| Definition | Mycobacterium sp. KMS chromosome, complete genome. |
|---|---|
| Accession | NC_008705 |
| Length | 5,737,227 |
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The map label for this gene is fabG [H]
Identifier: 119871086
GI number: 119871086
Start: 5297858
End: 5298601
Strand: Direct
Name: fabG [H]
Synonym: Mkms_5059
Alternate gene names: 119871086
Gene position: 5297858-5298601 (Clockwise)
Preceding gene: 119871083
Following gene: 119871090
Centisome position: 92.34
GC content: 68.68
Gene sequence:
>744_bases ATGTTCGACCTGACCGACCGGGTGGTGCTGGTCACCGGCGGTAGCCGGGGGCTGGGCCGCGAGATCGCCTTCGGAGCCGC GCGCTGCGGGGCCGATGTGGTGATCGCCAGCCGGTCGCTCGAGACGTGCGAGGCGACCGCCGCCGAGATCGCCGAGGCGA CGGGCCGGACCGCCATGCCCTACGAGGTCCACGTGGGACGGTGGGATCAGCTCGACGGTCTGGTTTCCGCGGTGTACGAG CGGTTCGGCAAGCTCGACGTGCTGGTCAACAACGCCGGTATGTCACCGCTGTACGAGTCGCTGACGTCGGTGACCGAGAA GCTGTTCGACGCGGTGTTCAACCTGAACGTCAAGGGACCGTTCCGGTTGGCGGCGCTGATCGGTGAGCGGATGGTGGCCG ACGGCGGCGGGACGATCGTCAACGTCAGCTCCAGCGGATCGATCCGGCCCGATCCGCACATGCTGCCCTACGCCGCCGCC AAGGCCGGCCTCAACGCCATGACCGAGGGGCTGGCGCAGGCCTACGGCCCGACGGTGCGCGTCAACACGCTGATGGCCGG GCCGTTCCTCACCGATGTCAGCAAGGCGTGGGACTTCTCCGGTACCGAGAATCCGTTCGGTCACATGGCGCTGAAGCGGG CCGGGGATCCGGCCGAGATCGTCGGCGCCGCACTGTTTCTCATGTCGAATGCGTCGAGCTTCACCACCGGCGCCATCCTG CGCGCCGACGGCGGCATCCCCTGA
Upstream 100 bases:
>100_bases GTCGGAGCCCTGCCCGGGTTCACTGCGCAAGGGCAGCGCATGTCGGATGAGAAGCAGTTGCACCGTGCCACCATATTGGC CCATGGGATACGCCGACGAA
Downstream 100 bases:
>100_bases CGCCGTCCGCGACGGGTCGCCGAGGCTACGGCATGACGATGTCGAAAGCGGGGTCCGGGCGGTCGAGCACCCCCACGATG TTCGCCAGCGCCGCCTCGTC
Product: short-chain dehydrogenase/reductase SDR
Products: NA
Alternate protein names: 3-ketoacyl-acyl carrier protein reductase [H]
Number of amino acids: Translated: 247; Mature: 247
Protein sequence:
>247_residues MFDLTDRVVLVTGGSRGLGREIAFGAARCGADVVIASRSLETCEATAAEIAEATGRTAMPYEVHVGRWDQLDGLVSAVYE RFGKLDVLVNNAGMSPLYESLTSVTEKLFDAVFNLNVKGPFRLAALIGERMVADGGGTIVNVSSSGSIRPDPHMLPYAAA KAGLNAMTEGLAQAYGPTVRVNTLMAGPFLTDVSKAWDFSGTENPFGHMALKRAGDPAEIVGAALFLMSNASSFTTGAIL RADGGIP
Sequences:
>Translated_247_residues MFDLTDRVVLVTGGSRGLGREIAFGAARCGADVVIASRSLETCEATAAEIAEATGRTAMPYEVHVGRWDQLDGLVSAVYE RFGKLDVLVNNAGMSPLYESLTSVTEKLFDAVFNLNVKGPFRLAALIGERMVADGGGTIVNVSSSGSIRPDPHMLPYAAA KAGLNAMTEGLAQAYGPTVRVNTLMAGPFLTDVSKAWDFSGTENPFGHMALKRAGDPAEIVGAALFLMSNASSFTTGAIL RADGGIP >Mature_247_residues MFDLTDRVVLVTGGSRGLGREIAFGAARCGADVVIASRSLETCEATAAEIAEATGRTAMPYEVHVGRWDQLDGLVSAVYE RFGKLDVLVNNAGMSPLYESLTSVTEKLFDAVFNLNVKGPFRLAALIGERMVADGGGTIVNVSSSGSIRPDPHMLPYAAA KAGLNAMTEGLAQAYGPTVRVNTLMAGPFLTDVSKAWDFSGTENPFGHMALKRAGDPAEIVGAALFLMSNASSFTTGAIL RADGGIP
Specific function: Catalyzes A Reversible Reduction Of 5-Ketoglutanate To Form D-Gluconate. Dependent On Nadp, Almost Inactive With NAD. [C]
COG id: NA
COG function: NA
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Unknown [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]
Homologues:
