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The map label for this gene is soxB [H]

Identifier: 119871012

GI number: 119871012

Start: 5224531

End: 5225727

Strand: Direct

Name: soxB [H]

Synonym: Mkms_4985

Alternate gene names: 119871012

Gene position: 5224531-5225727 (Clockwise)

Preceding gene: 119871011

Following gene: 119871013

Centisome position: 91.06

GC content: 69.26

Gene sequence:

>1197_bases
ATGATCGAAACAGCTGACGTCGTCATCGTCGGCGGCGGTCTGGAGGGCGCCGCCGCCGCGTGGGCGTTGGCCGAGCGCGG
GATCACGAATGTGGTTGTGGTCGAACGGAATACCGTCGGGTCCGGGATGACGGGTAAATCGAGCGGTATCGTGCGCTGCC
ACTACGGGGTCAGCTCGCTGGCCGCCATGGCCAACGCCGGACTCGAGGTGTTCGAGAACCCGCAGAAGTACCTGGGCGAG
CAGGCCGACGACATCGGATTCCGCCAGACCGGATACGTCGTCGGGGTCGGCGAGCCGAACGTCGGCGCGATGCGCAAGAG
CCTCGCGGCGCAGCGCGCGGTCGGTGTGCAGACCGAGGAGATCGACGCCGCAGAGGTCGCCGAGATGTGGCCGTTCGCCG
ACCTAGAACCGTTCGCGGCGTTCGGCTGGGAGCCCCGCGGCGGATACGGCGATGCCTATCGGACCGCCCAGGCGTTCGCG
GCGGCCGCCCGGTCCGCGGGTGTGCGCGTGCGGCAGAGCACCGCGGTGCAGAACCTGACGACCGTCGGCGACCGCGTCAC
CGGCGTGAAGCTGGCCGACGGCGGCGAGATCTCCGCCGAGACCGTCGTCGTCGCCACCGGAGCCTGGACCCGGCCATTCC
TCGCCCAGCACGGGATCGACGTGCCGATCCGCGTGGTGCGCGAACAGATCGTGCTCATCGACCCCGGTGTGGAACTCGGT
CCGGTGCCGGTGTTCTCCGATCTGGTGTCGCTGCAGTACATCCGCCCCGAACCCGACGGCACAGTGCTGTTCGGCAACAG
CGACCTGGCCGACAACGAGGAGACGGACCCGGACGACTACCTCAACCGCGCCACCGACGACTTCGTCGACATCACCGTCG
ACAAGGTCGGCACCCGGTTCCCCGGTTTCCCCGACGCCTCGATCACCAGCAGCTACGCCGGCTGTTACGACGTCACACCC
GATTGGAACCCGGTGATCTCCCGCACCGAACTCGACGGTCTCGTCGTCGCGGCGGGGTTCAGCGGCCACGGCTTCAAGAT
CGCTCCCGCGGTCGGCCGGTTGGTGGCGGACATCGTCGTCGACGGGCGCAGCGGCGACCCGCGGATCCCGGAGACCGATT
TCCGGCTGTCCCGCTTCGCCGAGGGCGACCTGCTCCGCACGCCCTACCCGTACGTCGGTGCCGGCGAGATGCGCTAG

Upstream 100 bases:

>100_bases
ACGTCTGCCATCTCGAACCCGAGGATCTGGTGGCCGTCAGCATCGAAGCCGCGGCCATGGCCCGCGTTCCGCTGGCCGGC
ACCGACTGGATTCCCGGCCG

Downstream 100 bases:

>100_bases
ACAGGGTGCCGTGAGCCCATCCGAGGATTCTGCGCCGCTGCTGCGCAACAAGTCGGGCACCGCGCGCGAGCGTGACCCGC
AGGAACCGGTCGACGACACC

Product: FAD dependent oxidoreductase

Products: NA

Alternate protein names: Sarcosine oxidase subunit B [H]

Number of amino acids: Translated: 398; Mature: 398

Protein sequence:

