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The map label for this gene is 119870588

Identifier: 119870588

GI number: 119870588

Start: 4790877

End: 4792577

Strand: Direct

Name: 119870588

Synonym: Mkms_4559

Alternate gene names: NA

Gene position: 4790877-4792577 (Clockwise)

Preceding gene: 119870586

Following gene: 119870589

Centisome position: 83.51

GC content: 71.02

Gene sequence:

>1701_bases
ATGGTGGACAATCGTGGCGTGGCCGGCGGACGCGATGAGAGTGACGGGGATCCCGAGGATTTCCGACGCGACGCCCGGTA
CTACCCGCCCCGGCCGCCCGCGGGCCACGACCACCCCGGCATGGCGAACTACCCCAGCGACGGCGGTACCTACCGGCGTC
CACGCAGGCAGCCGACGCCGAGCGCGAACCGCTGGCTGCCGCCGCTGGACGAGCCGACGCCCTCGGGGTACCAGTACGAC
CCACCGCCCGGTGTGGGTGCGGGCGCAGGGCGGGTCACCGTCACCCGCGCCGCGGCGCAGCGCAGCCGCGAGATGGGGTC
GAAGATGTACGGCCTGGTGCACCGGGCCGCGACCGCCGACGGGGCGGACAAGTCCGGGCTGACGGCGCTCACCTGGCCGG
TGGTGGCCAACTTCGCCGTCGACGCCGCCATGGCGGTGGCGTTGGCGAACACGTTGTTCTTCGCCGCCGCGAGCGGGGAG
AGCAAGAGCAAGGTCGCGCTGTACCTGCTGATCACGATCGCGCCGTTCGCGGTGATCGCACCGCTCATCGGCCCGGCGCT
CGACCGCCTGCAACATGGCCGCCGCGTCGCGTTGGCCGCCTCGTTCCTGGCGCGCACGGCGCTGGTGGTGCTGCTGATCG
CGAACTACGACGGCGAGACGGGCAGCTACCAGTCGTGGGTGCTCTACCCGTGCGCGCTCGGGATGATGGTGCTGTCGAAA
TCGTTCTCGGTGCTGCGCAGCGCCGTCACCCCGCGGGTGCTGCCCCCGAGCATCGACCTGGTGCGGGTGAATTCCCGGCT
CACGACGTTCGGCCTGTTGGGTGGCACCGTGGTCGGTGGCGCGTTCGCCGCCGGGGCGGAGTATCTGCTCAACCTTTTCC
ACCTGCCCGGTGCGCTGTACGTGATCGTCGCTGCGACCATCGCGGGCGCGGCGCTGTCGATGCACATCCCGAAATGGGTC
GAGGTCACCGCGGGTGAGGTGCCGGCGACATTGAGTTATCACGGCGGCAGCGGCGGTCTGCGACGTGAGCGGCCGTCCGA
GCGGTCCGGCAAGGCGCGCCAGCCGCTGGGCCGTAACACCATCACCGCGCTGTGGGGCAACTGCACGATCAAGGTGATGG
TCGGGTTCCTGTTCCTCTACCCGGCGTTCGTGGCGAAGTCGCACGACGCCACCGGCTGGGAGCAGCTGCGCATCCTCGGC
CTGATCGGCGCCGCGGCCGCCGTCGGCAACTTCGCCGGCAACATGACCGCCGCGCGGCTCGAACTGGGCCACCCGGCGCG
GCTGGTCGTACGCGCGGCCACCGCGGTGACCGCCGTCGCGCTGCTGACCGCGGTCACCGGGAACCTGCTGGTGGCAGCGG
TGGCCACGCTGATCACCTCCGGCGCCAGCGCGATCGCCAAGGCGTCGCTGGATGCGTCGCTTCAGGACGACCTGCCCGAG
GAGTCCAGGGCCTCGGCGTTCGGCCGTTCGGAGTCACTGCTGCAGCTGGCGTGGGTCGCCGGCGGCGCCACCGGGGTGCT
CATCTACACCGACCTGTGGATCGGCTTCACTACGATCACCGCCGTGCTGATTCTCGGTCTGGCCCAGACGGTCGTGAGCT
ACCGCGGCGAATCGCTGATTCCGGGCTTGGGTGGCAACCGCCCGGTGCTGGCCGAACAGGAAGGCCGTCGCTCCGACGCC
GCCGGGGTGGGTTACGAGTGA

