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The map label for this gene is muT4 [H]

Identifier: 119871510

GI number: 119871510

Start: 5725808

End: 5726620

Strand: Direct

Name: muT4 [H]

Synonym: Mkms_5487

Alternate gene names: 119871510

Gene position: 5725808-5726620 (Clockwise)

Preceding gene: 119871506

Following gene: 119871511

Centisome position: 99.8

GC content: 72.2

Gene sequence:

>813_bases
GTGTCGGAAGGCGAACAGCCCAAACCACGACGCCGCCGCGGGCGACGTCGCGGCCGACGCGCGGCCGGACCCCCGCAGGC
GGCGACCGACCGATCCACCGCCTCCGCCGAGCCCGCCAACGGCTCCGGCCCCGCGGATACCCCCGGGACCGGTACCCCCG
GAACAGGGGCCAAACCCACCGATCAGGCCCGCAAGGCCCGGCCCCGCCGCCCCCAGGAGCGGCTGCGCACCGTGCACGAG
ACCTCGGCGGGCGGTCTGGTCATCGACGGTATCGACGGACCGAAGGACAGTCAGGTGGCGGCTTTGATCGGCCGCATCGA
CCGCCGCGGCCGGATGCTGTGGTCACTGCCCAAGGGGCACATCGAGATGGGTGAGACGGCCGAGCAGACCGCGATCCGCG
AGGTCGCCGAGGAGACCGGCATCCGCGGTGACGTGCTCGCCGCGCTGGGCAGCATCGACTACTGGTTCGTCACCGAGGGG
CGCCGCGTCCACAAGACCGTGCACCATTACCTGATGCGATTCCTCGGCGGTGAACTGTCCGACGAGGACGTCGAGGTGAC
CGAGGTGGCCTGGGTGCCGCTCGAGGAACTGCCCAGCCGGCTGGCCTACGCCGACGAACGCCGACTGGCCGAGGTCGCCC
ACGAACTCATCGACAAACTGCACGCCGACGGTCCGGCGGCGCTCCCGCCGCTGCCGCGCTCGGCGCCGCGGCGACGCCCG
CAGACCCATTCGCACACCCGCAACCGTCGTCGTGACGAGTCCAGCCAAACCCCTCCCGGCCGGCGGACGAACGGATGCGG
ACAAGGGCAGTGA

Upstream 100 bases:

>100_bases
TGGGTCGTGCGGCACGTTCGTTGAGCCTAGAGGGTAACGGTCCGGCAGCGACCGGCGAGTGTGGCCGGAGCGAAACTGGG
TGGCAGCTACTATCGCTTGG

Downstream 100 bases:

>100_bases
GGACCGTGGCGGCGCCACGCATGACGACGGCGGTGCCGCGTCTGCTGGCCGCACTGGTCCTGTTGCTGCTGACCGCCATC
TCGACCGTCCTTCCGCATGC

Product: NUDIX hydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 270; Mature: 269

Protein sequence:

>270_residues
MSEGEQPKPRRRRGRRRGRRAAGPPQAATDRSTASAEPANGSGPADTPGTGTPGTGAKPTDQARKARPRRPQERLRTVHE
TSAGGLVIDGIDGPKDSQVAALIGRIDRRGRMLWSLPKGHIEMGETAEQTAIREVAEETGIRGDVLAALGSIDYWFVTEG
RRVHKTVHHYLMRFLGGELSDEDVEVTEVAWVPLEELPSRLAYADERRLAEVAHELIDKLHADGPAALPPLPRSAPRRRP
QTHSHTRNRRRDESSQTPPGRRTNGCGQGQ

Sequences:

