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The map label for this gene is accD3 [H]

Identifier: 119870548

GI number: 119870548

Start: 4752410

End: 4753918

Strand: Direct

Name: accD3 [H]

Synonym: Mkms_4519

Alternate gene names: 119870548

Gene position: 4752410-4753918 (Clockwise)

Preceding gene: 119870540

Following gene: 119870555

Centisome position: 82.83

GC content: 74.09

Gene sequence:

>1509_bases
GTGAGCCGGATCGGTGCCCTTCAGCTGCGTGACACCGTCCTGGACGAGGGATCGTTCCGCAGCTGGGACAGCGCGCCGTT
GGCGGTGGCCACCACCGACTCCTACCGGGCCGAACTGGCCGCCGCGTCGGAGAAGACCGGTCTCGACGAAGCCGTGCTGA
CCGGTGAGGGCCGCGTCTTCGGCCGCCGGGTCGCCGTGGTGGCGTGCGAATTCGATTTCCTGGCCGGTTCGATCGGCGTG
GCCGCCGCCGAACGCATCACCGCCGCGGTGCAGCGGGCCACGGCCGAACGGCTCCCGCTGGTGGCCTCGCCGTCCTCGGG
CGGCACCCGGATGCAGGAGGGCACCGTCGCCTTCCTGCAGATGGTCAAGATCGCCGCCGCGGTGCAACTGCACAAGCAGG
CACACCTGCCGTACCTCGTGTATCTGCGTCACCCCACTACCGGCGGGGTGTTCGCGTCGTGGGGTTCCCTCGGCCACGTC
ACCGCGGCCGAACCGGGTGCGCTGATCGGGTTCCTCGGCCCCCGCGTCTACGAACATCTCTACGGCGAACCCTTCCCGGC
GGGCATCCAGACCGCGGAGAACCTGCATCGGCACGGGGTGATCGACGGGGTGGTGCCCCTGGAACTCCTGCGCGCGACGC
TGGACCGGGCGCTCACCGTCCTCGCCGATCCGCCGGGCGCACCCCCGTCGGCACCGCCGGCCGAGCCGCCGGCAGACGTG
CCTGCCTGGACATCGGTCGAGGCGTCGCGGCGGCCGGACCGGCCCGGCGTGGGCTACCTGCTGCGGCACGGCGCCACCGA
CCGCGTCCTGCTGTCGGGGACCGGCCGGGGTGAGGCGGCGACGACGCTGCTGGCGCTGGCCCGGTTCGGCGGGCAGCCCG
CCGTCGTCCTCGGGCAGCAGAGGGTGCTCGGCGGCCCCGATCCAATCCCGGGTCGCTCCGCTCCTGCCCTCCGTGTCGGT
CCGGCGGCGCTGCGGGAGGCGCGCCGCGGGATGGCGCTGGCGGCCGGGCTGCACCTGCCGCTGGTGCTCGTCATCGACAC
CGCGGGACCGGCGCTGACGGTCGAGGCCGAACAGGGCGGACTCGCCGGGGAGATCGCGCGCTGCCTGGCCGACCTGGTCA
CGCTGGACACGCCGACGGTGTCGGTGCTGCTCGGTCAGGGGTCGGGCGGCCCCGCGCTGGCCATGGTGCCCGCCGACCGC
GTGCTGGCCGCGCTGCACGGATGGCTGGCGCCGCTACCGCCCGAAGGCGCGAGCGCCATCGTCTACCGCGACCTCGACCA
CGCCGCGGAACTGGCCGCCGCGCAGGGCGTTCGGTCGGCGGATCTGCTGCGCAACGGCATCGTCGACACGGTCGTCGGCG
AACACCCCGACGCGGCCGACGAACCGCTGGAATTCACGCACCGCCTGTCGGCCACCATCGCCGCCGAACTGCACGCGCTG
CGGGATGTGCCCTCGCAGACCCGGCTGCAGCGGCGGATGGACCGCTACCGCCGTATCGGCCTGCCCTGA

Upstream 100 bases:

>100_bases
TTGAGGGCGTTGCGGCGCTCGGGCCGCTGCATCTCCAGGGTCAGTACCTGGCCGTCGCGGGTGACACCGATCATGCCGCC
ACCTTATATAGCCTTGCGCT

Downstream 100 bases:

>100_bases
TCAGCCGCCGAGTTCGTCGACCGCGGTGGTCAGCGCGGCCGCCTGCTCCTCGAGCCCGCGCTCGTCCGGCGTGGGGCCGC
CGGTGCGCTTGAGCAGTTCG

Product: carboxyl transferase

Products: NA

Alternate protein names: ACCase beta chain [H]