>398_residues
MIETADVVIVGGGLEGAAAAWALAERGITNVVVVERNTVGSGMTGKSSGIVRCHYGVSSLAAMANAGLEVFENPQKYLGE
QADDIGFRQTGYVVGVGEPNVGAMRKSLAAQRAVGVQTEEIDAAEVAEMWPFADLEPFAAFGWEPRGGYGDAYRTAQAFA
AAARSAGVRVRQSTAVQNLTTVGDRVTGVKLADGGEISAETVVVATGAWTRPFLAQHGIDVPIRVVREQIVLIDPGVELG
PVPVFSDLVSLQYIRPEPDGTVLFGNSDLADNEETDPDDYLNRATDDFVDITVDKVGTRFPGFPDASITSSYAGCYDVTP
DWNPVISRTELDGLVVAAGFSGHGFKIAPAVGRLVADIVVDGRSGDPRIPETDFRLSRFAEGDLLRTPYPYVGAGEMR

Sequences:

>Translated_398_residues
MIETADVVIVGGGLEGAAAAWALAERGITNVVVVERNTVGSGMTGKSSGIVRCHYGVSSLAAMANAGLEVFENPQKYLGE
QADDIGFRQTGYVVGVGEPNVGAMRKSLAAQRAVGVQTEEIDAAEVAEMWPFADLEPFAAFGWEPRGGYGDAYRTAQAFA
AAARSAGVRVRQSTAVQNLTTVGDRVTGVKLADGGEISAETVVVATGAWTRPFLAQHGIDVPIRVVREQIVLIDPGVELG
PVPVFSDLVSLQYIRPEPDGTVLFGNSDLADNEETDPDDYLNRATDDFVDITVDKVGTRFPGFPDASITSSYAGCYDVTP
DWNPVISRTELDGLVVAAGFSGHGFKIAPAVGRLVADIVVDGRSGDPRIPETDFRLSRFAEGDLLRTPYPYVGAGEMR
>Mature_398_residues
MIETADVVIVGGGLEGAAAAWALAERGITNVVVVERNTVGSGMTGKSSGIVRCHYGVSSLAAMANAGLEVFENPQKYLGE
QADDIGFRQTGYVVGVGEPNVGAMRKSLAAQRAVGVQTEEIDAAEVAEMWPFADLEPFAAFGWEPRGGYGDAYRTAQAFA
AAARSAGVRVRQSTAVQNLTTVGDRVTGVKLADGGEISAETVVVATGAWTRPFLAQHGIDVPIRVVREQIVLIDPGVELG
PVPVFSDLVSLQYIRPEPDGTVLFGNSDLADNEETDPDDYLNRATDDFVDITVDKVGTRFPGFPDASITSSYAGCYDVTP
DWNPVISRTELDGLVVAAGFSGHGFKIAPAVGRLVADIVVDGRSGDPRIPETDFRLSRFAEGDLLRTPYPYVGAGEMR

Specific function: Catalyzes the oxidative demethylation of sarcosine to yield glycine, hydrogen peroxide and 5,10- methylenetetrahydrofolate [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the soxB family [H]

Homologues:

Organism=Homo sapiens, GI24797151, Length=376, Percent_Identity=23.936170212766, Blast_Score=97, Evalue=3e-20,
Organism=Homo sapiens, GI8923708, Length=403, Percent_Identity=25.8064516129032, Blast_Score=97, Evalue=3e-20,
Organism=Homo sapiens, GI197927446, Length=387, Percent_Identity=21.4470284237726, Blast_Score=86, Evalue=6e-17,
Organism=Homo sapiens, GI21361378, Length=387, Percent_Identity=21.4470284237726, Blast_Score=86, Evalue=6e-17,
Organism=Homo sapiens, GI194306651, Length=386, Percent_Identity=22.5388601036269, Blast_Score=66, Evalue=7e-11,
Organism=Escherichia coli, GI1787559, Length=419, Percent_Identity=24.1050119331742, Blast_Score=79, Evalue=7e-16,
Organism=Caenorhabditis elegans, GI71994045, Length=374, Percent_Identity=21.6577540106952, Blast_Score=66, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI71994052, Length=381, Percent_Identity=21.5223097112861, Blast_Score=66, Evalue=4e-11,
Organism=Drosophila melanogaster, GI20130091, Length=389, Percent_Identity=26.2210796915167, Blast_Score=107, Evalue=2e-23,
Organism=Drosophila melanogaster, GI28571104, Length=377, Percent_Identity=23.0769230769231, Blast_Score=86, Evalue=4e-17,
Organism=Drosophila melanogaster, GI20129729, Length=391, Percent_Identity=25.8312020460358, Blast_Score=84, Evalue=2e-16,
Organism=Drosophila melanogaster, GI17985989, Length=400, Percent_Identity=25, Blast_Score=67, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006076
- InterPro:   IPR006278 [H]

