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The map label for this gene is ybbO [C]

Identifier: 119871499

GI number: 119871499

Start: 5713610

End: 5714278

Strand: Direct

Name: ybbO [C]

Synonym: Mkms_5476

Alternate gene names: 119871499

Gene position: 5713610-5714278 (Clockwise)

Preceding gene: 119871497

Following gene: 119871502

Centisome position: 99.59

GC content: 70.55

Gene sequence:

>669_bases
ATGCCGACCGCGATGATCACAGGCGCCAGCCGCGGCCTCGGGGCGGCCATCGCCACCGCGCTGGCGCCCACCCACACGTT
GTTCCTCGCCGGCCGGCCGTCCGCGCAACTCGACGAGGTCGCGCAGCGCCTCGGCGCCACCACCTGGGAGATCGACTTCG
ACGACGTCGACACGATCCCGGCCGCCGTCGAGCCGATCGTCGAACTCGACGTGCTGATCCACAATGCCGGTGTCGCCTAT
CCGGCGCGCGTCGCCGAATCCACCGTCGACGAGTGGCGGGCCACGATGAACGTCAACGTGATCGGCGCCGTCGCGCTCAC
GCTGGCGTTGTTGCCTGCGCTGCGGGCGGCCCCGGACGGGCAGGTGGTGTTCATCAACTCGGGGTCGGGGATCAACGCCT
CCCCCGGCCTGGCGTCGTATTCGGCGAGCAAGTTCGCGCTGCGCGCGTTCGCCGACTCACTGCGCAACGACGAGGCCGGT
CTGCGGGTCACCTCCGTGCATCCGGGCCGGATCGCGACGGAGATGCAGCAGGACCTTCGGGCCTACGAGGGGCGGGACTA
CAACCCGGCCGACTTCCTCAGCGCGGAGACCGTCGCCAAGGTGACGGCCGACGCGGTCAACGCTCCCGCCGATGCGCACA
TCCACGAGGTGATCGTCCGCCCCCGATAG

Upstream 100 bases:

>100_bases
CGCGGGCCGCGAGTTGCGTGGGCGCGAAGCTGGGGTCGTGTGGCATCAGTCCAATCATGCGACGGCAATGCGTTTCGCGC
AGGTCGGTAGGGTTGGCGAC

Downstream 100 bases:

>100_bases
TTGCGATTTCGGCGTGCTGGGTCGCGCTGAGCGCGACTGCTCACGCCGAAATCGCGGTGCGCAGGACCGCGATCACCCGA
TCGGGATACTCGGTGAGGTC

Product: short chain dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 222; Mature: 221

Protein sequence:

>222_residues
MPTAMITGASRGLGAAIATALAPTHTLFLAGRPSAQLDEVAQRLGATTWEIDFDDVDTIPAAVEPIVELDVLIHNAGVAY
PARVAESTVDEWRATMNVNVIGAVALTLALLPALRAAPDGQVVFINSGSGINASPGLASYSASKFALRAFADSLRNDEAG
LRVTSVHPGRIATEMQQDLRAYEGRDYNPADFLSAETVAKVTADAVNAPADAHIHEVIVRPR

Sequences:

>Translated_222_residues
MPTAMITGASRGLGAAIATALAPTHTLFLAGRPSAQLDEVAQRLGATTWEIDFDDVDTIPAAVEPIVELDVLIHNAGVAY
PARVAESTVDEWRATMNVNVIGAVALTLALLPALRAAPDGQVVFINSGSGINASPGLASYSASKFALRAFADSLRNDEAG
LRVTSVHPGRIATEMQQDLRAYEGRDYNPADFLSAETVAKVTADAVNAPADAHIHEVIVRPR
>Mature_221_residues
PTAMITGASRGLGAAIATALAPTHTLFLAGRPSAQLDEVAQRLGATTWEIDFDDVDTIPAAVEPIVELDVLIHNAGVAYP
ARVAESTVDEWRATMNVNVIGAVALTLALLPALRAAPDGQVVFINSGSGINASPGLASYSASKFALRAFADSLRNDEAGL
RVTSVHPGRIATEMQQDLRAYEGRDYNPADFLSAETVAKVTADAVNAPADAHIHEVIVRPR

