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The map label for this gene is ydfG [C]

Identifier: 119870367

GI number: 119870367

Start: 4556929

End: 4557798

Strand: Direct

Name: ydfG [C]

Synonym: Mkms_4338

Alternate gene names: 119870367

Gene position: 4556929-4557798 (Clockwise)

Preceding gene: 119870366

Following gene: 119870368

Centisome position: 79.43

GC content: 69.89

Gene sequence:

>870_bases
ATGAGTGACTGGACCGCCGCCGACCTCCCCTCCTTCGCCGGCCGCTCGGTGATCGTCACCGGAGCCAACAGCGGCCTCGG
CCTCGTCACCGCCCGCGAACTGGCCCGCGTCGGCGCCGACGTCGTCCTCGCGGTGCGCAACACCGCCAAGGGCGACGAGG
CCGCGGCCACCATGACCGGCAACGTCACCGTCCGCAAACTCGATCTGCAGGACCTCGCGTCGGTGCGCGAGTTCGCCGCG
GGCACCGACAGGGTGGACGTGCTGGTCAACAACGCCGGGATCATGGCGGTGCCCTACGCACGGACCGTCGACGGGTTCGA
GAGCCAGATCGGCACCAACCACCTCGGCCACTTCGCGCTGACCAATCTGCTGCTGCCCAAGATCACCGACCGCGTGGTCA
CGGTGTCGTCGTTCATGCACGTCCTCGGGCGCATCAACCTCGACGACCTCAACTGGAAGGCGCGGCCGTACTCGGCGTGG
CTGGCCTACGGCCAGTCGAAACTGGCCAACCTCCTGTTCACCAGCGAACTGCAGAACCGGTTGCGTCGCGCCGGTTCCCC
GGTGCGTGCTCTGGCGGCCCACCCCGGGTATTCGCACACCAACCTGCAGGGTCAGTCCGGCCGCAAGCTCGGCGACGCGT
TGATGGCCTTCGGCGGTGAGTACTTCGCGACCGACGCCGACTTCGGCGCCCGCCAGACGCTGTACGCGGTGGCCCAGGAC
CTGCCCGGGGACACCTTCGTCGGCCCGAAGTTCGCGATGCGCGGGCCGACCGGTCCGGTGTGGCGCACGCCGCTGGCCCG
CGACATGAAGACCGCCGCGGCGCTGTGGGAGCTGTCCGAGCAGCTCACCGGCACCCGGTTCCCGCTCTAG

Upstream 100 bases:

>100_bases
CCAACGAGGCCGAGAAGTACGGCAAGGACATCGAGGCGATCCTCACCGGCTTCACCGTCGCCCCGAAGAAGTAGCCGCAC
CCGCCGATACAGTGGCAACC

Downstream 100 bases:

>100_bases
GATTTCCGCCGGACCGTCCGGGTGCGGTAACCTCGACGCCGCATCACGGCGAGGGTGGCCAGGCCACCGTTATCGACGGG
AACACACTGTTCACGCTGTT

Product: short-chain dehydrogenase/reductase SDR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 289; Mature: 288

Protein sequence:

>289_residues
MSDWTAADLPSFAGRSVIVTGANSGLGLVTARELARVGADVVLAVRNTAKGDEAAATMTGNVTVRKLDLQDLASVREFAA
GTDRVDVLVNNAGIMAVPYARTVDGFESQIGTNHLGHFALTNLLLPKITDRVVTVSSFMHVLGRINLDDLNWKARPYSAW
LAYGQSKLANLLFTSELQNRLRRAGSPVRALAAHPGYSHTNLQGQSGRKLGDALMAFGGEYFATDADFGARQTLYAVAQD
LPGDTFVGPKFAMRGPTGPVWRTPLARDMKTAAALWELSEQLTGTRFPL

Sequences:

>Translated_289_residues
MSDWTAADLPSFAGRSVIVTGANSGLGLVTARELARVGADVVLAVRNTAKGDEAAATMTGNVTVRKLDLQDLASVREFAA
GTDRVDVLVNNAGIMAVPYARTVDGFESQIGTNHLGHFALTNLLLPKITDRVVTVSSFMHVLGRINLDDLNWKARPYSAW
LAYGQSKLANLLFTSELQNRLRRAGSPVRALAAHPGYSHTNLQGQSGRKLGDALMAFGGEYFATDADFGARQTLYAVAQD
LPGDTFVGPKFAMRGPTGPVWRTPLARDMKTAAALWELSEQLTGTRFPL
>Mature_288_residues
SDWTAADLPSFAGRSVIVTGANSGLGLVTARELARVGADVVLAVRNTAKGDEAAATMTGNVTVRKLDLQDLASVREFAAG
TDRVDVLVNNAGIMAVPYARTVDGFESQIGTNHLGHFALTNLLLPKITDRVVTVSSFMHVLGRINLDDLNWKARPYSAWL
AYGQSKLANLLFTSELQNRLRRAGSPVRALAAHPGYSHTNLQGQSGRKLGDALMAFGGEYFATDADFGARQTLYAVAQDL
PGDTFVGPKFAMRGPTGPVWRTPLARDMKTAAALWELSEQLTGTRFPL

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI225579078, Length=311, Percent_Identity=43.0868167202572, Blast_Score=182, Evalue=4e-46,
Organism=Homo sapiens, GI186928839, Length=300, Percent_Identity=40.6666666666667, Blast_Score=176, Evalue=2e-44,
Organism=Homo sapiens, GI166795268, Length=288, Percent_Identity=42.3611111111111, Blast_Score=170, Evalue=1e-42,
Organism=Homo sapiens, GI10190746, Length=304, Percent_Identity=39.4736842105263, Blast_Score=159, Evalue=3e-39,
Organism=Homo sapiens, GI19923931, Length=259, Percent_Identity=42.0849420849421, Blast_Score=144, Evalue=7e-35,
Organism=Homo sapiens, GI7706523, Length=299, Percent_Identity=36.4548494983278, Blast_Score=130, Evalue=1e-30,
Organism=Homo sapiens, GI193804850, Length=297, Percent_Identity=36.3636363636364, Blast_Score=126, Evalue=2e-29,
Organism=Homo sapiens, GI146231950, Length=297, Percent_Identity=39.0572390572391, Blast_Score=122, Evalue=4e-28,
Organism=Homo sapiens, GI20149619, Length=244, Percent_Identity=30.7377049180328, Blast_Score=68, Evalue=8e-12,
Organism=Escherichia coli, GI1787820, Length=205, Percent_Identity=26.8292682926829, Blast_Score=64, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17558006, Length=209, Percent_Identity=37.3205741626794, Blast_Score=109, Evalue=1e-24,
Organism=Caenorhabditis elegans, GI72001364, Length=222, Percent_Identity=37.3873873873874, Blast_Score=108, Evalue=4e-24,
Organism=Caenorhabditis elegans, GI17505416, Length=250, Percent_Identity=30.4, Blast_Score=92, Evalue=4e-19,
Organism=Caenorhabditis elegans, GI17532805, Length=308, Percent_Identity=27.5974025974026, Blast_Score=89, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI17532791, Length=308, Percent_Identity=25.974025974026, Blast_Score=89, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI193207620, Length=305, Percent_Identity=28.1967213114754, Blast_Score=88, Evalue=5e-18,
Organism=Caenorhabditis elegans, GI71992402, Length=294, Percent_Identity=29.2517006802721, Blast_Score=85, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI17535059, Length=289, Percent_Identity=28.3737024221453, Blast_Score=67, Evalue=8e-12,
Organism=Caenorhabditis elegans, GI32565532, Length=123, Percent_Identity=34.9593495934959, Blast_Score=66, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6324820, Length=224, Percent_Identity=31.25, Blast_Score=89, Evalue=1e-18,
Organism=Saccharomyces cerevisiae, GI6324148, Length=230, Percent_Identity=29.1304347826087, Blast_Score=74, Evalue=4e-14,
Organism=Drosophila melanogaster, GI28573296, Length=291, Percent_Identity=41.9243986254296, Blast_Score=158, Evalue=4e-39,
Organism=Drosophila melanogaster, GI24586328, Length=290, Percent_Identity=40, Blast_Score=148, Evalue=5e-36,
Organism=Drosophila melanogaster, GI45554248, Length=284, Percent_Identity=40.8450704225352, Blast_Score=147, Evalue=8e-36,
Organism=Drosophila melanogaster, GI24640117, Length=284, Percent_Identity=40.8450704225352, Blast_Score=147, Evalue=8e-36,
Organism=Drosophila melanogaster, GI22024069, Length=287, Percent_Identity=40.7665505226481, Blast_Score=144, Evalue=6e-35,
Organism=Drosophila melanogaster, GI19921754, Length=293, Percent_Identity=38.9078498293515, Blast_Score=144, Evalue=6e-35,
Organism=Drosophila melanogaster, GI161076371, Length=202, Percent_Identity=44.0594059405941, Blast_Score=130, Evalue=9e-31,
Organism=Drosophila melanogaster, GI24656154, Length=286, Percent_Identity=34.2657342657343, Blast_Score=122, Evalue=3e-28,
Organism=Drosophila melanogaster, GI19922628, Length=286, Percent_Identity=34.2657342657343, Blast_Score=122, Evalue=3e-28,
Organism=Drosophila melanogaster, GI45553409, Length=237, Percent_Identity=37.1308016877637, Blast_Score=117, Evalue=6e-27,
Organism=Drosophila melanogaster, GI24647948, Length=237, Percent_Identity=37.1308016877637, Blast_Score=117, Evalue=6e-27,
Organism=Drosophila melanogaster, GI24647946, Length=237, Percent_Identity=37.1308016877637, Blast_Score=117, Evalue=7e-27,
Organism=Drosophila melanogaster, GI20129347, Length=202, Percent_Identity=35.1485148514851, Blast_Score=115, Evalue=5e-26,
Organism=Drosophila melanogaster, GI24647931, Length=214, Percent_Identity=36.4485981308411, Blast_Score=79, Evalue=4e-15,
Organism=Drosophila melanogaster, GI23397609, Length=205, Percent_Identity=33.1707317073171, Blast_Score=75, Evalue=7e-14,
Organism=Drosophila melanogaster, GI28571526, Length=212, Percent_Identity=31.6037735849057, Blast_Score=69, Evalue=4e-12,
Organism=Drosophila melanogaster, GI21357041, Length=212, Percent_Identity=30.188679245283, Blast_Score=65, Evalue=5e-11,