Pfam domain/function: PF01266 DAO [H]

EC number: =1.5.3.1 [H]

Molecular weight: Translated: 42146; Mature: 42146

Theoretical pI: Translated: 4.24; Mature: 4.24

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIETADVVIVGGGLEGAAAAWALAERGITNVVVVERNTVGSGMTGKSSGIVRCHYGVSSL
CCCCCCEEEECCCCCHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCEEEEECCHHHH
AAMANAGLEVFENPQKYLGEQADDIGFRQTGYVVGVGEPNVGAMRKSLAAQRAVGVQTEE
HHHHHCCHHHHCCHHHHHCCCCCCCCCEECCEEEECCCCCHHHHHHHHHHHHHCCCCHHC
IDAAEVAEMWPFADLEPFAAFGWEPRGGYGDAYRTAQAFAAAARSAGVRVRQSTAVQNLT
CCHHHHHHHCCCCCCCHHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCCEEEHHHHHHHHH
TVGDRVTGVKLADGGEISAETVVVATGAWTRPFLAQHGIDVPIRVVREQIVLIDPGVELG
HHCCCEEEEEEECCCCCCCCEEEEECCCCCCHHHHHCCCCCHHHEECCEEEEECCCCCCC
PVPVFSDLVSLQYIRPEPDGTVLFGNSDLADNEETDPDDYLNRATDDFVDITVDKVGTRF
CCHHHHHHHHEEEECCCCCCEEEECCCCCCCCCCCCHHHHHHHCCCCCEEEEHHHHCCCC
PGFPDASITSSYAGCYDVTPDWNPVISRTELDGLVVAAGFSGHGFKIAPAVGRLVADIVV
CCCCCCHHHCCCCCEEECCCCCCCCCCCCCCCCEEEEECCCCCCEEEHHHHHHHHHHHEE
DGRSGDPRIPETDFRLSRFAEGDLLRTPYPYVGAGEMR
ECCCCCCCCCCCCCHHHHHCCCCEECCCCCCCCCCCCC
>Mature Secondary Structure
MIETADVVIVGGGLEGAAAAWALAERGITNVVVVERNTVGSGMTGKSSGIVRCHYGVSSL
CCCCCCEEEECCCCCHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCEEEEECCHHHH
AAMANAGLEVFENPQKYLGEQADDIGFRQTGYVVGVGEPNVGAMRKSLAAQRAVGVQTEE
HHHHHCCHHHHCCHHHHHCCCCCCCCCEECCEEEECCCCCHHHHHHHHHHHHHCCCCHHC
IDAAEVAEMWPFADLEPFAAFGWEPRGGYGDAYRTAQAFAAAARSAGVRVRQSTAVQNLT
CCHHHHHHHCCCCCCCHHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCCEEEHHHHHHHHH
TVGDRVTGVKLADGGEISAETVVVATGAWTRPFLAQHGIDVPIRVVREQIVLIDPGVELG
HHCCCEEEEEEECCCCCCCCEEEEECCCCCCHHHHHCCCCCHHHEECCEEEEECCCCCCC
PVPVFSDLVSLQYIRPEPDGTVLFGNSDLADNEETDPDDYLNRATDDFVDITVDKVGTRF
CCHHHHHHHHEEEECCCCCCEEEECCCCCCCCCCCCHHHHHHHCCCCCEEEEHHHHCCCC
PGFPDASITSSYAGCYDVTPDWNPVISRTELDGLVVAAGFSGHGFKIAPAVGRLVADIVV
CCCCCCHHHCCCCCEEECCCCCCCCCCCCCCCCEEEEECCCCCCEEEHHHHHHHHHHHEE
DGRSGDPRIPETDFRLSRFAEGDLLRTPYPYVGAGEMR
ECCCCCCCCCCCCCHHHHHCCCCEECCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7543100; 1939012; 3202887; 7692961 [H]