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The map label for this gene is kdpE [H]

Identifier: 119870326

GI number: 119870326

Start: 4520509

End: 4521189

Strand: Direct

Name: kdpE [H]

Synonym: Mkms_4296

Alternate gene names: 119870326

Gene position: 4520509-4521189 (Clockwise)

Preceding gene: 119870325

Following gene: 119870327

Centisome position: 78.79

GC content: 68.58

Gene sequence:

>681_bases
GTGACCCGCGTGCTCGTCGTCGACGACGAACCGCAGATCCTGCGGGCGCTGAAGATCAACCTGTCGGTGCGCGGCTACGA
GGTGACCACCGCCGCCACCGGCGCCGAGGCGCTGCGTTCGGCCGCCGATCACAAACCCGACGTCATCGTGCTCGACCTCG
GACTGCCCGACATGTCCGGCATCGAGGTGCTGGCCGGCCTGCGCGGTTGGTTGTCGGCACCGGTCATCGTGCTGTCCGCC
CGCACCGACTCCTCCGACAAGGTCGAGGCGCTCGACGCCGGCGCCGACGACTACGTCACCAAACCCTTTGGGATGGACGA
GTTCCTGGCCCGGTTGCGGGCCGCCGTGCGCCGCGCGACCAAAGAGTCCGACGGCGACGAACCGGTGGTGGTGACCGGAT
CATTCACCGTCGACCTGGCCGCCAAGCGGGTCGTCAAGAACGGCGCGGAGGTGCACCTCACCCCGACCGAGTGGGGCATG
CTCGAGATGCTGGTGCGCCACCGCGGCAAGCTCGTCGGCCGGGAGGAGTTGCTCAAGGAGGTGTGGGGTCCGGCGTACGC
GAAGGAGACGCACTATCTGCGGGTCTATCTCGCCCAGCTGCGCCGCAAACTCGAAGACGACCCGTCCCGTCCTCGGCACC
TGCTCACCGAGGCGGGTATGGGGTACCGGTTCCAGCAGTAG

Upstream 100 bases:

>100_bases
GATTCGTCGAGGCGATGGGCGGTACGGTCACCGCGAACGACACCCCGGGCGGGGGCCTGACCGTCGAAATCGACCTCGCC
GCACCGCAGGAGGCCCACGC

Downstream 100 bases:

>100_bases
CGAATCCCGCCGAGCAGACGCAAATGTCCCGATTCAGGGCTGTTTTCGGGCACTTTTGCGTCTGCTCGCCGAGGTCGGGG
CCGGTCGGTATAGCGTGCCG

Product: two component transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 226; Mature: 225

Protein sequence:

>226_residues
MTRVLVVDDEPQILRALKINLSVRGYEVTTAATGAEALRSAADHKPDVIVLDLGLPDMSGIEVLAGLRGWLSAPVIVLSA
RTDSSDKVEALDAGADDYVTKPFGMDEFLARLRAAVRRATKESDGDEPVVVTGSFTVDLAAKRVVKNGAEVHLTPTEWGM
LEMLVRHRGKLVGREELLKEVWGPAYAKETHYLRVYLAQLRRKLEDDPSRPRHLLTEAGMGYRFQQ

Sequences:

>Translated_226_residues
MTRVLVVDDEPQILRALKINLSVRGYEVTTAATGAEALRSAADHKPDVIVLDLGLPDMSGIEVLAGLRGWLSAPVIVLSA
RTDSSDKVEALDAGADDYVTKPFGMDEFLARLRAAVRRATKESDGDEPVVVTGSFTVDLAAKRVVKNGAEVHLTPTEWGM
LEMLVRHRGKLVGREELLKEVWGPAYAKETHYLRVYLAQLRRKLEDDPSRPRHLLTEAGMGYRFQQ
>Mature_225_residues
TRVLVVDDEPQILRALKINLSVRGYEVTTAATGAEALRSAADHKPDVIVLDLGLPDMSGIEVLAGLRGWLSAPVIVLSAR
TDSSDKVEALDAGADDYVTKPFGMDEFLARLRAAVRRATKESDGDEPVVVTGSFTVDLAAKRVVKNGAEVHLTPTEWGML
EMLVRHRGKLVGREELLKEVWGPAYAKETHYLRVYLAQLRRKLEDDPSRPRHLLTEAGMGYRFQQ

Specific function: Member of the two-component regulatory system kdpD/kdpE involved in the regulation of the kdp operon [H]