Organism=Homo sapiens, GI32483357, Length=247, Percent_Identity=32.3886639676113, Blast_Score=125, Evalue=4e-29, Organism=Homo sapiens, GI10190704, Length=256, Percent_Identity=33.203125, Blast_Score=116, Evalue=2e-26, Organism=Homo sapiens, GI19923817, Length=258, Percent_Identity=30.6201550387597, Blast_Score=108, Evalue=5e-24, Organism=Homo sapiens, GI5031737, Length=239, Percent_Identity=32.2175732217573, Blast_Score=104, Evalue=6e-23, Organism=Homo sapiens, GI126723191, Length=182, Percent_Identity=33.5164835164835, Blast_Score=99, Evalue=3e-21, Organism=Homo sapiens, GI7705925, Length=246, Percent_Identity=30.4878048780488, Blast_Score=94, Evalue=9e-20, Organism=Homo sapiens, GI33667109, Length=193, Percent_Identity=33.160621761658, Blast_Score=90, Evalue=2e-18, Organism=Homo sapiens, GI126723750, Length=250, Percent_Identity=27.2, Blast_Score=89, Evalue=5e-18, Organism=Homo sapiens, GI40254992, Length=243, Percent_Identity=27.9835390946502, Blast_Score=86, Evalue=4e-17, Organism=Homo sapiens, GI40254986, Length=184, Percent_Identity=31.5217391304348, Blast_Score=85, Evalue=5e-17, Organism=Homo sapiens, GI4503301, Length=224, Percent_Identity=28.5714285714286, Blast_Score=78, Evalue=6e-15, Organism=Homo sapiens, GI4557649, Length=170, Percent_Identity=29.4117647058824, Blast_Score=77, Evalue=2e-14, Organism=Homo sapiens, GI59889578, Length=191, Percent_Identity=33.5078534031414, Blast_Score=77, Evalue=2e-14, Organism=Homo sapiens, GI7706318, Length=198, Percent_Identity=28.7878787878788, Blast_Score=75, Evalue=8e-14, Organism=Homo sapiens, GI302344755, Length=103, Percent_Identity=36.8932038834951, Blast_Score=72, Evalue=7e-13, Organism=Homo sapiens, GI209862901, Length=179, Percent_Identity=30.7262569832402, Blast_Score=70, Evalue=1e-12, Organism=Homo sapiens, GI19923983, Length=179, Percent_Identity=30.7262569832402, Blast_Score=70, Evalue=1e-12, Organism=Homo sapiens, GI4758504, Length=256, Percent_Identity=28.515625, Blast_Score=66, Evalue=3e-11, Organism=Escherichia coli, GI1790717, Length=249, Percent_Identity=30.5220883534137, Blast_Score=110, Evalue=1e-25, Organism=Escherichia coli, GI1789378, Length=249, Percent_Identity=32.9317269076305, Blast_Score=104, Evalue=6e-24, Organism=Escherichia coli, GI87082160, Length=248, Percent_Identity=29.8387096774194, Blast_Score=101, Evalue=4e-23, Organism=Escherichia coli, GI1789208, Length=249, Percent_Identity=29.718875502008, Blast_Score=100, Evalue=9e-23, Organism=Escherichia coli, GI1787905, Length=247, Percent_Identity=30.7692307692308, Blast_Score=96, Evalue=2e-21, Organism=Escherichia coli, GI2367365, Length=244, Percent_Identity=32.7868852459016, Blast_Score=96, Evalue=3e-21, Organism=Escherichia coli, GI87082100, Length=255, Percent_Identity=30.1960784313725, Blast_Score=88, Evalue=6e-19, Organism=Escherichia coli, GI1787335, Length=246, Percent_Identity=27.6422764227642, Blast_Score=86, Evalue=2e-18, Organism=Escherichia coli, GI1787526, Length=244, Percent_Identity=29.0983606557377, Blast_Score=85, Evalue=4e-18, Organism=Escherichia