Upstream 100 bases:

>100_bases
GTCGGCGGCGGTGTCGGTCAGGCTGTCCATCGCATCCCATAGTGCCGCAGAGCGATACCGGAAAGCCACACCGGTCGGCT
GTCAACCGTCAGTCGGTGCC

Downstream 100 bases:

>100_bases
AACGCGTAGTGGCCGTGCTGGCGGCCGTCGCGGTGCTGGCGACTGCGGCCACGGCGTTCATGGTGTGGCGGCTGACCCGC
GACCACGACCCGGACCTGCC

Product: major facilitator superfamily transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 566; Mature: 566

Protein sequence:

>566_residues
MVDNRGVAGGRDESDGDPEDFRRDARYYPPRPPAGHDHPGMANYPSDGGTYRRPRRQPTPSANRWLPPLDEPTPSGYQYD
PPPGVGAGAGRVTVTRAAAQRSREMGSKMYGLVHRAATADGADKSGLTALTWPVVANFAVDAAMAVALANTLFFAAASGE
SKSKVALYLLITIAPFAVIAPLIGPALDRLQHGRRVALAASFLARTALVVLLIANYDGETGSYQSWVLYPCALGMMVLSK
SFSVLRSAVTPRVLPPSIDLVRVNSRLTTFGLLGGTVVGGAFAAGAEYLLNLFHLPGALYVIVAATIAGAALSMHIPKWV
EVTAGEVPATLSYHGGSGGLRRERPSERSGKARQPLGRNTITALWGNCTIKVMVGFLFLYPAFVAKSHDATGWEQLRILG
LIGAAAAVGNFAGNMTAARLELGHPARLVVRAATAVTAVALLTAVTGNLLVAAVATLITSGASAIAKASLDASLQDDLPE
ESRASAFGRSESLLQLAWVAGGATGVLIYTDLWIGFTTITAVLILGLAQTVVSYRGESLIPGLGGNRPVLAEQEGRRSDA
AGVGYE

Sequences:

>Translated_566_residues
MVDNRGVAGGRDESDGDPEDFRRDARYYPPRPPAGHDHPGMANYPSDGGTYRRPRRQPTPSANRWLPPLDEPTPSGYQYD
PPPGVGAGAGRVTVTRAAAQRSREMGSKMYGLVHRAATADGADKSGLTALTWPVVANFAVDAAMAVALANTLFFAAASGE
SKSKVALYLLITIAPFAVIAPLIGPALDRLQHGRRVALAASFLARTALVVLLIANYDGETGSYQSWVLYPCALGMMVLSK
SFSVLRSAVTPRVLPPSIDLVRVNSRLTTFGLLGGTVVGGAFAAGAEYLLNLFHLPGALYVIVAATIAGAALSMHIPKWV
EVTAGEVPATLSYHGGSGGLRRERPSERSGKARQPLGRNTITALWGNCTIKVMVGFLFLYPAFVAKSHDATGWEQLRILG
LIGAAAAVGNFAGNMTAARLELGHPARLVVRAATAVTAVALLTAVTGNLLVAAVATLITSGASAIAKASLDASLQDDLPE
ESRASAFGRSESLLQLAWVAGGATGVLIYTDLWIGFTTITAVLILGLAQTVVSYRGESLIPGLGGNRPVLAEQEGRRSDA
AGVGYE
>Mature_566_residues
MVDNRGVAGGRDESDGDPEDFRRDARYYPPRPPAGHDHPGMANYPSDGGTYRRPRRQPTPSANRWLPPLDEPTPSGYQYD
PPPGVGAGAGRVTVTRAAAQRSREMGSKMYGLVHRAATADGADKSGLTALTWPVVANFAVDAAMAVALANTLFFAAASGE
SKSKVALYLLITIAPFAVIAPLIGPALDRLQHGRRVALAASFLARTALVVLLIANYDGETGSYQSWVLYPCALGMMVLSK
SFSVLRSAVTPRVLPPSIDLVRVNSRLTTFGLLGGTVVGGAFAAGAEYLLNLFHLPGALYVIVAATIAGAALSMHIPKWV
EVTAGEVPATLSYHGGSGGLRRERPSERSGKARQPLGRNTITALWGNCTIKVMVGFLFLYPAFVAKSHDATGWEQLRILG
LIGAAAAVGNFAGNMTAARLELGHPARLVVRAATAVTAVALLTAVTGNLLVAAVATLITSGASAIAKASLDASLQDDLPE
ESRASAFGRSESLLQLAWVAGGATGVLIYTDLWIGFTTITAVLILGLAQTVVSYRGESLIPGLGGNRPVLAEQEGRRSDA
AGVGYE