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1786911, Length=224, Percent_Identity=51.7857142857143, Blast_Score=229, Evalue=1e-61,
Organism=Escherichia coli, GI1787375, Length=228, Percent_Identity=36.4035087719298, Blast_Score=143, Evalue=1e-35,
Organism=Escherichia coli, GI1789809, Length=227, Percent_Identity=32.15859030837, Blast_Score=127, Evalue=7e-31,
Organism=Escherichia coli, GI1790552, Length=221, Percent_Identity=33.4841628959276, Blast_Score=121, Evalue=5e-29,
Organism=Escherichia coli, GI1786599, Length=225, Percent_Identity=33.3333333333333, Blast_Score=119, Evalue=1e-28,
Organism=Escherichia coli, GI1786784, Length=229, Percent_Identity=30.5676855895196, Blast_Score=116, Evalue=1e-27,
Organism=Escherichia coli, GI87082012, Length=222, Percent_Identity=31.981981981982, Blast_Score=115, Evalue=2e-27,
Organism=Escherichia coli, GI1790860, Length=220, Percent_Identity=34.0909090909091, Blast_Score=112, Evalue=2e-26,
Organism=Escherichia coli, GI2367329, Length=227, Percent_Identity=32.15859030837, Blast_Score=109, Evalue=1e-25,
Organism=Escherichia coli, GI1788394, Length=229, Percent_Identity=29.2576419213974, Blast_Score=107, Evalue=5e-25,
Organism=Escherichia coli, GI1789402, Length=227, Percent_Identity=32.5991189427313, Blast_Score=103, Evalue=1e-23,
Organism=Escherichia coli, GI1790863, Length=228, Percent_Identity=27.6315789473684, Blast_Score=97, Evalue=6e-22,
Organism=Escherichia coli, GI1787229, Length=227, Percent_Identity=29.9559471365639, Blast_Score=94, Evalue=6e-21,
Organism=Escherichia coli, GI1788550, Length=122, Percent_Identity=39.344262295082, Blast_Score=89, Evalue=4e-19,
Organism=Escherichia coli, GI145693140, Length=233, Percent_Identity=25.3218884120172, Blast_Score=82, Evalue=2e-17,
Organism=Escherichia coli, GI1790299, Length=114, Percent_Identity=36.8421052631579, Blast_Score=69, Evalue=2e-13,
Organism=Escherichia coli, GI1790437, Length=133, Percent_Identity=32.3308270676692, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI1788712, Length=113, Percent_Identity=31.858407079646, Blast_Score=64, Evalue=8e-12,
Organism=Escherichia coli, GI145693157, Length=123, Percent_Identity=30.8943089430894, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI1788905, Length=122, Percent_Identity=32.7868852459016, Blast_Score=61, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 24989; Mature: 24858

Theoretical pI: Translated: 6.37; Mature: 6.37

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRVLVVDDEPQILRALKINLSVRGYEVTTAATGAEALRSAADHKPDVIVLDLGLPDMSG
CCEEEEECCCHHHHHHHEEEEEEECEEEEEHHHHHHHHHHHHCCCCCEEEEECCCCCCCH
IEVLAGLRGWLSAPVIVLSARTDSSDKVEALDAGADDYVTKPFGMDEFLARLRAAVRRAT
HHHHHHHHHHHCCCEEEEEECCCCCCCHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHH
KESDGDEPVVVTGSFTVDLAAKRVVKNGAEVHLTPTEWGMLEMLVRHRGKLVGREELLKE
CCCCCCCCEEEECCEEHHHHHHHHHHCCCEEEECCCHHHHHHHHHHHHCCCCCHHHHHHH
VWGPAYAKETHYLRVYLAQLRRKLEDDPSRPRHLLTEAGMGYRFQQ
HCCCCHHCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCCCCCC
>Mature Secondary Structure 
TRVLVVDDEPQILRALKINLSVRGYEVTTAATGAEALRSAADHKPDVIVLDLGLPDMSG
CEEEEECCCHHHHHHHEEEEEEECEEEEEHHHHHHHHHHHHCCCCCEEEEECCCCCCCH
IEVLAGLRGWLSAPVIVLSARTDSSDKVEALDAGADDYVTKPFGMDEFLARLRAAVRRAT
HHHHHHHHHHHCCCEEEEEECCCCCCCHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHH
KESDGDEPVVVTGSFTVDLAAKRVVKNGAEVHLTPTEWGMLEMLVRHRGKLVGREELLKE
CCCCCCCCEEEECCEEHHHHHHHHHHCCCEEEECCCHHHHHHHHHHHHCCCCCHHHHHHH
VWGPAYAKETHYLRVYLAQLRRKLEDDPSRPRHLLTEAGMGYRFQQ
HCCCCHHCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1532388; 8905232; 9278503 [H]