>Translated_270_residues
MSEGEQPKPRRRRGRRRGRRAAGPPQAATDRSTASAEPANGSGPADTPGTGTPGTGAKPTDQARKARPRRPQERLRTVHE
TSAGGLVIDGIDGPKDSQVAALIGRIDRRGRMLWSLPKGHIEMGETAEQTAIREVAEETGIRGDVLAALGSIDYWFVTEG
RRVHKTVHHYLMRFLGGELSDEDVEVTEVAWVPLEELPSRLAYADERRLAEVAHELIDKLHADGPAALPPLPRSAPRRRP
QTHSHTRNRRRDESSQTPPGRRTNGCGQGQ
>Mature_269_residues
SEGEQPKPRRRRGRRRGRRAAGPPQAATDRSTASAEPANGSGPADTPGTGTPGTGAKPTDQARKARPRRPQERLRTVHET
SAGGLVIDGIDGPKDSQVAALIGRIDRRGRMLWSLPKGHIEMGETAEQTAIREVAEETGIRGDVLAALGSIDYWFVTEGR
RVHKTVHHYLMRFLGGELSDEDVEVTEVAWVPLEELPSRLAYADERRLAEVAHELIDKLHADGPAALPPLPRSAPRRRPQ
THSHTRNRRRDESSQTPPGRRTNGCGQGQ

Specific function: May be involved in the GO system responsible for removing an oxidatively damaged form of guanine (7,8-dihydro-8- oxoguanine, 8-oxo-dGTP) from DNA and the nucleotide pool. In vitro has dATPase rather than 8-oxo-dGTPase activity [H]

COG id: COG0494

COG function: function code LR; NTP pyrophosphohydrolases including oxidative damage repair enzymes

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 nudix hydrolase domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020476
- InterPro:   IPR020084
- InterPro:   IPR000086
- InterPro:   IPR015797 [H]

Pfam domain/function: PF00293 NUDIX [H]

EC number: NA

Molecular weight: Translated: 29608; Mature: 29477

Theoretical pI: Translated: 10.69; Mature: 10.69

Prosite motif: PS00893 NUDIX

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEGEQPKPRRRRGRRRGRRAAGPPQAATDRSTASAEPANGSGPADTPGTGTPGTGAKPT
CCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
DQARKARPRRPQERLRTVHETSAGGLVIDGIDGPKDSQVAALIGRIDRRGRMLWSLPKGH
HHHHHCCCCCHHHHHHHHHHCCCCCEEEECCCCCCHHHHHHHHHHHHHCCCEEEECCCCC
IEMGETAEQTAIREVAEETGIRGDVLAALGSIDYWFVTEGRRVHKTVHHYLMRFLGGELS
CCCCCHHHHHHHHHHHHHHCCCHHHHHHHHCCCEEEECCCHHHHHHHHHHHHHHHCCCCC
DEDVEVTEVAWVPLEELPSRLAYADERRLAEVAHELIDKLHADGPAALPPLPRSAPRRRP
CCCCEEHHEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCC
QTHSHTRNRRRDESSQTPPGRRTNGCGQGQ
CCHHHHHHHHHCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
SEGEQPKPRRRRGRRRGRRAAGPPQAATDRSTASAEPANGSGPADTPGTGTPGTGAKPT
CCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
DQARKARPRRPQERLRTVHETSAGGLVIDGIDGPKDSQVAALIGRIDRRGRMLWSLPKGH
HHHHHCCCCCHHHHHHHHHHCCCCCEEEECCCCCCHHHHHHHHHHHHHCCCEEEECCCCC
IEMGETAEQTAIREVAEETGIRGDVLAALGSIDYWFVTEGRRVHKTVHHYLMRFLGGELS
CCCCCHHHHHHHHHHHHHHCCCHHHHHHHHCCCEEEECCCHHHHHHHHHHHHHHHCCCCC
DEDVEVTEVAWVPLEELPSRLAYADERRLAEVAHELIDKLHADGPAALPPLPRSAPRRRP
CCCCEEHHEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCC
QTHSHTRNRRRDESSQTPPGRRTNGCGQGQ
CCHHHHHHHHHCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]