Specific function: Unknown

COG id: COG0477

COG function: function code GEPR; Permeases of the major facilitator superfamily

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: To M.tuberculosis Rv0876c [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 59205; Mature: 59205

Theoretical pI: Translated: 9.63; Mature: 9.63

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVDNRGVAGGRDESDGDPEDFRRDARYYPPRPPAGHDHPGMANYPSDGGTYRRPRRQPTP
CCCCCCCCCCCCCCCCCHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
SANRWLPPLDEPTPSGYQYDPPPGVGAGAGRVTVTRAAAQRSREMGSKMYGLVHRAATAD
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHCCC
GADKSGLTALTWPVVANFAVDAAMAVALANTLFFAAASGESKSKVALYLLITIAPFAVIA
CCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCCEEEEHHHHHHHHHHHH
PLIGPALDRLQHGRRVALAASFLARTALVVLLIANYDGETGSYQSWVLYPCALGMMVLSK
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHEECCCCCCCCCCCEEHHHHHHHHHHHHH
SFSVLRSAVTPRVLPPSIDLVRVNSRLTTFGLLGGTVVGGAFAAGAEYLLNLFHLPGALY
HHHHHHHHCCCCCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHH
VIVAATIAGAALSMHIPKWVEVTAGEVPATLSYHGGSGGLRRERPSERSGKARQPLGRNT
HHHHHHHHHHHHHHCCCCCEEEECCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCC
ITALWGNCTIKVMVGFLFLYPAFVAKSHDATGWEQLRILGLIGAAAAVGNFAGNMTAARL
HHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEE
ELGHPARLVVRAATAVTAVALLTAVTGNLLVAAVATLITSGASAIAKASLDASLQDDLPE
ECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCHHHHCCCC
ESRASAFGRSESLLQLAWVAGGATGVLIYTDLWIGFTTITAVLILGLAQTVVSYRGESLI
HHHHHHCCCCHHHHHHHHHCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
PGLGGNRPVLAEQEGRRSDAAGVGYE
CCCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MVDNRGVAGGRDESDGDPEDFRRDARYYPPRPPAGHDHPGMANYPSDGGTYRRPRRQPTP
CCCCCCCCCCCCCCCCCHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
SANRWLPPLDEPTPSGYQYDPPPGVGAGAGRVTVTRAAAQRSREMGSKMYGLVHRAATAD
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHCCC
GADKSGLTALTWPVVANFAVDAAMAVALANTLFFAAASGESKSKVALYLLITIAPFAVIA
CCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCCEEEEHHHHHHHHHHHH
PLIGPALDRLQHGRRVALAASFLARTALVVLLIANYDGETGSYQSWVLYPCALGMMVLSK
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHEECCCCCCCCCCCEEHHHHHHHHHHHHH
SFSVLRSAVTPRVLPPSIDLVRVNSRLTTFGLLGGTVVGGAFAAGAEYLLNLFHLPGALY
HHHHHHHHCCCCCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHH
VIVAATIAGAALSMHIPKWVEVTAGEVPATLSYHGGSGGLRRERPSERSGKARQPLGRNT
HHHHHHHHHHHHHHCCCCCEEEECCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCC
ITALWGNCTIKVMVGFLFLYPAFVAKSHDATGWEQLRILGLIGAAAAVGNFAGNMTAARL
HHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEE
ELGHPARLVVRAATAVTAVALLTAVTGNLLVAAVATLITSGASAIAKASLDASLQDDLPE
ECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCHHHHCCCC
ESRASAFGRSESLLQLAWVAGGATGVLIYTDLWIGFTTITAVLILGLAQTVVSYRGESLI
HHHHHHCCCCHHHHHHHHHCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
PGLGGNRPVLAEQEGRRSDAAGVGYE
CCCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11234002 [H]