Specific function: Unknown

COG id: COG1028

COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI20149619, Length=210, Percent_Identity=33.3333333333333, Blast_Score=96, Evalue=3e-20,
Organism=Homo sapiens, GI7706318, Length=190, Percent_Identity=27.8947368421053, Blast_Score=81, Evalue=8e-16,
Organism=Homo sapiens, GI109715829, Length=243, Percent_Identity=27.1604938271605, Blast_Score=76, Evalue=2e-14,
Organism=Homo sapiens, GI31543615, Length=191, Percent_Identity=28.7958115183246, Blast_Score=69, Evalue=4e-12,
Organism=Homo sapiens, GI226371731, Length=187, Percent_Identity=31.0160427807487, Blast_Score=68, Evalue=7e-12,
Organism=Homo sapiens, GI22507405, Length=184, Percent_Identity=32.0652173913043, Blast_Score=67, Evalue=8e-12,
Organism=Escherichia coli, GI1786701, Length=184, Percent_Identity=28.804347826087, Blast_Score=77, Evalue=9e-16,
Organism=Escherichia coli, GI1787820, Length=235, Percent_Identity=26.8085106382979, Blast_Score=74, Evalue=8e-15,
Organism=Escherichia coli, GI87082100, Length=201, Percent_Identity=28.8557213930348, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1787335, Length=187, Percent_Identity=29.9465240641711, Blast_Score=72, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI71997402, Length=233, Percent_Identity=31.7596566523605, Blast_Score=87, Evalue=5e-18,
Organism=Caenorhabditis elegans, GI17570069, Length=217, Percent_Identity=32.258064516129, Blast_Score=86, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI71994600, Length=194, Percent_Identity=34.020618556701, Blast_Score=74, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI17508895, Length=186, Percent_Identity=29.5698924731183, Blast_Score=74, Evalue=9e-14,
Organism=Caenorhabditis elegans, GI71994604, Length=194, Percent_Identity=32.4742268041237, Blast_Score=73, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17559104, Length=190, Percent_Identity=30, Blast_Score=72, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17560676, Length=193, Percent_Identity=30.0518134715026, Blast_Score=66, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6322227, Length=194, Percent_Identity=30.4123711340206, Blast_Score=84, Evalue=2e-17,
Organism=Saccharomyces cerevisiae, GI6323882, Length=243, Percent_Identity=28.3950617283951, Blast_Score=80, Evalue=2e-16,
Organism=Saccharomyces cerevisiae, GI6322226, Length=186, Percent_Identity=30.6451612903226, Blast_Score=77, Evalue=2e-15,
Organism=Drosophila melanogaster, GI21358495, Length=212, Percent_Identity=36.7924528301887, Blast_Score=107, Evalue=5e-24,
Organism=Drosophila melanogaster, GI23397609, Length=192, Percent_Identity=34.8958333333333, Blast_Score=90, Evalue=1e-18,
Organism=Drosophila melanogaster, GI116007236, Length=241, Percent_Identity=28.6307053941909, Blast_Score=82, Evalue=3e-16,
Organism=Drosophila melanogaster, GI28571526, Length=188, Percent_Identity=32.4468085106383, Blast_Score=79, Evalue=2e-15,
Organism=Drosophila melanogaster, GI21357041, Length=195, Percent_Identity=32.3076923076923, Blast_Score=79, Evalue=3e-15,
Organism=Drosophila melanogaster, GI24651139, Length=191, Percent_Identity=31.413612565445, Blast_Score=74, Evalue=5e-14,
Organism=Drosophila melanogaster, GI24641232, Length=242, Percent_Identity=29.3388429752066, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI116007234, Length=243, Percent_Identity=29.2181069958848, Blast_Score=72, Evalue=3e-13,
Organism=Drosophila melanogaster, GI28571387, Length=240, Percent_Identity=27.9166666666667, Blast_Score=70, Evalue=9e-13,
Organism=Drosophila melanogaster, GI24641388, Length=243, Percent_Identity=29.2181069958848, Blast_Score=68, Evalue=6e-12,
Organism=Drosophila melanogaster, GI24644339, Length=225, Percent_Identity=28.4444444444444, Blast_Score=67, Evalue=8e-12,
Organism=Drosophila melanogaster, GI24640547, Length=206, Percent_Identity=31.0679611650485, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24663911, Length=245, Percent_Identity=26.9387755102041, Blast_Score=66, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24640442, Length=197, Percent_Identity=26.9035532994924, Blast_Score=65, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24648693, Length=241, Percent_Identity=29.045643153527, Blast_Score=65, Evalue=3e-11,
Organism=Drosophila melanogaster, GI21355889, Length=241, Percent_Identity=29.045643153527, Blast_Score=65, Evalue=3e-11,
Organism=Drosophila melanogaster, GI281364494, Length=242, Percent_Identity=27.2727272727273, Blast_Score=65, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 23307; Mature: 23176

Theoretical pI: Translated: 4.62; Mature: 4.62

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPTAMITGASRGLGAAIATALAPTHTLFLAGRPSAQLDEVAQRLGATTWEIDFDDVDTIP
CCCCEECCCCCCHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHCCEEEEEECCCCCCCH
AAVEPIVELDVLIHNAGVAYPARVAESTVDEWRATMNVNVIGAVALTLALLPALRAAPDG
HHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCC
QVVFINSGSGINASPGLASYSASKFALRAFADSLRNDEAGLRVTSVHPGRIATEMQQDLR
CEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCEEEEEECCCHHHHHHHHHHH
AYEGRDYNPADFLSAETVAKVTADAVNAPADAHIHEVIVRPR
HHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHEEECCC
>Mature Secondary Structure 
PTAMITGASRGLGAAIATALAPTHTLFLAGRPSAQLDEVAQRLGATTWEIDFDDVDTIP
CCCEECCCCCCHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHCCEEEEEECCCCCCCH
AAVEPIVELDVLIHNAGVAYPARVAESTVDEWRATMNVNVIGAVALTLALLPALRAAPDG
HHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCC
QVVFINSGSGINASPGLASYSASKFALRAFADSLRNDEAGLRVTSVHPGRIATEMQQDLR
CEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCEEEEEECCCHHHHHHHHHHH
AYEGRDYNPADFLSAETVAKVTADAVNAPADAHIHEVIVRPR
HHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12950922 [H]