHGRTWDLLRLTRMPTVQVDVGYITNPRDRELLVSNHNRDAIAEGILAA
HHHHCCHHHHHHCCCCCHHHHHHCCCEEEEEECCCCCCCCCEEEEECCCHHHHHHHHHHH
VKRLYLLGKNDRPTGTFTFAELLAHELSVEQAGRLSSN
HHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
SSLRHGDRGAAVTEIRAALSALGLLDSPDDDLTTGRHVVADLFDDHLDQAVRAFQQHRG
CCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCC
LLVDGIVGEATYRALKEASYRLGARTLMHQFGAPMYGDDVATLQARLQDLGFYTGLVDGH
EEEECHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCC
FGLQTHHGLTSYQREYGLYPDGICGPETLRSLYFLGSRVTGGSPHAIREEELVRRSGPRL
CCCCCCCCHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHCCCCC
SGKRVIIDPGRGGSDHGLIMNGPQGPISEADILWDLASRLEGRMTAIGMDTFLSRPANRS
CCCEEEEECCCCCCCCCEEEECCCCCCCHHHHHHHHHHHHCCCEEEEEHHHHHCCCCCCC
PSDAERAATANTVGADLMISLRCAAQPTPAANGVASFHFGNSHGSVSTIGRNLADFIQRE
CCHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHH
VVARTGLRDCRTHGRTWDLLRLTRMPTVQVDVGYITNPRDRELLVSNHNRDAIAEGILAA
HHHHCCHHHHHHCCCCCHHHHHHCCCEEEEEECCCCCCCCCEEEEECCCHHHHHHHHHHH
VKRLYLLGKNDRPTGTFTFAELLAHELSVEQAGRLSSN
HHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1357079; 1682302; 9384377 [H]