coli, GI2367175, Length=245, Percent_Identity=28.5714285714286, Blast_Score=84, Evalue=7e-18, Organism=Escherichia coli, GI1788459, Length=241, Percent_Identity=27.8008298755187, Blast_Score=83, Evalue=2e-17, Organism=Caenorhabditis elegans, GI17560676, Length=250, Percent_Identity=35.6, Blast_Score=125, Evalue=2e-29, Organism=Caenorhabditis elegans, GI115534694, Length=255, Percent_Identity=34.9019607843137, Blast_Score=124, Evalue=6e-29, Organism=Caenorhabditis elegans, GI17561402, Length=249, Percent_Identity=30.1204819277108, Blast_Score=109, Evalue=1e-24, Organism=Caenorhabditis elegans, GI17536651, Length=259, Percent_Identity=30.5019305019305, Blast_Score=102, Evalue=1e-22, Organism=Caenorhabditis elegans, GI17536025, Length=257, Percent_Identity=30.3501945525292, Blast_Score=100, Evalue=5e-22, Organism=Caenorhabditis elegans, GI71994604, Length=247, Percent_Identity=31.5789473684211, Blast_Score=99, Evalue=3e-21, Organism=Caenorhabditis elegans, GI17562910, Length=269, Percent_Identity=30.8550185873606, Blast_Score=90, Evalue=1e-18, Organism=Caenorhabditis elegans, GI71994600, Length=254, Percent_Identity=29.5275590551181, Blast_Score=88, Evalue=5e-18, Organism=Caenorhabditis elegans, GI17562904, Length=261, Percent_Identity=30.2681992337165, Blast_Score=86, Evalue=2e-17, Organism=Caenorhabditis elegans, GI17561272, Length=238, Percent_Identity=28.5714285714286, Blast_Score=84, Evalue=6e-17, Organism=Caenorhabditis elegans, GI193204405, Length=273, Percent_Identity=31.5018315018315, Blast_Score=84, Evalue=6e-17, Organism=Caenorhabditis elegans, GI17551412, Length=267, Percent_Identity=30.3370786516854, Blast_Score=84, Evalue=6e-17, Organism=Caenorhabditis elegans, GI17562906, Length=269, Percent_Identity=30.8550185873606, Blast_Score=84, Evalue=7e-17, Organism=Caenorhabditis elegans, GI17562990, Length=274, Percent_Identity=31.7518248175182, Blast_Score=84, Evalue=8e-17, Organism=Caenorhabditis elegans, GI17560150, Length=271, Percent_Identity=30.6273062730627, Blast_Score=82, Evalue=3e-16, Organism=Caenorhabditis elegans, GI17531453, Length=264, Percent_Identity=30.3030303030303, Blast_Score=81, Evalue=4e-16, Organism=Caenorhabditis elegans, GI17555706, Length=245, Percent_Identity=28.9795918367347, Blast_Score=81, Evalue=5e-16, Organism=Caenorhabditis elegans, GI25147288, Length=245, Percent_Identity=29.3877551020408, Blast_Score=79, Evalue=2e-15, Organism=Caenorhabditis elegans, GI17559104, Length=262, Percent_Identity=29.7709923664122, Blast_Score=77, Evalue=1e-14, Organism=Caenorhabditis elegans, GI17562908, Length=263, Percent_Identity=31.1787072243346, Blast_Score=76, Evalue=1e-14, Organism=Caenorhabditis elegans, GI17560332, Length=269, Percent_Identity=30.8550185873606, Blast_Score=75, Evalue=3e-14, Organism=Caenorhabditis elegans, GI72000259, Length=271, Percent_Identity=29.520295202952, Blast_Score=72, Evalue=2e-13, Organism=Caenorhabditis