| Definition | Mycobacterium sp. KMS chromosome, complete genome. |
|---|---|
| Accession | NC_008705 |
| Length | 5,737,227 |
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The map label for this gene is fabG [H]
Identifier: 119870460
GI number: 119870460
Start: 4660865
End: 4661626
Strand: Direct
Name: fabG [H]
Synonym: Mkms_4431
Alternate gene names: 119870460
Gene position: 4660865-4661626 (Clockwise)
Preceding gene: 119870458
Following gene: 119870461
Centisome position: 81.24
GC content: 70.6
Gene sequence:
>762_bases ATGCCCGTTCTGGACAGATTCCGTCTCGACGACAAGGTCGTCATCGTCACCGGCGCCTCCTCGGGTCTCGGCGTGGCGTT CGCCAAGGCCTGCGCGGAGGCCGGCGCGGACGTCGTACTGGCCGCCCGCCGCGTGGAGAAACTGGAAGGCACCGCCGAGC TGGTGCGCGCGGCGGGACGCCGTGCGCTGTCGGTGGCCACCGACGTCGTCGACCCGGCCCAGTGCCAGGCGATGGTCGAC GCGGCGATGGCGGAGTTCGGCCACGTCGACGTGCTGGTGAACAACGCCGGGGTGGGCACCGCCGTCCCGGCCACCCGGGA GACTCCGGACGAATTCCGCGCCGTCGTCGACGTGAACCTCAACGGGGCGTACTGGGCGGCGCAGGCCTGCGGCCGGGTGA TGGGCCCGGGCAGTTCGATCGTCAACATCTCGAGCATCCTCGGCATCACCACCGCCGGTCTGCCGCAGGCCGCCTACAGC GCGAGCAAGGCGGCGATCGCCGGGTTGACGCGCGACCTGGCGCAGCAGTGGGGCATCCGCAAGGGCATCCGCGTCAACGC GATCGCACCGGGATTCTTCGAGTCGGAGATGACCGATCAGTACAAACCCGGCTACCTCGAGAGCGTCATCGAGCGTGCGG TGCTGGGTCGCACCGGCGACCCGGAGGAGCTCGCGGCCACGCTGGTCTGGCTGGCGTCGGACGCCGGTGGCTACGTGACC GGGCAGACCATCGTCGTCGACGGCGGCGTCACCATCACCTAG
Upstream 100 bases:
>100_bases AACCCCCGGATTGGTGCTCACTTTAACCAATTCGTTGCCCACCGCCAGCCGGATGGGCGTCGCGAATTTCGCCGGGAGCG GGTGTGATGGGATGACCCCC
Downstream 100 bases:
>100_bases CGCCTCCGGGCCTTACCCGGCGGACAGGAAAGCCTTACCCGCCGGCGGAGAACTCTGGCTTCCGCGCGATTACGCCGTCG CAGCCGCGGCCCGAGGATGG
Product: short-chain dehydrogenase/reductase SDR
Products: NA
Alternate protein names: 3-ketoacyl-acyl carrier protein reductase [H]
Number of amino acids: Translated: 253; Mature: 252
Protein sequence:
>253_residues MPVLDRFRLDDKVVIVTGASSGLGVAFAKACAEAGADVVLAARRVEKLEGTAELVRAAGRRALSVATDVVDPAQCQAMVD AAMAEFGHVDVLVNNAGVGTAVPATRETPDEFRAVVDVNLNGAYWAAQACGRVMGPGSSIVNISSILGITTAGLPQAAYS ASKAAIAGLTRDLAQQWGIRKGIRVNAIAPGFFESEMTDQYKPGYLESVIERAVLGRTGDPEELAATLVWLASDAGGYVT GQTIVVDGGVTIT
Sequences:
>Translated_253_residues MPVLDRFRLDDKVVIVTGASSGLGVAFAKACAEAGADVVLAARRVEKLEGTAELVRAAGRRALSVATDVVDPAQCQAMVD AAMAEFGHVDVLVNNAGVGTAVPATRETPDEFRAVVDVNLNGAYWAAQACGRVMGPGSSIVNISSILGITTAGLPQAAYS ASKAAIAGLTRDLAQQWGIRKGIRVNAIAPGFFESEMTDQYKPGYLESVIERAVLGRTGDPEELAATLVWLASDAGGYVT GQTIVVDGGVTIT >Mature_252_residues PVLDRFRLDDKVVIVTGASSGLGVAFAKACAEAGADVVLAARRVEKLEGTAELVRAAGRRALSVATDVVDPAQCQAMVDA AMAEFGHVDVLVNNAGVGTAVPATRETPDEFRAVVDVNLNGAYWAAQACGRVMGPGSSIVNISSILGITTAGLPQAAYSA SKAAIAGLTRDLAQQWGIRKGIRVNAIAPGFFESEMTDQYKPGYLESVIERAVLGRTGDPEELAATLVWLASDAGGYVTG QTIVVDGGVTIT
Specific function: Unknown
COG id: COG1028
COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]
Homologues:
Organism=Homo sapiens, GI19923817, Length=256, Percent_Identity=31.640625, Blast_Score=128, Evalue=5e-30, Organism=Homo sapiens, GI10190704, Length=251, Percent_Identity=33.8645418326693, Blast_Score=122, Evalue=3e-28, Organism=Homo sapiens, GI40254992, Length=244, Percent_Identity=34.8360655737705, Blast_Score=117, Evalue=1e-26, Organism=Homo sapiens, GI15277342, Length=254, Percent_Identity=31.496062992126, Blast_Score=107, Evalue=9e-24, Organism=Homo sapiens, GI4503301, Length=222, Percent_Identity=29.7297297297297, Blast_Score=100, Evalue=2e-21, Organism=Homo