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The map label for this gene is atoD [C]

Identifier: 119870798

GI number: 119870798

Start: 5001614

End: 5002501

Strand: Direct

Name: atoD [C]

Synonym: Mkms_4770

Alternate gene names: 119870798

Gene position: 5001614-5002501 (Clockwise)

Preceding gene: 119870797

Following gene: 119870799

Centisome position: 87.18

GC content: 65.99

Gene sequence:

>888_bases
ATGACCGATAAGACAACGAGTCTCGACGAGGCCGTCGCGTCCGTCGAGAGCGGGATGACCATCGGCATCGGCGGTTGGGG
CTCACGCCGCAAGCCGATGGCGCTCATCCGTGCGCTGCTGCGCACCGATGTCACCGATCTCACCGTCGTCACCTACGGCG
GACCGGACCTCGGGCTGCTGTGCTCGGCGAACAAGGTCAAACGGGTCTACTACGGTTTCGTATCGCTGGATTCACCCCCG
TTCTACGACCCCTGGTTCTCCAAGGCGCGCACCAGCGGATCGATCGAGGCGCGCGAGATGGACGAGGGCATGCTGCGGTG
CGGTCTGCAGGCCGCCGCACAACGCCTGCCGTTCCTGCCGATCCGCGCCGGACTCGGCAGCGACGTCCGCAAGTTCTGGG
GCGACGAGCTCAAGACCGTGCGCTCGCCCTATCCGACCGGTCAGGGCTACGAGGAACTGATCGCGATGCCCGCGCTCAAC
CTCGACGTGGCGCTGGTACACCTCAACGTCGGTGACGCGCAGGGCAACGCCGCCTACACCGGCATCGACCCCTACTTCGA
CGACCTGTTCCTGATGTCGGCGCAGAATCGGCTGATGAGCGTCGAGAAGGTGGTGTCCACCGAGGAGCTCGTCAAAGCCG
TTCCGCCACAGGCGCTGCTGGTGAACCGGATGATGGTCGACTCCGTCGTCGAAGCCCCCAACGGAGCGCACTTCACCACC
GCCGAACCGGACTACCGCCGCGACGAGAAGTTCCAGCGGCACTACGCCGAGGCCGCCGGGTCCGACGAGTCCTGGGCCGA
GTTCGTCGGCACATACCTTTCGGGCAGCGAGGACGACTACCAGGCCGCGGTCCGGAAGTTCGCCGAAGAGCAGGGAGCCG
CGAAATGA

Upstream 100 bases:

>100_bases
GATACCGCATGGAGCAGGGCTTCACATTCGAGCTGAACCTGGCAGGAGTGTCCGACGAGCACCGCGACGCCTTCGCCGGG
ACATCGAAGGGCGAGACGAA

Downstream 100 bases:

>100_bases
CCGAGCCGACCCGCGCCGAGGTGTGCGCCGTCGCGTGTGCCGAGCTGTTCCGCGACGCCGGTGAGATCATGGTCAGCCCG
ATGGCGAACATGGTGTCGAT

Product: coenzyme A transferase

Products: Acetate; Butanoyl-CoA [C]

Alternate protein names: NA

Number of amino acids: Translated: 295; Mature: 294

Protein sequence:

>295_residues
MTDKTTSLDEAVASVESGMTIGIGGWGSRRKPMALIRALLRTDVTDLTVVTYGGPDLGLLCSANKVKRVYYGFVSLDSPP
FYDPWFSKARTSGSIEAREMDEGMLRCGLQAAAQRLPFLPIRAGLGSDVRKFWGDELKTVRSPYPTGQGYEELIAMPALN
LDVALVHLNVGDAQGNAAYTGIDPYFDDLFLMSAQNRLMSVEKVVSTEELVKAVPPQALLVNRMMVDSVVEAPNGAHFTT
AEPDYRRDEKFQRHYAEAAGSDESWAEFVGTYLSGSEDDYQAAVRKFAEEQGAAK

Sequences:

>Translated_295_residues
MTDKTTSLDEAVASVESGMTIGIGGWGSRRKPMALIRALLRTDVTDLTVVTYGGPDLGLLCSANKVKRVYYGFVSLDSPP
FYDPWFSKARTSGSIEAREMDEGMLRCGLQAAAQRLPFLPIRAGLGSDVRKFWGDELKTVRSPYPTGQGYEELIAMPALN
LDVALVHLNVGDAQGNAAYTGIDPYFDDLFLMSAQNRLMSVEKVVSTEELVKAVPPQALLVNRMMVDSVVEAPNGAHFTT
AEPDYRRDEKFQRHYAEAAGSDESWAEFVGTYLSGSEDDYQAAVRKFAEEQGAAK
>Mature_294_residues
TDKTTSLDEAVASVESGMTIGIGGWGSRRKPMALIRALLRTDVTDLTVVTYGGPDLGLLCSANKVKRVYYGFVSLDSPPF
YDPWFSKARTSGSIEAREMDEGMLRCGLQAAAQRLPFLPIRAGLGSDVRKFWGDELKTVRSPYPTGQGYEELIAMPALNL
DVALVHLNVGDAQGNAAYTGIDPYFDDLFLMSAQNRLMSVEKVVSTEELVKAVPPQALLVNRMMVDSVVEAPNGAHFTTA
EPDYRRDEKFQRHYAEAAGSDESWAEFVGTYLSGSEDDYQAAVRKFAEEQGAAK

Specific function: Probable subunit of a CoA-transferase composed of Rv3551 and Rv3552 [H]

COG id: COG1788

COG function: function code I; Acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 3-oxoacid CoA-transferase subunit A family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004165 [H]

Pfam domain/function: PF01144 CoA_trans [H]

EC number: 2.8.3.8 [C]

Molecular weight: Translated: 32314; Mature: 32183

Theoretical pI: Translated: 4.62; Mature: 4.62

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDKTTSLDEAVASVESGMTIGIGGWGSRRKPMALIRALLRTDVTDLTVVTYGGPDLGLL
CCCCCCHHHHHHHHHHCCCEEEECCCCCCCCHHHHHHHHHHCCCCCEEEEEECCCCCEEE
CSANKVKRVYYGFVSLDSPPFYDPWFSKARTSGSIEAREMDEGMLRCGLQAAAQRLPFLP
ECCHHHHHHEEEEEECCCCCCCCHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCEE
IRAGLGSDVRKFWGDELKTVRSPYPTGQGYEELIAMPALNLDVALVHLNVGDAQGNAAYT
ECCCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHCCCCCCEEEEEEEEECCCCCCEEEC
GIDPYFDDLFLMSAQNRLMSVEKVVSTEELVKAVPPQALLVNRMMVDSVVEAPNGAHFTT
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCEECC
AEPDYRRDEKFQRHYAEAAGSDESWAEFVGTYLSGSEDDYQAAVRKFAEEQGAAK
CCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
TDKTTSLDEAVASVESGMTIGIGGWGSRRKPMALIRALLRTDVTDLTVVTYGGPDLGLL
CCCCCHHHHHHHHHHCCCEEEECCCCCCCCHHHHHHHHHHCCCCCEEEEEECCCCCEEE
CSANKVKRVYYGFVSLDSPPFYDPWFSKARTSGSIEAREMDEGMLRCGLQAAAQRLPFLP
ECCHHHHHHEEEEEECCCCCCCCHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCEE
IRAGLGSDVRKFWGDELKTVRSPYPTGQGYEELIAMPALNLDVALVHLNVGDAQGNAAYT
ECCCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHCCCCCCEEEEEEEEECCCCCCEEEC
GIDPYFDDLFLMSAQNRLMSVEKVVSTEELVKAVPPQALLVNRMMVDSVVEAPNGAHFTT
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCEECC
AEPDYRRDEKFQRHYAEAAGSDESWAEFVGTYLSGSEDDYQAAVRKFAEEQGAAK
CCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Acetyl-CoA; Butyrate [C]

Specific reaction: Acetyl-CoA + Butyrate (n-C4:0) --> Acetate + Butanoyl-CoA [C]

General reaction: Coenzyme A transfer [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]