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The map label for this gene is arsC [H]

Identifier: 119870365

GI number: 119870365

Start: 4555884

End: 4556246

Strand: Direct

Name: arsC [H]

Synonym: Mkms_4336

Alternate gene names: 119870365

Gene position: 4555884-4556246 (Clockwise)

Preceding gene: 119870364

Following gene: 119870366

Centisome position: 79.41

GC content: 67.22

Gene sequence:

>363_bases
GTGGCATCGACTGACGGGCGGCCCGCCGCCGTGATCTACCACAACCCGAAGTGCTCGACGTCGCGTAAGACCCTGGATCT
GTTGCGCGAGAACGGTATCGAGCCCGACGTGGTGCAGTACCTCAAGACACCGCCGTCACGCGCCGAACTCGCCGCGATGA
TCGAGGCCGCCGGGATCGACGTGCGCACCGCGGTCCGCAAACGCGAAGCGCTGTACAACGAACTGAATCTGGCCGACGCG
ACCGACGACGAGTTGCTCGACGCGCTCGCCGAGCACCCGATCCTCATCGAGCGGCCGTTCGTGGTGACCGACAAGGGCAC
CCGGCTGGCCCGGCCGATCGACGCGGTGCGCGAGATCCTGTGA

Upstream 100 bases:

>100_bases
GCAACTGACCGTGCTGTCCATCGCCCCGCTGCTGGCCAACACGATCCGCGCGGTGTTCGACAACGGTTCGGTGACAAGCC
TTTTCGACGGGTCGGCGTAA

Downstream 100 bases:

>100_bases
CAGCCCGCCGCGTCACCGCGGCCGCGGCCGCGCTGCTGGTCCTCGCCATCGGCGGATGCGGCGCGGAAACCCCTGACTAC
CAATCGGTCTGGAGCACGTC

Product: arsenate reductase

Products: NA

Alternate protein names: Arsenical pump modifier [H]

Number of amino acids: Translated: 120; Mature: 119

Protein sequence:

>120_residues
MASTDGRPAAVIYHNPKCSTSRKTLDLLRENGIEPDVVQYLKTPPSRAELAAMIEAAGIDVRTAVRKREALYNELNLADA
TDDELLDALAEHPILIERPFVVTDKGTRLARPIDAVREIL

Sequences:

>Translated_120_residues
MASTDGRPAAVIYHNPKCSTSRKTLDLLRENGIEPDVVQYLKTPPSRAELAAMIEAAGIDVRTAVRKREALYNELNLADA
TDDELLDALAEHPILIERPFVVTDKGTRLARPIDAVREIL
>Mature_119_residues
ASTDGRPAAVIYHNPKCSTSRKTLDLLRENGIEPDVVQYLKTPPSRAELAAMIEAAGIDVRTAVRKREALYNELNLADAT
DDELLDALAEHPILIERPFVVTDKGTRLARPIDAVREIL

Specific function: Reduction of arsenate [As(V)] to arsenite [As(III)]. This protein expands the substrate specificity of ArsAB pump which can extrude arsenite and antimonite to allow for arsenate pumping and resistance [H]

COG id: COG1393

COG function: function code P; Arsenate reductase and related proteins, glutaredoxin family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ArsC family [H]

Homologues:

Organism=Escherichia coli, GI1789918, Length=111, Percent_Identity=54.0540540540541, Blast_Score=121, Evalue=2e-29,
Organism=Escherichia coli, GI1788841, Length=112, Percent_Identity=47.3214285714286, Blast_Score=107, Evalue=3e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006659
- InterPro:   IPR006660
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF03960 ArsC [H]

EC number: =1.20.4.1 [H]

Molecular weight: Translated: 13262; Mature: 13131

Theoretical pI: Translated: 4.96; Mature: 4.96

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASTDGRPAAVIYHNPKCSTSRKTLDLLRENGIEPDVVQYLKTPPSRAELAAMIEAAGID
CCCCCCCCEEEEEECCCCCCHHHHHHHHHHCCCCHHHHHHHCCCCCHHHHHHHHHHHCCC
VRTAVRKREALYNELNLADATDDELLDALAEHPILIERPFVVTDKGTRLARPIDAVREIL
HHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCEEEECCEEEECCCCCHHHHHHHHHHHC
>Mature Secondary Structure 
ASTDGRPAAVIYHNPKCSTSRKTLDLLRENGIEPDVVQYLKTPPSRAELAAMIEAAGID
CCCCCCCEEEEEECCCCCCHHHHHHHHHHCCCCHHHHHHHCCCCCHHHHHHHHHHHCCC
VRTAVRKREALYNELNLADATDDELLDALAEHPILIERPFVVTDKGTRLARPIDAVREIL
HHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCEEEECCEEEECCCCCHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3021763; 1703401; 1704144 [H]