sapiens, GI32483357, Length=256, Percent_Identity=30.859375, Blast_Score=98, Evalue=9e-21, Organism=Homo sapiens, GI7706318, Length=228, Percent_Identity=30.7017543859649, Blast_Score=92, Evalue=4e-19, Organism=Homo sapiens, GI5031737, Length=244, Percent_Identity=28.2786885245902, Blast_Score=88, Evalue=8e-18, Organism=Homo sapiens, GI40254986, Length=194, Percent_Identity=34.5360824742268, Blast_Score=87, Evalue=2e-17, Organism=Homo sapiens, GI66933014, Length=260, Percent_Identity=30.7692307692308, Blast_Score=84, Evalue=1e-16, Organism=Homo sapiens, GI31542939, Length=243, Percent_Identity=29.2181069958848, Blast_Score=82, Evalue=5e-16, Organism=Homo sapiens, GI7705925, Length=246, Percent_Identity=30.0813008130081, Blast_Score=81, Evalue=8e-16, Organism=Homo sapiens, GI4504505, Length=246, Percent_Identity=31.7073170731707, Blast_Score=78, Evalue=6e-15, Organism=Homo sapiens, GI4758504, Length=259, Percent_Identity=29.7297297297297, Blast_Score=77, Evalue=1e-14, Organism=Homo sapiens, GI166795268, Length=208, Percent_Identity=33.1730769230769, Blast_Score=74, Evalue=1e-13, Organism=Homo sapiens, GI33667109, Length=200, Percent_Identity=28, Blast_Score=74, Evalue=2e-13, Organism=Homo sapiens, GI126723750, Length=253, Percent_Identity=27.2727272727273, Blast_Score=72, Evalue=5e-13, Organism=Homo sapiens, GI59889578, Length=233, Percent_Identity=29.6137339055794, Blast_Score=71, Evalue=8e-13, Organism=Homo sapiens, GI224922801, Length=170, Percent_Identity=31.7647058823529, Blast_Score=69, Evalue=5e-12, Organism=Homo sapiens, GI109715829, Length=240, Percent_Identity=25.8333333333333, Blast_Score=67, Evalue=1e-11, Organism=Homo sapiens, GI225579078, Length=204, Percent_Identity=30.8823529411765, Blast_Score=65, Evalue=4e-11, Organism=Homo sapiens, GI20149619, Length=206, Percent_Identity=31.0679611650485, Blast_Score=65, Evalue=5e-11, Organism=Homo sapiens, GI209862901, Length=216, Percent_Identity=27.7777777777778, Blast_Score=65, Evalue=6e-11, Organism=Homo sapiens, GI19923983, Length=216, Percent_Identity=27.7777777777778, Blast_Score=65, Evalue=6e-11, Organism=Escherichia coli, GI1789208, Length=252, Percent_Identity=38.8888888888889, Blast_Score=155, Evalue=3e-39, Organism=Escherichia coli, GI1787335, Length=246, Percent_Identity=33.3333333333333, Blast_Score=132, Evalue=2e-32, Organism=Escherichia coli, GI87082160, Length=253, Percent_Identity=33.9920948616601, Blast_Score=128, Evalue=3e-31, Organism=Escherichia coli, GI1790717, Length=255, Percent_Identity=31.7647058823529, Blast_Score=121, Evalue=5e-29, Organism=Escherichia coli, GI87082100, Length=257, Percent_Identity=34.6303501945525, Blast_Score=120, Evalue=9e-29, Organism=Escherichia coli, GI1788459, Length=250, Percent_Identity=34.8, Blast_Score=118, Evalue=4e-28, Organism=Escherichia coli, GI1789378, Length=250, Percent_Identity=32.8, Blast_Score=106, Evalue=1e-24, Organism=Escherichia coli, GI1787905, Length=251, Percent_Identity=31.8725099601594, Blast_Score=101, Evalue=4e-23, Organism=Escherichia coli, GI2367175, Length=245, Percent_Identity=32.6530612244898, Blast_Score=96, Evalue=2e-21, Organism=Escherichia coli, GI2367365, Length=248, Percent_Identity=31.4516129032258, Blast_Score=92, Evalue=3e-20, Organism=Escherichia