Number of amino acids: Translated: 502; Mature: 501

Protein sequence:

>502_residues
MSRIGALQLRDTVLDEGSFRSWDSAPLAVATTDSYRAELAAASEKTGLDEAVLTGEGRVFGRRVAVVACEFDFLAGSIGV
AAAERITAAVQRATAERLPLVASPSSGGTRMQEGTVAFLQMVKIAAAVQLHKQAHLPYLVYLRHPTTGGVFASWGSLGHV
TAAEPGALIGFLGPRVYEHLYGEPFPAGIQTAENLHRHGVIDGVVPLELLRATLDRALTVLADPPGAPPSAPPAEPPADV
PAWTSVEASRRPDRPGVGYLLRHGATDRVLLSGTGRGEAATTLLALARFGGQPAVVLGQQRVLGGPDPIPGRSAPALRVG
PAALREARRGMALAAGLHLPLVLVIDTAGPALTVEAEQGGLAGEIARCLADLVTLDTPTVSVLLGQGSGGPALAMVPADR
VLAALHGWLAPLPPEGASAIVYRDLDHAAELAAAQGVRSADLLRNGIVDTVVGEHPDAADEPLEFTHRLSATIAAELHAL
RDVPSQTRLQRRMDRYRRIGLP

Sequences:

>Translated_502_residues
MSRIGALQLRDTVLDEGSFRSWDSAPLAVATTDSYRAELAAASEKTGLDEAVLTGEGRVFGRRVAVVACEFDFLAGSIGV
AAAERITAAVQRATAERLPLVASPSSGGTRMQEGTVAFLQMVKIAAAVQLHKQAHLPYLVYLRHPTTGGVFASWGSLGHV
TAAEPGALIGFLGPRVYEHLYGEPFPAGIQTAENLHRHGVIDGVVPLELLRATLDRALTVLADPPGAPPSAPPAEPPADV
PAWTSVEASRRPDRPGVGYLLRHGATDRVLLSGTGRGEAATTLLALARFGGQPAVVLGQQRVLGGPDPIPGRSAPALRVG
PAALREARRGMALAAGLHLPLVLVIDTAGPALTVEAEQGGLAGEIARCLADLVTLDTPTVSVLLGQGSGGPALAMVPADR
VLAALHGWLAPLPPEGASAIVYRDLDHAAELAAAQGVRSADLLRNGIVDTVVGEHPDAADEPLEFTHRLSATIAAELHAL
RDVPSQTRLQRRMDRYRRIGLP
>Mature_501_residues
SRIGALQLRDTVLDEGSFRSWDSAPLAVATTDSYRAELAAASEKTGLDEAVLTGEGRVFGRRVAVVACEFDFLAGSIGVA
AAERITAAVQRATAERLPLVASPSSGGTRMQEGTVAFLQMVKIAAAVQLHKQAHLPYLVYLRHPTTGGVFASWGSLGHVT
AAEPGALIGFLGPRVYEHLYGEPFPAGIQTAENLHRHGVIDGVVPLELLRATLDRALTVLADPPGAPPSAPPAEPPADVP
AWTSVEASRRPDRPGVGYLLRHGATDRVLLSGTGRGEAATTLLALARFGGQPAVVLGQQRVLGGPDPIPGRSAPALRVGP
AALREARRGMALAAGLHLPLVLVIDTAGPALTVEAEQGGLAGEIARCLADLVTLDTPTVSVLLGQGSGGPALAMVPADRV
LAALHGWLAPLPPEGASAIVYRDLDHAAELAAAQGVRSADLLRNGIVDTVVGEHPDAADEPLEFTHRLSATIAAELHALR
DVPSQTRLQRRMDRYRRIGLP

Specific function: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA [H]

COG id: COG0825

COG function: function code I; Acetyl-CoA carboxylase alpha subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AccD/PCCB family [H]

Homologues:

Organism=Escherichia coli, GI1788655, Length=235, Percent_Identity=37.4468085106383, Blast_Score=146, Evalue=3e-36,
Organism=Escherichia coli, GI1786382, Length=271, Percent_Identity=28.7822878228782, Blast_Score=88, Evalue=1e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000438
- InterPro:   IPR000022
- InterPro:   IPR011763
- InterPro:   IPR011762 [H]

Pfam domain/function: PF01039 Carboxyl_trans [H]

