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The map label for this gene is 119870556

Identifier: 119870556

GI number: 119870556

Start: 4759562

End: 4760665

Strand: Direct

Name: 119870556

Synonym: Mkms_4527

Alternate gene names: NA

Gene position: 4759562-4760665 (Clockwise)

Preceding gene: 119870555

Following gene: 119870557

Centisome position: 82.96

GC content: 68.48

Gene sequence:

>1104_bases
GTGTCCGCCATCACACCCTTTCGCATCGACGTACCCGATGCCGTCCTGACCGACCTGAAGGATCGCCTCGCCAACACCCG
GTGGCCGGAGGCCGAATGCGTCGACGACTGGAGCCAGGGCATTCCGCTGGCCTACACCCGCGAACTGGCCGACTACTGGG
CGAACGGCTACGACTGGCGCGCCCGCGAGGCCGCGCTCAACCGGTTCGACCAGTTCACCACCGACATCGACGGGCTCGAC
ATCCACTTCATCCACCAGCGCTCGTCGCGGCCCGACGCCTTCCCGCTGATCATCACCCACGGGTGGCCCGGCTCCGTCGT
CGAATTCGACAAGGTGATCGAACCGCTCACCGCCGCCGGCTTCGACGTGGTCTGCCCGTCGCTGCCGGGGTACGGCTTCT
CCGGCAAACCGACGTCGGCGGGGTGGGGCATCGAGCGGATCGCGAAGGCTTGGGACGAGCTCATGGTGCGGCTCGGCTAC
GACCGCTACGGCGCGCAGGGCGGCGACTGGGGTGCGGTGATCACGACGCAGATCGGCCGCAACGAACGCGGGTGCGTCGC
CATCCACACCAACATGCCGATCGGGCGGCCGCCGAAGGACCTCGCGAACCCGACCGACGAGGAACAGCAGACGCTCGCGG
CGATGGCCGAGCGAAAGCGTTGGGGCACCGGGTATTTCCAGCAGCAGGCCACCCGGCCGCAGACGCTGGGCTACGGGCTG
GTCGACTCCCCCGTCGGGCAACTCGCCTGGATCGTCGAGAAGTTCCGGGAATGGAGCGACTGCGACGGCCACCCCGAGAA
CGTGTTCACCAGAGACGAACTGCTCGACAACGTCACGCTGTACTGGGTGACCGCATCGGCCGCGTCGTCGGCCAGGCTGT
ACTGGGAGAGCGGCGTCGGCGGCCGAGGTTCGGGGCCGGTCCGCGTGCCGACCGGTGTGGCGTCCTTCCCGAAGGAGATC
GTCCGGATGCCGCGGCACTGGTGTGAGGACAGCTACCACCTCACCCATTGGACCGACATGCCCCGCGGCGGGCACTTCGC
CGCGTTCGAGCAGCCCGAGTTGTTCGCCGACGACGTCACCGCGTTCTTCGACAGCGTGCGCTGA

Upstream 100 bases:

>100_bases
AGCGCGTCGGCCAAACTCGGCACGCGGACCCGCCACGAATCGGTGTCCCGGGCGCGGCTGCTGCGGCTCATCCCCTGAGC
CTCGTGCGAGGATCGCTGGT

Downstream 100 bases:

>100_bases
CATGCTCGAGGCCGACTACCTCGTCGTCGGCGCGGGGGCGATGGGGATGGCGTTCGTCGACACGCTGATCGCCGAGTCCG
ACGCCACCGTCGTGATCGTC

Product: epocide hydrolase domain-containing protein

Products: NA

Alternate protein names: Epoxide hydratase [H]

Number of amino acids: Translated: 367; Mature: 366

Protein sequence:

>367_residues
MSAITPFRIDVPDAVLTDLKDRLANTRWPEAECVDDWSQGIPLAYTRELADYWANGYDWRAREAALNRFDQFTTDIDGLD
IHFIHQRSSRPDAFPLIITHGWPGSVVEFDKVIEPLTAAGFDVVCPSLPGYGFSGKPTSAGWGIERIAKAWDELMVRLGY
DRYGAQGGDWGAVITTQIGRNERGCVAIHTNMPIGRPPKDLANPTDEEQQTLAAMAERKRWGTGYFQQQATRPQTLGYGL
VDSPVGQLAWIVEKFREWSDCDGHPENVFTRDELLDNVTLYWVTASAASSARLYWESGVGGRGSGPVRVPTGVASFPKEI
VRMPRHWCEDSYHLTHWTDMPRGGHFAAFEQPELFADDVTAFFDSVR

Sequences:

>Translated_367_residues
MSAITPFRIDVPDAVLTDLKDRLANTRWPEAECVDDWSQGIPLAYTRELADYWANGYDWRAREAALNRFDQFTTDIDGLD
IHFIHQRSSRPDAFPLIITHGWPGSVVEFDKVIEPLTAAGFDVVCPSLPGYGFSGKPTSAGWGIERIAKAWDELMVRLGY
DRYGAQGGDWGAVITTQIGRNERGCVAIHTNMPIGRPPKDLANPTDEEQQTLAAMAERKRWGTGYFQQQATRPQTLGYGL
VDSPVGQLAWIVEKFREWSDCDGHPENVFTRDELLDNVTLYWVTASAASSARLYWESGVGGRGSGPVRVPTGVASFPKEI
VRMPRHWCEDSYHLTHWTDMPRGGHFAAFEQPELFADDVTAFFDSVR
>Mature_366_residues
SAITPFRIDVPDAVLTDLKDRLANTRWPEAECVDDWSQGIPLAYTRELADYWANGYDWRAREAALNRFDQFTTDIDGLDI
HFIHQRSSRPDAFPLIITHGWPGSVVEFDKVIEPLTAAGFDVVCPSLPGYGFSGKPTSAGWGIERIAKAWDELMVRLGYD
RYGAQGGDWGAVITTQIGRNERGCVAIHTNMPIGRPPKDLANPTDEEQQTLAAMAERKRWGTGYFQQQATRPQTLGYGLV
DSPVGQLAWIVEKFREWSDCDGHPENVFTRDELLDNVTLYWVTASAASSARLYWESGVGGRGSGPVRVPTGVASFPKEIV
RMPRHWCEDSYHLTHWTDMPRGGHFAAFEQPELFADDVTAFFDSVR

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S33 family [H]

Homologues:

Organism=Homo sapiens, GI4503583, Length=406, Percent_Identity=35.4679802955665, Blast_Score=245, Evalue=6e-65,
Organism=Homo sapiens, GI209862837, Length=406, Percent_Identity=35.4679802955665, Blast_Score=245, Evalue=6e-65,
Organism=Caenorhabditis elegans, GI17564944, Length=402, Percent_Identity=37.0646766169154, Blast_Score=248, Evalue=2e-66,
Organism=Caenorhabditis elegans, GI193207462, Length=405, Percent_Identity=26.4197530864197, Blast_Score=140, Evalue=1e-33,
Organism=Drosophila melanogaster, GI20130139, Length=409, Percent_Identity=35.4523227383863, Blast_Score=223, Evalue=2e-58,
Organism=Drosophila melanogaster, GI24655327, Length=407, Percent_Identity=34.3980343980344, Blast_Score=213, Evalue=2e-55,
Organism=Drosophila melanogaster, GI19922580, Length=406, Percent_Identity=31.5270935960591, Blast_Score=191, Evalue=6e-49,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: =3.3.2.10 [H]

Molecular weight: Translated: 41160; Mature: 41029

Theoretical pI: Translated: 4.78; Mature: 4.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAITPFRIDVPDAVLTDLKDRLANTRWPEAECVDDWSQGIPLAYTRELADYWANGYDWR
CCCCCCCEECCCHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCHHHHHHHHHHHCCCCCCH
AREAALNRFDQFTTDIDGLDIHFIHQRSSRPDAFPLIITHGWPGSVVEFDKVIEPLTAAG
HHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHCC
FDVVCPSLPGYGFSGKPTSAGWGIERIAKAWDELMVRLGYDRYGAQGGDWGAVITTQIGR
CCEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCHHHCCCCCCCCEEEEEECCC
NERGCVAIHTNMPIGRPPKDLANPTDEEQQTLAAMAERKRWGTGYFQQQATRPQTLGYGL
CCCCEEEEECCCCCCCCCHHHCCCCCHHHHHHHHHHHHHHCCCCHHHHHCCCCHHCCCCC
VDSPVGQLAWIVEKFREWSDCDGHPENVFTRDELLDNVTLYWVTASAASSARLYWESGVG
CCCCHHHHHHHHHHHHHHCCCCCCCCCCEEHHHHHCCEEEEEEEECCCCCCEEEEECCCC
GRGSGPVRVPTGVASFPKEIVRMPRHWCEDSYHLTHWTDMPRGGHFAAFEQPELFADDVT
CCCCCCEECCCCHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCCCHHHHHHHH
AFFDSVR
HHHHCCC
>Mature Secondary Structure 
SAITPFRIDVPDAVLTDLKDRLANTRWPEAECVDDWSQGIPLAYTRELADYWANGYDWR
CCCCCCEECCCHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCHHHHHHHHHHHCCCCCCH
AREAALNRFDQFTTDIDGLDIHFIHQRSSRPDAFPLIITHGWPGSVVEFDKVIEPLTAAG
HHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHCC
FDVVCPSLPGYGFSGKPTSAGWGIERIAKAWDELMVRLGYDRYGAQGGDWGAVITTQIGR
CCEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCHHHCCCCCCCCEEEEEECCC
NERGCVAIHTNMPIGRPPKDLANPTDEEQQTLAAMAERKRWGTGYFQQQATRPQTLGYGL
CCCCEEEEECCCCCCCCCHHHCCCCCHHHHHHHHHHHHHHCCCCHHHHHCCCCHHCCCCC
VDSPVGQLAWIVEKFREWSDCDGHPENVFTRDELLDNVTLYWVTASAASSARLYWESGVG
CCCCHHHHHHHHHHHHHHCCCCCCCCCCEEHHHHHCCEEEEEEEECCCCCCEEEEECCCC
GRGSGPVRVPTGVASFPKEIVRMPRHWCEDSYHLTHWTDMPRGGHFAAFEQPELFADDVT
CCCCCCEECCCCHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCCCHHHHHHHH
AFFDSVR
HHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8226695 [H]