coli, GI1786812, Length=256, Percent_Identity=30.46875, Blast_Score=81, Evalue=8e-17, Organism=Escherichia coli, GI1787526, Length=248, Percent_Identity=29.0322580645161, Blast_Score=79, Evalue=2e-16, Organism=Escherichia coli, GI1787820, Length=186, Percent_Identity=29.0322580645161, Blast_Score=67, Evalue=2e-12, Organism=Escherichia coli, GI1789057, Length=257, Percent_Identity=27.6264591439689, Blast_Score=63, Evalue=2e-11, Organism=Caenorhabditis elegans, GI17555706, Length=245, Percent_Identity=33.8775510204082, Blast_Score=127, Evalue=8e-30, Organism=Caenorhabditis elegans, GI17536025, Length=262, Percent_Identity=32.824427480916, Blast_Score=115, Evalue=3e-26, Organism=Caenorhabditis elegans, GI25147288, Length=248, Percent_Identity=31.8548387096774, Blast_Score=115, Evalue=3e-26, Organism=Caenorhabditis elegans, GI17562910, Length=267, Percent_Identity=29.2134831460674, Blast_Score=114, Evalue=4e-26, Organism=Caenorhabditis elegans, GI17562904, Length=270, Percent_Identity=31.4814814814815, Blast_Score=112, Evalue=2e-25, Organism=Caenorhabditis elegans, GI17561402, Length=253, Percent_Identity=30.8300395256917, Blast_Score=112, Evalue=3e-25, Organism=Caenorhabditis elegans, GI17559104, Length=265, Percent_Identity=33.2075471698113, Blast_Score=108, Evalue=2e-24, Organism=Caenorhabditis elegans, GI193204405, Length=263, Percent_Identity=30.4182509505703, Blast_Score=107, Evalue=5e-24, Organism=Caenorhabditis elegans, GI17560676, Length=251, Percent_Identity=29.0836653386454, Blast_Score=107, Evalue=6e-24, Organism=Caenorhabditis elegans, GI17560332, Length=266, Percent_Identity=30.8270676691729, Blast_Score=107, Evalue=8e-24, Organism=Caenorhabditis elegans, GI17536651, Length=258, Percent_Identity=32.5581395348837, Blast_Score=107, Evalue=9e-24, Organism=Caenorhabditis elegans, GI17562906, Length=269, Percent_Identity=32.3420074349442, Blast_Score=105, Evalue=3e-23, Organism=Caenorhabditis elegans, GI17560150, Length=261, Percent_Identity=31.0344827586207, Blast_Score=105, Evalue=3e-23, Organism=Caenorhabditis elegans, GI17538480, Length=267, Percent_Identity=31.0861423220974, Blast_Score=103, Evalue=1e-22, Organism=Caenorhabditis elegans, GI17561272, Length=257, Percent_Identity=33.0739299610895, Blast_Score=102, Evalue=2e-22, Organism=Caenorhabditis elegans, GI72000259, Length=261, Percent_Identity=31.8007662835249, Blast_Score=102, Evalue=3e-22, Organism=Caenorhabditis elegans, GI17562990, Length=269, Percent_Identity=31.5985130111524, Blast_Score=101, Evalue=4e-22, Organism=Caenorhabditis elegans, GI17562908, Length=269, Percent_Identity=31.2267657992565, Blast_Score=99, Evalue=2e-21, Organism=Caenorhabditis elegans, GI17560220, Length=264, Percent_Identity=29.1666666666667, Blast_Score=98, Evalue=4e-21, Organism=Caenorhabditis elegans, GI17531453, Length=272, Percent_Identity=30.5147058823529, Blast_Score=96, Evalue=2e-20, Organism=Caenorhabditis elegans, GI17544670, Length=263, Percent_Identity=27.7566539923954, Blast_Score=96, Evalue=2e-20, Organism=Caenorhabditis elegans, GI71994604, Length=248, Percent_Identity=31.4516129032258, Blast_Score=95, Evalue=3e-20, Organism=Caenorhabditis elegans, GI17565030, Length=274, Percent_Identity=31.3868613138686, Blast_Score=94, Evalue=4e-20, Organism=Caenorhabditis