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The map label for this gene is msrR [H]

Identifier: 119870629

GI number: 119870629

Start: 4829558

End: 4831657

Strand: Direct

Name: msrR [H]

Synonym: Mkms_4600

Alternate gene names: 119870629

Gene position: 4829558-4831657 (Clockwise)

Preceding gene: 119870628

Following gene: 119870630

Centisome position: 84.18

GC content: 68.14

Gene sequence:

>2100_bases
ATGAGTGACGGCGACAGCCCTGGAGCTGGTGCCACACCCGACCCTCGGCGTCCCGACGAGCCGAGGTCCGACTGGGACAA
CCAATGGCTTACCCGATCCGGGCGGCGATCAGCGGGTGCCGCGCCGTGGGAGCGCAGTGAACCGCTCAAACGTCGGCAGT
CCGAACCGGAAGCCGACGAGACGGAGGAACCCGAGGAGTCCGGGCCCGATGAGTCCGGAGGCAGCCACACCGCTGGTGTG
GTCACCGTCGCCGACCTGATCGCCAAACTCAACGGCGACGGCAGCGCCCCGGCGGAGCTGACACCGAAACGCCGGCGCGC
CGAGCCAGAACCGGAGCCACCCGCCCCGGAGACGGAGATCATCGAGGCGATCCGCGAACCCGTCCGTGAACCGGCCGATC
CGGACCGCCAGGACACCGAGATCATCCCCGCCGCGACCAGCGCCTATGCCGCCGACCTGCCCGTCCTGGCCGAGGATCCG
GGTGACCGGGTGCCGCCGTACCGGGTCGGGGACGGCGGCACCGTCGTCGCCGAGGACGAACCGCACCGGCGCCGCCGGAT
CATCCTGGCCGGACGCGCCGCGGCCGCGCTGCTGGCGGTGCTCGCGCTGGTGCTCACCGGCGGCGCCTGGCAGTGGCAGA
CGTCGAAGAACGGCCTCATGAACAGGGTGTCGGCGCTGGACCAGGAGAGCCGCGACATCGTCGATCCGAACGCACAGTTC
GGCGACGAGAACTTCCTGATCGTCGGTGTGGACAGTCGCATCGGCGAGAACAGCGGCATGGGCGCGGGGACCACCGACGA
CGCCGCCGGCGCCAGGTCGGATACCGTGATGCTGGTCAATATCCCGGCCAACCGGAAACGCGTGGTGGCGGTGTCCTTCC
CCCGCGACCTGTCCATCGATCCCATGGAGTGCGAGCCCTGGAACCCGGAGACCGGTGCCTACGGCCCGATCACCGACCCG
GAGTCGCCGATGTACGGGCGCGAAACGGTCTACACCGAGTACAAACTCAACTCGGCGTACGCGGTCGGCGGGCCGAAGTG
CCTGGTCAAGGTCGTGCAGAAGCTCTCGGGCCTGTCGGTGAACCGGTTCATGGCCGTCGACTTCGCCGGGTTCTCCAAGA
TGGTCGACGCCCTGGGCGGTGTCGAGGTCTGCAGCACCGAACCGCTGGAGGACTACGAACTCGGCACGGTGCTGCCGACC
GCCGGACGCCAGATGGTCGACGGGCACACCGCGCTCAACTACGTCCGCGCCCGCCAGGTCACCACCGAGATCAACGGCGA
CTACGGCCGCATCAAGCGCCAGCAGCGGTTCCTGTCGTCGCTGCTGCGTTCGCTGATCTCCAAGGAGGTCTTCTTCTCGC
TGTCGAAGCTCAACAACGTGGTCAACATGTTCATCGACGACAGCTACGTCGACAACATCGACACCCGTGACCTGGTGACG
CTGGGCCAGTCGATCCAGGGCGTCACCGCGGGACGGATCAGCTTCGTCACCGTGCCGACCACCGGCTACGCCGACGAGTA
CGGCAACGAGACTCCCCGCACCGACGACATGCGTGCGCTGTTCACCGCGATCATCAACGACGATCCGCTGCCCGGGGAGA
AGAACCCCGACAACGTCCCGGGCACCCCGGAGTCGACGACGGCGGATCCCGAGGTCGCGGCGACCGAGTCCGGCGGTGCC
GAACTGGTCAACGCCGTCACCACCGAACCGCAGGACGTCACCGTGCAGGTGTCGAACTCCACCGGACAGACCGGTCTGGG
TGCGACGACCGCCGAGGAACTGCAGCAGTACGGCTTCAACGTCACGACCCCGGACGACTACCCGAGTGCGCTGACCGAGA
CGACGGTGTTCTTCTCCCCCGGTAACGAGCAGGCCGCGGCCACCGTTGCGTCGTCGTTCGCCAACCCGACCATCGAGCGG
GTCAGCGGTATGGGTGACATCGTCCAGGTCGTGCTCGGCAACGACTACAACGCCGTCGCCGCGCCCACACCCAGCGGCTC
ACCGGTCCAGGTGAACGTGTTGCACGACACCGGCAGCACACCCGCCCCGCTGCCGGAGGATCTCAACGTCACCAACGCCG
CCGACACCACCTGCGAGTGA