elegans, GI17563726, Length=259, Percent_Identity=28.957528957529, Blast_Score=72, Evalue=2e-13, Organism=Caenorhabditis elegans, GI71982365, Length=188, Percent_Identity=29.7872340425532, Blast_Score=71, Evalue=7e-13, Organism=Caenorhabditis elegans, GI17565030, Length=266, Percent_Identity=28.9473684210526, Blast_Score=69, Evalue=2e-12, Organism=Caenorhabditis elegans, GI17568967, Length=200, Percent_Identity=30.5, Blast_Score=68, Evalue=5e-12, Organism=Caenorhabditis elegans, GI17538480, Length=267, Percent_Identity=27.7153558052434, Blast_Score=68, Evalue=5e-12, Organism=Caenorhabditis elegans, GI17538486, Length=273, Percent_Identity=27.1062271062271, Blast_Score=67, Evalue=9e-12, Organism=Caenorhabditis elegans, GI71997099, Length=251, Percent_Identity=29.8804780876494, Blast_Score=66, Evalue=2e-11, Organism=Caenorhabditis elegans, GI17544670, Length=189, Percent_Identity=31.7460317460317, Blast_Score=66, Evalue=2e-11, Organism=Caenorhabditis elegans, GI17555612, Length=186, Percent_Identity=29.0322580645161, Blast_Score=65, Evalue=4e-11, Organism=Caenorhabditis elegans, GI25152911, Length=226, Percent_Identity=29.646017699115, Blast_Score=64, Evalue=5e-11, Organism=Caenorhabditis elegans, GI17564282, Length=192, Percent_Identity=26.0416666666667, Blast_Score=64, Evalue=5e-11, Organism=Caenorhabditis elegans, GI17538182, Length=258, Percent_Identity=27.5193798449612, Blast_Score=64, Evalue=6e-11, Organism=Caenorhabditis elegans, GI17560220, Length=270, Percent_Identity=30, Blast_Score=64, Evalue=6e-11, Organism=Saccharomyces cerevisiae, GI6322861, Length=253, Percent_Identity=26.8774703557312, Blast_Score=72, Evalue=7e-14, Organism=Saccharomyces cerevisiae, GI6324126, Length=247, Percent_Identity=25.5060728744939, Blast_Score=68, Evalue=1e-12, Organism=Saccharomyces cerevisiae, GI6322067, Length=193, Percent_Identity=29.5336787564767, Blast_Score=62, Evalue=7e-11, Organism=Drosophila melanogaster, GI21357041, Length=252, Percent_Identity=33.7301587301587, Blast_Score=122, Evalue=3e-28, Organism=Drosophila melanogaster, GI28571526, Length=252, Percent_Identity=34.5238095238095, Blast_Score=120, Evalue=7e-28, Organism=Drosophila melanogaster, GI23397609, Length=251, Percent_Identity=33.4661354581673, Blast_Score=108, Evalue=2e-24, Organism=Drosophila melanogaster, GI24644339, Length=251, Percent_Identity=31.8725099601594, Blast_Score=102, Evalue=2e-22, Organism=Drosophila melanogaster, GI24643142, Length=249, Percent_Identity=31.3253012048193, Blast_Score=98, Evalue=6e-21, Organism=Drosophila melanogaster, GI21355319, Length=249, Percent_Identity=29.718875502008, Blast_Score=94, Evalue=7e-20, Organism=Drosophila melanogaster, GI21357673, Length=195, Percent_Identity=32.3076923076923, Blast_Score=86, Evalue=2e-17, Organism=Drosophila melanogaster, GI24639444, Length=247, Percent_Identity=30.3643724696356, Blast_Score=86, Evalue=2e-17, Organism=Drosophila melanogaster, GI24644337, Length=259, Percent_Identity=31.2741312741313, Blast_Score=82, Evalue=2e-16, Organism=Drosophila