elegans, GI17563726, Length=266, Percent_Identity=31.203007518797, Blast_Score=94, Evalue=5e-20, Organism=Caenorhabditis elegans, GI17551412, Length=264, Percent_Identity=28.7878787878788, Blast_Score=92, Evalue=3e-19, Organism=Caenorhabditis elegans, GI71994600, Length=249, Percent_Identity=29.718875502008, Blast_Score=92, Evalue=4e-19, Organism=Caenorhabditis elegans, GI17538486, Length=267, Percent_Identity=29.9625468164794, Blast_Score=91, Evalue=4e-19, Organism=Caenorhabditis elegans, GI115534694, Length=250, Percent_Identity=30, Blast_Score=85, Evalue=4e-17, Organism=Caenorhabditis elegans, GI17538182, Length=255, Percent_Identity=29.4117647058824, Blast_Score=78, Evalue=5e-15, Organism=Caenorhabditis elegans, GI17570069, Length=170, Percent_Identity=34.1176470588235, Blast_Score=76, Evalue=2e-14, Organism=Caenorhabditis elegans, GI71997402, Length=200, Percent_Identity=30.5, Blast_Score=75, Evalue=2e-14, Organism=Caenorhabditis elegans, GI71982365, Length=190, Percent_Identity=31.0526315789474, Blast_Score=75, Evalue=3e-14, Organism=Caenorhabditis elegans, GI17508895, Length=204, Percent_Identity=27.4509803921569, Blast_Score=74, Evalue=8e-14, Organism=Caenorhabditis elegans, GI17568967, Length=227, Percent_Identity=28.1938325991189, Blast_Score=69, Evalue=2e-12, Organism=Caenorhabditis elegans, GI193203117, Length=198, Percent_Identity=28.2828282828283, Blast_Score=68, Evalue=5e-12, Organism=Caenorhabditis elegans, GI193203115, Length=193, Percent_Identity=29.0155440414508, Blast_Score=67, Evalue=8e-12, Organism=Saccharomyces cerevisiae, GI6322861, Length=239, Percent_Identity=34.3096234309623, Blast_Score=99, Evalue=8e-22, Organism=Saccharomyces cerevisiae, GI6324126, Length=247, Percent_Identity=29.1497975708502, Blast_Score=84, Evalue=2e-17, Organism=Saccharomyces cerevisiae, GI6323882, Length=201, Percent_Identity=34.3283582089552, Blast_Score=75, Evalue=1e-14, Organism=Drosophila melanogaster, GI21357041, Length=252, Percent_Identity=36.1111111111111, Blast_Score=129, Evalue=2e-30, Organism=Drosophila melanogaster, GI28571526, Length=253, Percent_Identity=36.3636363636364, Blast_Score=128, Evalue=4e-30, Organism=Drosophila melanogaster, GI23397609, Length=251, Percent_Identity=36.2549800796813, Blast_Score=123, Evalue=1e-28, Organism=Drosophila melanogaster, GI21355319, Length=249, Percent_Identity=32.1285140562249, Blast_Score=118, Evalue=4e-27, Organism=Drosophila melanogaster, GI24644339, Length=248, Percent_Identity=33.8709677419355, Blast_Score=111, Evalue=4e-25, Organism=Drosophila melanogaster, GI24639444, Length=248, Percent_Identity=33.0645161290323, Blast_Score=108, Evalue=5e-24, Organism=Drosophila melanogaster, GI24643142, Length=256, Percent_Identity=33.203125, Blast_Score=106, Evalue=1e-23, Organism=Drosophila melanogaster, GI24644337, Length=250, Percent_Identity=34, Blast_Score=99, Evalue=3e-21, Organism=Drosophila melanogaster, GI17737361, Length=264, Percent_Identity=29.9242424242424, Blast_Score=89, Evalue=3e-18, Organism=Drosophila melanogaster, GI116007236, Length=201, Percent_Identity=31.3432835820896, Blast_Score=82, Evalue=2e-16, Organism=Drosophila melanogaster, GI21357673, Length=197, Percent_Identity=31.4720812182741, Blast_Score=81, Evalue=8e-16, Organism=Drosophila