Upstream 100 bases:

>100_bases
GGAGTTCCCGAGGCGCTGCTACAAGACAGAGTGATCGCTTAGAAGAGGACGAGCACCGCGTGCGTTCGCGCGTGCACCAC
GCAAAGTCGGAGGCCGGTTG

Downstream 100 bases:

>100_bases
CCCGCTCCTCGGCGTTTCGGCAGGTGGCATTCACCTTCAGTTCACCCGCGGCTCCGTGACGGCGCACCGTCCTACCTCTA
GGCTGGACACATGCGGACCG

Product: cell envelope-related transcriptional attenuator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 699; Mature: 698

Protein sequence:

>699_residues
MSDGDSPGAGATPDPRRPDEPRSDWDNQWLTRSGRRSAGAAPWERSEPLKRRQSEPEADETEEPEESGPDESGGSHTAGV
VTVADLIAKLNGDGSAPAELTPKRRRAEPEPEPPAPETEIIEAIREPVREPADPDRQDTEIIPAATSAYAADLPVLAEDP
GDRVPPYRVGDGGTVVAEDEPHRRRRIILAGRAAAALLAVLALVLTGGAWQWQTSKNGLMNRVSALDQESRDIVDPNAQF
GDENFLIVGVDSRIGENSGMGAGTTDDAAGARSDTVMLVNIPANRKRVVAVSFPRDLSIDPMECEPWNPETGAYGPITDP
ESPMYGRETVYTEYKLNSAYAVGGPKCLVKVVQKLSGLSVNRFMAVDFAGFSKMVDALGGVEVCSTEPLEDYELGTVLPT
AGRQMVDGHTALNYVRARQVTTEINGDYGRIKRQQRFLSSLLRSLISKEVFFSLSKLNNVVNMFIDDSYVDNIDTRDLVT
LGQSIQGVTAGRISFVTVPTTGYADEYGNETPRTDDMRALFTAIINDDPLPGEKNPDNVPGTPESTTADPEVAATESGGA
ELVNAVTTEPQDVTVQVSNSTGQTGLGATTAEELQQYGFNVTTPDDYPSALTETTVFFSPGNEQAAATVASSFANPTIER
VSGMGDIVQVVLGNDYNAVAAPTPSGSPVQVNVLHDTGSTPAPLPEDLNVTNAADTTCE

Sequences:

>Translated_699_residues
MSDGDSPGAGATPDPRRPDEPRSDWDNQWLTRSGRRSAGAAPWERSEPLKRRQSEPEADETEEPEESGPDESGGSHTAGV
VTVADLIAKLNGDGSAPAELTPKRRRAEPEPEPPAPETEIIEAIREPVREPADPDRQDTEIIPAATSAYAADLPVLAEDP
GDRVPPYRVGDGGTVVAEDEPHRRRRIILAGRAAAALLAVLALVLTGGAWQWQTSKNGLMNRVSALDQESRDIVDPNAQF
GDENFLIVGVDSRIGENSGMGAGTTDDAAGARSDTVMLVNIPANRKRVVAVSFPRDLSIDPMECEPWNPETGAYGPITDP
ESPMYGRETVYTEYKLNSAYAVGGPKCLVKVVQKLSGLSVNRFMAVDFAGFSKMVDALGGVEVCSTEPLEDYELGTVLPT
AGRQMVDGHTALNYVRARQVTTEINGDYGRIKRQQRFLSSLLRSLISKEVFFSLSKLNNVVNMFIDDSYVDNIDTRDLVT
LGQSIQGVTAGRISFVTVPTTGYADEYGNETPRTDDMRALFTAIINDDPLPGEKNPDNVPGTPESTTADPEVAATESGGA
ELVNAVTTEPQDVTVQVSNSTGQTGLGATTAEELQQYGFNVTTPDDYPSALTETTVFFSPGNEQAAATVASSFANPTIER
VSGMGDIVQVVLGNDYNAVAAPTPSGSPVQVNVLHDTGSTPAPLPEDLNVTNAADTTCE
>Mature_698_residues
SDGDSPGAGATPDPRRPDEPRSDWDNQWLTRSGRRSAGAAPWERSEPLKRRQSEPEADETEEPEESGPDESGGSHTAGVV
TVADLIAKLNGDGSAPAELTPKRRRAEPEPEPPAPETEIIEAIREPVREPADPDRQDTEIIPAATSAYAADLPVLAEDPG
DRVPPYRVGDGGTVVAEDEPHRRRRIILAGRAAAALLAVLALVLTGGAWQWQTSKNGLMNRVSALDQESRDIVDPNAQFG
DENFLIVGVDSRIGENSGMGAGTTDDAAGARSDTVMLVNIPANRKRVVAVSFPRDLSIDPMECEPWNPETGAYGPITDPE
SPMYGRETVYTEYKLNSAYAVGGPKCLVKVVQKLSGLSVNRFMAVDFAGFSKMVDALGGVEVCSTEPLEDYELGTVLPTA
GRQMVDGHTALNYVRARQVTTEINGDYGRIKRQQRFLSSLLRSLISKEVFFSLSKLNNVVNMFIDDSYVDNIDTRDLVTL
GQSIQGVTAGRISFVTVPTTGYADEYGNETPRTDDMRALFTAIINDDPLPGEKNPDNVPGTPESTTADPEVAATESGGAE
LVNAVTTEPQDVTVQVSNSTGQTGLGATTAEELQQYGFNVTTPDDYPSALTETTVFFSPGNEQAAATVASSFANPTIERV
SGMGDIVQVVLGNDYNAVAAPTPSGSPVQVNVLHDTGSTPAPLPEDLNVTNAADTTCE

Specific function: Involved in sarA attenuation. Affects resistance to oxacillin and teicoplanin, as well as the synthesis of virulence factors [H]

COG id: COG1316

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cell membrane; Single-pass type II membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the LytR/CpsA/Psr regulatory protein family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004474 [H]

Pfam domain/function: PF03816 LytR_cpsA_psr [H]