melanogaster, GI24580925, Length=204, Percent_Identity=32.843137254902, Blast_Score=77, Evalue=1e-14, Organism=Drosophila melanogaster, GI24640492, Length=194, Percent_Identity=28.3505154639175, Blast_Score=75, Evalue=5e-14, Organism=Drosophila melanogaster, GI21355631, Length=216, Percent_Identity=26.3888888888889, Blast_Score=71, Evalue=6e-13, Organism=Drosophila melanogaster, GI24584748, Length=175, Percent_Identity=30.8571428571429, Blast_Score=69, Evalue=3e-12, Organism=Drosophila melanogaster, GI161076933, Length=175, Percent_Identity=30.8571428571429, Blast_Score=69, Evalue=3e-12, Organism=Drosophila melanogaster, GI17737361, Length=260, Percent_Identity=28.0769230769231, Blast_Score=67, Evalue=9e-12, Organism=Drosophila melanogaster, GI24649181, Length=156, Percent_Identity=28.8461538461538, Blast_Score=65, Evalue=3e-11, Organism=Drosophila melanogaster, GI281364892, Length=200, Percent_Identity=27.5, Blast_Score=65, Evalue=4e-11, Organism=Drosophila melanogaster, GI24640442, Length=195, Percent_Identity=28.2051282051282, Blast_Score=64, Evalue=9e-11,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR011284 - InterPro: IPR002198 - InterPro: IPR002347 - InterPro: IPR016040 - InterPro: IPR020904 [H]
Pfam domain/function: PF00106 adh_short [H]
EC number: =1.1.1.100 [H]
Molecular weight: Translated: 25834; Mature: 25834
Theoretical pI: Translated: 4.89; Mature: 4.89
Prosite motif: PS00061 ADH_SHORT
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.8 %Cys (Translated Protein) 3.6 %Met (Translated Protein) 4.5 %Cys+Met (Translated Protein) 0.8 %Cys (Mature Protein) 3.6 %Met (Mature Protein) 4.5 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MFDLTDRVVLVTGGSRGLGREIAFGAARCGADVVIASRSLETCEATAAEIAEATGRTAMP CCCCCCCEEEEECCCCCCCHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHCCCCCCC YEVHVGRWDQLDGLVSAVYERFGKLDVLVNNAGMSPLYESLTSVTEKLFDAVFNLNVKGP EEEECCCCHHHHHHHHHHHHHHCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCCH FRLAALIGERMVADGGGTIVNVSSSGSIRPDPHMLPYAAAKAGLNAMTEGLAQAYGPTVR HHHHHHHHHHHEECCCCEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCEEE VNTLMAGPFLTDVSKAWDFSGTENPFGHMALKRAGDPAEIVGAALFLMSNASSFTTGAIL EEEEECCCHHHHHHHHCCCCCCCCCHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCEEE RADGGIP ECCCCCC >Mature Secondary Structure MFDLTDRVVLVTGGSRGLGREIAFGAARCGADVVIASRSLETCEATAAEIAEATGRTAMP CCCCCCCEEEEECCCCCCCHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHCCCCCCC YEVHVGRWDQLDGLVSAVYERFGKLDVLVNNAGMSPLYESLTSVTEKLFDAVFNLNVKGP EEEECCCCHHHHHHHHHHHHHHCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCCH FRLAALIGERMVADGGGTIVNVSSSGSIRPDPHMLPYAAAKAGLNAMTEGLAQAYGPTVR HHHHHHHHHHHEECCCCEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCEEE VNTLMAGPFLTDVSKAWDFSGTENPFGHMALKRAGDPAEIVGAALFLMSNASSFTTGAIL EEEEECCCHHHHHHHHCCCCCCCCCHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCEEE RADGGIP ECCCCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 10360571 [H]