Paralogues:

None

Copy number: 1300 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 31034; Mature: 30902

Theoretical pI: Translated: 9.64; Mature: 9.64

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDWTAADLPSFAGRSVIVTGANSGLGLVTARELARVGADVVLAVRNTAKGDEAAATMTG
CCCCCCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHCCCCEEEEECCCCCCCCCEEEEEC
NVTVRKLDLQDLASVREFAAGTDRVDVLVNNAGIMAVPYARTVDGFESQIGTNHLGHFAL
CEEEEEECHHHHHHHHHHHCCCCCEEEEEECCCEEEECCHHHHHHHHHHHCCCHHHHHHH
TNLLLPKITDRVVTVSSFMHVLGRINLDDLNWKARPYSAWLAYGQSKLANLLFTSELQNR
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
LRRAGSPVRALAAHPGYSHTNLQGQSGRKLGDALMAFGGEYFATDADFGARQTLYAVAQD
HHHCCCCCEEHHCCCCCCCCCCCCCCCCHHHHHHHHHCCCEEECCCCCCHHHHHHHHHHC
LPGDTFVGPKFAMRGPTGPVWRTPLARDMKTAAALWELSEQLTGTRFPL
CCCCCCCCCCEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
SDWTAADLPSFAGRSVIVTGANSGLGLVTARELARVGADVVLAVRNTAKGDEAAATMTG
CCCCCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHCCCCEEEEECCCCCCCCCEEEEEC
NVTVRKLDLQDLASVREFAAGTDRVDVLVNNAGIMAVPYARTVDGFESQIGTNHLGHFAL
CEEEEEECHHHHHHHHHHHCCCCCEEEEEECCCEEEECCHHHHHHHHHHHCCCHHHHHHH
TNLLLPKITDRVVTVSSFMHVLGRINLDDLNWKARPYSAWLAYGQSKLANLLFTSELQNR
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
LRRAGSPVRALAAHPGYSHTNLQGQSGRKLGDALMAFGGEYFATDADFGARQTLYAVAQD
HHHCCCCCEEHHCCCCCCCCCCCCCCCCHHHHHHHHHCCCEEECCCCCCHHHHHHHHHHC
LPGDTFVGPKFAMRGPTGPVWRTPLARDMKTAAALWELSEQLTGTRFPL
CCCCCCCCCCEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8383668 [H]