EC number: =6.4.1.2 [H]

Molecular weight: Translated: 52376; Mature: 52245

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: PS50980 COA_CT_NTER ; PS50989 COA_CT_CTER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRIGALQLRDTVLDEGSFRSWDSAPLAVATTDSYRAELAAASEKTGLDEAVLTGEGRVF
CCCCCCCHHHHHHHCCCCCCCCCCCCEEEEECCHHHHHHHHHHHHCCCCHHEEECCCCEE
GRRVAVVACEFDFLAGSIGVAAAERITAAVQRATAERLPLVASPSSGGTRMQEGTVAFLQ
EEEEEEEEEEHHHHHCHHHHHHHHHHHHHHHHHHHHHCCEEECCCCCCCCCHHHHHHHHH
MVKIAAAVQLHKQAHLPYLVYLRHPTTGGVFASWGSLGHVTAAEPGALIGFLGPRVYEHL
HHHHHHHHHHHHHCCCCEEEEEECCCCCCCEECCCCCCCEECCCCCCEEEHHHHHHHHHH
YGEPFPAGIQTAENLHRHGVIDGVVPLELLRATLDRALTVLADPPGAPPSAPPAEPPADV
CCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHEEEEECCCCCCCCCCCCCCCCCC
PAWTSVEASRRPDRPGVGYLLRHGATDRVLLSGTGRGEAATTLLALARFGGQPAVVLGQQ
CCCCCCCCCCCCCCCCCCHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHCCCCEEEECCH
RVLGGPDPIPGRSAPALRVGPAALREARRGMALAAGLHLPLVLVIDTAGPALTVEAEQGG
HHCCCCCCCCCCCCCCEEECHHHHHHHHCCCEEEECCCCEEEEEEECCCCEEEEECCCCC
LAGEIARCLADLVTLDTPTVSVLLGQGSGGPALAMVPADRVLAALHGWLAPLPPEGASAI
CHHHHHHHHHHHHHCCCCEEEEEEECCCCCCEEEECCHHHHHHHHHHHCCCCCCCCCCEE
VYRDLDHAAELAAAQGVRSADLLRNGIVDTVVGEHPDAADEPLEFTHRLSATIAAELHAL
EEECHHHHHHHHHHCCCCHHHHHHCCCHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
RDVPSQTRLQRRMDRYRRIGLP
HCCCHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
SRIGALQLRDTVLDEGSFRSWDSAPLAVATTDSYRAELAAASEKTGLDEAVLTGEGRVF
CCCCCCHHHHHHHCCCCCCCCCCCCEEEEECCHHHHHHHHHHHHCCCCHHEEECCCCEE
GRRVAVVACEFDFLAGSIGVAAAERITAAVQRATAERLPLVASPSSGGTRMQEGTVAFLQ
EEEEEEEEEEHHHHHCHHHHHHHHHHHHHHHHHHHHHCCEEECCCCCCCCCHHHHHHHHH
MVKIAAAVQLHKQAHLPYLVYLRHPTTGGVFASWGSLGHVTAAEPGALIGFLGPRVYEHL
HHHHHHHHHHHHHCCCCEEEEEECCCCCCCEECCCCCCCEECCCCCCEEEHHHHHHHHHH
YGEPFPAGIQTAENLHRHGVIDGVVPLELLRATLDRALTVLADPPGAPPSAPPAEPPADV
CCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHEEEEECCCCCCCCCCCCCCCCCC
PAWTSVEASRRPDRPGVGYLLRHGATDRVLLSGTGRGEAATTLLALARFGGQPAVVLGQQ
CCCCCCCCCCCCCCCCCCHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHCCCCEEEECCH
RVLGGPDPIPGRSAPALRVGPAALREARRGMALAAGLHLPLVLVIDTAGPALTVEAEQGG
HHCCCCCCCCCCCCCCEEECHHHHHHHHCCCEEEECCCCEEEEEEECCCCEEEEECCCCC
LAGEIARCLADLVTLDTPTVSVLLGQGSGGPALAMVPADRVLAALHGWLAPLPPEGASAI
CHHHHHHHHHHHHHCCCCEEEEEEECCCCCCEEEECCHHHHHHHHHHHCCCCCCCCCCEE
VYRDLDHAAELAAAQGVRSADLLRNGIVDTVVGEHPDAADEPLEFTHRLSATIAAELHAL
EEECHHHHHHHHHHCCCCHHHHHHCCCHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
RDVPSQTRLQRRMDRYRRIGLP
HCCCHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]