Click here to switch to the map view.

The map label for this gene is idsA [H]

Identifier: 119871189

GI number: 119871189

Start: 5410466

End: 5411590

Strand: Direct

Name: idsA [H]

Synonym: Mkms_5162

Alternate gene names: 119871189

Gene position: 5410466-5411590 (Clockwise)

Preceding gene: 119871186

Following gene: 119871190

Centisome position: 94.3

GC content: 70.67

Gene sequence:

>1125_bases
GTGAGCGGTGTCGACGATCGGCTGCTCGCCGCAGCTTTGCGGCCAGCCCCAGCCCGGCTCACGGCCGACTCCTTCGACAC
CTGGCGCAGGGATGTACGCCGCGCGGCGATCGATGCGGTGACCGAGTTCGTCACCGACCGGTGCGCCGACGACCTGCGGC
TCACCGGTGTCGACGTCACCCTCGACGTGCTCTCCGACTTCGTCAGCGACGGTAAGTGCCTGCGCTCGACGTTCGCCTAC
CTCGGTTGGCTGGCCGGTGCCGCACCCGACGACGCCGCCCTGCGCGCCGCGGCGAGTTTCGACCTGCTGCACGTGTTCGC
ACTGCTGCAGGACGACGTGATGGACGACTCACCGCTGCGCCGTGGCCGTCCGGCGGCGCATGTGCGCTTCGCGCAGTGGC
ACCGGGACAACGGACTCAACGGATCCGCGGAGCGGTTCGGCGCCTCGGCGGCGGTGCTGCTCGGCGACCTCTGCCTGGTG
TGGGCGGGGCAGATGATGCGCGAGAGCGGTCTGGGTGACCGGGCACTGGCCCGGGCGTGGCCCCGGTATGACGCGATGCG
CACGGAATTGGCGGTGGGCCAGTTCGCCGATCTGGTCAATGATGCGGGCGGACGGCCGACACTGGAGGACGTGCTCGACG
TCGCACGCCGCAAATCCGGGAACTACACGGTGCGCCGCCCCCTGGAGATCGGCGGTGCACTGGCCGGCTGCCCGGACGCG
ACGCTGGGCTTGCTCGGCCGCTACGGCGCGGCCGTCGGTGAGGCGTTCCAGCTGCGCGACGACCTCCTCGGCATCTTCGG
TGCCCCGACGGTGACCGGCAAACCCGCAGGCGGCGACCTGTCCGAACACAAGGCCACCAGCGTGGTGGTCGCGGCGCACC
GGCTGGCCGAACCGTCGGTGCGCAACCAACTCACCGAGTTGATGTCGCGACGCGACCTCGACGCGGGTGACATCACCCGC
TGGCAGCACCTCATCGCCGCGACCGGCGCCGTGCAGTGGATCGAGCAGCTGATCGACCGGCGGCTCTCCCATGCGCTGGA
GCGCATCCACACCAGCCCACTCGACGACACCGTCAGAACCGCACTGGTCAACATGGCCGCCGTATGCACCCGGCGGGCAG
CGTGA

Upstream 100 bases:

>100_bases
AATCGTGACATCGGATCCCGATTGGTTTCCACGATCACGGGTACGGACAACTAGAACCCTAGTTTGGTGATCACAGCAGG
GTGACGGCGGAAGGCTTCGG

Downstream 100 bases:

>100_bases
CCGGCAAACAGTCAGGAGAATCGAACTGATGCGCACCGTCGGGGGGCGAACAGACCGCGTGGTGGTCGTCGGCGCCGGAT
TGTCCGGCCTGTCGGCCGCA

Product: polyprenyl synthetase

Products: NA

Alternate protein names: (2E,6E)-farnesyl diphosphate synthase; Dimethylallyltranstransferase; Farnesyl diphosphate synthase; Farnesyl pyrophosphate synthase; FPP synthase; Geranyltranstransferase [H]

Number of amino acids: Translated: 374; Mature: 373

Protein sequence:

>374_residues
MSGVDDRLLAAALRPAPARLTADSFDTWRRDVRRAAIDAVTEFVTDRCADDLRLTGVDVTLDVLSDFVSDGKCLRSTFAY
LGWLAGAAPDDAALRAAASFDLLHVFALLQDDVMDDSPLRRGRPAAHVRFAQWHRDNGLNGSAERFGASAAVLLGDLCLV
WAGQMMRESGLGDRALARAWPRYDAMRTELAVGQFADLVNDAGGRPTLEDVLDVARRKSGNYTVRRPLEIGGALAGCPDA
TLGLLGRYGAAVGEAFQLRDDLLGIFGAPTVTGKPAGGDLSEHKATSVVVAAHRLAEPSVRNQLTELMSRRDLDAGDITR
WQHLIAATGAVQWIEQLIDRRLSHALERIHTSPLDDTVRTALVNMAAVCTRRAA

Sequences:

>Translated_374_residues
MSGVDDRLLAAALRPAPARLTADSFDTWRRDVRRAAIDAVTEFVTDRCADDLRLTGVDVTLDVLSDFVSDGKCLRSTFAY
LGWLAGAAPDDAALRAAASFDLLHVFALLQDDVMDDSPLRRGRPAAHVRFAQWHRDNGLNGSAERFGASAAVLLGDLCLV
WAGQMMRESGLGDRALARAWPRYDAMRTELAVGQFADLVNDAGGRPTLEDVLDVARRKSGNYTVRRPLEIGGALAGCPDA
TLGLLGRYGAAVGEAFQLRDDLLGIFGAPTVTGKPAGGDLSEHKATSVVVAAHRLAEPSVRNQLTELMSRRDLDAGDITR
WQHLIAATGAVQWIEQLIDRRLSHALERIHTSPLDDTVRTALVNMAAVCTRRAA
>Mature_373_residues
SGVDDRLLAAALRPAPARLTADSFDTWRRDVRRAAIDAVTEFVTDRCADDLRLTGVDVTLDVLSDFVSDGKCLRSTFAYL
GWLAGAAPDDAALRAAASFDLLHVFALLQDDVMDDSPLRRGRPAAHVRFAQWHRDNGLNGSAERFGASAAVLLGDLCLVW
AGQMMRESGLGDRALARAWPRYDAMRTELAVGQFADLVNDAGGRPTLEDVLDVARRKSGNYTVRRPLEIGGALAGCPDAT
LGLLGRYGAAVGEAFQLRDDLLGIFGAPTVTGKPAGGDLSEHKATSVVVAAHRLAEPSVRNQLTELMSRRDLDAGDITRW
QHLIAATGAVQWIEQLIDRRLSHALERIHTSPLDDTVRTALVNMAAVCTRRAA

Specific function: Supplies Octaprenyl Diphosphate, The Precursor For The Side Chain Of The Isoprenoid Quinones Ubiquinone And Menaquinone. [C]

COG id: COG0142

COG function: function code H; Geranylgeranyl pyrophosphate synthase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FPP/GGPP synthase family [H]

Homologues:

Organism=Escherichia coli, GI1789578, Length=310, Percent_Identity=28.7096774193548, Blast_Score=83, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI17508563, Length=203, Percent_Identity=28.0788177339901, Blast_Score=72, Evalue=6e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000092
- InterPro:   IPR017446
- InterPro:   IPR008949 [H]

Pfam domain/function: PF00348 polyprenyl_synt [H]

EC number: =2.5.1.1; =2.5.1.10 [H]

Molecular weight: Translated: 40402; Mature: 40271

Theoretical pI: Translated: 6.11; Mature: 6.11

Prosite motif: PS00723 POLYPRENYL_SYNTHET_1 ; PS00444 POLYPRENYL_SYNTHET_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSGVDDRLLAAALRPAPARLTADSFDTWRRDVRRAAIDAVTEFVTDRCADDLRLTGVDVT
CCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCHHH
LDVLSDFVSDGKCLRSTFAYLGWLAGAAPDDAALRAAASFDLLHVFALLQDDVMDDSPLR
HHHHHHHHHCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
RGRPAAHVRFAQWHRDNGLNGSAERFGASAAVLLGDLCLVWAGQMMRESGLGDRALARAW
CCCCHHHHHHHHHHCCCCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
PRYDAMRTELAVGQFADLVNDAGGRPTLEDVLDVARRKSGNYTVRRPLEIGGALAGCPDA
HHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCEEECHHHHCCCCCCCCHH
TLGLLGRYGAAVGEAFQLRDDLLGIFGAPTVTGKPAGGDLSEHKATSVVVAAHRLAEPSV
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCHH
RNQLTELMSRRDLDAGDITRWQHLIAATGAVQWIEQLIDRRLSHALERIHTSPLDDTVRT
HHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
ALVNMAAVCTRRAA
HHHHHHHHHHHCCC
>Mature Secondary Structure 
SGVDDRLLAAALRPAPARLTADSFDTWRRDVRRAAIDAVTEFVTDRCADDLRLTGVDVT
CCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCHHH
LDVLSDFVSDGKCLRSTFAYLGWLAGAAPDDAALRAAASFDLLHVFALLQDDVMDDSPLR
HHHHHHHHHCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
RGRPAAHVRFAQWHRDNGLNGSAERFGASAAVLLGDLCLVWAGQMMRESGLGDRALARAW
CCCCHHHHHHHHHHCCCCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
PRYDAMRTELAVGQFADLVNDAGGRPTLEDVLDVARRKSGNYTVRRPLEIGGALAGCPDA
HHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCEEECHHHHCCCCCCCCHH
TLGLLGRYGAAVGEAFQLRDDLLGIFGAPTVTGKPAGGDLSEHKATSVVVAAHRLAEPSV
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCHH
RNQLTELMSRRDLDAGDITRWQHLIAATGAVQWIEQLIDRRLSHALERIHTSPLDDTVRT
HHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
ALVNMAAVCTRRAA
HHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]