EC number: NA

Molecular weight: Translated: 74607; Mature: 74476

Theoretical pI: Translated: 4.12; Mature: 4.12

Prosite motif: PS00041 HTH_ARAC_FAMILY_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDGDSPGAGATPDPRRPDEPRSDWDNQWLTRSGRRSAGAAPWERSEPLKRRQSEPEADE
CCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHCCCCCCCCCCCCCCCHHHHHCCCCCCCC
TEEPEESGPDESGGSHTAGVVTVADLIAKLNGDGSAPAELTPKRRRAEPEPEPPAPETEI
CCCCHHCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCHHHCCCCCCCCCCCHHHH
IEAIREPVREPADPDRQDTEIIPAATSAYAADLPVLAEDPGDRVPPYRVGDGGTVVAEDE
HHHHHHHHHCCCCCCCCCCEEECCCHHHHHCCCCEEECCCCCCCCCEEECCCCEEEECCC
PHRRRRIILAGRAAAALLAVLALVLTGGAWQWQTSKNGLMNRVSALDQESRDIVDPNAQF
CCCCCEEEEECHHHHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHHCCCCCCCCCCCC
GDENFLIVGVDSRIGENSGMGAGTTDDAAGARSDTVMLVNIPANRKRVVAVSFPRDLSID
CCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCEEEEEECCCCCCCC
PMECEPWNPETGAYGPITDPESPMYGRETVYTEYKLNSAYAVGGPKCLVKVVQKLSGLSV
CCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEEECCEEECCCHHHHHHHHHHHCCCCC
NRFMAVDFAGFSKMVDALGGVEVCSTEPLEDYELGTVLPTAGRQMVDGHTALNYVRARQV
CCEEEEEHHHHHHHHHHHCCCEEECCCCCCCCCCCEECCCCCCHHHCCHHHHHHHHHHHH
TTEINGDYGRIKRQQRFLSSLLRSLISKEVFFSLSKLNNVVNMFIDDSYVDNIDTRDLVT
HHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCHHHHH
LGQSIQGVTAGRISFVTVPTTGYADEYGNETPRTDDMRALFTAIINDDPLPGEKNPDNVP
HHHHHCCCCCCCEEEEEECCCCCHHHHCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCC
GTPESTTADPEVAATESGGAELVNAVTTEPQDVTVQVSNSTGQTGLGATTAEELQQYGFN
CCCCCCCCCCCCEECCCCCHHHHHHHCCCCCCEEEEEECCCCCCCCCCHHHHHHHHCCCC
VTTPDDYPSALTETTVFFSPGNEQAAATVASSFANPTIERVSGMGDIVQVVLGNDYNAVA
CCCCCCCCHHHHCEEEEECCCCCHHHHHHHHHHCCCHHHHHHCCCCEEHHEECCCCCEEE
APTPSGSPVQVNVLHDTGSTPAPLPEDLNVTNAADTTCE
CCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
SDGDSPGAGATPDPRRPDEPRSDWDNQWLTRSGRRSAGAAPWERSEPLKRRQSEPEADE
CCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHCCCCCCCCCCCCCCCHHHHHCCCCCCCC
TEEPEESGPDESGGSHTAGVVTVADLIAKLNGDGSAPAELTPKRRRAEPEPEPPAPETEI
CCCCHHCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCHHHCCCCCCCCCCCHHHH
IEAIREPVREPADPDRQDTEIIPAATSAYAADLPVLAEDPGDRVPPYRVGDGGTVVAEDE
HHHHHHHHHCCCCCCCCCCEEECCCHHHHHCCCCEEECCCCCCCCCEEECCCCEEEECCC
PHRRRRIILAGRAAAALLAVLALVLTGGAWQWQTSKNGLMNRVSALDQESRDIVDPNAQF
CCCCCEEEEECHHHHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHHCCCCCCCCCCCC
GDENFLIVGVDSRIGENSGMGAGTTDDAAGARSDTVMLVNIPANRKRVVAVSFPRDLSID
CCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCEEEEEECCCCCCCC
PMECEPWNPETGAYGPITDPESPMYGRETVYTEYKLNSAYAVGGPKCLVKVVQKLSGLSV
CCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEEECCEEECCCHHHHHHHHHHHCCCCC
NRFMAVDFAGFSKMVDALGGVEVCSTEPLEDYELGTVLPTAGRQMVDGHTALNYVRARQV
CCEEEEEHHHHHHHHHHHCCCEEECCCCCCCCCCCEECCCCCCHHHCCHHHHHHHHHHHH
TTEINGDYGRIKRQQRFLSSLLRSLISKEVFFSLSKLNNVVNMFIDDSYVDNIDTRDLVT
HHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCHHHHH
LGQSIQGVTAGRISFVTVPTTGYADEYGNETPRTDDMRALFTAIINDDPLPGEKNPDNVP
HHHHHCCCCCCCEEEEEECCCCCHHHHCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCC
GTPESTTADPEVAATESGGAELVNAVTTEPQDVTVQVSNSTGQTGLGATTAEELQQYGFN
CCCCCCCCCCCCEECCCCCHHHHHHHCCCCCCEEEEEECCCCCCCCCCHHHHHHHHCCCC
VTTPDDYPSALTETTVFFSPGNEQAAATVASSFANPTIERVSGMGDIVQVVLGNDYNAVA
CCCCCCCCHHHHCEEEEECCCCCHHHHHHHHHHCCCHHHHHHCCCCEEHHEECCCCCEEE
APTPSGSPVQVNVLHDTGSTPAPLPEDLNVTNAADTTCE
CCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12878519 [H]