melanogaster, GI18859837, Length=251, Percent_Identity=29.0836653386454, Blast_Score=76, Evalue=2e-14, Organism=Drosophila melanogaster, GI24641388, Length=216, Percent_Identity=32.4074074074074, Blast_Score=74, Evalue=7e-14, Organism=Drosophila melanogaster, GI21358495, Length=204, Percent_Identity=31.3725490196078, Blast_Score=74, Evalue=1e-13, Organism=Drosophila melanogaster, GI24641232, Length=201, Percent_Identity=29.8507462686567, Blast_Score=74, Evalue=1e-13, Organism=Drosophila melanogaster, GI281364494, Length=202, Percent_Identity=33.6633663366337, Blast_Score=72, Evalue=2e-13, Organism=Drosophila melanogaster, GI24663911, Length=233, Percent_Identity=28.3261802575107, Blast_Score=71, Evalue=6e-13, Organism=Drosophila melanogaster, GI116007238, Length=179, Percent_Identity=32.4022346368715, Blast_Score=71, Evalue=6e-13, Organism=Drosophila melanogaster, GI116007234, Length=201, Percent_Identity=28.8557213930348, Blast_Score=69, Evalue=3e-12, Organism=Drosophila melanogaster, GI24584752, Length=186, Percent_Identity=30.6451612903226, Blast_Score=66, Evalue=2e-11, Organism=Drosophila melanogaster, GI24648693, Length=203, Percent_Identity=31.0344827586207, Blast_Score=65, Evalue=4e-11, Organism=Drosophila melanogaster, GI21355889, Length=203, Percent_Identity=31.0344827586207, Blast_Score=65, Evalue=4e-11, Organism=Drosophila melanogaster, GI24648944, Length=204, Percent_Identity=27.4509803921569, Blast_Score=65, Evalue=4e-11,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR011284 - InterPro: IPR002198 - InterPro: IPR002347 - InterPro: IPR016040 [H]
Pfam domain/function: PF00106 adh_short [H]
EC number: =1.1.1.100 [H]
Molecular weight: Translated: 26135; Mature: 26004
Theoretical pI: Translated: 4.57; Mature: 4.57
Prosite motif: PS00061 ADH_SHORT
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
1.2 %Cys (Translated Protein) 2.0 %Met (Translated Protein) 3.2 %Cys+Met (Translated Protein) 1.2 %Cys (Mature Protein) 1.6 %Met (Mature Protein) 2.8 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MPVLDRFRLDDKVVIVTGASSGLGVAFAKACAEAGADVVLAARRVEKLEGTAELVRAAGR CCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHCCHHHHHHHHCC RALSVATDVVDPAQCQAMVDAAMAEFGHVDVLVNNAGVGTAVPATRETPDEFRAVVDVNL HHHHHHHHCCCHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCHHHCEEEEEECC NGAYWAAQACGRVMGPGSSIVNISSILGITTAGLPQAAYSASKAAIAGLTRDLAQQWGIR CCHHHHHHHHHHHCCCCCCCEEHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCC KGIRVNAIAPGFFESEMTDQYKPGYLESVIERAVLGRTGDPEELAATLVWLASDAGGYVT CCCEEEEECCCCCCHHHCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHEECCCCCEEE GQTIVVDGGVTIT CCEEEEECCEEEC >Mature Secondary Structure PVLDRFRLDDKVVIVTGASSGLGVAFAKACAEAGADVVLAARRVEKLEGTAELVRAAGR CCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHCCHHHHHHHHCC RALSVATDVVDPAQCQAMVDAAMAEFGHVDVLVNNAGVGTAVPATRETPDEFRAVVDVNL HHHHHHHHCCCHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCHHHCEEEEEECC NGAYWAAQACGRVMGPGSSIVNISSILGITTAGLPQAAYSASKAAIAGLTRDLAQQWGIR CCHHHHHHHHHHHCCCCCCCEEHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCC KGIRVNAIAPGFFESEMTDQYKPGYLESVIERAVLGRTGDPEELAATLVWLASDAGGYVT CCCEEEEECCCCCCHHHCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHEECCCCCEEE GQTIVVDGGVTIT CCEEEEECCEEEC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 8759840; 9384377; 9534248; 8654983 [H]