Click here to switch to the map view.

The map label for this gene is degU [H]

Identifier: 119870771

GI number: 119870771

Start: 4970874

End: 4971512

Strand: Direct

Name: degU [H]

Synonym: Mkms_4742

Alternate gene names: 119870771

Gene position: 4970874-4971512 (Clockwise)

Preceding gene: 119870765

Following gene: 119870773

Centisome position: 86.64

GC content: 69.33

Gene sequence:

>639_bases
GTGATCGTCGACGATCACGAATTGTTCGCCGAGGGTCTGGAACTGCTGCTGGCCCGCGACTGGTCGGAGCAGTTCGTGAT
CGGTGGCCGGACCACCTTCGTCGAAGAGGCCGCTGAACTGGCCACGTCGTGCGATGCCGACCTCGCGATCGTGGACCTGT
CGATGCCGCCGCTGGGTGGGGTGGCGGCGATTCGGCACATCCGGGCGCGCCATCCCCGAACCCGCATCCTGGCGCTGTCG
GGCACCGGCGACATGCAACTCGCCGAGGACGCGCTGCGCGCGGGCGCCGACGGGTTCCTGTCCAAGACGGTGCGGCCCGA
GGCCCTGGTCGGGCCGTTGACGACGATCGCCGCCGGATTGCGGGTGGTGGACCCCGCTCTGCTGGATGCGCTGCTCTCGG
GTACGCGCAAACCGTCGCCCGAGGTGTTGACGGCGCTGACCCCGGCAGACCTCAAACTGTGGGTGCTGGTCTCCACGGGG
ATGGAGACCGCCGACATCGCCACCCGGATGATGGTGTCCGACCGTACCGCCAAACGGATGGTGGCCTCGCTGTTGAACAA
GCTGGGCGTCGGCAACCGGATCGCCGCCGCCGCGTTGGCGGGGCGGAGCGGGATCCTCGACGATCTCGCCGAGGGGTGA

Upstream 100 bases:

>100_bases
TGACCTCAGTCGACGCGAGCCGTTCACGGGGCCGACCCTAGACCCGCGCACTACGATCCAGCGGGTGACTCACAGGTCCG
GACGAGAACCCCTCGTCGTC

Downstream 100 bases:

>100_bases
ACGGCGGCGTCAGGGATCCACACGCAACGCCTGCGCAGGGCACATGGCGGCGGCACGGACGACGGCCCCGCGCTCGCTCT
GGGGCGGATCGGGGTCGAGA

Product: two component LuxR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 212; Mature: 212

Protein sequence:

>212_residues
MIVDDHELFAEGLELLLARDWSEQFVIGGRTTFVEEAAELATSCDADLAIVDLSMPPLGGVAAIRHIRARHPRTRILALS
GTGDMQLAEDALRAGADGFLSKTVRPEALVGPLTTIAAGLRVVDPALLDALLSGTRKPSPEVLTALTPADLKLWVLVSTG
METADIATRMMVSDRTAKRMVASLLNKLGVGNRIAAAALAGRSGILDDLAEG

Sequences:

>Translated_212_residues
MIVDDHELFAEGLELLLARDWSEQFVIGGRTTFVEEAAELATSCDADLAIVDLSMPPLGGVAAIRHIRARHPRTRILALS
GTGDMQLAEDALRAGADGFLSKTVRPEALVGPLTTIAAGLRVVDPALLDALLSGTRKPSPEVLTALTPADLKLWVLVSTG
METADIATRMMVSDRTAKRMVASLLNKLGVGNRIAAAALAGRSGILDDLAEG
>Mature_212_residues
MIVDDHELFAEGLELLLARDWSEQFVIGGRTTFVEEAAELATSCDADLAIVDLSMPPLGGVAAIRHIRARHPRTRILALS
GTGDMQLAEDALRAGADGFLSKTVRPEALVGPLTTIAAGLRVVDPALLDALLSGTRKPSPEVLTALTPADLKLWVLVSTG
METADIATRMMVSDRTAKRMVASLLNKLGVGNRIAAAALAGRSGILDDLAEG

Specific function: Regulating factor for the production of extracellular proteases. The N-terminal region acts as an inhibitor, whereas the C-terminal region carries enhancing activity [H]

COG id: COG2197

COG function: function code TK; Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788222, Length=209, Percent_Identity=24.8803827751196, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI1787473, Length=209, Percent_Identity=29.6650717703349, Blast_Score=69, Evalue=2e-13,
Organism=Escherichia coli, GI1786747, Length=190, Percent_Identity=22.1052631578947, Blast_Score=65, Evalue=4e-12,
Organism=Escherichia coli, GI1788521, Length=204, Percent_Identity=29.4117647058824, Blast_Score=64, Evalue=5e-12,
Organism=Escherichia coli, GI1790102, Length=200, Percent_Identity=29, Blast_Score=62, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR000792
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00196 GerE; PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 22317; Mature: 22317

Theoretical pI: Translated: 4.77; Mature: 4.77

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIVDDHELFAEGLELLLARDWSEQFVIGGRTTFVEEAAELATSCDADLAIVDLSMPPLGG
CCCCCHHHHHHHHHHHHHCCCCCCEEECCCHHHHHHHHHHHHCCCCCEEEEEECCCCCCH
VAAIRHIRARHPRTRILALSGTGDMQLAEDALRAGADGFLSKTVRPEALVGPLTTIAAGL
HHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHHCCCCHHHHHCCCCHHHHHHHHHHHHHH
RVVDPALLDALLSGTRKPSPEVLTALTPADLKLWVLVSTGMETADIATRMMVSDRTAKRM
HHHHHHHHHHHHHCCCCCCCHHEEEECCCCEEEEEEEECCCCHHHHHHHHHHHHHHHHHH
VASLLNKLGVGNRIAAAALAGRSGILDDLAEG
HHHHHHHCCCCCHHHHHHHHCCCCCHHHHCCC
>Mature Secondary Structure
MIVDDHELFAEGLELLLARDWSEQFVIGGRTTFVEEAAELATSCDADLAIVDLSMPPLGG
CCCCCHHHHHHHHHHHHHCCCCCCEEECCCHHHHHHHHHHHHCCCCCEEEEEECCCCCCH
VAAIRHIRARHPRTRILALSGTGDMQLAEDALRAGADGFLSKTVRPEALVGPLTTIAAGL
HHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHHCCCCHHHHHCCCCHHHHHHHHHHHHHH
RVVDPALLDALLSGTRKPSPEVLTALTPADLKLWVLVSTGMETADIATRMMVSDRTAKRM
HHHHHHHHHHHHHCCCCCCCHHEEEECCCCEEEEEEEECCCCHHHHHHHHHHHHHHHHHH
VASLLNKLGVGNRIAAAALAGRSGILDDLAEG
HHHHHHHCCCCCHHHHHHHHCCCCCHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7765823 [H]